Clinical trials: Complex Post-Traumatic Stress Disorder
Safety, Psychological, Acceptability of Health Care
Body-oriented Psychotherapy for Individuals With a History of Child Maltreatment and Trauma-related Symptoms
This Pilot Randomized Controlled Trial (RCT) overall aim is to establish the safety, feasibility, acceptability and preliminary effects of a body-oriented psychotherapy, Somatic Experiencing (SE), on social functioning and mental…
- Conditions
- Safety, Psychological, Acceptability of Health Care, Psychological Safety, Maltreatment, Child
- Trial name
- NCT06549777
- Testing
- SE-group, Control
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Monique Pfaltz
Complex Post-Traumatic Stress Disorder (CPTSD)
RECONNECT - Treatments for Complex PTSD
Complex PTSD (CPTSD) is a new diagnosis for which no established gold-standard treatment(s) yet exists. In this trial, three psychotherapies, Prolonged Exposure (PE), Eye Movement Desensitization and Reprocessing (EMDR), and…
- Trial name
- NCT07863089
- Testing
- Prolonged Exposure, EMDR, ESTAIR
- Volunteers
- 225 people
- Sponsor
- University of Copenhagen
Posttraumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
Using Data Science To Center Patient Perspectives in Mechanism Discovery
Including patient perspectives when developing new therapy interventions is crucial because it can help to understand response heterogeneity and promote engagement.
- Trial name
- CPP (NCT06233968)
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Cambridge Health Alliance
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Complex Post-Traumatic Stress Disorder
NEST: A Group Intervention for Parents With Complex PTSD
The goal of this pilot clinical trial is to learn whether NEST, a new trauma-informed group therapy program, is feasible and acceptable for parents with Complex PTSD, a condition that can develop after prolonged or repeated…
- Trial name
- NCT07766265
- Testing
- Trauma-Informed Parenting Group Intervention
- Where
- 3 sites in Switzerland
- Volunteers
- 32 people
- Sponsor
- St.Gallen University of Applied Sciences
Complex Post-Traumatic Stress Disorder
Treatment of Complex Post-traumatic Stress Disorder Among Displaced People in Switzerland and Germany
In WHO ICD-11 (its latest edition), the diagnostic criteria for post-traumatic stress disorder (PTSD) were revised, and a new sibling disorder, complex post-traumatic stress disorder (CPTSD) was introduced.
- Trial name
- ESTAIR_REFUGEE (NCT07015567)
- Testing
- Emotion regulation module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET), Negative self-concept module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET), Interpersonal relationships module of Enhanced Skills Training in Affective and Interpersonal Regulation combined with Narrative Exposure Therapy (ESTAIR/NET)
- Where
- 8 sites in Germany, Switzerland
- Volunteers
- 288 people
- Sponsor
- Eva Heim
Post-traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD)
Two-Year Follow-up Study on Children Exposed to Trauma
In our clinic, we plan to conduct research two years after the initial assessments (January-April 2024 and one year ago, January-June 2025) of children and adolescents with trauma exposure who were evaluated as part of their…
- Trial name
- Complex PTSD (NCT07697534)
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Istanbul University
Post Traumatic Stress Disorder, Complex Post-Traumatic Stress Disorder
A Pilot Study of Trauma-Focused Cognitive-Behavioral Therapy for Treatment of Post-traumatic Stress in Adults.
Post-traumatic stress disorder (PTSD) is a mental health condition that's triggered by the experience of potentially traumatic events.
- Trial name
- NCT06516874
- Testing
- Trauma-Focused Cognitive Behavioral Therapy for complex presentation (TF-CBT-CP)
- Where
- 5 sites in Chile
- Volunteers
- 13 people
- Sponsor
- University of Talca
Complex Insomnia
Effectiveness of Combining Behavioral and Pharmacologic Therapy for Complex Insomnia in Veterans With PTSD
Obstructive sleep apnea (OSA) is commonly reported in Veterans with post-traumatic stress disorder, which can potentiate symptoms of anxiety and depression, daytime symptoms and worsen nightmares.
- Trial name
- PRECEPT-D (NCT03937713)
- Testing
- eszopiclone, Brief behavioral therapy for insomnia
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- VA Office of Research and Development
Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD)
Implementing a Therapy for Complex Trauma in French-Speaking Settings
Many individuals living with borderline personality disorder (BPD) have experienced childhood trauma, such as abuse or neglect. A significant number of them also meet the criteria for post-traumatic stress disorder (PTSD).
