Clinical trials: Complex Symptom Disorders
Pilonidal Disease, Recurrence
Unroofing Curettage for Pilonidal Disease
This study aimed to investigate the outcomes of patients who underwent UC as the primary intervention for simple or complex SPD
- Conditions
- Pilonidal Disease, Recurrence, Healing Wound
- Trial name
- NCT05339828
- Testing
- unroofing curettage
- Where
- Turkey (Türkiye)
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- Ankara Diskapi Training and Research Hospital
Crohns Disease, Fistula
A Study of Surgical Interventions in Fistulizing Conditions
In this study, participants with complex fistulizing conditions will be treated with surgical interventions according to their clinic's standard practice.
- Conditions
- Crohns Disease, Fistula, Rectovaginal Fistula, Complex Perianal Fistula
- Trial name
- NCT04940611
- Where
- 41 sites in United States, Austria and 8 more
- Volunteers
- 646 people
- Sponsor
- Takeda
Bandage, Pain
Impacts of a Standardized Musical Intervention on Complex Dressing Care During Home Hospitalization (MUCAFOCSS)
In France, home hospitalization services (HAD) are developing as an alternative to conventional hospitalization. In order to intervene at patients' home, a reason for referral must be defined.
- Conditions
- Bandage, Pain, Anxiety
- Trial name
- MUCAFOCSS (NCT04038593)
- Testing
- Youtube© relaxation music, MUSIC CARE© intervention
- Where
- France
- Sponsor
- Fondation Oeuvre de la Croix Saint-Simon
Atrial Fibrillation, Catheter Ablation
Benefit of Complex Fractionated Atrial Electrograms Elimination in Atrial Fibrillation Ablation
The aim of this study is to evaluate whether performing complex fractionated atrial electrograms ablation improves outcomes in persistent or atrial fibrillation ablation.
- Trial name
- NCT00873067
- Testing
- Additional Complex Fractionated Electrograms ablation, Standard atrial fibrillation ablation procedure
- Where
- Spain
- Volunteers
- 142 people
- Sponsor
- Hospital Clinic of Barcelona
Premature Ventricular Contractions, Congestive Heart Failure
Early Elimination of Premature Ventricular Contractions in Heart Failure
Premature ventricular contractions (PVC) are a very common irregular heart beat (arrhythmias) even in patients without heart disease. Frequent PVCs are thought to occur in about 1-4% of the general population.
- Trial name
- EVAC-HF (NCT01757067)
- Testing
- PVC ablation
- Where
- 8 sites in United States, Canada
- Volunteers
- 3 people
- Sponsor
- University of Maryland, Baltimore
Premature Ventricular Contraction
LLTS to Treat Premature Ventricular Contractions
This randomized control trial is designed to explore the effect of low-level tragus stimulation in patients with frequent premature ventricular contractions.
- Trial name
- TREAT-PVC (NCT04909528)
- Testing
- Low-level tragus stimulation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Bleeding, Cardiac Defect
ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery
In pediatric patients (newborns and infants weighing less than 10 kg) undergoing cardiac surgery with extracorporeal circulation postoperative bleeding represents a known complication with a significant impact on outcome.
- Conditions
- Bleeding, Cardiac Defect, Surgery--Complications, Fibrinogenopenia; Acquired
- Trial name
- ZEPLAST-PED (NCT04434001)
- Testing
- Fibrinogen Concentrate Human, Prothrombin Complex Concentrate, Fresh Frozen Plasma
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Policlinico S. Donato
Renal Stone
Standard PCNL Vs Endoscopic Combined Intrarenal Surgery (ECIRS) for Complex Nephrolithiasis in Obese Patients
Primary aim: comparing the efficacy of standard PCNL and endoscopic combined intrarenal surgery (ECIRS) in the Galdakao-modified Supine Valdivia (GMSV) position in a single session for the treatment of complex nephrolithiasis in…
- Trial name
- ECIRS (NCT06085794)
- Testing
- Endoscopic combined intrarenal surgery, Percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Mitral Valve Prolapse, Cardiac Arrhythmia
Mitral Valve Prolapse, Arrhythmias and Mitral Valve Surgery
Mitral valve prolapse (MVP) is associated with malignant ventricular arrhythmias (VA) and sudden cardiac death. A proper electrophysiological and echocardiographic characterization of this population is missing.
