Clinical trials: Complex Aortic Aneurysms
Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations
Coagulation Factors Alterations in Patients Undergoing Complex Thoraco-abdominal Aortic Aneurysm Repair
This study will evaluate the impact of complex thoraco-abdominal aortic aneurysm repair in coagulation during the immediate postoperative period in patients undergoing omplex thoraco-abdominal aortic aneurysm repair.
- Conditions
- Thoraco-abdominal Aortic Aneurysm Repair, Coagulation Factors Alterations, Platelet Activation
- Trial name
- CoFA-TAAA (NCT06432387)
- Testing
- Patients undergoing complex thoraco-abdominal aortic aneurysm repair
- Where
- 2 sites in Greece
- Volunteers
- 58 people
- Sponsor
- University of Thessaly
Abdominal Aortic Aneurysm, Juxtarenal Abdominal Aortic Aneurysm
Evaluation of Clinical Efficacy and Safety of Aortal Stent-Graft Created Using 3D Printing Technology
the comparison of physician-modified stent-graft created in 3D models versus custom-made devices in the treatment of complex abdominal aortic aneurysm
- Conditions
- Abdominal Aortic Aneurysm, Juxtarenal Abdominal Aortic Aneurysm, Pararenal Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT06969729
- Testing
- Physician-Modified Fenestrated Stent-Graft (3D-Printed Template-Guided)
- Where
- Poland
- Volunteers
- 100 people
- Sponsor
- Samodzielny Publiczny Szpital Kliniczny nr 2 PUM
Juxta Renal Abdominal Aortic Aneurysm Without Rupture, Complex Aortic Aneurysms
Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic Aneurysms
The primary objective of the clinical investigation "Physician Modified Endovascular Grafts for the Treatment of Elective, Symptomatic or Ruptured Complex Aortic Aneurysms" is to assess the use of the Physician-Modified…
- Conditions
- Juxta Renal Abdominal Aortic Aneurysm Without Rupture, Complex Aortic Aneurysms, Aortic Aneurysm
- Trial name
- NCT06834607
- Testing
- Physician Modified Aortic Endograft repair for complex aortic aneurysm
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Akhilesh Jain
1 Paravisceral Abdominal Aortic Aneurysm, 2 Juxtarenal Abdominal Aortic Aneurysm
Chimney EndoVascular Aneurysm Sealing Of New Expanded Indication
Prospective, multi-center, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Complex Abdominal Aortic Aneurysms.
- Conditions
- 1 Paravisceral Abdominal Aortic Aneurysm, 2 Juxtarenal Abdominal Aortic Aneurysm, 3 Pararenal Abdominal Aortic Aneurysm, 4 Complex Abdominal Aortic Aneurysms
- Trial name
- ChEVAS One (NCT04252573)
- Testing
- Chimney Endovascular Aortic Sealing (ChEVAS) System
- Where
- 8 sites in United States
- Volunteers
- 13 people
- Sponsor
- Endologix
Complex Aortic Aneurysms
Analysis of Respiration-induced Deformities of the Visceral and Renal Arteries Before and After Stenting
Fenestrated stents are used for the management of complex juxta-renal, para-renal or thoracoabdominal aneurysms in patients with high surgical risk and/or contraindicated for open surgery.
- Trial name
- NCT04724863
- Testing
- Angioscan
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
AKI
Protection From Acute Kidney Injury (AKI) With Basis™ Treatment
This study is a single-center, prospective, randomized, double-blinded, placebo-controlled phase II clinical trial to evaluate the efficacy of "NAD+ supplementation" with Basis™ (Nicotinamide Riboside and Pterostilbene) in…
- Trial name
- NCT04342975
- Testing
- Nicotinamide Riboside + Pterostilbene
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Complex Aortic Aneurysms
MOSTEGRA TRIAL:MO-(Dified) STE-(nt) GRA(-ft): Surgeon-modified Fenestrated-branched Stent-grafts
This trial evaluates surgeon-modified fenestrated-branched stent-grafts (sm-FBSG) for Abdominal Aortic Aneurysms (AAA) that are custom-made intra-operatively with no waiting period by a qualified vascular surgeon.
