Clinical trials: Complication of Dialysis
Chronic Renal Failure, Chronic Kidney Disease
Safety & Efficacy of EPO-018B for the Treatment of Anemia in Participants With Chronic Kidney Diseases Not on Dialysis
The purpose of this study is to evaluate the safety,efficacy， pharmacodynamics (PD), and pharmacokinetics (PK) of multiple intravenous doses of EPO-018B in participants with chronic kidney disease (CKD) Who are not on dialysis
- Conditions
- Chronic Renal Failure, Chronic Kidney Disease, Anemia
- Trial name
- NCT02403362
- Testing
- EPO-018B
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Jiangsu Hansoh Pharmaceutical Co., Ltd.
Kidney Disease
Repeat Dose Safety and Efficacy Study for Compound to Treat Anemia
The purpose of this study is to characterize the safety and efficacy of repeat doses of compound 1278863A in subjects with anemia.
- Trial name
- NCT01047397
- Testing
- 1278863A
- Where
- 37 sites in Australia, India and 2 more
- Volunteers
- 107 people
- Sponsor
- GlaxoSmithKline
Cannabis, Chronic Kidney Diseases
The Pharmacokinetics of Single Dose Oral Tetrahydrocannabinol and Cannabidiol
POT-GFR-PK is a single dose pharmacokinetic study oral tetrahydrocannabinol (THC) and cannabidiol (CBD) in healthy adult controls and individuals with chronic kidney disease including those treated with in-center hemodialysis.
- Conditions
- Cannabis, Chronic Kidney Diseases, Dialysis
- Trial name
- POT-GFR-PK (NCT05742724)
- Testing
- Tetrahydrocannabinol-Cannabidiol Combination
- Where
- Canada
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- McMaster University
End Stage Renal Disease
Pharmacokinetics, Safety and Tolerability of Aliskiren (SPP100) in Patients With End Stage Renal Disease on Hemodialysis and Matched Healthy Subjects
This study will assess the pharmacokinetics, safety and tolerability of aliskiren in healthy subjects and patients with End Stage Renal Disease on hemodialysis.
- Trial name
- NCT01568775
- Testing
- Aliskiren
- Where
- Germany
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Novartis
Hyperphosphatemia, Anemia, Iron Deficiency
Auryxia (Ferric Citrate) Therapy for In-Center and Home Dialysis Participants
This study is being conducted to demonstrate the effect of Auryxia, when used as the primary phosphate lowering therapy, on the overall cumulative use of erythropoiesis-stimulating agent and intravenous iron as well as on the…
- Conditions
- Hyperphosphatemia, Anemia, Iron Deficiency, Renal Insufficiency
- Trial name
- IMPACT (NCT04922645)
- Testing
- Ferric Citrate 1 gram Oral Tablet, Standard of care phosphate-lowering therapy
- Where
- 13 sites in United States
- Volunteers
- 214 people
- Sponsor
- USRC Kidney Research
Renal Anemia
A Randomized Study of the Safety and Efficacy of FG-2216 in Subjects With Renal Anemia Not Requiring Dialysis and Not Receiving Recombinant Human Erythropoietin
The purpose of this study is to test the safety and efficacy of FG-2216 in the treatment of patients with renal anemia who are not receiving erythropoietin and who are not on dialysis.
- Trial name
- NCT00456053
- Testing
- FG2216
- Where
- 27 sites in United States
- Volunteers
- 145 people
- Sponsor
- Kyntra Bio
Insulin Resistance, Diabetes
Insulin Resistance And End Stage Renal Disease: The Role Of Retinol Binding Protein 4
The purpose of this study is to determine whether Retinol binding protein 4 has a role in insulin resistance development in patients suffering from end stage renal disease on hemodialysis.
- Conditions
- Insulin Resistance, Diabetes, End Stage Renal Disease
- Trial name
- NCT00910130
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Chronic Kidney Failure, End-Stage Kidney Disease
Traditional Chinese Medicine (TCM) Colon Dialysis Treats Non-dialysis End-Stage Kidney Disease
This study evaluates the clinical efficacy and study the therapeutic mechanism of a kind of traditional Chinese medicine colonic dialysis on Chronic kidney disease (CKD) 5 without blood dialysis therapy in adults.
- Trial name
- NCT03142529
- Testing
- colon lotion
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Pang Peng
End Stage Renal Disease
High-cutoff Hemodialyzer to Reduce Chronic Inflammation in Hemodialysis Patients
The purpose of this study is to test whether a dialyzer with a higher than usual permeability for proteins can eliminate proinflammatory proteins from the blood of patients on regular maintenance hemodialysis who have chronically…
- Trial name
- HCO1100 (NCT00974779)
- Testing
- HCO1100 dialyzer, regular dialysis polyamide
- Where
- Germany
- Volunteers
- 19 people
- Sponsor
- Martin-Luther-Universität Halle-Wittenberg
Chronic Kidney Diseases, End Stage Renal Disease on Dialysis
A Study of Wrist Worn Accelerometers in End-Stage Renal Disease
The kidneys are important at getting rid of toxins and excess water from the body. If they fail, then toxins and excess water builds up within the body.
