Clinical trials: Comparison of the Efficacy
Pulmonary Disease, Chronic Obstructive
Safety and Efficacy of Two Different Doses of Ipratropium Bromide Versus ATROVENT® Inhalation Aerosol in Adults With Chronic Obstructive Pulmonary Disease
The objective of this study is to confirm that chronic dosing of 20 mcg and 40 mcg of ipratropium bromide, administered via the RESPIMAT device, demonstrates clinical comparability and similar safety profiles to the 36 mcg dose…
- Trial name
- NCT02177344
- Testing
- Low dose of Ipratropium bromide, High dose of Ipratropium bromide, Atrovent
- Volunteers
- 646 people
- Sponsor
- Boehringer Ingelheim
Non-Small Cell Lung Cancer
A Randomized Phase 2 Study of Atezolizumab (an Engineered Anti-PDL1 Antibody) Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum Therapy - "POPLAR"
This multicenter, open-label, randomized study will evaluate the efficacy and safety of Atezolizumab compared with docetaxel in participants with advanced or metastatic non-small cell lung cancer after platinum failure.
- Trial name
- NCT01903993
- Testing
- Docetaxel, Atezolizumab
- Where
- 65 sites in United States, Belgium and 11 more
- Volunteers
- 287 people
- Sponsor
- Hoffmann-La Roche
Smoking Cessation
Comparison of Efficacy and Safety of Rimonabant 5mg/Day or 20mg/Day Versus Placebo in Smoking Cessation
The primary objective is to assess the efficacy of 2 fixed doses of rimonabant versus placebo on abstinence from tobacco use in cigarette smokers.
- Trial name
- STRATUS-EU (NCT00464165)
- Testing
- rimonabant
- Where
- 7 sites in Belgium, Denmark and 5 more
- Volunteers
- 789 people
- Sponsor
- Sanofi
Insomnia
A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia
This is a multi center, double blind placebo controlled, two-way crossover study in patients with Insomnia suffering from difficulty in falling asleep and staying asleep.
- Trial name
- NCT01277107
- Testing
- Zaleplon AP formulation
- Where
- 6 sites in United States, Israel
- Volunteers
- 83 people
- Sponsor
- Intec Pharma Ltd.
Coronary Artery Disease(CAD)
Comparison of Diagnostic Accuracy Between XTR004 PET MPI and the Composite Index of Quantitative Coronary Angiography (QCA) and Fractional Flow Reserve (FFR)
The primary objective of this study is to evaluate the effectiveness of visual reading in XTR004 PET myocardial perfusion imaging (MPI) for detecting restrictive stenosis, using quantitative coronary angiography (QCA) and…
- Trial name
- NCT07439133
- Testing
- XTR004
- Where
- 5 sites in China
- Volunteers
- 395 people
- Sponsor
- Sinotau Pharmaceutical Group
Hypertriglyceridemia, Hyperlipoproteinemia Type IV
A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides
The Torcetrapib project was terminated on December 2, 2006 due to safety findings. To assess the safety and efficacy of the fixed combination torcetrapib/atorvastatin in subjects with Fredrickson Type IV Hypertriglyceridemia.
- Trial name
- NCT00134498
- Testing
- torcetrapib/atorvastatin, atorvastatin
- Where
- 44 sites in United States, Canada
- Volunteers
- 160 people
- Sponsor
- Pfizer
Gastric Ulcers, Duodenal Ulcers
Efficacy and Safety of TAK-438 for the Prevention of Recurrent Gastric or Duodenal Ulcers During Therapy of Low-dose Aspirin
The purpose of this study is to evaluate the efficacy of TAK-438, once daily (QD) compared to AG-1749 (Lansoprazole) in patients with a history of gastric or duodenal ulcer who require long-term therapy of low-dose aspirin.
- Trial name
- NCT01452763
- Testing
- TAK-438, Lansoprazole
- Where
- 76 sites in Japan
- Volunteers
- 621 people
- Sponsor
- Takeda
White Spot Lesion
Comparison of Remineralisation Efficacy of MI PASTE Plus® and REMIN PRO® for White Spot Lesions in Primary Teeth
The present study aimed to compare the remineralisation capacity of white spot enamel lesions between two commercially available tooth pastes (Remin Pro and MI PASTE PLUS), applied at home twice a day on the anterior upper…
- Trial name
- NCT04382287
- Testing
- Remin Pro® and MI Paste Plus®
- Where
- Mexico
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de San Luis Potosí
Chronic Idiopathic Urticaria, Urticaria
The Efficacy and Safety of Desloratadine With Levocetirizine in Treatment of Chronic Idiopathic Urticaria
Objective: To compare the efficacy of desloratadine 5mg (Denosin®) and levocetirizine 5mg (Xyzal®) once daily in the treatment of patients with CIU over 6 weeks.
- Trial name
- NCT00346606
- Testing
- Denosin® and Xyzal®
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Lotus Pharmaceutical
Chronic Tinnitus, Subjective Tinnitus
tVNS and Myofascial Release in Tinnitus
This randomized controlled trial aims to investigate the effectiveness of transcutaneous vagus nerve stimulation (tVNS) and myofascial release exercises in patient wiht chronic subjective tinnitus.
