Clinical trials: Compartment Syndrome
Acute Compartment Syndrome
The Research About Acute Compartment Syndrome
Acute compartment syndrome (ACS) is defined as a clinical entity originated from trauma or other conditions, and remains challenging to diagnose and treat effectively. Threre is the controversy in diagnosing, treating ACS.
- Trial name
- NCT04529330
- Testing
- fasciotomy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Hebei Medical University Third Hospital
Critically Ill, Intra-Abdominal Hypertension
The Influence of Fluid Removal Using Continuous Venovenous Hemofiltration (CVVH) on Intra-abdominal Pressure and Kidney Function
Intra- abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are a cause of organ dysfunction in critically ill patients.
- Conditions
- Critically Ill, Intra-Abdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury
- Trial name
- NCT01077895
- Testing
- CVVH, ultrafiltration, ultrafiltration control group
- Where
- 2 sites in Belgium
- Sponsor
- University Hospital, Ghent
Intra-Abdominal Hypertension, Abdominal Compartment Syndrome
Surveillance, Prevention and Treatment of Intra-abdominal Hypertension and Abdominal Compartment Syndrome
This study evaluates the efficacy of intensive surveillance, prevention and treatment of intra-abdominal hypertension in ICU patients. In the first two months patients will be screened and undergo usual care.
- Trial name
- NCT03876418
- Testing
- Intra-abdominal Pressure
- Volunteers
- 750 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hernia, Ventral, Hernia Incisional
Renal- and Pulmonary Function in Relation to Abdominal Hypertension After Abdominal Reconstruction
An incisional hernia is technically challenging to operate and is the most frequent long-term complication after open surgery, resulting in impaired quality of life and reduced physical ability.
- Conditions
- Hernia, Ventral, Hernia Incisional, Acute Kidney Injury, Restrictive Lung Disease
- Trial name
- REPARE (NCT04143776)
- Testing
- Abdominal reconstruction
- Where
- Denmark
- Sponsor
- Bispebjerg Hospital
Muscle Oxygenation, Skin Pigmentation
Muscle Oxygenation and Skin Pigmentation
The investigators plan to enroll 500 consecutive Subjects at a major trauma center for this study. For each patient, the body mass index (BMI), age, sex, diastolic pressure and mean arterial pressure (MAP) at time of…
- Trial name
- NCT00747162
- Testing
- Measure of muscle oxygenation, Skin pigmentation determination
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Intra-Abdominal Hypertension, Venous Congestion
Correlation of Ultrasonography Indices of Venous Congestion With Intra-abdominal Pressure in ICU Patients.
The goal of this prospective observational study is to examine the potential association between intra-abdominal pressure and venous congestion as assessed by abdominal ultrasound, in critically ill patients in the Intensive Care…
- Trial name
- NCT06160856
- Testing
- Abdominal ultrasound
- Volunteers
- 84 people
- Sponsor
- National and Kapodistrian University of Athens
Acute Pancreatitis, Intra-abdominal Hypertension
The Correlations Between Early Enteral Nutrition and Intra-abdominal Pressure in Severe Acute Pancreatitis
As an important management of severe acute pancreatitis (SAP), enteral nutrition (EN), especially early enteral nutrition (EEN) increases the blood flow of gut mucosa and stimulates the intestinal motility.
- Trial name
- NCT01507766
- Testing
- early enteral nutrition, Delayed enteral nutrition
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Nanjing University School of Medicine
Acute Compartment Syndrome
Predicting Acute Compartment Syndrome (PACS)
The long-term objective is to develop a tool to aid in making a timely and accurate diagnosis of acute compartment syndrome (ACS).
- Trial name
- PACS (NCT01561261)
- Testing
- Continuous tissue perfusion monitoring by near-infrared spectroscopy (NIRS) and intramuscular pressure (IMP)
- Where
- 7 sites in United States
- Volunteers
- 194 people
- Sponsor
- Major Extremity Trauma Research Consortium
Limb Ischemia, Compartment Syndrome of Leg
Chemical Analysis of Limb Microfluidics
Compartment syndrome (CS) is a condition where an increase in pressure in an anatomical compartment (e.g. the lower leg) affects the blood supply of the tissues, leading to tissue damage.
