Clinical trials: Comparative Study
Local Tolerability After Lip Filler Injections
Safety and Efficacy of Lip Injections With Emervel Lips and Juvederm Ultra Smile
The purpose of this study is to demonstrate the efficacy and safety of Emervel Lips and Juvederm Ultra smile
- Trial name
- NCT01745250
- Testing
- Emervel Lips, Juvederm Ultra Smile
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Healthy Participants
A Research Study Looking Into Blood Levels of Three Different Formulations of the Study Medicine Ziltivekimab
A research study to investigate how quickly and to what extent different compositions of the study medicine ziltivekimab are absorbed, transported, and eliminated from the body. Ziltivekimab is not yet approved for market.
- Trial name
- NCT05721989
- Testing
- Ziltivekimab B, Ziltivekimab D, Ziltivekimab C
- Where
- 2 sites in Hungary, Netherlands
- Volunteers
- 267 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Stress
Effects of Dietary Supplements Based on Trace Elements on Voice Parameters and Some Psychological and Physiological Parameters Related to Stress - Single-center, Comparative, Cross-over, Randomized, Double-blind Study Versus Placebo, in Healthy Subjects
Preliminary data obtained by the company Pronutri, which produces food supplements based on trace metals, suggests that food supplements containing trace metal compounds could act by reducing stress, which could result in effects…
- Trial name
- NCT05313867
- Testing
- Nutri VX 1
- Where
- France
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Laboratoires Pronutri
Dental Caries
Clinical Evaluation of Different Resin Composite Restorations
Posterior resin composite is challenging esthetic restoration. Patients seek for durable, esthetic and functional restorations in molars. one of the major problems is polymerization shrinkage.
- Trial name
- NCT05418400
- Testing
- sonic fill 3 & PALFIQUE bulk flow & Neo spectra & Clear fill AP-X
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pharmacokinetics
A Comparative, Crossover, Pharmacokinetic, Pharmacodynamic and Safety Study of Three Forms of PEG-G-CSF in Normal Healthy Volunteers
This is a comparative pharmacokinetic, pharmacodynamic and safety study in healthy volunteers with three forms of pegylated granulocyte colony stimulating factors.
- Trial name
- NCT02205320
- Testing
- DRL_PG, Pegfilgrastim Form A, Pegfilgrastim Form B
- Where
- United States
- Volunteers
- 192 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
Bioequivalence Study of Topiramate Tablets 25mg Under Fasting Conditions
The objective of this study was to compare the single-dose relative bioavailability of Ranbaxy and Ortho-McNeil Pharmaceutical (Topamax®) 25 mg topiramate tablets following a 50 mg dose under fasting conditions.
- Trial name
- NCT00901784
- Testing
- Topiramate
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Colon Cancer, Colon Polyp
Comparison of Two Preparations for the Study of the Colon Through Colonoscopy
Compare the quality of bowel preparation between two groups of patients, who will undergo two different preparations: 1. Moviprep + diet; 2. Plenvu + diet
- Conditions
- Colon Cancer, Colon Polyp, Colon Adenoma, Colon Rectal Cancer
- Trial name
- NCT04497935
- Testing
- PLENVU, MoviPrep
- Where
- Portugal
- Volunteers
- 613 people, healthy volunteers welcome
- Sponsor
- Unidade Local de Saúde do Alto Ave, EPE
Diarrhea
Rifaximin Versus Placebo in the Prevention of Travelers' Diarrhea
The purpose of this study is to evaluate the effectiveness of poorly absorbed rifaximin in the prevention of travelers' diarrhea among U.S. college students in Mexico for five weeks.
- Trial name
- NCT00098384
- Testing
- rifaximin
- Where
- Mexico
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- DuPont, Hurbert L., MD
Healthy Volunteers
Povidone-iodine Against Sodium Hypochlorite as Skin Antiseptics
The investigators have few options for skin antisepsis. Alternatives for povidone-iodine, which is the most commonly used agent, are costly or ineffective. To have more options, this study is needed.
- Trial name
- NCT00738543
- Testing
- WHOLE GROUP OF 48 VOLUNTEERS
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Guanajuato
Dental Anxiety, Impacted Third Molar Tooth
Three Anxiolytic Drugs Used in Third Molar Surgery
This study was to compare the effectiveness of three drugs (Passiflora incarnata, Erythrina mulungum, Midazolam) in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT02065843
- Testing
- Mulungu, Passiflora incarnata, midazolam
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Upper Cervical Spine Rotational Hypomobility
Effects of Two Sub-occipital Techniques on Limited Mobility According to the Flexion-rotation Test
The cervical spine should work as a functional unit. If hypomobility should exist in any of the segments it would limit the mobility of the spine as a whole.
