Clinical trials: Comparative Study
Malaria in Pregnant HIV + Patients
A Comparative Study of Mefloquine and S-P as Prophylaxis Against Malaria in Pregnant HIV + Patients
Randomized controlled single blind prospective comparative study.
- Trial name
- NCT02524444
- Testing
- Mefloquine, Sulphadoxine-Pyrimethamine
- Where
- Nigeria
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- ORIYOMI OMOTOYOSI AKINYOTU
Healthy
Bioequivalence Study of Dr. Reddy's Laboratories Limited, Finasteride Tablets 1 mg Under Fasting Condition
The objective of this study was to compare the single-dose relative bioavailability of Dr. Reddy's Laboratories, Ltd. and Merck \& Co.
- Trial name
- NCT01133444
- Testing
- Finasteride
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
MEDICATION RELATED OSTEONECROSIS OF THE JAW
OZONE_EXO: Comparative Analysis of Protocols for Dental Exactions in Patients at Risk of MRONJ: Case-control Study
Medication-related osteonecrosis of the jaw (MRONJ) is a serious adverse reaction of antiresorptive and antiangiogenic agents; it is also a potentially painful and debilitating condition.
- Trial name
- OZONE_EXO (NCT06072404)
- Testing
- OxigenOzone_Insufflation
- Where
- Italy
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Multiple Sclerosis
BrainAgeMS - a Comparative Study of Brain Aging in Healthy and Patients With Multiple Sclerosis
The purpose of this study is to investigate new quantitative MRI-sequences for assessment of age-specific data for the prediction of brain aging.
- Trial name
- BrainAgeMS (NCT06221631)
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
COVID19, Sars-CoV2
Assessment of the Efficacy and Safety of (HCQ) as a Prophylaxis for COVID19 for Health Professionals
Assessment of the Efficacy and Safety of Hydroxychloroquine (HCQ) Administered as a Prophylaxis for Health Professionals Exposed to COVID19 and Working in Medical Intensive Care Units, in Tunisia.
- Conditions
- COVID19, Sars-CoV2, Hydroxychloroquine, Prophylaxis
- Trial name
- COVID_2Pro (NCT04349228)
- Testing
- Hydroxychloroquine (HCQ)
- Where
- Tunisia
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abderrahmane Mami Hospital
Missed Abortion
Comparative Study Between Combined Vaginal Misoprostol
"Comparative study between Combined Vaginal Misoprostol with Isosorbide-5-Mononitrate
- Trial name
- comparative (NCT04981457)
- Testing
- Misoprostol and iso sorbide mononitrates
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pharmacokinetics
Fasting Bioequivalence Study of 2 Metformin 500 mg Prolonged Release Tablets in 44 Healthy Male and Female Volunteers
This study was designed to compare the bioavailability of the Test Product Metformin 500mg Prolonged Release Tablets (JSC Farmak, Ukraine) and Reference Product Glucophage® XR 500 mg Prolonged Release Tablets (Merck Serono Ltd…
- Trial name
- NCT05124730
- Testing
- Metformin 500mg prolonged release tablets (JSC Farmak, Ukraine), Glucophage® XR 500 mg prolonged release tablets (Merck Serono Ltd, UK)
- Where
- Czechia
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Joint Stock Company "Farmak"
Dental Education and Special Care Dentistry
Comparison of Game-Based Learning and Model Arm Practice for Teaching Intravenous Cannulation to Dental Students
This randomized controlled study aimed to compare the effectiveness of game-based learning (GBL) and model arm practice in teaching peripheral intravenous cannulation (PIVC) skills to final-year dental students.
- Trial name
- NCT07060924
- Testing
- Game-Based Learning (GBL), Model Arm Practice
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Astigamtism
Prospective Comparative Study of Refractive Outcome of STAAR and Alcon Toric Intraocular Lenses
Several methods have been developed to address and reduce preexisting astigmatism. The refractive results associated with the use of toric IOLs are likely to be more predictable.
- Trial name
- NCT01121861
- Testing
- Phacoemulsification with implantation of toric IOL
- Where
- Singapore
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Diabetic Wound
A Comparative Study Between Vacuum Therapy Dressing and Conventional Dressing in Management of Diabetic Wounds
Diabetes is a global epidemic and a leading cause of death by disease. An estimated 366 million people worldwide had diabetes in 2011.(1).The incidence of diabetic foot ulcers (DFUs) and diabetic complications increases as the…
- Trial name
- NCT06153953
- Testing
- vacuum device, conventional dressing therapy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Diabetes Mellitus, Type 2
A Study to Compare the Effect of Giving Dulaglutide Using an Auto-injector Versus a Manual Syringe
The study involves 2 injections of 1.5 milligrams (mg) dulaglutide, 1 given by a pre-filled manual syringe, the other given by an auto-injector. Injections will be separated by a minimum 28-day washout period.
