Clinical trials: Complication of Hemodialysis
Renal Failure
Preemptive Treatment With Grazoprevir and Elbasvir for Donor HCV Positive to Recipient HCV Negative Kidney Transplant
Proof of concept, open-label single center study for the donation of HCV positive kidneys to HCV negative patients, with preemptive, interventional treatment to prevent HCV transmission upon transplantation.
- Trial name
- NCT02945150
- Testing
- elbasvir (50mg) / grazoprevir (100mg) (fixed dose combination)
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Massachusetts General Hospital
Hyperphosphatemia, End-stage Renal Disease
Study of Individualized Therapy on Hyperphosphatemia in Maintenance Hemodialysis Patients
This study is designed to study and compare the efficacy and cost-effectiveness of individualized phosphate-lowering therapy in comparison with regular guideline-recommended therapy.
- Trial name
- NCT02684643
- Testing
- enhanced individualised therapy, non-enhanced individualised therapy, regular intervention
- Where
- China
- Volunteers
- 72 people
- Sponsor
- Huashan Hospital
Chronic Kidney Disease, End-stage Renal Disease
Home-based Exercise in Chronic Kidney Disease
A home-based exercise program will be implemented in three different groups of participants: advanced chronic kidney disease, end-stage renal disease in substitutive treatment hemodialysis or peritoneal dialysis.
- Trial name
- HBCKD-BCN (NCT03621176)
- Testing
- Home-based exercise
- Where
- Spain
- Volunteers
- 57 people
- Sponsor
- Cardenal Herrera University
Renal Impairment
A Study to Evaluate the Drug Levels of Mezigdomide in Adult Participants With Renal Impairment
The purpose of this study is to evaluate the drug levels of mezigdomide in participants with renal impairment.
- Trial name
- NCT06318676
- Testing
- Mezigdomide
- Where
- 3 sites in United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Celgene
Uremia, Uremic Osteodystrophy
Multi-center Clinical Study on Hemoperfusion of KHA80
To evaluate the decreasing rate of blood IL-6, β2-MG and PTH in maintenance hemodialysis patients in the 52nd week compared with routine hemodialysis.
- Conditions
- Uremia, Uremic Osteodystrophy, Dialysis Related Complication
- Trial name
- NCT06233838
- Testing
- KHA80 hemoperfusion treatment
- Where
- China
- Volunteers
- 394 people
- Sponsor
- First Affiliated Hospital of Fujian Medical University
ESRD (End-Stage Renal Disease), Maintenance Hemodialysis
Efficacy of pHA130 Hemoadsorption on Protein-Bound Uremic Toxins and Quality of Life in Kidney Failure
Patients on maintenance hemodialysis (MHD) face a high risk of cardiovascular mortality and reduced quality of life. Conventional high-flux hemodialysis (HD) is the standard of care but has limited efficacy in clearing…
- Trial name
- PHOENIX (NCT07656168)
- Testing
- pHA130 Hemoadsorption Cartridge, High-flux Hemodialyzer
- Where
- China
- Volunteers
- 100 people
- Sponsor
- China-Japan Friendship Hospital
End Stage Renal Disease
Choice Sets for Advance Directives
There is a large gap between the care seriously ill patients want and the care they receive. Advance directives (ADs) offer an opportunity for patients to express specific end-of-life preferences to avoid unwanted care.
- Trial name
- NCT02209038
- Testing
- Expanded AD Choice, Expanded Life-sustaining Therapy Choice
- Where
- 15 sites in United States
- Volunteers
- 321 people
- Sponsor
- University of Pennsylvania
End-stage Renal Disease (ESRD)
Hierarchical Management for Maintenance Hemodialysis Patients
This prospective, randomized controlled trial investigates the effectiveness of a nurse-led, Triangle Hierarchical Management model compared to routine care for patients on maintenance hemodialysis.
- Trial name
- NCT07123168
- Testing
- Triangle Hierarchical Management, routine care
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Yanyan Deng
Nephrology
Efficacy of Epoetin Alfa Deep Tank in Treatment of Anemia in Patients With Chronic Kidney Disease Receiving Hemodialysis
The purpose of this study is to evaluate whether the efficacy of Epoetin alfa DT is equivalent to that of Epoetin alfa RB for the treatment of anemia in patients with CKD receiving hemodialysis
- Trial name
- NCT00146224
- Testing
- Epoetin alfa RB, Epoetin alfa DT
- Volunteers
- 420 people
- Sponsor
- Amgen
Hemodialysis, Thromboinflammation
Effect of Modifying Magnesium Concentration in Citrate-enriched Dialysate on Hemodialysis-associated Thromboinflammation
This clinical trial investigates whether the composition of dialysate influences hemodialysis-associated thromboinflammation. Specifically, it evaluates the effects of magnesium concentration and acid type in dialysate on immune…
- Conditions
- Hemodialysis, Thromboinflammation, Hemodialysis Complication, End Stage Renal Disease (ESRD)
- Trial name
- pilot OMAGOD + (NCT07206524)
- Testing
- Hemodialysis using dialysate containing citric acid and magnesium at a concentration of 1.0 mmol/L, Hemodialysis using acetic acid dialysate with magnesium 0.5 mmol/L, Hemodialysis using citric acid dialysate with magnesium 0.75 mmol/L
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Universitair Ziekenhuis Brussel
End-stage Renal Disease (ESRD)
A Study of Safety, PK, & PD of ISIS 416858 Administered Subcutaneously to Patients With End-Stage Renal Disease on Hemodialysis
Evaluation of safety, tolerability, PK and PD of ISIS 416858 in patients with end-stage renal disease (ESRD) receiving chronic hemodialysis.