- Trial name
- NCT02855216
- Testing
- Manual technique of sub-occipital inhibition, Self-treatment by way of Occipivot®
- Where
- Spain
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Non-small Cell Lung Cancer
Clinical Trial in Chinese Healthy Volunteers of GB222
The primary objective of this study is to evaluate the similarity of the primary pharmacokinetic (PK) parameter AUC0-t of GB222 and bevacizumab after single administration; the secondary objective is to observe the safety and…
- Trial name
- NCT04175158
- Testing
- GB222, Bevacizumab
- Where
- China
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Genor Biopharma Co., Ltd.
Anxiety
Comparative Study of Hemodynamic Changes Caused by Diazepam and Midazolam During Third Molar Surgery
Objective: The aim of the present study was to compare hemodynamic changes using 7.5 mg of midazolam and 10.0 mg of diazepam during the surgical removal of symmetrically positioned third molars.
- Trial name
- NCT02177955
- Testing
- 7.5 mg Midazolam, 10 mg diazepam
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jimmy Barbalho
COVID-19
Study of the Tolerability, Safety, Immunogenicity and Preventive Efficacy of the EpiVacCorona Vaccine for the Prevention of COVID-19
The objective of the clinical study is to evaluate the tolerability, safety, immunogenicity and prophylactic efficacy of the EpiVacCorona vaccine in volunteers aged 18 and above.
- Trial name
- NCT04780035
- Testing
- EpiVacCorona (EpiVacCorona vaccine based on peptide antigens for the prevention of COVID-19)
- Where
- 8 sites in Russia
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector"
Epilepsy
Comparative Bioavailability Study of Two Different Sources of Eslicarbazepine Acetate
Phase I, two-centre, open-label, randomized, gender-balanced, single-dose, laboratory blinded, two-period, two-sequence, crossover study in 2 groups of 20 healthy male and female subjects, to demonstrate the bioequivalence (BE)…
- Trial name
- NCT02284880
- Testing
- BIA 2-093
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Hernias Inguinal Reducible, Local Anaesthesia
Comparison Between Desarda and Lichtenstein's Technique for Inguinal Hernia Repair Under Local Anaesthesia
Inguinal hernia repair is done by two methods. The conventional method uses a prosthetic mesh for strengthening the defect but has been associated with complications.
- Trial name
- NCT03512366
- Testing
- Desarda's technique, Lichtenstein's technique
- Where
- India
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- All India Institute of Medical Sciences, Bhubaneswar
Therapeutic Equivalency, Healthy
Fasted Bioavailability Study of Cilostazol Tablets, 50mg
The purpose of this study is to evaluate and compare the relative bioavailability of a test formulation of cilostazol tablets to an equivalent dose of Pletal® (cilostazol) tablets after a single oral dose administered under…
- Trial name
- NCT00685802
- Testing
- Cilostazol 50 mg Tablets, Cilostazol (Pletal®) 50 mg Tablets
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mutual Pharmaceutical Company, Inc.
Intraocular Pressure
Comparative Study of the NIDEK TONOREF III with Predicate Devices
The primary objective of this clinical study is to prove that tonometry values for NIDEK TONOREF III are comparable to the predicate device and to prove that the pachymeter function of NIDEK TONOREF III is equivalent to the…
- Trial name
- NCT06363045
- Testing
- NIDEK TONOREF III, Haag-Streit, PERKINS HAND-HELD APPLANATION TONOMETER, NIDEK CEM-530
- Where
- United Kingdom
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Nidek Co. LTD.
Pediatric Bladder Stones
Transurethral Versus Percutaneous Endoscopic Management of Bladder Stones in Boys
To compare safety and efficacy of trans urethral and per cutaneous approaches in endoscopic management of bladder stones in boys younger than 14 years
- Trial name
- NCT03294239
- Testing
- Transurethral extraction of bladder stone(s), percutaneous extraction of bladder stone(s)
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Healthy
Study to Determine the Equivalence of Two Products Containing Metronidazole Benzoate
The purpose of this study is to determine the bioequivalence of Metronidazole benzoate (400 mg metronidazole per sachet oral granules)/Terix Labs Ltd and Flagyl™ 400 mg Tablets (400 mg metronidazole per film coated…
- Trial name
- NCT02402283
- Testing
- Metronidazole benzoate oral granules, Flagyl 400 mg Tablets
- Where
- Jordan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Verisfield UK Ltd. Greek Branch
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