Clinical trials: Comparative Study
Healthy
Pharmacokinetic Comparison of XS003 and Tasigna
The study will assess bioavailability of XS003 given as a single oral dose compared to Tasigna® given as a single oral dose in healthy male subjects.
- Trial name
- NCT02068898
- Testing
- XS003, Tasigna
- Where
- United Kingdom
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- XSpray Microparticles
Healthy
Double Blind Randomized, Monocentric, Cross-over, Placebo-controlled Study to Evaluate the Effect of Morphine and Naloxone on Motivation (MBBAnalgesic)
The aim of the current study is to examine the role of the opioïd system on the cognitive parameters of motivation. They are embedded in a conceptual framework of motivation that merges decision-making and reinforcement learning…
- Trial name
- MBBAnalgesic (NCT02267304)
- Testing
- 50 mL of sodium chloride (0,9%), Morphine 0,05mg/kg, Naloxone 10mg
- Where
- France
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Healthy
A Pharmacokinetics Study Comparing PF-06438179 and Infliximab in Healthy Volunteers (REFLECTIONS B537-01)
In this study, healthy volunteers will receive a single intravenous dose of either PF-06438179 or infliximab (United States) or infliximab (European Union).
- Trial name
- NCT01844804
- Testing
- PF-06438179, Remicade
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Pfizer
Stone, Kidney, Stone Ureter
Virtual Reality for Pain Control During Extracorporeal Shock Wave Lithotripsy: a Prospective, Comparative, Randomized Study at a Single Institution
The aim of this study is to prospectively analyze patient satisfaction, pain, delivered energy and clinical effectiveness of using VR as a complimentary treatment modality during SWL.
- Trial name
- NCT05183269
- Testing
- Oncomfort virtual reality monitor (Oncomfort SA, Wavre, Belgium)
- Where
- Belgium
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- AZ Sint-Lucas Gent
Malaria, Pregnant
A Comparative Study of Azithromycin and S-P as Prophylaxis in Pregnant HIV+ Patients
Randomized controlled single blind prospective comparative study
- Conditions
- Malaria, Pregnant, HIV
- Trial name
- NCT02527005
- Testing
- Sulphadoxine-pyrimethamine, Azithromycin
- Where
- Nigeria
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Ibadan
Folliculitis Decalvans, Staphylococcus Aureus
Impact of Staphylococcus Aureus on Folliculitis Decalvans
The folliculitis decalvans (FD) is an orphan disease , common in consultation specialized on scalp. This disease is currently not curable, responsible for significant for patients.
- Trial name
- SAFE (NCT02157688)
- Testing
- no intervention : case control study
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Prostate Cancer
Comparative Study of Radiotherapy Treatments to Treat High Risk Prostate Cancer Patients
In North America, the number of new cases of prostate cancer increases every year. Many efforts have been made to develop more efficient and safer curative treatments for high risk prostate cancer patients.
- Trial name
- NCT02303327
- Testing
- EBRT + HDR brachytherapy boost, Hypofractionated Dose Escalation Radiotherapy, Androgen deprivation therapy
- Where
- 12 sites in Canada
- Volunteers
- 307 people, healthy volunteers welcome
- Sponsor
- Sir Mortimer B. Davis - Jewish General Hospital
Healthy
Study Of PF-06410293 And Adalimumab In Healthy Subjects (REFLECTIONS B538-01)
This healthy volunteers study will evaluate 210 subjects who will receive a single sub-cutaneous dose of PF-06410293 or adalimumab (United States) or adalimumab (European Union).
- Trial name
- NCT01870986
- Testing
- PF-06410293, Humira (adalimumab-EU), Humira (adalimumab-US)
- Where
- 2 sites in United States, Belgium
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Pfizer
Asthma, Chronic Obstructive Pulmonary Disease (COPD)
Bioequivalence Study of Synflutide HFA Inhaler and Seretide Evohaler in Healthy Volunteers With Charcoal Block
The objective of this pivotal study is to evaluate the relative bioavailability of Synflutide HFA 250/25 Inhaler and SeretideTM 250 EvohalerTM in healthy volunteers with charcoal block.
- Trial name
- NCT02466503
- Testing
- Fluticasone propionate, Salmeterol (as xinafoate)
- Where
- Taiwan
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Intech Biopharm Ltd.
Upper Gastrointestinal Endoscopy
Sedation for Upper Gastrointestinal Endoscopy in Pediatric Patients
The purpose of this study is to compere between Propofol-Ketamine combination and Dexmedetomidine-Ketamine combination for sedation in upper gastrointestinal endoscopy in paediatric patients.