- Trial name
- NCT02553889
- Testing
- ISIS 416858
- Where
- 8 sites in Canada
- Volunteers
- 49 people
- Sponsor
- Ionis Pharmaceuticals, Inc.
End-Stage Renal Disease, Hemodialysis Complication
The Effect of Home-based Exercise on Postural Abnormalities
This study evaluates the effects of synchronous home-based tele-exercise on postural abnormalities (FHP and hyper-kyphosis) in dialysis patients.
- Trial name
- NCT06877962
- Testing
- Home-based Tele Exercise
- Where
- Iran
- Volunteers
- 30 people
- Sponsor
- Pardis Specialized Wellness Institute
End-Stage Renal Disease
Mode of Dialysis Therapy and Outcomes in End Stage Renal Disease (ESRD)
The purpose of this study is: 1. to compare complications and mortality of hemodialysis with those of peritoneal dialysis in Korean end stage renal disease (ESRD) patients; 2.
- Trial name
- NCT00931970
- Where
- 33 sites in South Korea
- Volunteers
- 5,400 people
- Sponsor
- Clinical Research Center for End Stage Renal Disease, Korea
Renal Failure, Obesity
Use of the INAMED LAPBAND System to Reduce BMI's in Obese Renal Failure Patients
The purpose of this study is to assess the use of this Lap-Band system for the purpose of promoting weight loss in renal failure patients who do not qualify as transplant candidates because of excessive BMI's
- Trial name
- NCT00466882
- Testing
- Inamed Lap-Band System
- Where
- United States
- Sponsor
- Summa Health System
End Stage Renal Disease (ESRD)
Automated Setting of Individualized Sodium Technology
The ASIST study is a medical device study testing the safety and efficacy of a new hemodialysis machine software in chronic haemodialysis patients.
- Trial name
- ASIST (NCT02795286)
- Testing
- Artis Haemodialysis Machine w/ ASIST Software - Isonatremic, Artis Haemodialysis Machine w/ ASIST Software - Isotonic, Artis Haemodialysis Machine w/o ASIST Software
- Where
- Sweden
- Volunteers
- 18 people
- Sponsor
- Vantive Health LLC
Kidney Failure, Chronic
Oral Anticoagulation in Haemodialysis Patients
Guidelines recommend oral anticoagulation with vitamin K antagonists for atrial fibrillation whenever the CHADS2VASC score is superior or equal to 2.
- Trial name
- AVKDIAL (NCT02886962)
- Testing
- No oral anticoagulation, Oral anticoagulation with vitamin K antagonists
- Where
- 25 sites in France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Strasbourg, France
Hemodialysis Complication
Impact of Residual Renal Function on Complications in Chronic Hemodialysis Patients
Our aim is to study the impact of residual renal function on hemodialysis patients mortality and morbidity .
- Trial name
- NCT03854513
- Testing
- dialysis machine
- Volunteers
- 100 people
- Sponsor
- Assiut University
Protein-Energy Malnutrition, Kidney Failure, Chronic
Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients
Malnutrition is seen frequently in hemodialysis units in most developing countries. Malnutrition increases morbidity and mortality in this population and its treatment improves patient survival and health status The purpose of…
- Conditions
- Protein-Energy Malnutrition, Kidney Failure, Chronic, Hemodialysis
- Trial name
- NCT01981083
- Testing
- Egg albumin-based protein supplement, Renal-specific oral supplement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Centro Medico Lic Adolfo Lopez Mate
Chronic Kidney Failure
Phase III Study to Investigate the Safety and Efficacy of Fermagate and Sevelamer Hydrochloride
Magnesium iron hydroxycarbonate is a phosphate binder that absorbs phosphate from food, reducing the amount that the body can absorb.
- Trial name
- NCT00844662
- Testing
- Fermagate, Sevelamer hydrochloride
- Where
- 109 sites in United States, Belgium and 13 more
- Volunteers
- 1,000 people
- Sponsor
- Ineos Healthcare Limited
End-Stage Renal Disease
Aspirin in the Prevention of Cardiovascular Events in Hemodialysis Patients
The study is prospectively initiated to: (1) evaluate the alterations in platelet function to aspirin therapy and the prevalence of aspirin resistance in patients with chronic kidney disease undergoing hemodialysis, and (2)…
- Trial name
- NCT01198379
- Testing
- aspirin
- Where
- Taiwan
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.