Clinical trials: Complication
Postoperative Pain, Acute
Comparison of the Effects of Tenoxicam and Paracetamol on Postoperative Pain
Postoperative pain is generally caused by inflammation and oedema related to tissue trauma. Surgical tissue trauma is caused by many factors such as cotery-related burns, surgical incisions, dissections, and instrumental…
- Trial name
- NCT05508451
- Testing
- Double jaw surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Postpartum Depression
Behavioral Change in the Mother-Infant Dyad: Preventing Postpartum Depression
Postpartum depression (PPD) is undertreated and the consequences of this are substantial for women and children. Studies show that infant cry/fuss and sleep behavior are associated with PPD, and that parenting interventions can…
- Trial name
- NCT01379781
- Testing
- Behavioral Intervention for PPD
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Infertility Female, Recurrent Miscarriage
Study on the Association Between SXCI and RM and the Possible Genetic Mechanism
To determine whether there is higher incidence of skewed X chromosome inactivation(SXCI) in the recurrent miscarriage(RM) population compared with normal population, and verify the existing hypothesis of the possible genetic…
- Trial name
- NCT02504281
- Where
- China
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Adhesions Pelvic, Adhesion; Uterus
Prediction of Vesicouterine Adhesions by Transvaginal Sonographic Sliding Sign Technique: a Validation Study
The aim of this study is to evaluate the predictive value of the real-time dynamic TVS sliding sign for vesicouterine pouch adhesions in women and to test the inter- and intraobserver agreement of this new technique.
- Conditions
- Adhesions Pelvic, Adhesion; Uterus, Adhesion; Bladder
- Trial name
- NCT05862155
- Where
- Netherlands
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Amsterdam UMC, location VUmc
Papillomavirus Infections
A Study of the Safety, Tolerability, and Immunogenicity of a 9-valent Human Papillomavirus Vaccine ([9vHPV]; V503) Administered to 9- to 15-Year-Old Japanese Girls (V503-008).
This study will evaluate the safety, tolerability, and immunogenicity of V503 in Japanese girls between the ages of 9 and 15 and will determine whether V503 induces an acceptable immune response to all human papillomavirus (HPV)…
- Trial name
- NCT01254643
- Testing
- V503
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Merck Sharp & Dohme LLC
Turner Syndrome, Cardiovascular Diseases
Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome
100 women with karyotype verified TS, previously examined at 4 study visits during a 19-year period will be asked to participate in a 5th study visit. Healthy age-matched females will be included as controls in a ratio 2:1.
- Conditions
- Turner Syndrome, Cardiovascular Diseases, Lymphedema, Inflammation
- Trial name
- TSCOR_V (NCT06325618)
- Testing
- No intervention other than obtaining biopsies, Indocyanine green (ICG)
- Where
- Denmark
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Prenatal Anxiety, Prenatal Depression
Effectiveness of an Online Biopsychosocial Intervention to Improve Well-being and Mental Health During Pregnancy
This study aims to develop and implement a preventive intervention through a mobile application to help pregnant women feel better emotionally and cope with the changes of pregnancy in a more positive way.
- Conditions
- Prenatal Anxiety, Prenatal Depression, Wellbeing, Obstetrical Complications
- Trial name
- BienGestar (NCT06871397)
- Testing
- Biopsychosocial Cognitive Behavioral Intervention
- Where
- Spain
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Chronic Kidney Diseases, Kidney Transplantation
MRI Technical Development and Applications in Kidney Disease
Magnetic resonance imaging (MRI), as a non-invasive and non-contrast enhanced technique, has the potential to improve patient health care and management. The overall objective of proposed project is to: 1.
- Conditions
- Chronic Kidney Diseases, Kidney Transplantation, Dialysis, Cognition Disorders
- Trial name
- NCT02421497
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Cardiovascular Diseases
Continuation of the nuMoM2b Heart Health Study
Cardiovascular disease (CVD) is the leading cause of mortality and morbidity in U.S. women at all ages, and large knowledge gaps exist in CVD predictive and preventative strategies for women.
- Trial name
- nuMoM2b-HHS2 (NCT05472597)
- Where
- 14 sites in United States
- Volunteers
- 4,048 people, healthy volunteers welcome
- Sponsor
- RTI International
Postoperative Complications
Saline Versus Lactated Ringer's Solution: The SOLAR Fluid Trial
Perioperative volumes of saline cause a mild acidosis compared with buffered fluids. On the other hand, saline administration maintains plasma osmolality and better repletes vascular volume which is an important goal of…
- Trial name
- NCT02565420
- Testing
- Normal saline, Lactated Ringer's solution
- Where
- United States
- Volunteers
- 8,616 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Polycystic Ovary Syndrome
Acupuncture for Polycystic Ovarian Syndrome
This is a randomized control trial of acupuncture for women with polycystic ovary syndrome. The study is triple-blinded.
