Clinical trials: Communications Disorders
End Stage Renal Disease, Chronic Kidney Diseases
Shared Decision Making in Dialysis
Older patients ≥65 years with chronic kidney disease (CKD) face challenges in decision making about dialysis. These patients report little effort by physicians to elicit treatment preferences, discuss prognoses, or explain the…
- Trial name
- DIAL-SDM (NCT04392440)
- Testing
- DIAL-SDM, usual care
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Rochester
Aphasia
Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia
Transcranial Magnetic Stimulation (TMS) has been demonstrated to improve language function in subjects with chronic aphasia in a number of small studies, many of which did not include a control group.
- Trial name
- NCT03651700
- Testing
- Active TMS, CILT
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- H. Branch Coslett
Aphasia, Acquired
Effects of rTMS on Brain Activation in Aphasia
This study will investigate the use of repetitive transcranial magnetic stimulation (rTMS), a non-invasive brain stimulation method, to improve word-finding abilities in Veterans and non-Veterans with chronic language problems…
- Trial name
- NCT03292471
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- VA Office of Research and Development
SARS-CoV2 Infection
Rural Tailored COVID-19 Communication to Promote SARS-CoV-2 Antibody Testing in Saliva
This study seeks to evaluate communication strategies for better encouraging understanding and uptake of salivary SARS-CoV-2 antibody testing among individuals residing in rural Northern Michigan.
- Trial name
- NCT06085547
- Testing
- General SARS-CoV-2 Communication, Rural-Targeted SARS-CoV-2 Communication
- Where
- United States
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Michigan State University
Aphasia
Transcranial Direct Stimulation (tDCS) and Behavioral Intervention in Aphasia
We hypothesize patients who have difficulty with word recall (naming pictures) due to a stroke will experience greater benefit in word recall after receiving a combination of transcranial direct current stimulation (tDCS) and…
- Trial name
- NCT02226796
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Minnesota
HIV/AIDS, HIV Infections
Enhancing Sexual Safety: Couples' Communication and HIV Testing Among YMSM
The purpose of this study is to compare different ways to deliver the couples HIV Testing and Counseling (CHTC) intervention that is suited for adolescents and young adults.
- Trial name
- WeTestATN156 (NCT04289116)
- Testing
- We Test, IHTC
- Where
- 2 sites in United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Florida State University
Aphasia, Stroke
Dosage and Predictors of Naming Treatment Response in Aphasia
This study examines aphasia treatment response among Veterans and non-Veterans living with aphasia. It seeks to identify cognitive and neural factors which are predictive of positive response to treatment targeting naming…
- Trial name
- NCT02005016
- Testing
- Naming therapy
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- VA Office of Research and Development
Developmental Language Disorder, Specific Language Impairment
Retrieval-Based Word Learning in Developmental Language Disorder: Verb Learning
Children with developmental language disorder (DLD; also referred to as specific language impairment) experience a significant deficit in language ability that is longstanding and harmful to the children's academic, social, and…
- Conditions
- Developmental Language Disorder, Specific Language Impairment, Language Development
- Trial name
- NCT06001866
- Testing
- Retrieval-based verb learning: Repeated Spaced Retrieval condition, Retrieval-based verb learning: Repeated Study condition
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Purdue University
Hoarding Disorder, Hoarding
Hoarding Disorder Treatment With Virtual Reality
This study explores whether a facilitated peer support group called Buried in Treasures (BIT) and a virtual reality decluttering practice can help individuals with clutter challenges.
- Conditions
- Hoarding Disorder, Hoarding, Clutter
- Trial name
- HDVR (NCT03828461)
- Testing
- Facilitated group therapy with behavioral practice; 16 weeks
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Stanford University
Fragile X Syndrome, FXS
A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome
This is a single-center, randomized, double-blind, 2-period crossover study to explore the effects of BPN14770 on cognitive function and behavior in subjects with Fragile X Syndrome.
- Conditions
- Fragile X Syndrome, FXS, Fra(X) Syndrome
- Trial name
- NCT03569631
- Testing
- BPN14770
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Tetra Discovery Partners
Hypertension, Stroke
Controlling Hypertension Outcomes by Improved Communication & Engagement
This randomized control study tested the feasibility of two communication enhancement interventions: one with veterans who had a stroke and demonstrated poorly controlled hypertension; the other with VA primary care providers who…
- Trial name
- CHOICE (NCT01134887)
- Testing
- Informational Guide for Patients, Video-Assisted Coaching, Monograph for Physicians
- Where
- 2 sites in United States
- Volunteers
- 26 people
- Sponsor
- VA Office of Research and Development
Aphasia, CVA
Treatment Intensity - Apraxia of Speech
A growing neurorehabilitation literature suggests that intense treatment may be desired to maximize the effects of therapy following neurologic injury.