- Trial name
- MOSTEGRA (NCT02101463)
- Testing
- surgeon-modified fenestrated-branched stent-grafts (sm-FBSG)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Northside Hospital, Inc.
Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm
Physician Modified Endograft For Complex Aortic Aneurysm Repair
The physician modified endograft is intended for treating complex, pararenal, juxtarenal and thoracoabdominal aortic aneurysms requiring coverage of renal arteries, the superior mesenteric artery or the celiac trunk in high-risk…
- Conditions
- Complex Abdominal Aortic Aneurysm, Juxtarenal Aortic Aneurysm, Pararenal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
- Trial name
- NCT05339061
- Testing
- Endovascular Treatment of Complex abdominal or Thorocoabdominal aneurysms (TAAA).
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of California, Davis
Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms
Complex Abdominal Aortic Aneurysm Repair With Fenestrated Stent Grafts
The purpose of this study is to evaluate clinical outcomes and quality of life measures in treated by endovascular aortic repair of juxtarenal, suprarenal, and type IV thoracoabdominal aortic aneurysms using custom-made Cook…
- Conditions
- Juxtarenal Aortic Aneurysms, Suprarenal Aortic Aneurysms, Type IV Thoracoabdominal Aortic Aneurysms
- Trial name
- NCT01937949
- Testing
- Custom-made Zenith® Fenestrated AAA Endovascular Graft:
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Gustavo S Oderich
Complex Aortic Aneurysms
Analysis of Respiration-induced Deformations in Visceral and Renal Arteries Before and After Stenting During Branched Stent Treatment.
Aneurysm of the abdominal aorta is defined by a loss of parallelism of the arterial wall. The main risk of this pathology is the rupture of the aneurysm which is life threatening and this risk increases with the size of the…
- Trial name
- BEVAR (NCT04991636)
- Testing
- Angioscan
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Centre Chirurgical Marie Lannelongue
Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting
Frailty and Physician Modified Fenestrated Endograft for Thoracoabdominal Aortic Pathologies
The primary objective of this single arm, prospective feasibility study, Impact of Frailty on Clinical Outcomes of Patients Treated for Thoracoabdominal and Complex Abdominal Aortic Aneurysms with Physician-Modified Fenestrated…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Thoracoabdominal; Aortic, Aneurysm, Dissecting, Pararenal Aneurysm, Frailty Syndrome
- Trial name
- NCT04524247
- Testing
- Physician Modified Endografts
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Southern California
Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm
CAAAs, TAAAs, Aortic Arch Aneurysms or Dissections With Fenestrated/Branched Stent Graft
The purpose of this study is to gather safety and effectiveness of the Zenith t-Branch and customized physician-specified stent-graft with a combination of fenestrations and/or branches to repair aortic aneurysm.
- Conditions
- Complex Abdominal Aortic Aneurysm, Thoracoabdominal Aortic Aneurysm, Aortic Arch Aneurysm, Aortic Arch Dissection
- Trial name
- NCT02089607
- Testing
- CAAA and TAAA Arm, Aortic Arch Aneurysm Arm
- Where
- 3 sites in United States
- Volunteers
- 760 people
- Sponsor
- Gustavo S Oderich
Aortic Aneurysms
Medical & Economical Evaluation of Fenestrated & Branched Stent-grafts to Treat Complex Aortic Aneurysms
The aim of this study is to prospectively compare the perioperative mortality severe morbidity and the costs of endovascular versus conventional surgical repair of pararenal, supra-renal and type 4 THORACO-abdominal aortic…
- Trial name
- Windows1 (NCT01168037)
- Testing
- Endovascular aortic repair with branched/fenestrated stent-graft, Open Surgical Repair
- Where
- France
- Volunteers
- 270 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Thoracoabdominal Aortic Aneurysm, Endovascular Repair
Clinical Trial of BAO-G Technique in Complex Aortic Aneurysm Endovascular Repair (BAO-G-02)
Multi-Branch AOrtic Reconstruction With G-iliac System (BAO-G) Technique is a novel technique of endovascular repair of complex aortic aneurysm, which using off-the-shelf iliac branched devices to reconstruct the visceral…
- Conditions
- Thoracoabdominal Aortic Aneurysm, Endovascular Repair, Complex Aortic Aneurysms
- Trial name
- BAO-G-02 (NCT07141251)
- Testing
- BAO-G
- Where
- 11 sites in China
- Volunteers
- 60 people
- Sponsor
- Peking Union Medical College Hospital
Thoracic Aortic Aneurysm
Intravascular Ultrasound (IVUS) in Complex Aortic Endovascular Interventions
The study aims to investigate the applicability of intravascular ultrasound (IVUS) in the endovascular therapy of juxta-, supra- and thoracoabdominal aortic aneurysms.
