Clinical trials: Compartment Syndromes
Intra-Abdominal Hypertension, Inguinal Hernia
Measuring Intraabdominal Pressure, Lactic Acid, and Urine Output
This study serves as a pilot study with the intention to to measure intraabdominal pressure, lactic acid, and urine output in obese individuals undergoing laparoscopic inguinal hernia repair.
- Trial name
- NCT05070572
- Testing
- Accuryn Monitoring System
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Antonios Likourezos
Compartment Syndrome of Leg
Botox for the Treatment of Chronic Exertional Compartment Syndrome
After diagnosis of Chronic Exertional Compartment Syndrome (CECS), the participants will be referred to both physical therapy and Botox injection.
- Trial name
- NCT03922139
- Testing
- OnabotulinumtoxinA Injection
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Wisconsin, Madison
Intra-Abdominal Hypertension
Intra-Abdominal Hypertension in Neonatal Intensive Care Patients
The observational study is designed to determine the feasibility of performing Intra-Abdominal Pressure (IAP) via bladder pressure measurements and of tracking IAP in neonates who require bladder catheterization.
- Trial name
- NCT00747552
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Utah
Wounds and Injuries, Compartment Syndrome
Closure of Fasciotomy Wounds: A Prospective, Observational Study of a Continuous External Tissue Expander
Fasciotomy wounds are rarely able to be closed at the time of index surgery. They often require multiple returns to surgery for closure, and occasionally require skin grafting (i.e. they are never completely closed).
- Trial name
- NCT01171534
- Testing
- DermaClose fasciotomy closure, Vessel loop
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- University of Missouri-Columbia
Compartment Syndrome of Leg
Botox for the Treatment of Recurrent Chronic Exertional Compartment Syndrome
10 participants with Recurrent Chronic Exertional Compartment Syndrome (R-CECS) will be enrolled in a 6 month study at the University of Wisconsin Hospitals and Clinics to test the hypothesis that injection of Botox into the…
- Trial name
- NCT05006417
- Testing
- Botox
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of Wisconsin, Madison
HIV/AIDS
Body Compartment Pharmacokinetics of Anti-retroviral Agents That May be Considered for Future On-demand Peri-exposure HIV Prophylaxis Regimens
This study is being conducted to determine if the uptake of anti-HIV medication, called Genvoya®, at different time-frames, is different at several body sites, including mucosal tissues.
- Trial name
- NCT03976752
- Testing
- Genvoya
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Emory University
Hernia Repair With Compartment Syndrome
Feasibility Study of The Use of FLEX HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrix in The Closure of Abdominal Wall Defects With Component Separation in Clean or Contaminated Cases
This study examines the feasibility of using Flex HD® Surgical Implant or STRATTICE® Reconstructive Tissue Matrixin the repair of hernias.
- Trial name
- Flex HD (NCT01597128)
- Testing
- Flex HD, Strattice
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- John Roth
Intracranial Pressure Increase, Abdominal Compartment Syndrome
Vasopressin in Intraabdominal Pressure Elevation
The aim of this study is to investigate any direct correlation between increased intrathoracic pressure, intraabdominal pressure and intracranial pressure, following a controlled elevation in intraabdominal pressure and…
- Trial name
- NCT03707054
- Testing
- Study Arm
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Human Volunteers
In Vivo Optical Spectroscopy Monitoring in a New Model of Muscular Compartment Syndrome
Muscular compartment syndrome (MCS) is consecutive to an increase in intramuscular compartment pressures, and is a rare but serious postoperative complication.
- Trial name
- NCT01452425
- Testing
- Tourniquet, INVOS assessment, EMG assessment
- Where
- Belgium
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain
Anterior Knee Pain Syndrome
In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee
Anterior knee pain has been an enigmatic problem for orthopedic surgeons. Recent studies, as well as the clinical observation of the principle investigator have suggested that arthroscopic resection of the infrapatellar plica…
- Trial name
- NCT00643487
- Testing
- observation of the behavior of the infrapatellar plica
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
HIV Infections
Body Compartment PK for New HIV Pre-exposure Prophylaxis Modalities
The purpose of this study is to determine the ability of new anti-HIV agents to penetrate different body compartments in HIV negative men who have sex with men and transgender women.
- Trial name
- NCT02985996
- Testing
- Truvada, Genvoya
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Emory University
Chronic Exertional Compartment Syndrome
Botulinum for Chronic Exertional Compartment Syndrome
We will investigate the feasibility of a simple outpatient one time injection regimen for the treatment of Chronic Exertional Compartment Syndrome (CECS).
- Trial name
- Botox (NCT03339921)
- Testing
- Botulinum toxin injections for chronic compartment syndrome, surgical fasciotomy for chronic compartment syndrome
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- 375th Medical Group, Scott Air Force Base
Acute Pancreatitis, Intra-abdominal Hypertension
Neostigmine Treatment of Acute Pancreatitis Combined With Intra-abdominal Hypertension
Acute pancreatitis(A) often complicated with Intra-abdominal Hypertension. After the onset of acute pancreatitis, capillary leakage causing ascites,upper gastrointestinal tract obstruction and paralytic ileus leading to an…
- Trial name
- NCT02543658
- Testing
- Neostigmine Methylsulfate 1 MG/ML, Conservative treatment
- Where
- China
- Volunteers
- 80 people
- Sponsor
- The First Affiliated Hospital of Nanchang University
Chronic Exertional Compartment Syndrome
Comparison of Non-Surgical Treatment Options for Chronic Exertional Compartment Syndrome (CECS)
Chronic Exertional Compartment Syndrome (CECS) in the lower leg is a debilitating condition in highly active individuals. Pain occurs in 1 or several leg compartments upon an exertional activity, typically running, that quickly…
- Trial name
- NCT04409600
- Testing
- Supervised Gait Retraining, Home Based Gait Retraining, Saline Injection
- Where
- 4 sites in United States
- Volunteers
- 35 people
- Sponsor
- Walter Reed National Military Medical Center
HIV Infection
The Effect of Raltegravir on HIV Decay During Primary and Chronic Infection
The purpose of this study is to measure the decay characteristics of HIV in the blood of patients after taking a combination of anti-HIV drugs, which includes a new class of anti-HIV drug, an integrase inhibitor.
- Trial name
- PINT (NCT00641641)
- Testing
- Tenofovir + emtricitabine + raltegravir.
- Where
- 4 sites in Australia
- Volunteers
- 16 people
- Sponsor
- Kirby Institute