- Conditions
- Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- TRAUL (NCT07123974)
- Testing
- Dialectical Behaviour Therapy for Post-Traumatic Stress Disorder (DBT-PTSD)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder
Building Resilience at Schools: Emotional and Biological Assessment and Treatment of Traumatic Stress
In the last four years alone, residents of Puerto Rico have experienced a slew of natural disasters including Hurricane Maria in 2017, earthquakes in 2019 and 2020, the continued COVID-19 pandemic from 2020-2022, and most…
- Conditions
- Post Traumatic Stress Disorder, Complex Posttraumatic Stress Disorder, Stress, Burn Out
- Trial name
- NCT05701111
- Testing
- Start with the Heart Students, Start with the Heart Teachers, Cue Centered Therapy Counselors
- Where
- 3 sites in United States, Puerto Rico
- Volunteers
- 80,800 people, healthy volunteers welcome
- Sponsor
- Stanford University
PTSD, Complex Post-Traumatic Stress Disorder
8-day Intensive Treatment Programme for PTSD and CPTSD in Sweden
Post-Traumatic Stress Disorder (PTSD) and Complex PTSD (C-PTSD) are conditions that may develop after a person has been exposed to extremely stressful experiences.
- Trial name
- 8-day ITP (NCT06645028)
- Testing
- Intensive treatment programme, Treatment as Usual (TAU)
- Where
- Sweden
- Volunteers
- 118 people
- Sponsor
- Christina Blomdahl
Post-Traumatic Stress Disorder Complex, Emotional Dysregulation
Child-Parent Psychotherapy After the 2023 Kahramanmaraş Earthquake
This study aims to evaluate the effectiveness of Child-Parent Psychotherapy (CPP) in reducing trauma-related symptoms and improving attachment quality among preschool-aged children who experienced the 2023 Kahramanmaraş…
- Trial name
- NCT07040462
- Testing
- Child-Parent Psychotherapy (CPP)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Beykoz University
Chronic Insomnia, Sleep Deprivation
Evaluating the Efficacy and Safety of PROSOMNIA Sleep Therapy™ in Patients With Sleep Deprivation and Chronic Insomnia
This clinical trial aims to evaluate the safety and efficacy of PROSOMNIA Sleep Therapy (PSTx) for individuals suffering from chronic insomnia, sleep deprivation, and REM sleep disorders.
- Conditions
- Chronic Insomnia, Sleep Deprivation, REM Behavior Disorder, REM Sleep Behavior Disorder
- Trial name
- PSHW (NCT06644573)
- Testing
- PROSOMNIA Sleep Therapy™ (PSTx), Anesthesia-Induced Sleep Therapy, Diprivan (propofol), Astra-Zeneca
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Nyree Penn
Post-traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD)
Follow-Up Study on Children Exposed to Trauma
As far as it is known, there is no longitudinal study in Turkey investigating the follow-up and treatment of children and adolescents exposed to trauma.
- Trial name
- NCT06975852
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Istanbul University
Complex Post-Traumatic Stress Disorder (CPTSD), Post-traumatic Stress Disorder (PTSD)
Prevalence of Complex PTSD in Trauma-Exposed Children-Adolescents and Related Factors
The aim of this study is to assess the psychiatric evaluation of children and adolescents exposed to trauma in the outpatient clinic and to determine the prevalence of PTSD and Complex PTSD (CPTSD) diagnoses.
- Trial name
- NCT06918899
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
Complex Post-Traumatic Stress Disorder
Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study
Modular Patient Centred CBT (MPC) for Complex PTSD (CPTSD) is a manualized psychotherapy programme that consists of five treatment modules addressing 1) Affect dysregulation, 2) Disturbed relationships, 3) Negative self-concept…
- Trial name
- PACE pilot RCT (NCT05259592)
- Testing
- Psychotherapy
- Where
- 5 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Veterans Centre
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Study of Emotional Dysregulation in Complex Post-Traumatic Stress Disorder
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-traumatic Stress Disorder (PTSD)
- Trial name
- TR-EMA (NCT06848127)
- Testing
- Self-questionnaires, Cognitive assessment, Momentary Ecological Assessment (EMA)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Complex Post-Traumatic Stress Disorder
Complex-Posttraumatic Stress Disorder - Cultural Adaptation of a Therapeutic Manual and Development of a Culture-specific Diagnostic Module for Refugee Populations in Switzerland (Pilot Trial)
In January 2022, the World Health Organization (WHO) launched the 11th edition of the International Classification of Diseases (ICD-11).
- Trial name
- NCT05917613
- Testing
- Enhanced Skills Training in Affective and Interpersonal Regulation combined with Modified Prolonged Exposure (ESTAIR/MPE)
- Where
- 2 sites in Switzerland
- Volunteers
- 24 people
- Sponsor
- Eva Heim
Post Traumatic Stress Disorder PTSD, Quality of Life
Effectiveness of Trauma Treatment in the Specialist Health Care Services
Post-traumatic stress disorder (PTSD) is a common mental illness. Treatments for PTSD are regarded as highly effective, but a large-scale, prospective, longitudinal randomized controlled trial comparing the effectiveness of these…
- Conditions
- Post Traumatic Stress Disorder PTSD, Quality of Life, Functional Outcome, Complex Post-Traumatic Stress Disorder
- Trial name
- NCT06691347
- Testing
- Eye movement desensitization and reprocessing, Cognitive therapy for PTSD
- Where
- Norway
- Volunteers
- 270 people
- Sponsor
- Vestre Viken Hospital Trust