Clinical trials: Complication of Hemodialysis
ESRD
Impact Of Mindfulness Meditation On Pain, Quality Of Sleep, Self-Esteem
Background: Hemodialysis affects patients' lives and is associated with social, occupational, psychological, and societal problems.
- Trial name
- NCT06064994
- Testing
- Mindfulness meditation
- Where
- Jordan
- Volunteers
- 60 people
- Sponsor
- Jordan University of Science and Technology
Hemodialysis Complication, Bleeding
Regional Anticoagulation of Dialysis Circuits With a Calcium-free Citrate-containing Dialysate
Critically ill patients have a high risk of bleeding but also require prolonged intermittent dialysis. Thus, a heparin-free easy-to-use alternative type of anticoagulation within the dialysis circuit is required.
- Trial name
- C2D (NCT03842657)
- Testing
- anticoagulation of the dialysis circuit
- Where
- 5 sites in France
- Volunteers
- 97 people
- Sponsor
- University Hospital, Toulouse
End-stage Kidney Disease
Vitamin K to Attenuate Coronary Artery Calcification in Hemodialysis Patients
The purpose of this study is to see if vitamin K supplementation three times per week reduces the progression of coronary artery calcification over 12 months in dialysis patients compared to placebo.
- Trial name
- iPACK-HD (NCT01528800)
- Testing
- Vitamin K1, Microcrystalline Methylcellulose
- Where
- 3 sites in Canada
- Volunteers
- 85 people
- Sponsor
- Dr. Rachel Holden
End Stage Renal Disease
Pharmacokinetics and Optimal Dose of Ertapenem in Hemodialysis Patients
The purpose of this study is to determine the amount of ertapenem in the blood over time between hemodialysis session.
- Trial name
- NCT02159859
- Testing
- Ertapenem
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Corewell Health East
Chronic Kidney Diseases, Peritoneal Dialysis
Effects of Curcumin Supplementation in Patients With Chronic Kidney Disease on Peritoneal Dialysis
The objective of this study is to assess whether supplementation with curcumin could modulate the intestinal microbiota, reducing levels of inflammatory markers of oxidative stress, uremic toxins and inflammasome, in patients…
- Conditions
- Chronic Kidney Diseases, Peritoneal Dialysis, Hemodialysis
- Trial name
- NCT04413266
- Testing
- Curcumin supplementation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Protein-Energy Malnutrition, Kidney Failure, Chronic
Egg Albumin-Based Protein Supplement Versus Renal-specific Supplement in Hemodialysis Patients
Malnutrition is seen frequently in hemodialysis units in most developing countries. Malnutrition increases morbidity and mortality in this population and its treatment improves patient survival and health status The purpose of…
- Conditions
- Protein-Energy Malnutrition, Kidney Failure, Chronic, Hemodialysis
- Trial name
- NCT01981083
- Testing
- Egg albumin-based protein supplement, Renal-specific oral supplement
- Where
- Mexico
- Volunteers
- 60 people
- Sponsor
- Centro Medico Lic Adolfo Lopez Mate
End-Stage Renal Disease
Study to Compare Safety and Tolerability of AKST1210 Column at 2 Blood Flow Rates in Subjects With ESRD on Hemodialysis
This study is to evaluate the safety and tolerability of the AKST1210 column at blood-flow rates greater than 250 mL/min in subjects with end-stage renal disease (ESRD) undergoing hemodialysis (HD).
- Trial name
- NCT04985383
- Testing
- AKST1210 S-15 at 250 mL/min, AKST1210 S-15 at 450 mL/min, AKST1210 S-25 at 250 mL/min
- Where
- 4 sites in United States
- Volunteers
- 10 people
- Sponsor
- Alkahest, Inc.
End Stage Renal Disease
Health Effects of oraL Protein Supplements in HD (The HELPS-HD Trial)
To conduct a pragmatic randomized clinical trial in which the researchers will determine the mortality impact of a protocol whereby all hemodialysis patients receive an oral, protein-based nutritional supplement during the…
- Trial name
- HELPS-HD (NCT02933151)
- Testing
- Nutritional Supplement
- Where
- 2 sites in United States
- Volunteers
- 10,457 people
- Sponsor
- Dialysis Clinic, Inc.
Chronic Hepatitis C Virus
Study of Ombitasvir/Paritaprevir/Ritonavir in Japanese Adults With Genotype 1b Chronic Hepatitis C Virus (HCV) Infection With End Stage Renal Disease (ESRD) on Hemodialysis (HD)
The purpose of this multicenter, single-arm, combination-drug study, which includes 12 weeks of treatment and 24 weeks of follow-up, is to evaluate the safety, efficacy and pharmacokinetics of ombitasvir/paritaprevir/ritonavir in…
- Trial name
- GIFT-R (NCT02806362)
- Testing
- Ombitasvir/paritaprevir/ritonavir
- Sponsor
- AbbVie
Depression, Hemodialysis Complication
Depression Inventory for Maintenance Hemodialysis Patients
Depression is frequently seen among hemodialysis patients; however, it causes an impaired quality of life, a decrease in adherence to treatment, and an increase in hospitalization and mortality rate.