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease on Dialysis, Frailty
- Trial name
- W-WARD (NCT04860440)
- Testing
- GeneActiv wrist worn accelerometer
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
End Stage Renal Disease, Dialysis Related Complication
Comparison of Hemodialysis With Medium Cut-off Dialyzer (Theranova) and High Flux Dialyzer
The aim of this study is to evaluate the removal of midle molecules and inflammatory cytokines with the Theranova-500 ™ dialyzer (medium cut-off membrane, Baxter®) versus a high flux dialyzer Elisio-21H ™ (High-flux membrane…
- Conditions
- End Stage Renal Disease, Dialysis Related Complication, Dialysis Amyloidosis
- Trial name
- THERANOVA (NCT03211676)
- Testing
- Theranova-500 dialyzer, Elisio-21H
- Where
- France
- Volunteers
- 49 people
- Sponsor
- Poitiers University Hospital
ESRD, Hemodialysis
The Evaluation of the DIMI RRT System In-Center to Demonstrate Safety and Usability in the Home Environment
This is a prospective, multicenter, open label, non-randomized, cross-over study. Subjects will be enrolled in the trial for approximately 18 weeks and will use the DIMI RRT System for their dialysis treatments for all study…
- Trial name
- NCT04868643
- Testing
- The DIMI Renal Replacement Therapy (RRT) System
- Sponsor
- Dialco Medical Inc.
Kidney Failure, Chronic
A Study in Participants With End-Stage Renal Disease
The purpose of this trial is to explore the effect of LY2127399 on those antibodies that are a barrier to kidney transplant. Transplantation is currently the definitive treatment for End-Stage Renal Disease (ESRD), providing…
- Trial name
- NCT01200290
- Testing
- LY2127399
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Eli Lilly and Company
Chronic Kidney Disease, Dialysis
The KidneyCARE (Community Access to Research Equity) Study
For chronic kidney disease (CKD), there is a lack of unique and powerful platform for patient engagement, research studies and public health advocacy work.
- Conditions
- Chronic Kidney Disease, Dialysis, Kidney Transplant
- Trial name
- NCT05497518
- Testing
- Observational study - registry
- Where
- United States
- Volunteers
- 50,000 people
- Sponsor
- Tufts Medical Center
End Stage Renal Disease, Chronic Kidney Disease
More Frequent Dialysis (>3 Treatments Per Week)
The study compares the benefits of short daily hemodialysis six days a week, nocturnal (night time) hemodialysis six days a week, every other day and every other night hemodialysis to traditional three days a week…
- Trial name
- MFD (NCT00575497)
- Testing
- More frequent hemodialysis, Conventional Hemodialysis
- Where
- 2 sites in United States
- Volunteers
- 46 people
- Sponsor
- Satellite Healthcare
End Stage Renal Disease, Hypotension During Dialysis
Effect of Protein Intake During Hemodialysis on Blood Pressure and Arterial Stiffness Indices
Open label, randomized, cross-over clinical study comparing the acute effect of high versus low protein meals during dialysis on intradialytic blood pressure, 24-hour ambulatory blood pressure and arterial stiffness indices on…
- Conditions
- End Stage Renal Disease, Hypotension During Dialysis, Protein Malnutrition, Arterial Sclerosis
- Trial name
- NCT03947710
- Testing
- High-protein meals, Low- protein meals, No meals
- Where
- Greece
- Volunteers
- 45 people
- Sponsor
- Aristotle University Of Thessaloniki
End Stage Renal Disease
Fluid Overload in Peritoneal Dialysis
The objective of this study is to determine the effectiveness of treating peritoneal dialysis (PD) patients with fluid overload by a structured nurse-lead intervention protocol.
- Trial name
- NCT02557347
- Testing
- Aggressive fluid management
- Where
- Hong Kong
- Volunteers
- 102 people
- Sponsor
- Chinese University of Hong Kong
End-stage Renal Disease
The Effect of Fructose on Blood Fats in Dialysis Patients and Healthy Volunteers
This study will evaluate how a common dietary sugar (fructose) raises blood fats (triglycerides). We will determine whether the production of fat from fructose is higher in dialysis patients compared to healthy volunteers.
- Trial name
- NCT00234156
- Testing
- oral fructose and high fat diet
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rockefeller University
Chronic Kidney Disease Requiring Chronic Dialysis
Evaluation of Routinely Measured Patient-reported Outcomes in Hemodialysis Care
Patient-reported outcome measures (PROMs) are reports coming directly from patients about how they function or feel in relation to a health condition and its therapy, without interpretation of the patient's responses by a…
- Trial name
- EMPATHY (NCT03535922)
- Testing
- PROMs Assessment
- Where
- 3 sites in Canada
- Volunteers
- 3,977 people
- Sponsor
- University of Alberta
IgAN - IgA Nephropathy
Assessing the Global Burden of IgA Nephropathy (IgAN) in Patients Receiving Hemodialysis: A Real-World Study Using DOPPS Data
This study leverages the global Dialysis Outcomes and Practice Patterns Study (DOPPS) database to generate real-world evidence on the burden of IgAN in patients who progress to kidney failure and require maintenance hemodialysis…
- Trial name
- NCT07607002
- Volunteers
- 70,000 people
- Sponsor
- Arbor Research Collaborative for Health
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.