Clinical trials: Complex Symptom Disorders
Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation
A Study Assessing Arrhythmia Mapping With a Multi-Electrode Mapping Catheter
The purpose of this study is to assess the safety and feasibility of the investigational catheter for mapping the atrial and ventricular regions of the heart.
- Conditions
- Scar-related Atrial Tachycardia, Persistent Atrial Fibrillation, Paroxysmal Atrial Fibrillation, Ventricular Tachycardia
- Trial name
- FEATHER (NCT07116525)
- Testing
- Paddle-Shaped, High-Density, Multi-Electrode Mapping Catheter
- Where
- 5 sites in Belgium, France and 1 more
- Volunteers
- 90 people
- Sponsor
- Biosense Webster, Inc.
Anal Fistula
Ligation of Intersphincteric Fistula Tract Versus Rectal Advancement Flap in the Treatment of Complex Anal Fistula
Objective: Rectal advancement flap (RAF) is currently considered the gold standard in the treatment of complex anal fistula (CAF). Clinical trials are a priority given the few consistent results available with level 1 evidence.
- Trial name
- LIFTRAF-RCT (NCT05263661)
- Testing
- LIFT, FLAP
- Volunteers
- 72 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Mycobacterium Avium-intracellulare Infection, HIV Infections
Rifabutin Therapy for the Prevention of Mycobacterium Avium Complex (MAC) Bacteremia in HIV Positive Patients With CD4 Counts = or < 200: Treatment IND Study
Primary: To provide rifabutin to HIV positive patients in an attempt to prevent or delay Mycobacterium avium Complex (MAC) infection by a daily dose of rifabutin.
- Trial name
- NCT00002080
- Testing
- Rifabutin
- Where
- United States
- Sponsor
- Pharmacia
Atrial Fibrillation, Persistent
Waveform Periodicity Analysis of Complex Fractionated Electrograms in Patients With Persistent Atrial Fibrillation
Atrial fibrillation (AF) has been the most frequently occurring, sustained arrhythmia, which causes significant morbidity and mortality. AF may not always be a totally random process.
- Trial name
- NCT05426603
- Testing
- Pulmonary vein isolation, Substrate ablation(PRISM based)
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Buddhist Tzu Chi General Hospital
Chronic Kidney Diseases
Prevalance Of Helicobacter Pylori Infection In Chonic Kidney Diseased Patient Admitted To Luxor Medical Complex
Detect prevalence of Helicobacter pylori infection in chronic kidney diseased patient admitted to Luxor medical complex and possible role of Helicobacter pylori in pathogenesis of chronic kidney diseased patient of unknown…
- Trial name
- NCT06371001
- Testing
- disease
- Volunteers
- 122 people
- Sponsor
- Assiut University
Premature Ventricular Contractions
Use of MIBG Scan Images in PVC Ablations
The purpose of this study is to assess if Single Photon Emission Computed Tomography (SPECT) demonstrating cardiac innervation can be integrated into current electrophysiology voltage mapping system and provide improved guidance…
- Trial name
- PVC-MIBG (NCT02279030)
- Testing
- MIBG nuclear scan
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Chronic Pancreatitis, Osteopenia
Bone Disease in Chronic Pancreatitis: A Complex Phenomenon
The purpose of this study is to define the prevalence of low bone density (osteopenia/osteoporosis) in patients with chronic pancreatitis.
- Conditions
- Chronic Pancreatitis, Osteopenia, Osteoporosis
- Trial name
- NCT02108509
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- University of Nebraska
Healthy, Hyperalgesia
Positron Emission Tomography to Measure Pain and Pain Control
This study will examine how the brain processes pain signals and how the different parts of the brain work with each other in response to painful stimuli.
- Conditions
- Healthy, Hyperalgesia, Pain, Peripheral Nervous System Disease
- Trial name
- NCT00001307
- Testing
- Oxygen-15 Water, Capsaicin
- Where
- United States
- Volunteers
- 273 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Neuralgia, Complex Regional Pain Syndromes
Novel Treatment Option for Neuropathic Pain
The purpose of this study is to determine whether the EGFR-inhibitor cetuximab is better than placebo for the treatment of neuropathic pain.
- Trial name
- NoTOPain (NCT02490436)
- Testing
- Cetuximab
- Where
- Norway
- Volunteers
- 15 people
- Sponsor
- Sorlandet Hospital HF
Heart Failure, Atrial Fibrillation
Cardiac Contractility Modulation in Patients With Chronic Heart Failure and the Various Forms of Atrial Fibrillation
Chronic heart failure (CHF) is a global pandemic which affects around 26 million people worldwide and develops in 10% of people over 70 years .
- Conditions
- Heart Failure, Atrial Fibrillation, Left Ventricular Ejection Fraction
- Trial name
- NCT05550792
- Testing
- optimizer smart
- Where
- Russia
- Volunteers
- 200 people
- Sponsor
- National Medical Research Center for Cardiology, Ministry of Health of Russian Federation
Diabetic Neuropathies
Role of Carnosine in Combination With Vitamin B Complex in Preventing the Progression of Diabetic Neuropathy in Type 2 Diabetes Patients
Evaluation of the influence of oral administration of carnosine in combination with vitamin B Complex in preventing the progression of diabetic neuropathy in type 2 diabetes patients.
