Clinical trials: Community-dwelling
Cardiovascular Diseases, Renal Disease
OPTIMISation of Cardio-renal-metabolic-pulmonary Disease Guideline Adherence in High Risk Community Dwelling Individuals
Cardiovascular disease (CVD) causes a quarter of all deaths in the United Kingdom (UK). This is the single biggest area where the National Health Service (NHS) can save lives by detecting and treating risk factors early.
- Conditions
- Cardiovascular Diseases, Renal Disease, Metabolic Disease, Pulmonary Disease
- Trial name
- OPTIMISE (NCT06444711)
- Testing
- NICE guidance
- Where
- United Kingdom
- Volunteers
- 138 people
- Sponsor
- University of Leeds
Malaria, Pneumonia
Assessment of Use of Rapid Diagnostic Testing in the Context of Home Management With ACTs
This study is to assess the value of incorporating a malaria RDT based strategy in HMM. The primary activity of the study wil be a two armed cluster randomised trial in two study sites in Uganda, one in Ghana and one in Burkina…
- Trial name
- NCT00720811
- Testing
- Artemether-lumefantrine combination, amoxycillin, paracetamol
- Where
- 4 sites in Burkina Faso, Ghana and 1 more
- Volunteers
- 6,456 people
- Sponsor
- Mbarara University of Science and Technology
Parkinson's Disease (PD)
Observational Study Evaluating Robotic Spinal Mobilization in 16 Parkinson's Disease Participants. The Study Recorded Changes in Mobility, Sit-to-stand Performance, and Pain Scores After a 2-week Intervention With the BackHug Device.
The goal of this completed observational pilot study was to evaluate the immediate and short-term clinical effects of robotic spinal mobilization on motor and non-motor symptoms in community-dwelling adults with Parkinson's…
- Trial name
- NCT07384364
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Pacla Medical Limited
Healthcare Inequities, Health Intervention
Ethnic Minorities Experiences of Healthcare Intervention
As ethnic diversity in Britain continues to grow, so do the health needs in a society with many different ethnic backgrounds, including the need for personalised healthcare.
- Conditions
- Healthcare Inequities, Health Intervention, Study Focus is Healthcare Interventions and Health Inequalities
- Trial name
- EM (NCT07211698)
- Testing
- Qualitative study - Phase 1, Qualitative study - Phase 2
- Where
- United Kingdom
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
PreDiabetes
Personalizing Sleep Interventions to Prevent Type 2 Diabetes in Community Dwelling Adults With Pre-Diabetes
This study will use continuous glucose monitoring and actigraphy to examine whether a personalized, daily sleep extension intervention improves glucose regulation for community dwelling, sleep-restricted adults with pre-diabetes.
- Trial name
- NCT03398902
- Testing
- Sleep extension, Habitual sleep
- Where
- United States
- Volunteers
- 393 people
- Sponsor
- New York University
Vitamin D Deficiency, Arterial Stiffness
Vitamin D and Arterial Stiffness in Elderly
Investigators will examine arterial stiffness and pulse waveform analysis. Subjects with vitamin D insufficiency will be recruited.
- Trial name
- NCT03649802
- Testing
- Low dose vitamin D3, High dose vitamin D3
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Frailty in Older Adults, Intrinsic Capacity
Optimizing INtrinsic Capacity for Functional INdependence and to Impede FrailTY in Older Adults: Adaptation of the WHO-ICOPE for Healthy Ageing in Singapore
The goal of this intervention study is to screen and identify frailty and decline in intrinsic capacity (physical and mental capacities) in community-dwelling older adults in Singapore, and to evaluate whether early…
- Conditions
- Frailty in Older Adults, Intrinsic Capacity, Age-related Functional Decline, Healthy Ageing
- Trial name
- INFINITY-ICOPE (NCT07477561)
- Testing
- INFINITY-ICOPE programme
- Where
- Singapore
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Sengkang General Hospital
Peripheral Artery Disease, Intermittent Claudication
Home-based Circuit Training for People With Intermittent Claudication
The purpose of the study is to assess the feasibility of undertaking a randomised controlled trial investigating the effectiveness of a 12-week home-based exercise programme for people with intermittent claudication.