- Trial name
- CALM (NCT06050499)
- Testing
- Microdialysis catheter + biosensor
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- Imperial College London
Cholecystitis; Gallstone, Mechanical Ventilation Pressure High
The Effect of Ventilation Modes on Cerebral Oxymetry In Operation
In laparoscopic cholecystectomy method, Insufflation of CO2 in abdominal cavity causes positioning of the diaphragm upwards, a decrease in lung's volume and its compliance, an increase in the airway resistance, mismatch between…
- Conditions
- Cholecystitis; Gallstone, Mechanical Ventilation Pressure High, Intraabdominal Hypertension
- Trial name
- NCT04723043
- Testing
- mechanical ventilation modes
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Acute Pancreatitis, Intra-abdominal Hypertension
Neostigmine Treatment of Acute Pancreatitis Combined With Intra-abdominal Hypertension
Acute pancreatitis(A) often complicated with Intra-abdominal Hypertension. After the onset of acute pancreatitis, capillary leakage causing ascites,upper gastrointestinal tract obstruction and paralytic ileus leading to an…
- Trial name
- NCT02543658
- Testing
- Neostigmine Methylsulfate 1 MG/ML, Conservative treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Compartment Syndrome, Compartment Syndrome Nontraumatic Lower Extremity
From Blast Injury to Multicompartment Dysfunction:
Blast injuries can cause swelling and pressure problems in more than one part of the body. This study will review existing medical records of people treated for blast-related injuries to learn how often these problems affect…
- Conditions
- Compartment Syndrome, Compartment Syndrome Nontraumatic Lower Extremity, Compartment Syndrome Traumatic Upper Extremity, Compartment Syndromes
- Trial name
- BLAST-PCS (NCT07911085)
- Where
- Ukraine
- Volunteers
- 100 people
- Sponsor
- Ukrainian Society of Regional Anesthesia and Pain Therapy
Abdominal Compartment Syndrome
Relation Between Intrabdominal Pressure and Collapsibility Index of Inferior Vena Cava Before and After Fluid Therapy
This study assess the relation between intra abdominal pressure and collapsibility index of inferior vena cava in emergency bedside ultrasonography before and after fluid therapy.
- Trial name
- NCT01553422
- Testing
- Fluid therapy (Saline Normal)
- Where
- Iran
- Volunteers
- 82 people
- Sponsor
- Isfahan University of Medical Sciences
Intra Abdominal Pressure, Abdominal Compartment Syndrome
Intra-abdominal Hypertension and Abdominal Compartment Syndrome in Patients After Pancreatic Procedures.
This study investigates the development of intra-abdominal hypertension and compartment syndrome in patients undergoing elective pancreatic procedures.
- Conditions
- Intra Abdominal Pressure, Abdominal Compartment Syndrome, Pancreatic Surgery, Pancreatic Fistula After Pancreaticoduodenectomy
- Trial name
- HYPA (NCT06672601)
- Where
- Czechia
- Volunteers
- 150 people
- Sponsor
- Charles University, Czech Republic
Air or Gas Embolism, Carbon Monoxide Poisoning
Hyperbaric Oxygen Therapy Registry
The purpose of the Hyperbaric Oxygen Therapy Registry (HBOTR) is to provide real world patient outcome and side effect information from electronic health records submitted to a specialty specific hyperbaric registry as part of…
- Conditions
- Air or Gas Embolism, Carbon Monoxide Poisoning, Clostridial Myositis and Myonecrosis (Gas Gangrene), Crush Injury, Compartment Syndrome & Other Acute Traumatic Ischemias
- Trial name
- HBOTR (NCT02483650)
- Volunteers
- 5,000 people
- Sponsor
- U.S. Wound Registry
Compartment Syndrome of Forearm
Clinical Application and Validation of Innovative Tourniquet
Background: Tourniquets are the basic equipment for nurses to perform blood draws, and venous indwelling needles for congestion, or for hemostasis.
- Trial name
- NCT05605990
- Testing
- Innovative tourniquet (Acusense Nonpneumatic tourniquet)
- Where
- Taiwan
- Volunteers
- 160 people
- Sponsor
- National Cheng-Kung University Hospital
Acute Compartment Syndrome, Fracture, Bone
Evaluation of the Diagnostic and Therapeutic Value of Tissue Ultrafiltration in Patients at Risk of Acute Compartment Syndrome (ACS)
The goal of this clinical trial is to learn if tissue ultrafiltration (TUF) catheters can reduce intramuscular pressure and prevent acute compartment syndrome (ACS) in adults ages 18-60 with severe proximal tibia or tibial shaft…
- Conditions
- Acute Compartment Syndrome, Fracture, Bone, Tibial Fractures
- Trial name
- NCT05889559
- Testing
- Tissue Ultrafiltration Catheters
- Where
- 4 sites in United States
- Volunteers
- 60 people
- Sponsor
- Major Extremity Trauma Research Consortium
Compartment Syndrome
The Application of Near Infrared Spectroscopy (NIRS) in the Detection of Lower Limb Compartment Syndrome
This study aims to determine how infrared spectroscopy compares to continuous compartment pressure monitoring in the detection of compartment syndrome.
- Trial name
- NCT00921271
- Testing
- Monitoring of StO2
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Functional Dysphonia
Speech Therapy and Functional Dysphonia After Thyroidectomy
Following a thyroidectomy, voice and swallowing alterations, which more frequently would appear to be caused by lesions of the laryngeal nerve, may occur.
- Trial name
- LSCC (NCT05963178)
- Testing
- Pre-operative counselling
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
CEC Syndrome
Non-invasive Measurement of Compartment Pressure: Reliability
The investigators want to investigate the reliability (variability) of a new device, that should be able to measure lower leg compartment pressure non-invasively. Therefore the tool is used under different circumstances.
- Trial name
- NCT05720182
- Testing
- Compremium Compressibility Measurement, Treadmill Running, Questionnaire
- Where
- Netherlands
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Kay van Heeswijk