Clinical trials: Community Pneumonia
Pneumonia, Malaria
Zambia Integrated Management of Malaria and Pneumonia Study
The purpose of the study is to demonstrate the effectiveness and feasibility of community-based management of pneumonia and malaria by community health workers (CHWs) in a rural district of Zambia.
- Trial name
- ZIMMAPS (NCT00513500)
- Testing
- Coartem and amoxicillin, Coartem
- Where
- Zambia
- Volunteers
- 3,125 people
- Sponsor
- Boston University
Tuberculosis, COVID-19
Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19
Tuberculosis (TB) is now the commonest cause of death in many African countries. Globally, ~35% (almost 1 in 3) of TB cases are 'missed' (remain undiagnosed or undetected).
- Conditions
- Tuberculosis, COVID-19, HIV Infections
- Trial name
- NCT05220163
- Testing
- CAD, Xpert
- Where
- 3 sites in South Africa, Zambia and 1 more
- Volunteers
- 26,200 people, healthy volunteers welcome
- Sponsor
- University of Cape Town
Severe Community-acquired Pneumonia (sCAP)
Epidemiology and Current Practices in Severe Community-Acquired Pneumonia
The goal of this observational study is to learn more about severe community-acquired pneumonia (sCAP) in adults who need hospital or intensive care.
- Trial name
- PLENITUDE (NCT07301099)
- Where
- Colombia
- Volunteers
- 2,588 people
- Sponsor
- Universidad de la Sabana
Community Acquired Pneumonia (CAP)
Clinical Characteristics and Outcome of Patients With Community Acquired Pneumonia
the goal of this observational study is to evaluate the clinical characteristic and outcomes of patients with community-acquired pneumonia admitted to Sohag University Hospital.
- Trial name
- NCT06716099
- Volunteers
- 100 people
- Sponsor
- Sohag University
Community Acquired Bacterial Pneumonia
Use of Ceftaroline in Hospitalized Patients With Community Acquired Pneumonia
Community-acquired bacterial pneumonia, which is often called CAP, is a bacterial infection in the lungs and is treated with antibiotics. Sometimes people need to be in the hospital to be treated for CAP.
- Trial name
- CAP (NCT01605864)
- Testing
- Efficacy of ceftaroline
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Albany Medical College
Pneumonia
A Study to Compare the Efficacy and Safety of Levofloxacin in the Treatment of Children With Community-acquired Pneumonia in the Hospital or Outpatient Setting
The purpose of this study is to determine the safety and efficacy of levofloxacin in the treatment of children with community acquired pneumonia.
- Trial name
- NCT00034736
- Testing
- Levofloxacin
- Volunteers
- 691 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Community-Acquired Pneumonia, Antimicrobial Stewardship
Reducing Antimicrobial Overuse Through Targeted Therapy for Patients With Community-Acquired Pneumonia
The purpose of this study is to reduce the exposure of broad-spectrum antimicrobials by optimizing the rapid detection of CAP pathogens and improving rates of de-escalation following negative cultures.
- Conditions
- Community-Acquired Pneumonia, Antimicrobial Stewardship, Point-of-Care Testing
- Trial name
- NCT05568654
- Testing
- Rapid Diagnostic Testing, Pharmacist-led de-escalation
- Where
- 12 sites in United States
- Volunteers
- 28,580 people
- Sponsor
- The Cleveland Clinic
Respiratory Infection, Pneumonia
Efficacy and Safety of Trimodulin (BT588) in Subjects With CAP Including COVID-19 Pneumonia
The main objectives of the trial are to assess the efficacy and safety of trimodulin as adjunctive treatment to standard of care (SoC) compared to placebo plus SoC in adult hospitalized subjects with non-severe community-acquired…
- Conditions
- Respiratory Infection, Pneumonia, Community-acquired Pneumonia, Acute Respiratory Distress Syndrome
- Trial name
- TRICOVID (NCT05531149)
- Testing
- Trimodulin
- Where
- 64 sites in Argentina, Austria and 12 more
- Volunteers
- 107 people
- Sponsor
- Biotest
Respiratory Tract Infections
Mycoplasma Infection Rate and Macrolides Resistance in Children With Acute Respiratory Tract Infection
In recent years, mycoplasma pneumoniae caused more than 30% of respiratory infections in children in China, among which the detection rate of drug-resistant mycoplasma pneumoniae was higher than 90%.
- Trial name
- NCT04126304
- Testing
- Azithromycin, non-macrolides antibiotics, Mycoplasma detection
- Volunteers
- 2,312 people
- Sponsor
- Shanghai Children's Medical Center
Covid19, SARS-CoV2 Infection
Reducing Spread of COVID-19 in a University Community Setting: Role of a Low-Cost Reusable Form-Fitting Fabric Mask
The primary aim of the proposed research is to test the role of a newly developed reusable form-fitting fabric mask in reducing the spread of COVID-19 in a community setting comprising undergraduate students living in dormitories…
- Trial name
- NCT04979858
- Testing
- Focal Mask
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology
Community-acquired Pneumonia
pedCAPNETZ - Community Acquired Pneumonia (CAP) in Childhood and Adolescence
Establishment of a study network and patient cohort for pediatric CAP
- Trial name
- pedCAPNETZ (NCT04047108)
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Hannover Medical School
Coronavirus, Coronavirus Infection
COVID-19 Infection and Transmission in Exposed, Confined and Community-based Infants
According to epidemiological models, the seroprevalence of SARS-CoV-2 infection in Île-de-France as of 11 May was between 10 and 15%.