- Trial name
- NCT01524770
- Testing
- Dulaglutide
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Healthy, Renal Impairment
Comparative Study of Quinine Sulfate in Healthy Patients and in Patients With Renal Impairment
The effects of mild or moderate renal impairment (creatinine clearance 30 to 50 ml/min or >50 to 80 ml/min, respectively) on the pharmacokinetic profile of quinine and its active metabolite, 3'-hydroxyquinine, will be…
- Trial name
- NCT00785551
- Testing
- quinine sulfate
- Where
- United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Cystic Fibrosis, Bronchiectasis
Effect of HFCWO Vests on Spirometry Measurements
The impact of high-frequency chest wall oscillation therapy on spirometry values (Forced Expiratory Volume, Forced Vital Capacity, Peak Expiratory Flow, Forced Expiratory Flow and Tidal Volume is investigated during use of…
- Trial name
- NCT03628456
- Testing
- International Biophysics AffloVest, Hill-Rom Monarch
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- International Biophysics Corporation
Healthy
Comparative Bioavailability Study Between Etoricoxib and Tramadol, Administered Individually or in Combination
Study carried out in the Clinical and Analytical Unit of the Department of Pharmacology and Toxicology of the Faculty of Medicine of the Autonomous University of Nuevo León, with the objective of comparing the bioavailability…
- Trial name
- NCT05533073
- Testing
- A1: Etoricoxib / Tramadol Fixed dose combination, A2: Etoricoxib, A3: Tramadol
- Where
- Mexico
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Laboratorios Silanes S.A. de C.V.
Limb Edema, Surgical Site Infections
Prevention of Edema After Coronary Artery Bypass Graft by Customized Pressure-guided Elastic Bandages
The study aimed to assess the efficacy of customized pressure-guided elastic bandages (CPG-EB) in preventing postoperative edema and complications in Coronary Artery Bypass Graft (CABG) patients.
- Conditions
- Limb Edema, Surgical Site Infections, Leg Swelling, Compression Bandages
- Trial name
- PEACCE (NCT06603961)
- Testing
- CPG-EB group
- Where
- 2 sites in Thailand
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Diabetes Mellitus, Type 2
Comparison of the Bioavailability of Metformin Between Medium Dose Linagliptin/Metformin Tablets and Medium Dose Glucophage Tablet Given With Linagliptin Tablet
The data from this study will be used to compare the kinetic profile of metformin 500mg in linagliptin/metformin fixed dose combination tablet versus Canadian metformin reference product administered concomitantly with…
- Trial name
- NCT01383356
- Testing
- Metformin Single Tablet, Linagliptin/Metformin Combo, Linagliptin Single Tablet
- Where
- Canada
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Pharmacokinetics
Fasting Comparative Bioavailability Study of 2 Meloxicam 15 mg Tablets in Healthy Volunteers Under Fasting Condition
The aim of the study was to compare the bioavailability of two formulations of meloxicam given to healthy volunteers and to demonstrate bioequivalence.
- Trial name
- NCT05125588
- Testing
- Reumoxicam® 15 mg tablets (PJSC "Farmak", Ukraine), Movalis 15 mg tablets ("Boehringer Ingelheim Ellas A.E.", Greece)
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Joint Stock Company "Farmak"
Child Behavior, Life Skill Development
Improving School Climate and Children's Well-being Through the Life Skills "Feel Good" Intervention in French Schools: A Controlled Before-and-After Study
Life skills are major determinants of health that can be influenced through health promotion initiatives. Numerous educational interventions exist to foster the development of life skills.
- Conditions
- Child Behavior, Life Skill Development, School Health, School
- Trial name
- FEEL GOOD (NCT07804940)
- Testing
- FEEL GOOD
- Where
- France
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Université Paris Cité
Ovulation Inhibition
Ovulation Inhibition of Two 4-phasic Oral Contraceptive Regimens
The aim of the study is to investigate the ovulation inhibition of two 4-phasic oral contraceptive regimens.
- Trial name
- NCT00805415
- Testing
- EV/DNG (Qlaira, BAY86-5027, SH T00658K), EV/DNG (SH T00658L)
- Where
- 2 sites in Germany, Netherlands
- Volunteers
- 209 people, healthy volunteers welcome
- Sponsor
- Bayer
Smoking Cessation; Tobacco Dependence
Characterization of Smoking Habits Patterns in Medical Doctors of a Central Hospital in Portugal - What Has Changed After 15 Years? A Comparative Cross-sectional Study
Abstract: Tobacco dependence remains one of the primary health care concerns worldwide. Attitude of healthcare professionals towards smoking is crucial for any long-term prevention and smoking cessation program.
- Trial name
- NCT02913989
- Testing
- Smoking habits characterization
- Volunteers
- 423 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Ocidental
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