Clinical trials: Comparison of the Efficacy
Adult Non-trauma Cardiac Arrest Resuscitation, Effectiveness of In-situ Simulation (ISS) Training
Effectiveness of In-Situ Simulation Training in Adult Non-Trauma Resuscitation: A Comparison of ISS and OSS Team Performance Using the A-C-L-S Model
This study employed a two-group non-randomized pre-post design to evaluate the effectiveness of interprofessional ISS training over one year at the National Taiwan University Hospital Yunlin Branch.
- Conditions
- Adult Non-trauma Cardiac Arrest Resuscitation, Effectiveness of In-situ Simulation (ISS) Training, Effectiveness of Off-site Simulation (OSS) Training, Improvement of Teamwork in Emergency Care Settings
- Trial name
- NCT07358793
- Testing
- In-situ Simulation (ISS) Training, Off-site Simulation (OSS) Training
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Gingivitis
Miswak Efficacy Compared With Chlorhexidine
Gingivitis is a form of gum disease and is elicited by the accumulation of plaque on the tooth and the soft-tissue adjoining the tooth.
- Trial name
- MiswakChlorx (NCT04607785)
- Testing
- Miswak mouthwash group, Chlorhexidine gluconate mouthwash
- Where
- Iraq
- Volunteers
- 60 people
- Sponsor
- Al-Iraqia University
Mother-Child Relations, Substance Use
Optimizing Mental Health for Infants Exposed to Early Adversity: A Comparison of Breaking the Cycle and Maxxine Wright
The goal of this clinical trial is to compare the effectiveness of the Breaking the Cycle (BTC) and Maxxine Wright (MW) programs in substance-involved mothers and their children.
- Trial name
- NCT05768815
- Testing
- Breaking the Cycle Program, Maxxine Wright Program
- Where
- 2 sites in Canada
- Volunteers
- 100 people
- Sponsor
- University of Ottawa
Skin Ulcer, Burns
Effectiveness Comparison of Skin Micro-grafts vs Meshed Split Thickness Skin Grafts
This is a double-blind randomized controlled clinical trial, that compares the percentage of epithelialization of skin defects using the conventional meshed split thickness skin grafts vs skin micro grafts.
- Trial name
- NCT02813213
- Testing
- Skin micro Grafts, Standard skin graft
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Onchocerciasis
Efficacy of Ivermectin and Albendazole Against Onchocerciasis in the Volta Region, Ghana
We will examine whether a combination of Ivermectim (IVM) plus Albendazole (ALB) compared to IVM alone given annually, which is the current standard for mass drug administration (MDA), is more effective in sterilizing adult…
- Trial name
- NCT02078024
- Testing
- IVM plus ALB, IVM
- Where
- Ghana
- Volunteers
- 375 people
- Sponsor
- University Hospitals Cleveland Medical Center
Non Proliferative Diabetic Retinopathy
Study to Evaluate Efficacy and Safety of Entelon 50mg in Patients With Non-Proliferative Diabetic Retinopathy
This clinical trial is a multi-center, double-blind, randomized, placebo controlled , parallel design, superiority, phase 4 study to evaluate the efficacy and safety of Entelon 50mg in 396 patients with non-proliferative diabetic…
- Trial name
- NCT05358080
- Testing
- Entelon Tab. 50mg
- Where
- South Korea
- Volunteers
- 396 people
- Sponsor
- Hanlim Pharm. Co., Ltd.
Subjective Tinnitus
Efficacy, Safety and Tolerability of Neramexane in Comparison to Placebo in Patients With Subjective Tinnitus
The purpose of this study is to investigate the safety and efficacy of neramexane mesylate in the treatment of subjective tinnitus in comparison to placebo.
- Trial name
- NCT00772980
- Testing
- Neramexane mesylate
- Where
- 56 sites in Belgium, Czechia and 4 more
- Volunteers
- 400 people
- Sponsor
- Merz Pharmaceuticals GmbH
Breast Cancer, Hypercalcemia of Malignancy
Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone
RATIONALE: Zoledronic acid may help decrease the risk of broken bones, bone pain, and other symptoms caused by bone metastases. It may also help patients live more comfortably.
- Conditions
- Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, Musculoskeletal Complications
- Trial name
- NCT00458796
- Testing
- zoledronic acid, quality-of-life assessment
- Where
- 30 sites in United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- University of Leeds
Systemic Sclerosis
A Study to Compare the Efficacy and Safety of BMS-986353 (Zolacabtagene- Autoleucel / Zola-cel), CD19-CAR T Cells, Versus Standard of Care in Participants With Active Systemic Sclerosis
The purpose of this study is to compare the efficacy and safety of BMS-986353 versus standard of care in participants with active Systemic Sclerosis
- Trial name
- Breakfree-SSc (NCT07335562)
- Testing
- BMS-986353, Fludarabine, Cyclophosphamide
- Where
- 56 sites in United States, Belgium and 8 more
- Volunteers
- 92 people
- Sponsor
- Juno Therapeutics, Inc., a Bristol-Myers Squibb Company
Cystic Fibrosis
Study to Evaluate the Safety and Efficacy of Ciprofloxacin (Inhaled) in Patients With Cystic Fibrosis
To evaluate the change in forced expiratory volume (FEV1) from baseline to Day 28-30 between Cipro Inhale-treated and placebo-treated subjects after a 4-week treatment period.