- Trial name
- NCT05422352
- Testing
- Carnosine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Beni-Suef University
Heart Failure, Chronic Obstructive Pulmonary Disease
Effects of Remote Patient Monitoring on Chronic Disease Management
Remote patient monitoring is a potential component for the management of chronic conditions that may provide reliable and real-time physiological measurements for clinical decision support, alerting, and patient self-management.
- Conditions
- Heart Failure, Chronic Obstructive Pulmonary Disease, Chronic Kidney Disease, Uncontrolled Hypertension
- Trial name
- NCT03127852
- Testing
- Medly
- Where
- Canada
- Volunteers
- 96 people
- Sponsor
- University Health Network, Toronto
Premature Atrial Complex, Premature Ventricular Contraction
The Heart Rhythm Twins Study
Premature atrial contractions (PACs) and premature ventricular contractions (PVCs) are observed in the majority of individuals monitored for more than a few hours.
- Trial name
- NCT05866731
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Fistula Perianal
Human Placenta Mesenchymal Stem Cells Derived Exosomes Injection for Treatment of Complex Anal Fistula
The goal of this clinical trial is to learn if human placenta mesenchymal stem cells (MSC)-derived exosomes work to treat complex perianal fistula in adults without Crohn's disease.
- Trial name
- NCT06568653
- Testing
- exosome, routine conventional fistulotomy
- Volunteers
- 40 people
- Sponsor
- Tehran University of Medical Sciences
Atrial Premature Beats
To Evaluate the Efficacy and Safety of Wenxin Keli in Treating Atrial Premature Beats
A randomized, double-blind, two dose group, parallel-control multi-center, post-marketing clinical trial，to evaluate the efficacy and safety of Wenxin keli in treating atrial premature beats by different dose,to provide a…
- Trial name
- NCT02319603
- Testing
- Low dose WenXin keli, High dose WenXin keli
- Where
- China
- Volunteers
- 288 people
- Sponsor
- Beijing Bozhiyin T&S Co., Ltd.
Lymphedema of Upper Limb, Breast Cancer Lymphedema
Effect of Different Bandage Interface Pressures on Breast Cancer Related Lymphedema
The goal of this randomised comparison study is to compare different bandage interface pressures in individuals with breast cancer related lymphedema The main questions it aims to answer are: Is high or low bandage pressure…
- Conditions
- Lymphedema of Upper Limb, Breast Cancer Lymphedema, Edema Arm
- Trial name
- BCRL (NCT05660590)
- Testing
- complex decongestive physiotherapy with low pressure compression bandage, complex decongestive physiotherapy with high pressure compression bandage
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people
- Sponsor
- Abant Izzet Baysal University
Mitochondrial Myopathies, Mitochondrial Pathology
Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD)
SPIMD-301 is a 48-week, randomized, double-blind, parallel-group, placebo-controlled trial to assess efficacy and safety of single daily subcutaneous (SC) administration of elamipretide as a treatment for subjects with primary…
- Conditions
- Mitochondrial Myopathies, Mitochondrial Pathology, Mitochondrial DNA Mutation, Mitochondrial Diseases
- Trial name
- NuPower (NCT05162768)
- Testing
- Elamipretide
- Where
- 32 sites in United States, Australia and 8 more
- Volunteers
- 102 people
- Sponsor
- Stealth BioTherapeutics Inc.
Hair Thinning
Study Evaluating the Effects of Dietary Supplement on Hair Thickness and Hair Strength in Individuals With Self-Perceived Thinning Hair
The Nutra Harmony "Biotin, Collagen \& Keratin Beauty Complex" is an oral food/dietary supplement specifically designed to promote hair growth for people suffering from temporary thinning hair.
- Trial name
- NCT06605768
- Testing
- Complex with Biotin, Collagen, Keratin, Hyaluronic Acid.
- Where
- Ukraine
- Volunteers
- 80 people
- Sponsor
- Nutra Harmony LLC
Bladder Neoplasms
Mycobacterial Cell Wall-DNA Complex in Treatment of BCG-refractory Patients With Non-muscle Invasive Bladder Cancer
The purpose of this study is to determine the efficacy and safety of intravesical Mycobacterial Cell Wall-DNA Complex (MCC) in patients with non-muscle invasive transitional cell carcinoma (papillary tumors and/or carcinoma in…
- Trial name
- NCT00406068
- Testing
- Mycobacterial cell wall-DNA complex
- Where
- 31 sites in United States, Canada
- Volunteers
- 129 people
- Sponsor
- Bioniche Life Sciences Inc.
Atrial Fibrillation (AF), Tachycardia
Evaluation of a Test Algorithm for Use to Analyze ECG Data Collected From a Test Device of a 24-hour Simulated Use Period
The purpose of this study is to demonstrate that the ZywieAI analysis algorithm can be used to analyze ECG data collected from ZywieZ3 devices with non-traditional lead placement over a 24-hour simulated use period by human…
- Conditions
- Atrial Fibrillation (AF), Tachycardia, Bradycardia, PVC - Premature Ventricular Contraction
- Trial name
- NCT07188129
- Testing
- Test Algorithm and Test Device
- Where
- United States
- Volunteers
- 153 people
- Sponsor
- Zywie, Inc.