- Trial name
- NCT02863861
- Testing
- Dexmedetomidine-ketamine, propofol-ketamine
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Healthy
Bioequivalence Study of Naproxen Sodium 550 mg Tablets Under Fasting Condition
An open label randomised, two-treatment, two-period, two-sequence, single-dose, crossover, comparative bioequivalence study.
- Trial name
- NCT01052129
- Testing
- Naproxen sodium
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Vaccine Reaction
Study on New Strategies for Hepatitis B Virus Immunization
To investigate the immunogenicity of HB vaccine with different series among primary immune adults aged 25-55, to assess potential alternative approaches for HB immunization.
- Trial name
- NCT06515938
- Testing
- 20μg Engerix-B hepatitis B vaccine, 20μg Kangtai hepatitis B vaccine, 60μg Kangtai hepatitis B vaccine
- Where
- 2 sites in China
- Volunteers
- 1,169 people, healthy volunteers welcome
- Sponsor
- Wu Jiang
Cardiac Arrhythmia
A Comparative Study of an Innovative 3-lead Wireless Water Resistant Holter System and a Conventional Holter System
Holter monitoring is one of the most widely used diagnostic methods to detect cardiac arrhythmias. Newer Holter monitors may provide some advantages over the more traditional ones.
- Trial name
- NCT04723355
- Testing
- An innovative 3-lead wireless water resistant Holter device, A conventional device
- Where
- Brazil
- Volunteers
- 231 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
HIV Infections, Measles
A Phase II, Comparative Study of Seroconversion of Single-Dose and Two-Dose Measles Vaccination in HIV-Infected and HIV-Uninfected Children: A Multicenter Trial of the Pediatric AIDS Clinical Trials Group
To compare measles seroconversion rates (development of antibodies) at 13 months of age in HIV-infected and uninfected children on one of two immunization schedules: attenuated measles/mumps/rubella virus (M-M-R II) vaccine at 12…
- Trial name
- NCT00000815
- Testing
- Attenuvax, M-M-R-II
- Where
- 46 sites in United States, Puerto Rico
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Myopia, Hyperopia
Complete Easy Rub Comparative Efficacy Study
The aim of this trial is to assess Complete Easy Rub compared to a competitor multi-purpose solution in terms of lens cleanliness, subjective response and ocular response, when lenses are worn bilaterally on a daily wear basis…
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01019564
- Testing
- Complete Easy Rub Formula MPS, Aquify MPS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Chronic Post Cesarean Pain
Comparative Study on the Effect of Quadratus Lumborum Block Versus Intrathecal Morphine on the Incidence of Chronic Pain Post Caesarean Section
The aim of this study is to compare the incidence of CPSCP in patients receiving QLB quadratus lumborum block and ITM versus control as a primary outcome and associated risk factors that might predispose patients to develop CPSCP.
- Trial name
- NCT05602038
- Testing
- Quadratus laborum block, Intrathecal morphine, intrathecal bupivacaine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Menoufia University
Healthy
A Bioequivalence Study Comparing Irbesartan/Atorvastatin Combination Tablet With Coadministration of Irbesartan and Atorvastatin
The purpose of this study is to evaluate pharmacokinetics and safety after oral administration of Irbesartan and Atorvastatin in combination as HCP0912
- Trial name
- NCT01447797
- Testing
- HCP0912 / Irbesartan and Atorvastatin
- Where
- South Korea
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Hanmi Pharmaceutical Company Limited
Occlusal Splints
Accuracy of Dental Contacts of an Occlusal Splint Made According to Conventional or Digital Techniques Using GeoMagic®.
To compare the accuracy of the occlusal splints made by conventional impression and milled with the splint made by intraoral scanner and milled.
- Trial name
- NCT05317182
- Testing
- Occlusal Splints Analogic-Analogic, Occlusal Splints Analogic-Digital, Occlusal Splints Digital-Digital
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Healthy
Bioequivalence Study of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg Tablets (Teva GmbH, Germany)
Comparative, Randomized, Single Dose, Two-way Crossover Bioequivalence Study to determine the bioequivalence of Modafinil From Bravamax 200 mg Scored Tablets (Chemipharm Pharmaceutical Industries, Egypt) Versus Vigil 200 mg…
- Trial name
- NCT05855187
- Testing
- Bravamax 200 mg (Modafinil), Vigil 200 mg (Modafinil)
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Genuine Research Center, Egypt
Healthy
A Pharmacokinetic Study of Gecacitinib Hydrochloride Tablets in Healthy Adult Participants.
This study will compare the pharmacokinetics (PK) effect of two different formulations of Gecacitinib Hydrochloride Tablets in healthy Adult participants
- Trial name
- NCT07565597
- Testing
- Gecacitinib Hydrochloride Tablets
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Suzhou Zelgen Biopharmaceuticals Co.,Ltd
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