Clinical trials: Comparative Study
Shigella Infection
Healthy Adult Volunteer Study for Two Doses of a Shigella Vaccine
The purpose of this study is to assess the immune response produced by two doses of SC599 vaccine compared to placebo.
- Trial name
- NCT00210288
- Testing
- SC599
- Where
- 2 sites in France, United Kingdom
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Institut Pasteur
Bioequivalence
Single Dose Crossover Comparative Bioavailability Study of Two Formulations of Fluconazole 200 mg in Healthy Adult Subjects Under Fasting Conditions
This single dose study is designed in accordance with EMA (the European Medicines Agency) regulatory guidelines, with the aim of characterizing the comparative bioavailability of fluconazole in the two formulations in healthy…
- Trial name
- NCT04038008
- Testing
- Fluconazole, Diflucan®
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Pharmtechnology LLC
Epilepsy, Bipolar Disorder
To Demonstrate the Relative Bioavailability of Divalproex Sodium 500 mg Delayed Release Tablets Under Fasting Conditions
To demonstrate the relative bioavailability of Divalproex Sodium 500 mg delayed release tablets under fasting conditions.
- Trial name
- NCT00913874
- Testing
- Divalproex Sodium 500 mg DR Tablets (Sandoz Inc., USA), Depakote 500 mg DR Tablets (Abbott Laboratories, USA)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sandoz
Healthy
Bioequivalence Study of FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET in Healthy Subjects Under Fasting Conditions
To assess the bioequivalence of Test oral formulation of FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET versus Reference ANTADYS®100 mg Comprimé Pelliculé \& PEPCID® (Famotidine) 20mg Tablets, USP.
- Trial name
- NCT01910090
- Testing
- FLURBIPROFEN 100 mg FAMOTIDINE 20 mg MULTI-LAYER TABLET, ANTADYS® 100 mg, PEPCID® 20 mg
- Where
- Jordan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Pharmaceutical Research Unit, Jordan
Diabetes Mellitus
Comparative Wockhardt's Glucose Clamp Study-Human Isophane Susp 30IU/ml/70IU/ml With Novolin70/30, in Healthy Subjects
The aim of this trial is to demonstrate bioequivalence of Wosulin 70/30 to Novolin® 70/30 with regard to its total and to its maximum serum insulin concentrations.
- Trial name
- NCT01358435
- Testing
- 30% Regular Insulin Human Neutral and 70%Isophane Insulin, Novolin 70/30
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Wockhardt
Class II Malocclusion
Conventional Versus 3D Printed Twin Block Appliances in Growth Modification of Class II Malocclusion
The present study was conducted to evaluate the outcomes of conventionl versus 3D printed twin block appliances in growth modification of class II malocclusion (comparative clinical study) in both groups.
- Trial name
- RCT (NCT07792525)
- Testing
- Twin Block
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Femoro-acetabular Impingement
Hip Muscle Strength in FAI Versus Normal Controls
Hip Muscle Strength in femoro-acetabular impingement participants versus normal controls. To investigate the hip muscle strength in a normal control group and compare this to patients who have a diagnosis of femoro-acetabular…
- Trial name
- NCT02697097
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Cervical Pain, Postural Balance
Balance Performance in Dual Task in Patients With Cervical Disc Herniation Related Chronic Neck Pain:a Comparative Study
Intense pain and moderate disability are seen most patients with symptomatic cervical disc herniation (CDH). Since neck motion and motor control are associated with changes in neck pain and disability, it is highly likely that…
- Trial name
- NCT05338788
- Testing
- neck pain and dual task
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Bozyaka Training and Research Hospital
Major Depressive Disorder
Comparative Study of Physiological and Cerebrovascular Reactivity in Depression, at the Three Phases of Emotion
The main objective is to compare the physiological reactivity (heart and respiratory rates, galvanic skin response, cerebral perfusion, and startle) in the three phases of emotion between depressive subjects, subjects remitted…
- Trial name
- EMPHILINE (NCT02026622)
- Testing
- psychometric tests, MRI, transcranial doppler and TPI
- Where
- France
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Vertical Alveolar Bone Loss, Sinus Lifting
Use of Specifically Designed Drills for Internal Sinus Lifting
This study was conducted at Ege University, School of Dentistry, Izmir, Turkey. Patients enrolled require implant placement to the atrophic posterior maxilla.
- Conditions
- Vertical Alveolar Bone Loss, Sinus Lifting, Implant Therapy
- Trial name
- NCT06640127
- Testing
- Sinus lifting and implant placement with osteotomes, Sinus lifting and implant placement with specifically designed drills
- Where
- Turkey (Türkiye)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ege University
Sunburn
Efficacy and Safety of Diclofenac Sodium (0.1%) Gel in Patients With UV Induced Painful Sunburn
Diclofenac sodium 0.1% will be applied to sunburned skin when the intensity of pain reaches a certain level in order to evaluate the efficacy and safety of the treatment on this induced pain.