- Trial name
- NCT00602940
- Testing
- Acupuncture
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Chronic Kidney Diseases, Healthy
Identification of P-cresyl Sulfate Producer Phenotype by Oral Tyrosine Challenge Test: Interactions Among Diet, Gut Microbiota, and Host Genome
Patients with chronic kidney disease (CKD) display a substantial increase in cardiovascular disease (CVD). Moreover, the prognosis of CVD in CKD is extremely poor.
- Trial name
- NCT04204174
- Testing
- Tyrosine, brand name: myprotein
- Where
- Taiwan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Postnatal Depression, Quality of Life
mHealth Intervention to Reduce Maternal Postnatal Depression and Promote Family Health
The proposed study is to test the effectiveness of a culturally-attuned, family-based mobile health (mHealth) intervention in reducing symptoms of postnatal depression and promoting health among expectant mothers in Hong Kong.
- Conditions
- Postnatal Depression, Quality of Life, Family Relations
- Trial name
- NCT05275413
- Testing
- family-based mHealth Intervention, mother-only mHealth Intervention, Health education
- Where
- 2 sites in Hong Kong
- Volunteers
- 1,578 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Stillbirth and Neonatal Mortality, Perinatal Mortality
Perinatal Mortality Outcomes Through Household Infection Pathways
The goal of this trial is to learn if replacing household soil floors with concrete floors can prevent deaths of infants around the time of birth, including stillbirths and deaths in the first month of life in rural Bangladesh.
- Conditions
- Stillbirth and Neonatal Mortality, Perinatal Mortality, Infant Mortality, Child Mortality
- Trial name
- POTH (NCT07620613)
- Testing
- Concrete household floor
- Where
- Bangladesh
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Stanford University
Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney
Effectiveness of Thread Embedding Acupuncture Analgesia at the EX-B2 Point Combined With Standard Therapy After Laparoscopic Living Donor Nephrectomy
Kidney transplantation is the main option besides hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) to prolong and improve the quality of life for patients with end-stage renal disease.
- Conditions
- Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney, Quality of Life, Acupuncture Analgesia
- Trial name
- NCT06197620
- Testing
- Thread embedding acupuncture and standard therapy
- Where
- Indonesia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Circumcision, Male
The Safety of Thermocautery Usage for Male Children's Circumcisions
Since circumcision is a significant workload for surgeons working at the rural state hospitals in Turkey, the use of circumcision techniques that are easy to implement and have low complications is becoming widespread.
- Trial name
- MC (NCT03305523)
- Testing
- Thermocautery
- Volunteers
- 1,780 people, healthy volunteers welcome
- Sponsor
- Kocatepe University
Focal Segmental Glomerulosclerosis, Nephrotic Syndrome
Genetic Causes of FSGS, Nephrotic Syndrome, or Kidney Failure
The investigators are trying to learn more about the cause of kidney diseases such as Focal Segmental Glomerulosclerosis (FSGS) and Nephrotic syndrome by studying genetics.
- Conditions
- Focal Segmental Glomerulosclerosis, Nephrotic Syndrome, End Stage Renal Disease, Kidney Failure
- Trial name
- FSGS (NCT02194582)
- Where
- United States
- Volunteers
- 2,050 people, healthy volunteers welcome
- Sponsor
- Beth Israel Deaconess Medical Center
Endometriosis
Research OutSmarts Endometriosis II Study
This product will be used as a diagnostic test to screen for the likelihood of endometriosis in menstruating adults with symptoms suggestive of endometriosis.
- Trial name
- ROSE2 (NCT05601596)
- Testing
- Analysis of menstrual blood to predict endometriosis
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Stillbirth
Revealed Versus Concealed Cerebroplacental Ratio
The purpose of this study is to evaluate the role of an integrated strategy at selecting fetuses for delivery at term based on a combination of fetal biometry and cerebroplacental ratio (CPR) to reduce stillbirth rate and adverse…
- Trial name
- NCT02907242
- Testing
- Revealment
- Where
- 9 sites in Chile, Czechia and 4 more
- Volunteers
- 11,582 people, healthy volunteers welcome
- Sponsor
- Hospital Clinic of Barcelona
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
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