Clinical trials: Complication
Postoperative Pain
Transversus Abdominis Plane Block Versus Paravertebral Block for Post Operative Pain Relief in Open Renal Surgeries
Pain relief after renal surgeries is essential as it may lead to reduction in the incidence of many post operative complications .
- Trial name
- NCT04697420
- Testing
- Thoracic paravertebral block, Transversus abdominis plane block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hyperandrogenism, Polycystic Ovary Syndrome
Does Spironolactone Normalize Sleep-wake Luteinizing Hormone Pulse Frequency in Pubertal Girls With Hyperandrogenism?
The purpose of this study is to determine if, in mid- to late pubertal girls with hyperandrogenism (HA), androgen-receptor blockade (spironolactone) alone normalizes sleep-wake luteinizing hormone (LH) pulse frequency (primary…
- Conditions
- Hyperandrogenism, Polycystic Ovary Syndrome, Puberty
- Trial name
- CBS010 (NCT04723862)
- Testing
- Spironolactone
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Bacterial Vaginosis
Effect of Different Courses of Lactobacilli Treatment on Bacterial Vaginosis and Pregnancy Outcomes
The purpose of this study is to examine the effect of lactobacillus preparation on Bacterial vaginosis (BV) in low-risk pregnant women and to evaluate the value of double courses for the patients with durative positive result.
- Trial name
- BV (NCT01421615)
- Testing
- Vaginal capsules of lactobacilli
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine
Postoperative Complications
Total Intravenous Anesthesia and Inhalation Anesthesia
The aim of us is to define the incidence of postoperative complications and recovery time in view of two anesthesia procedures. During the period between 01.01.2016 and 01.01.2017, totally 583 patients were included in the study…
- Trial name
- NCT03187717
- Volunteers
- 583 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Female Infertility
Effect of Growth Hormone on Uterine Receptivity in Women With RIF in an Oocyte Donation Program
105 infertile women are enrolled in the randomized controlled trial: 70 women with a history of RIF with donated oocytes and 35 infertile women undergoing the first oocyte donation attempt.
- Trial name
- NCT03237117
- Testing
- Growth Hormone (GH)
- Where
- Spain
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Competence Centre on Health Technologies
Chronic Kidney Disease
A Study to Evaluate the Safety and Pharmacokinetics With MEDI8367 Administered in Healthy Subjects, and in Subjects With Chronic Kidney Disease
This Phase I First in Human (FIH) study is being conducted to determine the safety, pharmacokinetics (PK), pharmacodynamics (PD), and immunogenicity profile of MEDI8367 across the dose range.
- Trial name
- NCT04365218
- Testing
- MEDI8367
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Postoperative Nausea, Vomiting
Postoperative Nausea and Vomiting in Laparoscopic Abdominal Surgery
The goal of this clinical trial is to compare frequency with postoperative nausea and vomiting in ASA( American Society of Anesthesiologists) I, II patients undergoing laparoscopic surgery.
- Trial name
- PONV (NCT05632224)
- Testing
- Aprepitant, Granisetron
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Baskent University
Liver Transplant; Complications, Cirrhosis
Technology Enabled Strategies to Promote Treatment Adherence in Liver Transplant
Liver transplantation is increasingly performed for older adults with multiple comorbidities. Medication adherence is key to maintaining proper function of the transplanted liver and optimize health; however, adhering to…
- Conditions
- Liver Transplant; Complications, Cirrhosis, End Stage Liver DIsease, Medication Adherence
- Trial name
- TEST (NCT05260268)
- Testing
- TEST Intervention
- Where
- 3 sites in United States
- Volunteers
- 361 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Delirium
Standardization of a Novel Self-administered Tablet Computer-based Clinical Screening Tool for Adverse Postoperative Cognitive Outcomes
Postoperative delirium (POD) and postoperative cognitive dysfunction (POCD) are common complications after surgery and may affect elderly patients in particular.
- Trial name
- CogCheck-Norm (NCT02708823)
- Testing
- CogCheck application
- Where
- Switzerland
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- Nicolai Goettel
Healthy Participants
A Study to Investigate the Safety, Tolerability and Pharmacodynamics of AZD4144 in Participants With Obesity
The aim of this study is to evaluate the safety and tolerability, and pharmacodynamics (PD) of AZD4144 administered as repeated daily oral dosing.