- Trial name
- WALKSTRONG (NCT05059899)
- Testing
- Exercise group
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- Coventry University
Dementia, Cardiovascular Risk Factor
Cerebrovascular Correlates of Dementia in Rural Communities - The Three Villages Study
This study aims to assess the prevalence and severity of dementia in an established cohort of community-dwelling older adults living in three neighboring rural Ecuadorian villages (Atahualpa, El Tambo, and Prosperidad), as well…
- Conditions
- Dementia, Cardiovascular Risk Factor, Atherosclerosis, Cerebral Small Vessel Diseases
- Trial name
- NCT04123171
- Testing
- Neuroimaging studies
- Where
- 2 sites in Ecuador
- Volunteers
- 600 people
- Sponsor
- Universidad de Especialidades Espiritu Santo
Nursing Home, Veterans
Disseminating a Dashboard for VA Purchased Community Nursing Homes
Objectives: The purpose of this proposal is to evaluate the impact of the CNH Dashboard implementation on the quality of VA Purchased CNH care relative to other CNH facilities, and to evaluate the quality of Veteran-specific care…
- Conditions
- Nursing Home, Veterans, Functional Impairment, Quality of Care
- Trial name
- CNHDashboard (NCT02674698)
- Testing
- Access to the CNH Dashboard Step 1, Access to the CNH Dashboard Step 2, Access to the CNH Dashboard Step 3
- Volunteers
- 18 people
- Sponsor
- Providence VA Medical Center
Smart Community- and Home-based Integrated Care Services
Effectiveness of a Smart Community- and Home-based Integrated Care Services System for Elderly People
In recent years, the widespread application of emerging information technologies such as artificial intelligence, the Internet of Things, big data, cloud computing, and 5G has made "smart " a new breakthrough in the integrated…
- Trial name
- ESCHIC (NCT06848036)
- Testing
- smart integrated care services
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Liu Zhihan
Community-dwelling Seniors
Dual-task Training to Prevent Cognitive Decline in Community-dwelling Older Adults: A Pilot Pragmatic RCT
Objectives: This study aims to explore the feasibility and acceptance of group-based dual-task training for prevention of cognitive decline in a pragmatic setting for community-dwelling older adults.
- Trial name
- NCT06648707
- Testing
- Dual-task training
- Where
- Hong Kong
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Non-Pharmacological Interventions
Applied Research on a Non-pharmacological Intervention Program for Older Adults With Subjective Cognitive Decline
This study aims to verify the short-term and long-term effects of a group-based non-pharmacological intervention program for community-dwelling older adults with subjective cognitive decline, and to evaluate its implementation…
- Trial name
- NCT07629531
- Testing
- non-pharmacological interventions, Waiting List
- Volunteers
- 218 people
- Sponsor
- China Medical University, China
Old Age, Fall
Effects of Lower Limb Positive Pressure on the Balance of Community-dwelling Older Adults
With the onset of the sixth decade in life, degenerative processes affect the neuromuscular system in terms of losses in muscle strength (dynapenia) and muscle mass (sarcopenia).
- Trial name
- NCT04636645
- Testing
- Normal treadmill, Anti-gravity treadmill with lower limb positive pressure, Anti-gravity treadmill with without lower limb positive pressure
- Where
- Pakistan
- Volunteers
- 90 people
- Sponsor
- Riphah International University
Frailty, Cognitive Dysfunction
Trajectory of Frailty and Cognitive Dysfunction in Older Adults
To explore the heterogeneity of the development trend of frailty and cognitive function of older adults.
- Conditions
- Frailty, Cognitive Dysfunction, Community-dwelling Older Adults
- Trial name
- NCT06276166
- Testing
- No intervention
- Volunteers
- 934 people, healthy volunteers welcome
- Sponsor
- Zheng Li
Cognitive Dysfunction, Dietary Habits
Nutrition, gUT Microbiota, and BRain AgINg: the NutBrain Study
Epidemiological evidence suggests that healthy diet is associated with a slowdown of cognitive decline leading to dementia, but the underlying mechanisms are still partially unexplored.
- Trial name
- NutBrain (NCT04461951)
- Testing
- Lifestyles (exposure)
- Where
- Italy
- Volunteers
- 643 people, healthy volunteers welcome
- Sponsor
- IRCCS National Neurological Institute "C. Mondino" Foundation
Age-related Hearing Impairment, Personal Communication
Hearing Health Equity Through Accessible Research and Solutions for Korean Americans
The objective of this study is to test the effect of a community-delivered, affordable, and accessible hearing care intervention on improving communication function and health-related quality of life among older Korean Americans…
- Conditions
- Age-related Hearing Impairment, Personal Communication, Hearing Impairment, Hearing Loss
- Trial name
- K-HEARS (NCT06803394)
- Testing
- K-HEARS Intervention, K-HEARS Sound Amplifier Intervention
- Where
- United States
- Volunteers
- 800 people
- Sponsor
- Johns Hopkins University
Hypertension, High Blood Pressure
Home Blood Pressure Telemonitoring LINKED With Community Health Workers to Improve Blood Pressure
The LINKED-BP Program is a patient-centered, multi-level intervention linking home blood pressure monitoring (HBPM) with a telemonitoring platform (Sphygmo) that links with all Bluetooth-enabled validated blood pressure (BP)…
- Trial name
- LINKED-BP (NCT05180045)
- Testing
- LINKED-BP Program
- Where
- 20 sites in United States
- Volunteers
- 472 people
- Sponsor
- Johns Hopkins University
Dementia, Caregiver Burden
Comprehensive Home-based Dementia Care Coordination for Medicare-Medicaid Dual Eligibles in Maryland
This Center for Medicare and Medicaid funded health care innovation award will implement the MIND at Home dementia care coordination program (called MIND at Home-Plus) through two community-based service agencies (Jewish…
- Trial name
- NCT02395731
- Testing
- MIND at Home-Plus Intervention
- Where
- United States
- Volunteers
- 342 people
- Sponsor
- Johns Hopkins University
Aging
Effect of Dietary Supplementation on Dynamic Stability
The purpose of this study is to determine whether specific nutrient supplementation can improve dynamic stability in older adults.
- Trial name
- NCT02806765
- Testing
- (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol, Control
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University