Clinical trials: Compliance
Health Attitude, Knowledge, Attitudes, Practice
Development and Pilot Test of a Postnatal mHealth Intervention - Phase 2
The goal of the study is to assess the feasibility and acceptability of the optimized MeSSSSage intervention which was developed and revised based on the results of our initial pilot testing.
- Conditions
- Health Attitude, Knowledge, Attitudes, Practice, Post Partum Depression, Acceptability of Health Care
- Trial name
- MESSAGE (NCT04693585)
- Testing
- MESSSSAGE - live, MESSSSAGE - asynchronous
- Where
- India
- Volunteers
- 201 people
- Sponsor
- University of California, San Francisco
Schizophrenia, Medication Nonadherence
Reducing the Burden of Chronic Psychotic Disorders in Tanzania (CAPACITY)
The proposed, three phase project will refine and test a first-ever care approach in SSA that combines LAI with a behavioral program specifically intended to promote medication adherence in chronic psychotic disorders (CPDs).
- Conditions
- Schizophrenia, Medication Nonadherence, Schizo Affective Disorder
- Trial name
- CAPACITY (NCT04327843)
- Testing
- Customized Adherence Enhancement, Haloperidol Decanoate
- Where
- Tanzania
- Volunteers
- 22 people
- Sponsor
- Case Western Reserve University
Heart Failure
Biventricular Pacing After Cardiopulmonary Bypass
The purpose of this study is to investigate the efficacy of optimized temporary biventricular pacing (BiVP) in patients undergoing open-heart surgery with preoperative LV dysfunction and an intraventricular conduction delay.
- Trial name
- BIPACS (NCT00498940)
- Testing
- Optimization Testing, Temporary Biventricular Pacing
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- Henry M. Spotnitz
Medication Adherence
Establishing Novel Antiretroviral Imaging for Hair to Elucidate Non-Adherence (ENLIGHTEN)
This is a pilot study to assess the feasibility, acceptability and appropriateness of delivery of the investigational "MedViewer" intervention in adult patients living with HIV who have been prescribed antiretroviral (ARV)…
- Trial name
- ENLIGHTEN (NCT04232540)
- Testing
- MedViewer report
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- University of North Carolina, Chapel Hill
Hypertension
Safety and Efficacy of Valsartan vs Atenolol and Hydrochlorothiazide Combination on Blood Flow in Hypertensive Patients
This study evaluated the effect of valsartan on small vessel blood flow in patients with mild-to-moderate hypertension in direct comparison to atenolol and hydrochlorothiazide.
- Trial name
- NCT00396656
- Testing
- Atenolol, Hydrochlorothiazide (HCTZ)), Valsartan
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 30 people
- Sponsor
- Novartis
Covid19, Vaccine Refusal
COVID-19 Vaccine Education at the Point of Testing to Increase Vaccine Uptake in Vulnerable Communities in SE Louisiana
This project is a 2-year study to investigate vaccine hesitancy and vaccine completion among vulnerable communities in the Southeastern Louisiana region.
- Conditions
- Covid19, Vaccine Refusal, Vaccine Hesitancy
- Trial name
- NCT04939506
- Testing
- COVID-19 Vaccine Education at the Point of COVID-19 Testing
- Where
- United States
- Volunteers
- 377 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Parkinson's Disease, Hyperprolactinemia
Study On Utilization Of Cabergoline For Compliance With Risk Minimization Activities (SUCRE)
The overall goal of this study will be to assess and monitor the adherence to and effectiveness of the new prescribing guidelines for cabergoline. Specific objectives will be to assess: 1.
- Trial name
- SUCRE (NCT01270711)
- Testing
- Study Drug
- Volunteers
- 22,014 people
- Sponsor
- Pfizer
Frailty, Frail Elderly Syndrome
Education for Prevention and Treatment of Frailty
Frailty is a condition with a high prevalence in older adults, leading to higher vulnerability and increasing the risk of adverse health outcomes and disabilities.
- Trial name
- FRAGSALUD (NCT05610605)
- Testing
- Health intervention programme: FRAGSALUD
- Where
- Spain
- Volunteers
- 235 people, healthy volunteers welcome
- Sponsor
- University of Cadiz
Fractures, Bone, Nausea and Vomiting, Postoperative
Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration
The aim of this study is to evaluate not only the occurrence of side effects, but the quality of the recovery (QoR-40 Questionnaire) of patients submitted to spinal anesthesia with administration of low doses (0.1 mg) of…
- Conditions
- Fractures, Bone, Nausea and Vomiting, Postoperative, Pruritus, Morphine Adverse Reaction
- Trial name
- NCT03035942
- Testing
- Dexamethasone, Ondansetron, Saline
- Where
- Brazil
- Volunteers
- 135 people
- Sponsor
- Pontificia Universidade Catolica de Sao Paulo
Health Attitude, Knowledge, Attitudes, Practice
Postnatal mHealth Intervention Development
This study is a six-week exploratory developmental phase (phase 1) of a larger project to develop an mHealth intervention targeting health education and social support for Indian women in the postnatal period.