- Trial name
- NCT04663074
- Testing
- IVUS control
- Where
- 6 sites in Denmark, Germany and 2 more
- Volunteers
- 80 people
- Sponsor
- University Hospital Muenster
Aortic Aneurysm, Abdominal, Thoracic Aneurysm
Clinical Outcomes and Radiation Safety After Endovascular Repair of Complex AAAs Using Fenestrated- Branched Devices
The purpose of this study is to assess the clinical outcomes and radiation of the use of off-the-shelf and custom-made devices (CMDs) for the endovascular repair of juxtarenal, suprarenal, thoracoabdominal and arch aortic…
- Trial name
- NCT02266719
- Testing
- Fenestrated CMD, Type I - III TAAA, Arch cohort
- Where
- 4 sites in United States
- Volunteers
- 750 people
- Sponsor
- Carlos Timaran
Thoracoabdominal Aortic Aneurysm
Automated Carbon Dioxide Angiography in Fenestrated/Branched Endovascular Abdominal Aortic Aneurysm Repair
Carbon Dioxide (CO2)-based angiography is a digital subtraction angiography (DSA), where CO2 is used as an intra-arterial contrast agent.
- Trial name
- NCT06103942
- Testing
- CO2 angiography
- Volunteers
- 30 people
- Sponsor
- Uppsala University
Thoracoabdominal Aortic Aneurysm, Without Mention of Rupture
BGP+ Stent as Bridging Stent in BEVAR
The objective of this clinical investigation is to evaluate, in a controlled setting, the safety and performance of the BGP+ balloon expandable covered stent Graft System (Bentley InnoMed, Hechingen, Germany) implanted as…
- Trial name
- NCT03982940
- Testing
- BGP+ Stent Graft System as bridging stent
- Where
- 10 sites in Germany
- Volunteers
- 118 people
- Sponsor
- Marc Bosiers, MD
Aneurysm Aortic, Vascular Diseases
F-BEVAR vs Open Surgery for Complex Abdominal Aortic Aneurysm
The aim of the present study was to investigate outcomes of a propensity matched series of patients treated with F-BEVAR and open surgery repair for complex abdominal aortic aneurysm in two aortic high-volume centres.
- Trial name
- NCT05247944
- Testing
- Fenestrated and branched endovascular aortic repair (F-BEVAR), Open repair
- Volunteers
- 278 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Abdominal Aortic Aneurysms, Thoracoabdominal Aneurysms
Physician-Modified Endografts for Complex Aortic Aneurysms and Thoracoabdominal Aneurysm Repair in High-Risk Patients
This single-arm FDA-monitored protocol intends to broaden endovascular device applicability using physician-modifications in patients who A) Have anatomical conditions not amenable to endovascular repair using currently marketed…
- Conditions
- Abdominal Aortic Aneurysms, Thoracoabdominal Aneurysms, Pararenal Aortic Aneurysm
- Trial name
- PMEG (NCT07224230)
- Testing
- Physician Modified Endograft
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Steven Maximus