- Trial name
- NCT06942923
- Testing
- AZD4144
- Where
- Germany
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Breastfeeding, Quality of Life
The Effectiveness of Proactive Telephone Support Provided to Breastfeeding Mothers of Preterm Infants
Although breast milk has numerous benefits for infants' development, with heightened effects in those born preterm (at < 37 gestational weeks), mothers of preterm infants have shorter breastfeeding duration than mothers of term…
- Conditions
- Breastfeeding, Quality of Life, Parental Stress, Attachment
- Trial name
- NCT01806480
- Testing
- Person-centred proactive breastfeeding telephone support
- Where
- 6 sites in Sweden
- Volunteers
- 493 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Renal Insufficiency
A Study of Epetraborole Tablets in Subjects With Degrees of Renal Function
This is a Phase 1 study to evaluate the pharmacokinetics (PK), safety and tolerability of epetraborole tablets in adult subjects with normal renal function, subjects with various degrees of renal impairment, and subjects with…
- Trial name
- NCT05283746
- Testing
- Epetraborole
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- AN2 Therapeutics, Inc
Preterm Birth, Preterm Labor
Is the Vaginal Microbiome and Metabolome Associated With Spontaneous Preterm Birth (sPTB) in Multiple Pregnancies?
The aim of this study is to try and find links between the microscopic organisms (such as bacteria, yeasts and viruses) in the vagina, and twin pregnancies that deliver too early (preterm birth).
- Conditions
- Preterm Birth, Preterm Labor, Multiple; Pregnancy, Complicated, Twin Dichorionic Diamniotic Placenta
- Trial name
- SPRUCE (NCT06053697)
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Liverpool
Preterm Labor
Impact of Suspected Preterm Labour on Cardiometabolic Profile and Neurodevelopment
Suspected preterm labour (SPL), define as the presence of regular and painful uterine contractions and cervical shortening, constitute a prenatal insult with potential long-term consequences.
- Trial name
- SKs (NCT05211297)
- Where
- Spain
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Depression, Postpartum, Maternal Behavior
The Effect of Baby Massage on Postpartum Depression and Maternal Attachment
This study was conducted to determine the effect of baby massage on postpartum depression and maternal attachment in the postpartum period.
- Conditions
- Depression, Postpartum, Maternal Behavior, Attachment
- Trial name
- NCT05813782
- Testing
- Baby Massage
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Endometriosis
Open Label Immunotherapy of Endometriosis
Endometriosis is a chronic gynecological disease characterized by sustained painful symptoms that are responsible for a decline in the quality of life of sufferers.
- Trial name
- NCT03340324
- Testing
- V-Endo
- Where
- Mongolia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Immunitor LLC
Obstetric Labor, Premature
Vaginal Indomethacin for Preterm Labor
Indometacin is a cyclooxygenase agent from the NSAID family that has been used to treat preterm contractions since the 70's by preventing the synthesis of prostaglandins.
- Trial name
- TOCOMED (NCT04404686)
- Testing
- Indomethacin, Nifedipine
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Stress Urinary Incontinence
Effect of Coping Training on Attitudes, Sleep, and Quality of Life in Women With Stress Urinary Incontinence
This study aims to examine the effects of urinary incontinence management training provided to postmenopausal women on their urinary incontinence attitudes, sleep, and quality of life.
- Trial name
- NCT07126080
- Testing
- Incontinence Coping Training
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Postoperative Pain, Cesarean Section
Effects of Nerve Blocks on Pain After Caesarean Section and Postpartum Depression
At the end of your cesarean section surgery, which is started by applying medication to the spinal cavity from your waist, pain medication will be applied between the relevant muscle and its covering from your lower abdomen or…
- Conditions
- Postoperative Pain, Cesarean Section, Postpartum Depression
- Trial name
- NCT06221280
- Testing
- Nerve block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Hemodialysis Complication
Difference Between Interval and Continous Intradialytic Exercise on Functional Capacity in Hemodialysis Patient
The goal of this study is to find out the effect of interval versus continous intradialytic training on muscle quality index and functional capacity in Hemodialysis patients.
- Trial name
- NCT05722496
- Testing
- Aerobic pedaling exercise
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
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