Clinical trials: Community-based
Innate Inflammatory Response, Vaccination
PFAS Exposure and Immune Response to Vaccination in Adults
This clinical trial aims to investigate how exposure to Perfluorononanoic acid (PFNA), a type of per- and polyfluoroalkyl substance (PFAS), affects the immune response to the standard tetanus and diphtheria (Td) vaccine.
- Conditions
- Innate Inflammatory Response, Vaccination, Diphtheria, Tetanus
- Trial name
- NCT06588530
- Testing
- TENIVAC
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Substance Use, Sexual Behavior
A Library-based Prevention Intervention for Adolescents Affected by Parental Drug Use
This study's goal is to partner with public libraries to prevent substance use and sexual risk-taking among urban African American adolescents (ages 13-16) affected by parental drug use.
- Conditions
- Substance Use, Sexual Behavior, Adolescent Behavior
- Trial name
- NCT05033821
- Testing
- Adapted FOY+ImPACT
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
HIV Infections
Prevalence and Risk Factors of HIV Infections in Transgender and Non-binary People in Flanders and Brussels (Belgium)
Background: HIV prevalence and sexual risk have been estimated very high for transgender people. However, the limited sampling and data collection methods used in current research on transgender people potentially led to…
- Trial name
- NCT04930614
- Testing
- Survey on socio-demographic variables and healthcare-seeking, sexual and drug-using behaviour
- Where
- Belgium
- Volunteers
- 1,068 people, healthy volunteers welcome
- Sponsor
- Centre for Evidence-Based Practice, Belgium
Physical Activity, Obesity Prevention
Social Mechanisms for Promoting Physical Activity in After School Programs for Underserved Middle School Youth
The primary goal of the Connect feasibility trial was to develop and test the feasibility of a physical activity (PA) social-climate-based intervention within pre-existing after school programs (ASPs) that targets youth social…
- Trial name
- NCT03850821
- Testing
- Connect Social Mechanisms Intervention
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Covid19
Community-based Post-exposure Prophylaxis for COVID-19
Specifically identified Ayurvedic preparations is recommended by ministry of AYUSH as post-exposure prophylaxis to efficaciously prevent a negative person who has come into contact with COVID-19-positive.
- Trial name
- NCT04920773
- Testing
- Guduchi Ghanvati, Standard guidelines
- Where
- 2 sites in India
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- NMP Medical Research Institute
Obesity, Cardiometabolic Syndrome
A Study Comparing the Health Effects of Two Diets Following UK Dietary Guidance in People Living With Overweight or Obesity
There are two parts to this study: 1. The investigators will study if the benefit from eating a healthy, balanced diet depends on the types of food processing in the diet.
- Conditions
- Obesity, Cardiometabolic Syndrome, Overweight
- Trial name
- UPDATE (NCT05627570)
- Testing
- Healthy, balanced Diet A, Healthy, balanced Diet B, Behavioural support intervention
- Where
- United Kingdom
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University College, London
HIV
Community-based Combination HIV Prevention in Tanzanian Women
The Phase II trial will assess the feasibility, acceptance, safety, pathways, and initial effectiveness of a community-based combination HIV prevention intervention among bar-based female sex workers in Iringa, Tanzania.
- Trial name
- NCT02281578
- Testing
- Community-based combination HIV prevention intervention, Standard of care HIV services
- Where
- Tanzania
- Volunteers
- 496 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Contraception, Family Planning
Community Based Distribution of Injectable Contraceptives in Tigray, Ethiopia
The purpose of this study was to demonstrate that with appropriate training, the provision of injectable contraceptives by community based reproductive health agents (CBRHAs) does not significantly differ from low-level…
- Conditions
- Contraception, Family Planning, Task Shifting, Community Based Distribution
- Trial name
- CBDDMPA (NCT01288274)
- Testing
- Community Based administration of DMPA
- Where
- 3 sites in Ethiopia
- Volunteers
- 1,062 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Sepsis
Neonatal Sepsis, Evaluation, Bangladesh
More than half of under-five deaths in Bangladesh occur in the first month of life (neonatal period), and a substantial proportion of these deaths are due to infections (sepsis).
- Trial name
- NCT01333982
- Testing
- Amoxycillin, Gentamicin, Counselling
- Where
- Bangladesh
- Volunteers
- 20,000 people, healthy volunteers welcome
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
Low Birth Weight
Community Kangaroo Mother Care for Improving Child Survival and Brain Development in Low Birth Weight Newborns
While newborn and child survival remains a priority, optimal development of survivors is receiving increasing attention. Interventions that impact both survival and development should be prioritized for action.
