Clinical trials: Complication
Preterm Delivery, Hypothermia
Randomized Controlled Trial of Social Network Targeting in Honduras
Social network targeting strategies can be used to improve the delivery and uptake of health interventions. We will enroll approximately 30,000 individuals into a randomized controlled trial of different targeting algorithms in…
- Conditions
- Preterm Delivery, Hypothermia, Diarrhea, Upper Respiratory Infection
- Trial name
- NCT02694679
- Testing
- CBNH
- Where
- 2 sites in United States, Honduras
- Volunteers
- 31,195 people, healthy volunteers welcome
- Sponsor
- Yale University
Intrauterine Adhesion
Safety of Leaving Cook Balloon Uterine Stent in Uterus for One Month
To use Cook balloon uterine stent to prevent intrauterine adhesion (IUA), and to see if leaving it in the uterus will cause uterine infection.
- Trial name
- NCT01167296
- Testing
- Cook balloon uterine stent
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Diabetes, Diabetic Retinopathy
Pivotal Trial of Automated Artificial Intelligence (AI) Based System for Early Diagnosis of Diabetic Retinopathy
In this pivotal trial, we aim to perform a prospective study to find the efficacy of iPredict-DR, an artificial intelligence (AI) based software tool on early diagnosis of Diabetic Retinopathy (DR) in the primary care and…
- Trial name
- NCT07151001
- Testing
- No intervention
- Where
- United States
- Volunteers
- 922 people, healthy volunteers welcome
- Sponsor
- iHealthScreen Inc
Ischemia Reperfusion Injury, Endothelial Function
The Metformin-FMD Trial
In acute myocardial infarction early restoration of coronary blood flow is the most effective strategy to limit infarct-size. Paradoxically, reperfusion itself also aggravates myocardial injury and contributes to final infarct…
- Trial name
- MetFMD (NCT01610401)
- Testing
- Metformin, Pretreatment with metformin in combination of infusion of caffeine., No pretreatment with metformin in combination with infusion of caffeine
- Where
- Netherlands
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Cervical Cancer
Increasing Attendance to Cervical Cancer-screening Among Immigrants
Although health-related interventions should become increasingly diversity-sensitive, there will always be a need of adapting specific interventions to some immigrant populations.
- Trial name
- NCT03155581
- Testing
- User intervention, Health professional intervention
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of Bergen
Hypertension in Pregnancy, Diabetes Mellitus in Pregnancy
Insulin Resistance and Hypertensive Disorders in Pregnancy
The purpose of this study is to determine whether insulin resistance might affect the pathogenesis of hypertensive disorders in pregnancy since midtrimester.
- Trial name
- NCT00412230
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Messina
Postoperative Pain, Regional Anesthesia
Comparison of Continuous Fascia Iliaca Compartment Block With Continuous PENG Block in Total Hip Replacement Cases
Adequate pain management after total hip arthroplasty (THA) is crucial for early ambulation and patient satisfaction. However, due to the hip joint's innervation complexity, the optimal regional analgesia technique for THA…
- Conditions
- Postoperative Pain, Regional Anesthesia, Pain Management, Total Hip Arthroplasty
- Trial name
- PENG (NCT06806865)
- Testing
- Periarticular nerve group block (PENG), Continuous supra-inguinal fascia iliaca compartment block (SIFICB)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Adolescent Dysmenorrhea
Adolescent Dysmenorrhea : Prevalence, Severity, Experience and Management in the Use of Medication in High School Girls in Ille-et-Vilaine
Dysmenorrhea or painful menstruation is a common symptom of menses. Dysmenorrhea is defined as a painful, cramping sensation in the lower abdomen or back associated with menstrual periods and is classified into primary and…
- Trial name
- DAPsvs (NCT04007471)
- Testing
- Anonymous survey
- Where
- France
- Volunteers
- 979 people, healthy volunteers welcome
- Sponsor
- Rennes University Hospital
Endometriosis, Infertility
Harnessing the Disease Signatures From Endometrium and Menstrual Blood to Identify Avenues for the Treatment of Chronic Conditions Such as Endometriosis and Related Pathologies: This is an Observational Study Aimed at Shedding Light on Women's Health
Many women's health conditions have limited treatments available and poor outcomes, in part due to the lack of understanding of disease processes and lack of data available.
- Conditions
- Endometriosis, Infertility, Endometrial Cancer, Adenomyosis, Endometriosis
- Trial name
- CYCLE_ENDO (NCT06990971)
- Testing
- No Intervention: Observational Cohort
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Cycle Therapeutics Ltd
Short Bowel Syndrome
Safety and Immunogenicity of Rotavirus Vaccine (RotaTeq(R)) in Infants With Short Bowel Syndrome
Rotavirus infection is a common pediatric illness and is the leading cause of severe acute gastroenteritis (vomiting and diarrhea) in infants and young children.