- Trial name
- NCT00645788
- Testing
- Ciprofloxacin (Cipro Inhale, BAYQ3939)
- Where
- 86 sites in United States, Australia and 7 more
- Volunteers
- 288 people
- Sponsor
- Bayer
Extensive-stage Small Cell Lung Cancer
Study of Anlotinib as the Maintenance Therapy for Extensive-stage Small Cell Lung Cancer
Anlotinib has been approved as a third-line treatment for advanced non-small-cell lung cancer. A phase II clinical studies of small cell lung cancer (ALTER-1210) also showed that, compared with placebo, Anlotinib could improve…
- Trial name
- NCT03781869
- Testing
- Anlotinib Hydrochloride; etoposide and cisplatin, etoposide and cisplatin
- Volunteers
- 116 people
- Sponsor
- Third Military Medical University
Reflux Esophagitis
An Efficacy Study to Compare the Treatment Effects of Rabeprazole and Lansoprazole Depending on the Genotyping of CYP2C19 in Treating Reflux Esophagitis
The purpose of this study is to compare the treatment effects of rabeprazole and lansoprazole depending on the genotyping (process of determining the genetic constitution) of CYP2C19 in treating reflux esophagitis (caused by…
- Trial name
- NCT01008696
- Testing
- Rabeprazole, Lansoprazole
- Volunteers
- 217 people
- Sponsor
- Janssen Korea, Ltd., Korea
Breast Cancer, Early Detection of Cancer
A Prospective Study to Evaluate Clinical Performance of Thermalytix in Detecting Breast Cancers
The purpose of this study is to determine the clinical performance of AI-based Thermalytix with the current standard-of-care diagnostic modalities in women.
- Trial name
- NCT04688086
- Testing
- Thermalytix
- Where
- India
- Volunteers
- 687 people, healthy volunteers welcome
- Sponsor
- Niramai Health Analytix Private Limited
Facial Paralysis
A Study of NTX-001 in the Treatment and Prevention of Facial Paralysis Requiring Surgical Repair.
This study involves the use of an Investigational Product called NTX-001. It is a product used in the repair of nerve injuries. It is used in the operating room.
- Trial name
- NCT05293522
- Testing
- NTX-001
- Where
- 6 sites in United States
- Volunteers
- 2 people
- Sponsor
- Neuraptive Therapeutics Inc.
Malignant Pleural Effusion
A Study to Compare the Efficacy and Safety of Intrapleural Doxycycline Versus Iodopovidone for Performing Pleurodesis in Malignant Pleural Effusion
Malignant pleural effusion (MPE) arises in advanced-stages of malignancies and frequently heralds a poor prognosis.If the underlying malignancy is chemo sensitive (e.g., small-cell carcinoma of lung \& lymphoma), systemic…
- Trial name
- NCT02583282
- Testing
- Doxycycline, Iodopovidine
- Where
- India
- Volunteers
- 100 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Asthma
A 12-Week Study in Asthmatic Children Ages 6 to <12 Years, Investigating the Efficacy and Safety of Symbicort pMDI 80/2.25 μg and Symbicort pMDI 80/4.5 μg, Compared With Budesonide pMDI 80 μg
The purpose is to investigate the Efficacy and Safety of Symbicort pMDI 80/2.25 μg and Symbicort pMDI 80/4.5 μg, Compared with Budesonide pMDI 80 μg, 2 Actuations Twice Daily, in Children Ages 6 to <12 Years with Asthma during 12…
- Trial name
- CHASE 3 (NCT02091986)
- Testing
- Symbicort pMDI, Budesonide pMDI
- Where
- 70 sites in United States, Mexico and 2 more
- Volunteers
- 882 people
- Sponsor
- AstraZeneca
Osteoporosis, Osteopenia
A Randomized, Double-Blind Study to Compare the Efficacy of Treatment With Denosumab Versus Alendronate Sodium in Postmenopausal Women With Low Bone Mineral Density.
The purpose of this study is to determine whether in postmenopausal women with low bone mineral density, the mean percent change in total hip BMD in subjects receiving denosumab is not less than that observed in subjects…
- Trial name
- NCT00330460
- Testing
- Alendronate, Denosumab
- Volunteers
- 1,189 people
- Sponsor
- Amgen
Cerebrospinal Fluid Leak
The EVICEL® Neurosurgery Phase III Study
The objective of this study is to evaluate the safety and efficacy of EVICEL® Fibrin Sealant (Human) for use as an adjunct to sutured dural repair in cranial surgery.
- Trial name
- NCT02457546
- Testing
- EVICEL Fibrin Sealant, Hydrogel sealant
- Where
- 26 sites in United States, Australia and 4 more
- Volunteers
- 234 people
- Sponsor
- Ethicon, Inc.
Diabetes Mellitus
Safety and Efficacy Study of Alogliptin on Glycemic Control in Subjects With Type 2 Diabetes.
The purpose of this study is to determine the safety and efficacy of alogliptin, once daily (QD), compared to diet and exercise, sulfonylurea, metformin and a combination of sulfonylurea and metformin for treating subjects with…
- Trial name
- NCT00755846
- Testing
- Alogliptin
- Volunteers
- 265 people
- Sponsor
- Takeda
Hip Fracture, Pain Management
Comparison of the Efficacy of Ultrasound-guided Supra-inguinal Fascia Iliaca and Lumbar Erector Spina Plan Block in Hip Fractures
The aim of our study was to evaluate the efficacy and patient satisfaction level of SI-FIB and lumbar ESPB for positioning and postoperative analgesia during spinal anesthesia in patients undergoing hip fracture surgery.
- Conditions
- Hip Fracture, Pain Management, Multimodal Analgesia, Peripheral Nerve Block
- Trial name
- NCT07639762
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
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