- Conditions
- Chronic Tinnitus, Subjective Tinnitus, Neuromodulation
- Trial name
- TVNS-TINN (NCT07155733)
- Testing
- Transcutaneous Vagus Nerve Stimulation, Myofascial Release Exercises, Standard medical treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Necmettin Erbakan University
Whitening
Clinical Study to Evaluate the Tooth Whitening Efficacy
Optic White 5%HP ActivShine TP vs Crest3D White TP (head-to-head whitening clinical) The objective of this study is to evaluate the tooth whitening efficacy of a Colgate toothpaste with 5% Hydrogen Peroxide and Fluoride compared…
- Trial name
- NCT06957249
- Testing
- Optic White 5%HP ActivShine Toothpaste, Crest3DWhite Advanced Radiant Mint Toothpaste
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Anxiety
Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Anxiety: A Randomized Clinical Trial
The present study will be conducted at the Department of Physiology in collaboration with the Department of Psychiatry of R.D. Gardi Medical College, Ujjain, Madhya Pradesh.
- Trial name
- NCT05845658
- Testing
- Active VeNS
- Where
- India
- Volunteers
- 60 people
- Sponsor
- Neurovalens Ltd.
HIV Infections
VERxVE Study on Efficacy and Safety of Nevirapine XR in Comparison to Nevirapine IR With Truvada in Naive HIV+ Patients
The primary objective of this study is to evaluate the efficacy of 400 mg QD nevirapine extended release (NVP XR) formulation versus 200 mg BID nevirapine immediate release (NVP IR) in ARV therapy naïve HIV-1 infected patients…
- Trial name
- NCT00561925
- Testing
- nevirapine IR, nevirapine XR
- Where
- 202 sites in United States, Argentina and 19 more
- Volunteers
- 1,068 people
- Sponsor
- Boehringer Ingelheim
Type 2 Diabetes
A Phase 3 Study to Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus
This is a multicenter, randomized, double-blind, active-controlled, parallel-group study, which aims to provide data on the efficacy and safety of HDM1002 tablets compared with dapagliflozin in adults with type 2 diabetes…
- Trial name
- NCT07082114
- Testing
- HDM1002 100 mg, HDM1002 200 mg, HDM1002 400 mg
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.
Type 2 Diabetes Mellitus
Study of Muraglitazar Versus Pioglitazone in Type 2 Diabetes
The purpose of this study is to compare Muraglitazar and Pioglitazone in patients with Type 2 Diabetes. Both the safety and blood sugar lowering effects of these treatments will be studied.
- Trial name
- NCT00106808
- Testing
- Muraglitazar, Pioglitazone
- Where
- 195 sites in United States, Argentina and 12 more
- Volunteers
- 1,440 people
- Sponsor
- Bristol-Myers Squibb
Subacromial Impingement Syndrome
Comparison of Supervised Rehabilitation and Home Exercise Programs in Subacromial Impingement Syndrome
This randomized controlled trial aims to compare the effectiveness of physiotherapist-supervised rehabilitation and home exercise programs in individuals with subacromial impingement syndrome (SAIS).
- Trial name
- SAIS-REHAB (NCT07568340)
- Testing
- Supervised Rehabilitation Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Urinary Bladder, Overactive
The Efficacy of Intravaginal Electrical Stimulation in Women With Idiopathic Overactive Bladder
In this study, it was aimed to compare the effectiveness of intravaginal electrical stimulation (IVES) added to bladder training (BT) on quality of life (QoL) and clinical parameters related to overactive bladder (OAB) in…
- Trial name
- NCT05416450
- Testing
- intravaginal electrical stimulation added to bladder training
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Pamukkale University
Overactive Bladder, Benign Prostatic Hyperplasia
Combination Treatment With Doxazosin Plus TolterodineSR 2 mg Versus 4mg in Men With an Overactive Bladder (OAB) and Benign Prostatic Hyperplasia (BPH)
OAB occurs in approximately 50% to 75% of men with BPO and up to 38% of men with BPO continue to suffer from OAB after relief the obstruction.Symptoms of OAB are more bothersome than the voiding complaints of slow stream and…
- Trial name
- NCT00922506
- Testing
- doxazosin plus tolterodine SR
- Where
- South Korea
- Volunteers
- 83 people
- Sponsor
- Samsung Medical Center
COPD Patients
Comparing the Efficacy of Symbicort® pMDI and Formoterol Turbuhaler in Reducing Exacerbations in Patients With Cronic Obstructive Pulmonary Disease
Comparing the efficacy of Symbicort® pMDI and Formoterol Turbuhaler in reducing exacerbations in patients with Chronic Obstructive Pulmonary Disease (COPD).
- Trial name
- RISE (NCT02157935)
- Testing
- Symbicort, Formoterol turbohaler
- Where
- 371 sites in United States, Argentina and 9 more
- Volunteers
- 2,026 people
- Sponsor
- AstraZeneca
De Quervain's Tenosynovitis
Analyze the Comparison of the Effectiveness of Kinesio ®and Dynamic Taping for De Quervain's Tenosynovitis
_De Quervain's tenosynovitis is inflammation and swelling of the tendon caused by repetitive thumb movements. In severe cases, the tendon sliding is limited, resulting in limited joint range of motion and affecting the quality of…
- Trial name
- NCT07062276
- Testing
- Dynamic taping, Kinesio ®
- Where
- Taiwan
- Volunteers
- 8 people
- Sponsor
- Taipei Medical University Shuang Ho Hospital
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