- Trial name
- MVP-A&S (NCT05562804)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Ospedale San Raffaele
Growth Failure in Medically Complex Infants, Growth Failure
Medical Nutrition Therapy for Medically Complex Infants in the Pediatric Outpatient Setting
The purpose of this study is to compare standardized nutrition therapy provided by a registered dietitian (RD) at regularly scheduled intervals to usual care in terms of the ability to improve growth parameters in medically…
- Conditions
- Growth Failure in Medically Complex Infants, Growth Failure, Malnutrition in Medically Complex Infants, Malnutrition
- Trial name
- NCT03522558
- Testing
- Standardized Medical Nutrition Therapy, Usual Care
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Alopecia
Safety and Tolerability of Hair Stimulating Complex (HSC) in Female Pattern Hair Loss
This double-blind placebo-controlled study will assess the tolerability, feasibility, and pharmacodynamics of intradermal Hair Stimulating Complex (HSC) in up to 18 of 27 women with Ludwig 1 or 2 classification or the Savin…
- Trial name
- NCT03662854
- Testing
- Hair Stimulating Complex (HSC), Phosphate Buffered Saline
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Histogen
Tuberous Sclerosis Complex, Self-injury
Rapalogues for Autism Phenotype in TSC: A Feasibility Study
The purpose of this study is to assess the feasibility and safety of administering rapalogues, sirolimus or everolimus, in participants with Tuberous Sclerosis Complex (TSC) and self-injury and to measure cognitive and behavioral…
- Conditions
- Tuberous Sclerosis Complex, Self-injury, Autism
- Trial name
- RAPT (NCT01929642)
- Testing
- Sirolimus, Everolimus
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Thymoma
Efficacy of Octreotide Treatment in Patients With Primary Inoperable Thymoma
This study will investigate the efficacy of treatment with octroetide in patients with primary inoperable thymoma to reduce tumor size.
- Trial name
- NCT00332969
- Testing
- Octreotide
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- Novartis Pharmaceuticals
Video Game Addiction, Gaming Disorder
Community-Based Intervention to Reduce Problematic Video Game Use in First-Year Secondary School Students: A Cluster Randomised Controlled Trial
This cluster randomised controlled trial will evaluate whether a community-based, multicomponent intervention can reduce problematic video game use and gaming disorder among first-year secondary school students in Pontevedra…
- Trial name
- AQJ (NCT07357792)
- Testing
- Community-Based Component, Adolescent Mindfulness Component, Adult Mindfulness Component
- Where
- Spain
- Volunteers
- 492 people, healthy volunteers welcome
- Sponsor
- Fundacin Biomedica Galicia Sur
Chronic Pain, Low Back Pain
Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain
The purpose of this study is to investigate, in two phases: (1) the feasibility and safety of Virtual Embodiment Therapy in treating chronic pain of lower back and upper limbs and (2) the efficacy of Virtual Embodiment Therapy on…
- Conditions
- Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction
- Trial name
- NCT04060875
- Testing
- Karuna Labs Virtual Reality Software
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Karuna Labs Inc.
Intracranial Hemorrhage, Traumatic, Intracranial Hemorrhage, Spontaneous
FFP Versus PCC in Intracranial Hemorrhage
The goal of this study will be to determine whether PCC confers any benefits over FFP in traumatic and spontaneous intracranial hemorrhage with respect to multiple factors including time to correction, absolute international…
- Trial name
- NCT02429453
- Testing
- Four Factor Prothrombin Complex Concentrate, Fresh Frozen Plasma
- Where
- United States
- Sponsor
- University of Utah
Postherpetic Neuralgia, Diabetic Neuropathy
A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions
Patients with postherpetic neuralgia (PHN), diabetic neuropathy (DN), complex regional pain syndrome (CRPS), carpal tunnel syndrome, HIV neuropathy, idiopathic sensory neuropathy, or other peripheral neuropathy participated in a…
- Conditions
- Postherpetic Neuralgia, Diabetic Neuropathy, Complex Regional Pain Syndrome, Carpal Tunnel Syndrome
- Trial name
- NCT00904202
- Testing
- Gabapentin + Lidoderm®
- Where
- 7 sites in United States
- Volunteers
- 62 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Neurologic Disorder, Chronic Disease
Parent-Reported Symptom Assessments in Children Taking Multiple Medications
This study plans to learn about how to measure symptoms (like tiredness or rash) in children with special healthcare needs who take 5 or more medications. Sometimes symptoms change in severity over time or new symptoms develop.
- Conditions
- Neurologic Disorder, Chronic Disease, Pediatric Disorder
- Trial name
- PRSA (NCT03849066)
- Testing
- Parent-Reported Symptom Assessment
- Where
- United States
- Volunteers
- 136 people
- Sponsor
- University of Colorado, Denver
Premature Ventricular Complexes Multiple, Premature Ventricular Contraction
The Prognostic Significance of Premature Ventricular Complexes in Patients Without Structural Heart Disease
With this project the investigators aim to investigate whether premature ventricular complexes (PVC) have a prognostic significance in persons without structural heart disease.
- Trial name
- PULSE (NCT03370679)
- Where
- Sweden
- Volunteers
- 1,000 people
- Sponsor
- Danderyd Hospital
Drug Resistant Epilepsy, Drop Seizures
Novel Helmet Design in Patients With Seizures
This is a two-part study that aims to determine the reliability and safety of the use of the Hövding inflatable helmet in seizures, as evidenced by the deployment of the helmet during seizures, and qualitative patient reporting.
- Conditions
- Drug Resistant Epilepsy, Drop Seizures, Generalized Tonic Clonic Seizure, Complex Partial Seizure
- Trial name
- NCT03443388
- Testing
- Hövding inflatable helmet
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Michael A. Gelfand, MD, PhD