- Trial name
- NCT00767364
- Testing
- Oral, live, pentavalent rotavirus vaccine; RotaTeq(R)
- Where
- 3 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Michigan
Gestational Diabetes Mellitus
The Role of Pregnancy-induced Gallbladder Dysmotility in the Pathophysiology of Gestational Diabetes Mellitus
The primary aim of the study is to evaluate postprandial gallbladder emptying and plasma concentrations of the glucose-lowering and satiety-promoting gut hormone glucagon-like peptide 1 (GLP-1) during third trimester of pregnancy…
- Trial name
- NCT04108065
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gentofte, Copenhagen
Kidney Stones, Urolithiasis, Hypocitraturia, Living Kidney Donation
Long-Term Risk of Kidney Stones in Living Kidney Donors
Using a population-based, matched, retrospective cohort approach, this study will evaluate the long-term risk of kidney stones among living kidney donors compared with matched healthy nondonors.
- Conditions
- Kidney Stones, Urolithiasis, Hypocitraturia, Living Kidney Donation, Living Kidney Donor
- Trial name
- NCT07611500
- Testing
- Living kidney donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Breast Carcinoma, Cervical Carcinoma
The Ohio State University (OSU) SCREEN Community Program
This clinical trial develops and tests how well a multi-level intervention (MLI), The Ohio State University (OSU) SCREEN Community Program, works to increase screening and follow-up for breast, cervical and colorectal (CRC)…
- Conditions
- Breast Carcinoma, Cervical Carcinoma, Colorectal Carcinoma
- Trial name
- NCT06666192
- Testing
- Cancer Screening, Discussion, Educational Activity
- Where
- United States
- Volunteers
- 2,067 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Pain, Postoperative
Does a ThoracoLumbar Interfacial Plane (TLIP) Block With Liposomal Bupivacaine Provide TLIP Block in Spinal Surgery
The investigators are looking to recruit patients into a study demonstrating the effectiveness of a superficial nerve block involving the thoracolumbar interfascial plane (TLIP) in reducing postoperative pain in those undergoing…
- Trial name
- NCT04865211
- Testing
- Liposomal bupivacaine, Bupivacaine Injection
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cooper Norcross Health
Overactive Bladder (OAB)
Vaginal CO2 Laser in Postmenopausal Women With Overactive Bladder Syndrome (OAB)
This study evaluates the clinical efficacy and symptom relief of vaginal fractional CO2 laser treatment in post-menopausal women with Overactive Bladder syndrome(OAB).
- Trial name
- NCT03846895
- Testing
- Microablative Fractional CO2 laser
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Breast Cancer, Colo-rectal Cancer
The French E3N Prospective Cohort Study
The French E3N cohort was initiated in 1990 to investigate the risk factors associated with cancer and other major non-communicable diseases in women.
- Conditions
- Breast Cancer, Colo-rectal Cancer, Parkinson Disease, Asthma
- Trial name
- E3N (NCT03285230)
- Where
- France
- Volunteers
- 100,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Heart Arrest, Cardiac Arrest
Resuscitation Outcomes in the Netherlands
The Resuscitation Outcomes in the Netherlands - study assesses one-year survival and quality of life after In-Hospital Cardiac Arrest(IHCA).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiac Arrest as A Complication of Care, Outcome, Fatal
- Trial name
- ROUTiNE (NCT03120507)
- Where
- 12 sites in Netherlands
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Erasmus Medical Center
Amniotic Fluid Embolism, Pulmonary Hypertension
Effect of Tourniquet Binding of Cervical on the Blood Volume of Amniotic Fluid in Cesarean Section
This study was conducted to investigate whether the use of tourniquet after delivery of the fetus could reduce the amount of amniotic fluid entering the bloodstream and thus reduce the incidence of intraoperative adverse events.
- Trial name
- NCT06254092
- Testing
- tourniquet binding of cervical
- Where
- China
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Healthy Volunteers
A Phase I Study Comparing the Safety, Pharmacokinetics and Renal Effects of VRP-034 and Marketed Polymyxin B in Healthy Volunteers
This is a Phase 1, single-center, randomized, double-blind, active-controlled clinical study designed to evaluate the safety, tolerability, pharmacokinetics (PK), and nephrotoxicity attenuation potential of VRP-034 compared with…
- Trial name
- VRP-034 (NCT07502144)
- Testing
- VRP-034 (Polymyxin B 500,000 IU), Commercially available Polymyxin B 500,000 IU (Poly-MxB)
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Venus Remedies Limited
Postoperative Delirium, Strabismus
Does Preoperative Sleep Quality Affect the Postoperative Emergence Delirium in Children Undergoing Strabismus Surgery
Sleep is important in maintaining the physiological function of the human body. Recently several studies have reported that preoperative sleep quality is associated with postoperative emergence delirium (ED) The ED is a common in…
- Conditions
- Postoperative Delirium, Strabismus, Sleep Disorder
- Trial name
- NCT03332407
- Where
- South Korea
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Pusan National University Hospital
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