- Conditions
- Coronavirus, Coronavirus Infection, Covid19, Sars-CoV2
- Trial name
- COVIDOCRECHE (NCT04413968)
- Testing
- Rapid detection test, Nasopharyngeal swab, Stool collection
- Where
- 11 sites in France
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pneumonia Childhood, Pneumonia
Lung Ultrasound for Guiding Antibiotic Use in Pediatric Pneumonia
Pneumonia is a major cause of illness and death in children, with an annual incidence of about 3.3 per 1,000 in those under five years old, many requiring hospitalization.
- Conditions
- Pneumonia Childhood, Pneumonia, Lung Ultrasound, Antibiotic Stewardship
- Trial name
- LUSCAP (NCT06921993)
- Testing
- LUNG ULTRASOUND
- Where
- 18 sites in United States, Israel and 1 more
- Volunteers
- 659 people
- Sponsor
- Meyer Children's Hospital IRCCS
Health Behavior, Health Care Utilization
COVID-19: Healthy Oregon (Oregon Saludable): Together We Can (Juntos Podemos) Phase II
The global SARS-CoV-2 pandemic that causes the severe respiratory illness COVID-19 is the worst health crisis that the United States has faced in a century.
- Trial name
- OSJP (NCT05082935)
- Testing
- Phase II Promotores de Salud, Phase I Promotores de Salud Outreach
- Where
- United States
- Volunteers
- 1,463 people
- Sponsor
- University of Oregon
Pneumonia
An Open, Prospective, Randomized, Multicenter Study of the Efficacy and Safety of Intravenous Followed by Oral Azithromycin Versus Cefuroxime Alone or With Oral Erythromycin for the Treatment of Chinese Patients Who Were Hospitalized for Pneumonia
To validate the efficacy and safety of azithromycin for the treatment of Chinese patients hospitalized with community-acquired pneumonia (CAP), compared with cefuroxime or the combination of cefuroxime plus oral erythromycin.
- Trial name
- NCT00648726
- Testing
- cefuroxime plus erythromycin, azithromycin (Zithromax), cefuroxime
- Where
- 5 sites in China
- Volunteers
- 139 people
- Sponsor
- Pfizer
Community-acquired Pneumonia
Surviving Pneumonia
The study aims to explore risk factors for poor prognosis among patients admitted with community-acquired pneumonia (CAP). During a 5-year study period, all patients (aged ≥ 18 years) admitted with CAP at North Zealand Hospital…
- Trial name
- NCT03795662
- Testing
- No intervention
- Where
- Denmark
- Volunteers
- 2,500 people
- Sponsor
- Nordsjaellands Hospital
Community-acquired Pneumonia
Study of the Efficacy and Safety of Antioxidants Astaxanthin as an Adjuvant Therapy for Community Acquired Pneumonia Patients.
Community acquired pneumonia (CAP) is one of the most common and morbid conditions encountered in clinical practice, which causes serious morbidity worldwide.
- Trial name
- NCT06334874
- Testing
- Astaxanthin Oral Capsule
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Future University in Egypt
COVID-19, SARS-CoV-2
COVID-19 Pandemic Response Network
Coronavirus Disease 19 (COVID-19) represents an unprecedented challenge to the operations and population health management efforts of health care systems around the world.
- Conditions
- COVID-19, SARS-CoV-2, Coronavirus, Influenza -Like Illness
- Trial name
- NCT04320862
- Where
- United States
- Volunteers
- 9,207 people, healthy volunteers welcome
- Sponsor
- Duke University
General Surgery, Disease Outbreaks
Short-term Outcome of Covid-19 Surgical Patients: Case-series of a High-risk Area Community Hospital
The investigators retrospectively evaluated all the patients operated in a high-risk community hospital from the first Italian case of Covid-19 (February 21st) to the April 10th (in order to have at least a 30-days follow-up).
- Trial name
- NCT04430062
- Testing
- Surgical procedures performed under general anesthesia
- Where
- Italy
- Volunteers
- 14 people
- Sponsor
- Azienda Socio Sanitaria Territoriale di Lodi
Community-acquired Pneumonia
Corticosteroid Treatment for Community-Acquired Pneumonia - The STEP Trial
Background: An intact hypothalami-pituitary-adrenal (HPA) axis with an effective intracellular anti-inflammatory activity of glucocorticoids is indispensable for host survival during stress upon exposure to an infectious agent.
- Trial name
- STEP (NCT00973154)
- Testing
- Prednisone
- Where
- 7 sites in Switzerland
- Volunteers
- 800 people
- Sponsor
- University Hospital, Basel, Switzerland