- Conditions
- Depression, Hemodialysis Complication, Management, Risk Behavior
- Trial name
- Depression (NCT06844890)
- Where
- Turkey (Türkiye)
- Volunteers
- 283 people
- Sponsor
- Istanbul University
Vascular Access Complication, Hemodialysis Access Failure
Optimizing Access Surgery In Senior Hemodialysis Patients
The number of elderly hemodialysis patients is growing. Vascular access complications are a major determinant of the quality of life and health care costs for these vulnerable patients.
- Conditions
- Vascular Access Complication, Hemodialysis Access Failure, Dialysis Access Malfunction, Arteriovenous Fistula
- Trial name
- OASIS (NCT05911451)
- Testing
- Arteriovenous fistula creation, Arteriovenous graft placement, Central venous catheter placement
- Where
- 20 sites in Netherlands
- Volunteers
- 166 people
- Sponsor
- Maastricht University Medical Center
Hemodialysis Complication, Dialysis; Complications
Handheld Ultrasound-guided Cannulation of Difficult Haemodialysis Arteriovenous Access by Renal Nurses
Cannulation of complex arteriovenous fistula (AVF) or graft (AVG) is a challenge to renal nurses. Ultrasound (US) guidance on central and peripheral venous access visualisation has been widely adopted in nephrology and shown to…
- Conditions
- Hemodialysis Complication, Dialysis; Complications, Vascular Access Site Haematoma, Vascular Access Complication
- Trial name
- NCT05410691
- Testing
- Handheld US device
- Where
- Singapore
- Volunteers
- 50 people
- Sponsor
- National Healthcare Group, Singapore
Cardiovascular Diseases, Chronic Kidney Diseases
The Impact of Conventional Hemodialysis and Renal Transplantation on the Global Longitudinal Strain of the Left Ventricle
The objective of this study is to evaluate a group of patients with chronic kidney disease in stages 3-5 by conventional 2D echocardiography, tissue Doppler techniques and speckle tracking - LV GLS and determine the correlation…
- Conditions
- Cardiovascular Diseases, Chronic Kidney Diseases, Fibrosis
- Trial name
- NCT05685823
- Where
- Romania
- Volunteers
- 140 people
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Kidney Failure, Renal Insufficiency, Chronic
Effect of Dialysis Membranes on Inflammatory and Immune Processes in Hemodialysis
Double blinded, randomized controlled trial evaluating medium cut-off dialyzer compared to high flux dialyzer in ironic hemodialysis patients over a 6 months period with 3 months crossovers.
- Conditions
- Kidney Failure, Renal Insufficiency, Chronic, Dialysis Related Complication
- Trial name
- NCT03836508
- Testing
- Medium cut-off, High-Flux
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Renal Disease
Vitamin K2 Supplementation and Vascular Calcification
Vascular calcification is the leading cause of death in patients with end stage renal disease (ESRD) in hemodialysis. The protein matrix Gla vitamin K dependent (MGP) is a potent inhibitor of the vascular calcification.
- Trial name
- NCT04539418
- Testing
- Vitamin K 2
- Volunteers
- 59 people
- Sponsor
- Catholic University of Salta
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Dyspnea, Chronic Renal Failure
POCUS VS CT in Diagnosis of Acute Dyspnea in Chronic Hemodialysis Patients
Estimate the predictive value of POCUS in diagnosis of different causes of acute dyspnea in hemodialysis patients and compare between POCUS and CT in differentiation the causes of acute dyspnea in those population.
- Trial name
- NCT05729035
- Testing
- POCUS
- Volunteers
- 100 people
- Sponsor
- Randa Ahmed Sarhan
Peer Review, Hemodialysis Complication
Peer Support Program in Chronic Kidney Patient
The main advantage of patient-to-patient peer counseling is that it benefits both the client and the peer mentors as real and authentic experiences are shared.
- Conditions
- Peer Review, Hemodialysis Complication, Nurse's Role, Health-Related Behavior
- Trial name
- NCT06555718
- Testing
- The Peer Support Program, Standart care
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Acibadem University
End Stage Renal Disease
The Use of Furosemide in Patients on Dialysis
Patients often begin dialysis taking diuretics (stimulate the kidney to excrete salt and water). Once on dialysis, these drugs are often continued.
- Trial name
- NCT01815892
- Testing
- Withdrawal of furosemide, furosemide administration
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Unity Health Toronto
End-Stage Kidney Disease (ESKD)
Virtual Reality-Guided Imagery in Hemodialysis Patients ( VRGI-HD )
This randomized controlled trial aims to evaluate the effect of virtual reality guided imagery on selected health outcomes among adult patients receiving maintenance hemodialysis.
- Trial name
- NCT07867444
- Testing
- virtual reality-guided imagery (VRGI)
- Volunteers
- 80 people
- Sponsor
- Islamic University of Najaf
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