- Conditions
- Aphasia, CVA, Apraxia of Speech
- Trial name
- NCT02332915
- Testing
- Sound Production Treatment (SPT)
- Where
- 2 sites in United States
- Volunteers
- 36 people
- Sponsor
- VA Office of Research and Development
Intellectual Disability, Autism
Enhancing Genomic Laboratory Reports to Enhance Communication and Empower Patients
Current lab reports are designed to communicate results from the laboratory to the provider; they are not designed to be accessible to patients.
- Conditions
- Intellectual Disability, Autism, Multiple Congenital Anomalies
- Trial name
- NCT02504502
- Testing
- enhanced genomic report
- Volunteers
- 52 people
- Sponsor
- Geisinger Clinic
Primary Progressive Aphasia, Behavioral Variant of Frontotemporal Dementia
Assessment of Hyperphosphorylated Tau PET Binding in Primary Progressive Aphasia and Frontotemporal Dementia
This study is designed to learn more about overall tau burden in the brain of patients with Primary Progressive Aphasia (PPA) and Frontotemporal Dementia.
- Conditions
- Primary Progressive Aphasia, Behavioral Variant of Frontotemporal Dementia, Frontotemporal Dementia, Behavioral Variant
- Trial name
- SLD3 (NCT02736695)
- Testing
- F-18 AV 1451
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Mayo Clinic
Primary Progressive Aphasia
Treating Primary Progressive Aphasia (PPA) Using tDCS
This is a double-blind, sham-controlled, crossover study in which subjects with the non-fluent/agrammatic and semantic variants of primary progressive aphasia (naPPA and svPPA, respectively) will undergo language testing and…
- Trial name
- NCT04566731
- Testing
- Transcranial Direct Current Stimulation (tDCS), Modified Contraint-Induced Language Therapy (mCILT)
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Pennsylvania
Breast Cancer
Narrative Visualization for Breast Cancer Survivors' Physical Activity
This study tests the feasibility and acceptability of a physical activity intervention that combines use of a wearable activity monitor with a scrapbook.
- Trial name
- NCT03612596
- Testing
- Narrative visualization, Standard self-regulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Advance Care Planning, Palliative Care
Palliative Care Educator
The investigators propose to conduct a stepped wedge cluster randomized trial of an advance care planning (ACP) educator-led intervention among hospitalized patients aged 65 and over, or any patient with Alzheimer's Disease and…
- Conditions
- Advance Care Planning, Palliative Care, Alzheimer's Disease and Related Dementias, Doctor-patient Communication
- Trial name
- VIDEO-PCE (NCT04857060)
- Testing
- ACP Educator led, video assisted discussion
- Where
- 2 sites in United States
- Volunteers
- 11,174 people
- Sponsor
- Tufts Medical Center
Bone Marrow Transplant, Information Disclosure
Effects of Digital Stories Intervention on Psychosocial Well-being
Patients and caregivers undergoing hematopoietic stem cell transplantation often continue to experience anxiety, depression, isolation, and other psychosocial distress.
- Conditions
- Bone Marrow Transplant, Information Disclosure, Hematopoietic Stem Cell Transplantation, Psychosocial Health
- Trial name
- NCT03654599
- Testing
- Baseline Surveys, Digital Stories Intervention, Information Control Intervention
- Where
- United States
- Volunteers
- 202 people
- Sponsor
- Arizona State University
Critical Illness, Chronic Disease
Improving Communication About Serious Illness
The purpose of this study is to improve care delivered to patients with serious illness by enhancing communication among patients, families, and clinicians in the outpatient setting.
- Conditions
- Critical Illness, Chronic Disease, Terminal Care, Palliative Care
- Trial name
- ICSI (NCT01933789)
- Testing
- Communication Feedback Form for Patients with Serious Illness
- Where
- 6 sites in United States
- Volunteers
- 817 people
- Sponsor
- University of Washington
Attention Deficit Hyperactivity Disorder, Dyslexia
Effects of Atomoxetine on Brain Activation During Attention & Reading Tasks in Participants With ADHD & Comorbid Dyslexia
This study will evaluate the effects of atomoxetine on brain activation during attention and reading tasks via functional Magnetic Resonance Imaging (fMRI) in participants ages 10 to 16 years old with ADHD and comorbid dyslexia
- Trial name
- NCT00716274
- Testing
- Atomoxetine
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Eli Lilly and Company