- Conditions
- Health Attitude, Knowledge, Attitudes, Practice, Postpartum Depression, Acceptability of Health Care
- Trial name
- MESSAGE (NCT04636398)
- Testing
- MESSAGE - mHealth intervention
- Where
- India
- Volunteers
- 29 people
- Sponsor
- University of California, San Francisco
Patient Engagement, Community Integration
Creating a Clinic-Community Liaison Role in Primary Care: Engaging Patients and Community in Health Care Innovation
This project will engage patients and health care teams to develop, implement, and rigorously evaluate a new lay health worker role (Community Resource Specialist, CRS) for primary care teams.
- Trial name
- LINCC (NCT02286193)
- Testing
- Patient clinical encounters with Community Resource Specialist (CRS)
- Volunteers
- 418 people
- Sponsor
- Kaiser Permanente
Rheumatic Diseases, Gout
Medication Adherence Patterns in Rheumatic Diseases: A Behavioral Trial
Non-adherence to evidence-based prescription medications results in preventable morbidity and mortality for middle-aged and older adults.
- Conditions
- Rheumatic Diseases, Gout, Adherence, Medication, Lupus Erythematosus, Systemic
- Trial name
- NCT04776161
- Testing
- Cue-Reward Intervention, Cue-Reward Intervention with possible intensification
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Brigham and Women's Hospital
Sleep Initiation and Maintenance Disorders, Post-Traumatic Stress Disorders
Telemedicine Management of Chronic Insomnia
Insomnia is commonly present in Veterans with post-traumatic stress disorder (PTSD). Treatment of insomnia with a specialized type of psychotherapy has been shown to be more effective than treatment with medications.
- Trial name
- VIP (NCT01686438)
- Testing
- Cognitive behavioral therapy for insomnia
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- VA Office of Research and Development
Contraception, Contraceptive Usage
Contraception Navigator Program
The goal of this study is to pilot test the IN-Control Birth Control Navigator Program in Central Indiana for use by adolescents who would like to access birth control.
- Conditions
- Contraception, Contraceptive Usage, Health Care Utilization
- Trial name
- NCT05691270
- Testing
- IN-Control (Birth Control Navigator Program)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Indiana University
Chemo-radiation Induced Nausea and Vomiting
Rolapitant as an Antiemetic in Malignant Glioma Patients Receiving Radiotherapy and Temozolomide
The purpose of this phase 2 study is to assess the efficacy and patient satisfaction of oral rolapitant plus ondansetron vs. oral ondansetron monotherapy in malignant glioma (MG) patients receiving standard of care radiation (RT)…
- Trial name
- NCT02991456
- Testing
- Rolapitant, Ondansetron
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Duke University
HIV-1 Patients
Multicountry, Multicenter Post-Marketing Observational Study of Clinical, Biological and Virological Outcomes, Compliance and Tolerability of Kaletra® in Routine Clinical Use
KaleEAST is a non-interventional, post-marketing observational study (PMOS) in which lopinavir/ritonavir is prescribed in the usual manner in accordance with the terms of the local marketing authorization with regards to dose…
- Trial name
- KaleEAST (NCT01379703)
- Where
- 103 sites in Czechia, Georgia and 10 more
- Volunteers
- 2,288 people
- Sponsor
- Abbott
Cardiovascular Disease, Hypertension
Phase II Study of Heart Polypill Safety and Efficacy in Primary Prevention of Cardiovascular Disease
Cardiovascular is a major cause of mortality in Iran, accounting for 45.7% of deaths. In Golestan (North Eastern Iran) preliminary findings from follow-up of the Golestan Cohort are consistent with national figures: with 45% (at…
- Conditions
- Cardiovascular Disease, Hypertension, Hyperlipidemia, Heart Disease
- Trial name
- Polypill (NCT00603590)
- Testing
- Polypill
- Where
- Iran
- Volunteers
- 475 people, healthy volunteers welcome
- Sponsor
- Tehran University of Medical Sciences
Engagement, Patient
Enhancing Engagement With Digital Mental Health Care
This proposal is a partnership between Mental Health America (MHA), a nonprofit mental health advocacy and resource organization, Talkspace (TS), a for-profit, online digital psychotherapy organization, and the University of…
- Trial name
- NCT04507360
- Testing
- Study 1, Demographics Survey, Study 1, Next Steps Survey, Study 1, Generic Response
- Where
- 3 sites in United States
- Volunteers
- 78,390 people, healthy volunteers welcome
- Sponsor
- University of Washington
Anxiety, Stress
Virtual Reality Education Program to Reduce Anxiety During Radiation Therapy
The purpose of this study is to compare the efficacy of an immersive virtual reality (VR)-based education program with a form of patient education commonly provided by clinics (e.g., an educational video) at delivering education…
- Conditions
- Anxiety, Stress, Satisfaction, Patient, Preparedness
- Trial name
- NCT04029961
- Testing
- Video Education, VR-based Education
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Medical College of Wisconsin
Medication Adherence, Substance Abuse, Intravenous
A Randomized Trial of Vaccine Adherence in Young Injection Drug Users
The purpose of this study is to compare the effects of (a) immunization setting and (b) outreach worker support on young injection drug users' (IDU) adherence to a multiple dose immunization schedule with a combined hepatitis A…
- Conditions
- Medication Adherence, Substance Abuse, Intravenous, Risk Behavior, Hepatitis A
- Trial name
- UFO VAX (NCT00244374)
- Testing
- Hepatitis A & B vaccine, Outreach, AIC
- Where
- United States
- Volunteers
- 546 people
- Sponsor
- University of California, San Francisco