- Trial name
- NCT00441051
- Testing
- Diclofenac sodium 1mg/g
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Novartis
Postoperative Nausea and Vomiting
Post-operative Nausea Vomiting in Laparoscopic Cholecystectomy
To study the efficacy and side effects of ondansetron with dexamethasone in patients undergoing standard laparoscopic cholecystectomy (control group).
- Trial name
- PONV (NCT02803788)
- Testing
- ramosetron, ondansetron, dexamethasone
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Government Medical College, Haldwani
Cholera
A Phase III Randomized, Modified Double-blind, Multi-centric, Comparative Study, to Evaluate the Non-inferiority of Immunogenicity and Safety of Hillchol® (BBV131)to Shanchol™ Along With Lot-to-lot Consistency of Hillchol®(BBV131).
A Phase III randomized, modified double-blind, multi-centric, comparative study, to evaluate the noninferiority of immunogenicity and safety of single strain oral cholera vaccine Hillchol® (BBV131) to the comparator vaccine…
- Trial name
- Hillchol (NCT05507229)
- Testing
- Hillchol vaccine, Shanchol Vaccine
- Where
- 11 sites in India
- Volunteers
- 1,800 people, healthy volunteers welcome
- Sponsor
- Bharat Biotech International Limited
Parkinson's Disease (PD), Healthy Control Subjects
This Protocol is a Sub-study Under the PPMI Program. It is a Longitudinal, Single-center Study to Assess the Performance of [18F]AV-133 Imaging Using High and Standard Resolution PET in Individuals Enrolled With Parkinson's Disease (PD) for up to 12 Months.
The study is a longitudinal, single-center study to assess progression of [18F]AV-133 imaging in PD participants. Participants will be followed for up to 12 months.
- Trial name
- NCT07830654
- Testing
- [18F]AV-133
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Michael J. Fox Foundation for Parkinson's Research
To Determine Bioequivalence Under Fed Conditions
A Comparative Bioavailability Study of Lisinopril Tablets, 40 mg - Effect of Food Study
The purpose of this study is to compare the bioavailability of Par Lisinopril 40 mg Tablets and IPR Pharmaceuticals, Inc. Zestril (R).
- Trial name
- NCT01380431
- Testing
- Lisinopril
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Par Pharmaceutical, Inc.
Warts
Clinical Study : Efficacy and Safety of Three Cryotherapy Devices for Wart Treatment
The present study was set-up to evaluate clinical efficacy of Pixie® cryogenic pen versus two comparator cryogenic products (Wartner® and Wortie®) for the treatment of common and plantar warts.
- Trial name
- NCT03129373
- Testing
- Cryogenic treatment of warts
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Oystershell NV
This Study is to Evaluate the Prevalence, Patients Consulting the Emergency Department for Reasons Relating to General Medicine
Patient Care Pathway and Factors Influencing Their Choice to Consult in the Emergency Department or an Out-of-Hours Care Service: A Comparative Study
It focuses on the patient care pathway and the factors influencing their choice to seek consultation in the Emergency Department or Out-of-Hours Care Service for issues that fall under general medicine.
- Trial name
- PSP-FICU (NCT07046754)
- Testing
- type of consultation
- Where
- 2 sites in France
- Volunteers
- 194 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Martigues
Healthy Volunteers
Study Comparing TPI-120 and Neulasta Administered Through Subcutaneous Route in Healthy Adult Subjects
This is a single or up to 2 centers, double-blind, randomized, single-dose, two-way, crossover study comparing the Test (T) and Reference (R) products following subcutaneous administration.
- Trial name
- TPI-120 (NCT03206229)
- Testing
- PEG-rhG-CSF, Neulasta (PEG-rhG-CSF)
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Adello Biologics, LLC
Post Operative Nausea and Vomiting
Mirtazapine Versus Dexamethasone in Preventing Postoperative Nausea and Vomiting
Mirtazapine is a noradrenergic and specific serotonergic antidepressant. Its antagonist at the 5HT3 receptor may help to prevent nausea and vomiting.
- Trial name
- NCT04547842
- Testing
- Mirtazapine 30 MG, Dexamethasone
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Intrabony Periodontal Defect
Efficacy of Titanium Granules in the Treatment of Periodontal Intrabony Defects
The ideal goal of the periodontal treatment is not only to prevent the progression of the disease, but also the regeneration and reconstruction of lost tissues.
- Trial name
- NCT04932161
- Testing
- Titanium Granules, Hydroxyapatite
- Where
- India
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- SVS Institute of Dental Sciences
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