- Trial name
- CKMC-DEV (NCT02631343)
- Testing
- KMC, Essential newborn care
- Where
- India
- Volunteers
- 550 people, healthy volunteers welcome
- Sponsor
- Society for Applied Studies
Overweight, Obesity
Healthy Futures Project: A Community Based Obesity Prevention Program
The purpose of this research is to increase community awareness about the relationship between physical activity, screen time, and nutrition and how these factors influence healthy weight management.
- Trial name
- SWITCH (NCT00685555)
- Testing
- Switch active lifestyles brought to you by MediaWise, Switch active lifestyles from MediaWise
- Where
- United States
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- National Institute on Media and the Family
Pediatric Obesity, Health Behavior, Risky
Growing Healthy Children and Families in Rural Arkansas
Childhood obesity is a national problem with racial and ethnic disparities specifically among Hispanic children. The primary purpose of this study is to develop and implement a culturally appropriate healthy eating intervention…
- Trial name
- NCT06565455
- Testing
- Growing Healthy Children and Families in Rural Arkansas
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Cervical Cancer
Vietnamese Women's Health Project III
The purpose of this protocol is to understand the extent of symptom perception and preventive care-seeking among Vietnamese American women and their impact on cervical cancer screening from the perspectives and experiences of key…
- Trial name
- NCT01704235
- Testing
- Demographic Form and Semi-Structured Interview Guide
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- OHSU Knight Cancer Institute
Postpartum
Home-based Delivery of the Contraceptive Implant in Postpartum Guatemalan Women
Abstract Background: Postpartum contraception is important to prevent unintended and closely spaced pregnancies following childbirth.
- Trial name
- NCT04005391
- Testing
- Offer of Participant's Choice of Contraception Method
- Where
- 2 sites in United States, Guatemala
- Volunteers
- 208 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Severe Community-acquired Pneumonia
Diagnosis and Treatment Strategy Optimization of Severe Pneumonia Based on Multi-omics Data Integration
Severe community-acquired pneumonia still has a high incidence and mortality, but the molecular mechanism and prognostic biomarkers of severe community-acquired pneumonia caused by different pathogens are still unclear, and the…
- Trial name
- NCT06288074
- Testing
- Multi-omics tests
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Nicotine Dependence, Substance Use Disorders
Healthy People Initiative (HPI)
Addictions do not occur in isolation. Tackling addictions requires addressing social determinants such as isolation, homelessness, marginalization, and unemployment.
- Trial name
- HPI (NCT03506867)
- Testing
- Life skills, training, education and work/volunteer opportunities, Usual Care
- Where
- Canada
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Smart Community- and Home-based Integrated Care Services
Effectiveness of a Smart Community- and Home-based Integrated Care Services System for Elderly People
In recent years, the widespread application of emerging information technologies such as artificial intelligence, the Internet of Things, big data, cloud computing, and 5G has made "smart " a new breakthrough in the integrated…
- Trial name
- ESCHIC (NCT06848036)
- Testing
- smart integrated care services
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liu Zhihan
Mental Health Wellness
Testing the Feasibility of a Sports-based Mental Health Promotion Intervention for Adolescents in Nepal
Each year, one in five adolescents experiences a mental disorder like depression or anxiety, and the rate is rising. Depression is a common mental disorder, one of the leading global causes of Disability Adjusted Life Years among…
- Trial name
- NCT05394311
- Testing
- sports based mental health promotion program
- Where
- Nepal
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Transcultural Psychosocial Organization Nepal
Social Isolation in Older Adults, Loneliness
Community-Based Social Connection Intervention Program to Improve Cardiovascular and Brain Health
This study evaluates the effectiveness of a community-based social connection intervention program (SCIP) designed to reduce social isolation and loneliness and improve cardiovascular and brain health among older adults living in…
- Conditions
- Social Isolation in Older Adults, Loneliness, Stroke, Cognitive Decline
- Trial name
- NCT07319663
- Testing
- Social Connection Intervention Program (SCIP): Community activities, peer-support groups, and home-based coaching to reduce social isolation and loneliness.
- Where
- Ecuador
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Universidad de Especialidades Espiritu Santo
HIV Prevention, Sexually Transmitted Infections (STI)
California MEPS Hub
The California Hub for HIV/SUD Prevention Research with Reentry Populations addresses the question: "Can the evidence-based MEPS intervention be adapted and implemented at a range of organizations to effectively serve a wider…
- Conditions
- HIV Prevention, Sexually Transmitted Infections (STI), Preexposure Prophylaxis (PrEP), Incarceration
- Trial name
- NCT07433985
- Testing
- Mobile Enhanced Prevention Support (MEPS), Control
- Where
- 3 sites in United States
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles