Clinical trials: Complex Posttraumatic Stress Disorder (cPTSD)
Complex Post-Traumatic Stress Disorder (CPTSD)
RECONNECT - Treatments for Complex PTSD
Complex PTSD (CPTSD) is a new diagnosis for which no established gold-standard treatment(s) yet exists. In this trial, three psychotherapies, Prolonged Exposure (PE), Eye Movement Desensitization and Reprocessing (EMDR), and…
- Trial name
- NCT07863089
- Testing
- Prolonged Exposure, EMDR, ESTAIR
- Volunteers
- 225 people
- Sponsor
- University of Copenhagen
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Study of Emotional Dysregulation in Complex Post-Traumatic Stress Disorder
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-traumatic Stress Disorder (PTSD)
- Trial name
- TR-EMA (NCT06848127)
- Testing
- Self-questionnaires, Cognitive assessment, Momentary Ecological Assessment (EMA)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- University Hospital, Strasbourg, France
Complex Post-Traumatic Stress Disorder
NEST: A Group Intervention for Parents With Complex PTSD
The goal of this pilot clinical trial is to learn whether NEST, a new trauma-informed group therapy program, is feasible and acceptable for parents with Complex PTSD, a condition that can develop after prolonged or repeated…
- Trial name
- NCT07766265
- Testing
- Trauma-Informed Parenting Group Intervention
- Where
- 3 sites in Switzerland
- Volunteers
- 32 people
- Sponsor
- St.Gallen University of Applied Sciences
Post Traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD)
Psychometric Properties of the International Trauma Interview (ITI) for ICD-11 PTSD and CPTSD
The aim of the project is to evaluate the psychometric properties (e.g. validity, reliability) of the International Trauma Interview (ITI) - German version.
- Trial name
- NCT04086654
- Testing
- International Trauma Interview (ITI) for ICD-11 PTSD and Complex PTSD - German version
- Where
- Switzerland
- Volunteers
- 77 people
- Sponsor
- University of Zurich
Complex Posttraumatic Stress Disorder
PACE Versus PE for CPTSD (PACE Trial)
The objective of this pragmatic trial is to evaluate the beneficial and harmful effects of Patient-centred Modular Cognitive Behavioural Therapy (PACE) compared with the standard post-traumatic stress disorder (PTSD) treatment…
- Trial name
- PACE (NCT07371156)
- Testing
- PACE, PE
- Where
- 10 sites in Denmark
- Volunteers
- 228 people
- Sponsor
- Sofie Folke
Complex Post-Traumatic Stress Disorder (CPTSD), Post-traumatic Stress Disorder (PTSD)
Prevalence of Complex PTSD in Trauma-Exposed Children-Adolescents and Related Factors
The aim of this study is to assess the psychiatric evaluation of children and adolescents exposed to trauma in the outpatient clinic and to determine the prevalence of PTSD and Complex PTSD (CPTSD) diagnoses.
- Trial name
- NCT06918899
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Istanbul University
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Group Guided Written Exposure Therapy for CPTSD Symptoms Among Adolescents
This study aims to examine the effectiveness of group-delivered Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT06931093
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive counselling
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University
Post-traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD)
Follow-Up Study on Children Exposed to Trauma
As far as it is known, there is no longitudinal study in Turkey investigating the follow-up and treatment of children and adolescents exposed to trauma.
- Trial name
- NCT06975852
- Where
- Turkey (Türkiye)
- Volunteers
- 210 people
- Sponsor
- Istanbul University
Complex Post-Traumatic Stress Disorder
Patient-centered Modular CBT for CPTSD: A Randomised Controlled Pilot Study
Modular Patient Centred CBT (MPC) for Complex PTSD (CPTSD) is a manualized psychotherapy programme that consists of five treatment modules addressing 1) Affect dysregulation, 2) Disturbed relationships, 3) Negative self-concept…
- Trial name
- PACE pilot RCT (NCT05259592)
- Testing
- Psychotherapy
- Where
- 5 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Danish Veterans Centre
Complex Posttraumatic Stress Disorder (cPTSD), Dissociative Disorder Not Otherwise Specified (DDNOS)
Emotional and Cognitive Self-regulation, an EEG Study
The main goal of the proposed project is to assess treatment-induced changes of electrophysiological and psychophysiological correlates of the capacity to regulate emotion, executive functions, and clinical measures in…
- Conditions
- Complex Posttraumatic Stress Disorder (cPTSD), Dissociative Disorder Not Otherwise Specified (DDNOS), Dissociative Identity Disorder (DID)
- Trial name
- ECSR (NCT02459340)
- Testing
- therapeutic treatment (inpatient and outpatient setting)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yolanda Schlumpf, PhD
PTSD, Complex Post-Traumatic Stress Disorder
8-day Intensive Treatment Programme for PTSD and CPTSD in Sweden
Post-Traumatic Stress Disorder (PTSD) and Complex PTSD (C-PTSD) are conditions that may develop after a person has been exposed to extremely stressful experiences.
- Trial name
- 8-day ITP (NCT06645028)
- Testing
- Intensive treatment programme, Treatment as Usual (TAU)
- Where
- Sweden
- Volunteers
- 118 people
- Sponsor
- Christina Blomdahl
Complex Post-Traumatic Stress Disorder
RESTORE Trial: A Pilot RCT of Enhanced Skills Training in Affective and Interpersonal Regulation (ESTAIR) for Veterans With CPTSD
Complex Post traumatic Stress Disorder (CPTSD) is now recognized as a separate trauma-based psychological condition to PTSD. CPTSD is a broader diagnosis that includes the core PTSD symptoms (re-experiencing in the here and now…
- Trial name
- NCT04752072
- Testing
- Enhanced Skills Training in Affective and Interpersonal Regulation, Treatment as usual
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Combat Stress
Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD)
Implementing a Therapy for Complex Trauma in French-Speaking Settings
Many individuals living with borderline personality disorder (BPD) have experienced childhood trauma, such as abuse or neglect. A significant number of them also meet the criteria for post-traumatic stress disorder (PTSD).
- Conditions
- Borderline Personality Disorder (BPD), Complex Post-Traumatic Stress Disorder (CPTSD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- TRAUL (NCT07123974)
- Testing
- Dialectical Behaviour Therapy for Post-Traumatic Stress Disorder (DBT-PTSD)
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD)
Symptom Assessment in Adolescents Placed on Child Welfare
This study aims to characterize emotional dysregulation in complex post-traumatic stress disorder (cPTSD) and to determine the extent to which it can promote the distinction with borderline personality disorder (BPD) and…
- Conditions
- Complex Post-Traumatic Stress Disorder (CPTSD), Borderline Personality Disorder (BPD), Post-Traumatic Stress Disorder, PTSD
- Trial name
- PePsAdoTND (NCT07794332)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
CPTSD, Compelx Post-traumatic Stress Disorder
The Effectiveness of Guided Written Exposure Therapy for Complex PTSD in Adolescents
This study aims to examine the effectiveness of group Guided Written Exposure Therapy for Complex Post-Traumatic Stress Disorder (GWE-C) among Chinese adolescents through a randomized controlled trial.
- Trial name
- NCT07325734
- Testing
- Group Guided Written Exposure Therapy for CPTSD (GWE-C), Supportive Group
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- Peking University
Post-traumatic Stress Disorder (PTSD), Complex Post-Traumatic Stress Disorder (CPTSD)
Two-Year Follow-up Study on Children Exposed to Trauma
In our clinic, we plan to conduct research two years after the initial assessments (January-April 2024 and one year ago, January-June 2025) of children and adolescents with trauma exposure who were evaluated as part of their…
- Trial name
- Complex PTSD (NCT07697534)
- Where
- Turkey (Türkiye)
- Volunteers
- 136 people
- Sponsor
- Istanbul University
Non Suicidal Self Injury
The Effect of Intravenous Ketamine on Non Suicidal Self Injuries.
Non-suicidal self-injuries (NSSI) is a deliberate harm a person causes directly to their body, resulting in structural or functional damage, without suicidal ideation.
- Trial name
- NCT04242914
- Testing
- Ketamine, Midazolam
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Neuropsychological Rehabilitation Program (VIRTRAEL/LUCCIDY), Standard Training (TAU)
The Role of Executive Functioning in Complex Post-Traumatic Stress Disorder Among Female Survivors of Intimate Partner Violence
This project aims to investigate neuropsychological alterations in women with PTSD (Post-Traumatic Stress Disorder) and complex PTSD (CPTSD), survivors of intimate partner violence (IPV), and to implement a cognitive stimulation…
- Trial name
- BELIEVE-CPTSD (NCT06706882)
- Testing
- Experimental Training: VIRTRAEL/LUCCIDY, Active Comparator: Standard Training: Reflection Group (TAU) (Andalusian Institute of Women, 2010)
- Where
- Spain
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada