Clinical trials: Complication of Hemodialysis
End Stage Renal Disease (ESRD), Chronic Kidney Disease on Hemodialysis
Expanded Hemodialysis Versus High-Volume Online Hemodiafiltration for Uremic Toxin Removal
People with advanced kidney disease need dialysis to remove waste products from the blood. Some of these waste products, called uremic toxins, are small, while others are medium-sized and more difficult to remove.
- Conditions
- End Stage Renal Disease (ESRD), Chronic Kidney Disease on Hemodialysis, Renal Dialysis, Uremia; Chronic
- Trial name
- REMOV-HDx (NCT07348536)
- Testing
- Expanded Hemodialysis With Medium Cut-Off Membrane, High-Volume Online Hemodiafiltration
- Where
- Mexico
- Volunteers
- 15 people
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
End-Stage Renal Disease, Hemodialysis Complication
Effects of Mindfulness Meditation on Hemodialysis Patients
Objective: This study aimed to examine the effects of mindfulness meditation on the quality of sleep, perceived stress, serum cortisol, and C-reactive protein in end-stage renal disease patients undergoing hemodialysis.
- Trial name
- RCT (NCT06936293)
- Testing
- Mindfulness Meditation
- Where
- Kuwait
- Volunteers
- 56 people
- Sponsor
- University of Jordan
Kidney Failure, Chronic, Anemia
A Study of the Safety and Efficacy of Long-term Correction of Anemia With Epoetin Alfa in Early Hemodialysis Patients
The purpose of this study in early hemodialysis patients (on dialysis 3 to 18 months) is to assess the effect of correction versus partial correction of anemia using epoetin alfa on heart pumping function.
- Trial name
- NCT00261521
- Testing
- epoetin alfa
- Volunteers
- 596 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Malnutrition, ESRD
ProStat Supplementation in Dialysis Patients
This is a long-term, randomized, placebo-controlled, double blind clinical study of a nutritional supplement, ProStat 64, in chronic hemodialysis patients with poor nutrition.
- Trial name
- NCT00435123
- Testing
- Nutritional Supplement ProStat 64 twice a day
- Where
- 6 sites in United States
- Volunteers
- 16 people
- Sponsor
- Fresenius Medical Care North America
Chronic Kidney Disease, End Stage Renal Disease
Open-Label Extension Study for the Long-Term Efficacy and Safety of Roxadustat in Participants With Dialysis and Non-Dialysis Chronic Kidney Disease
The purpose of this open-label extension study is to evaluate long-term efficacy and safety of roxadustat in maintaining hemoglobin (Hb) in participants with dialysis and non-dialysis chronic kidney disease (CKD) who have…
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Anemia
- Trial name
- NCT01630889
- Testing
- Roxadustat
- Where
- 7 sites in United States, Puerto Rico
- Volunteers
- 15 people
- Sponsor
- Kyntra Bio
Renal Failure Chronic, Anxiety
The Effect of Various Music Therapies and Robotic Parrot Therapy on Anxiety and Fatigue Levels
This study aimed to evaluate the effect of robotic parrot therapy, live music, and live ney sound therapy on anxiety and fatigue levels in hemodialysis patients.
- Conditions
- Renal Failure Chronic, Anxiety, Fatigue
- Trial name
- NCT07238374
- Testing
- Music-Repeating Robotic Parrot (Pet therapy), Live Music (Pet therapy), Live Ney Sound (Pet therapy)
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Karadeniz Technical University
Acute Kidney Injury
Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury
This is a multi-center randomized clinical trial study. The purpose of this study is to examine safety, feasibility and efficacy of automated peritoneal dialysis as compared with intermittent hemodialysis for AKI patients with…
- Trial name
- SAFE-APD (NCT03598387)
- Testing
- Automated peritoneal dialysis, Intermittent hemodialysis
- Where
- 5 sites in China
- Volunteers
- 100 people
- Sponsor
- Limeng Chen
End-Stage Kidney Disease, Hemodialysis
Effect of Sodium Rinsing Fluid on Blood Pressure and Interdialytic Weight Change in Hemodialysis Patients
This is a prospective, randomized, double-blind, parallel group trial to assess the efficacy and safety of intravenous dextrose 5% solution compare with normal saline (standard care) in wash back procedure during haemodialysis in…
- Trial name
- NSD5 (NCT02590081)
- Testing
- Dextrose 5%, normal saline
- Where
- 15 sites in Malaysia
- Volunteers
- 434 people
- Sponsor
- Penang Hospital, Malaysia
End Stage Renal Disease on Dialysis (Diagnosis)
Targeted Deprescribing in Patients on Hemodialysis
Hemodialysis (HD) patients take more pills per day on average than any other chronically ill patient population. On average, an HD patient takes 19 medications per day, of which 70% may not be appropriate.
- Trial name
- NCT03733262
- Testing
- De-prescribing Trial
- Where
- 4 sites in Canada
- Volunteers
- 480 people
- Sponsor
- University Health Network, Toronto
Hemodialysis, Healthy
Study to Evaluate the Pharmacokinetics and Metabolism of [14C] CR845 (Difelikefalin) in Patients With End Stage Renal Disease on Hemodialysis and in Healthy Subjects
The objectives of this study are to evaluate the in vivo metabolite profiling and characterization of CR845 administered intravenously (IV) in patients on hemodialysis (HD) and in healthy subjects; and to determine the…
- Trial name
- NCT03947970
- Testing
- [14C] CR845
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Cara Therapeutics, Inc.
Kidney Failure, Chronic
Trial of Aerobic Exercise in Patients Undergoing Outpatient Hemodialysis
Randomized controlled trial comparing effects of ergometer exercise during hemodialysis to effects of pedometer use outside of hemodialysis on exercise capacity, functional status, quality of life and adequacy of hemodialysis.
- Trial name
- NCT00492362
- Testing
- ergometer exercise during hemodialysis, pedometer activity outside of hemodialysis
- Where
- 4 sites in Canada
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
End Stage Kidney Disease
Investigation of Performance and Compatibility of the Baxter Dialyzer Xenium XPH 210 During On-line Hemodiafiltration
The proposed study seeks to determine the appropriate balance between the removal of undesirable small molecular substances (urea, creatinine, phosphate) and large molecular substances (ß2-m) and the retention of important…
- Trial name
- NCT00976846
- Testing
- Dialyzer Baxter Xenium XPH 210
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- Praxisverbund Dialyse und Apherese
Kidney Failure, Chronic
Evaluation of the Integrated Home Dialysis Model
The purpose of this study is to evaluate which home dialysis modality pattern (home hemodialysis [HHD], peritoneal dialysis [PD] or a combination of both, e.g.
- Trial name
- NCT02278159
- Testing
- Peritoneal dialysis, Home hemodialysis
- Volunteers
- 11,600 people
- Sponsor
- Princess Alexandra Hospital, Brisbane, Australia
End-stage Renal Disease, Left Ventricular Hypertrophy
In-Centre Nocturnal Hemodialysis (INHD): A Long-Term Follow-Up Study
Background: In 2010, approximately 39000 Canadians had end-stage renal disease (ESRD), and the prevalence rate of dialysis has increased by 189% over the past 2 decades.
- Trial name
- INHD (NCT02684773)
- Testing
- Conventional Hemodialysis, In-centre Nocturnal Hemodialysis
- Where
- 2 sites in Canada
- Volunteers
- 67 people
- Sponsor
- Unity Health Toronto
Hyperphosphatemia, End Stage Renal Disease
Ferric Citrate for the Treatment of Hyperphosphatemia in Patients With Chronic Kidney Disease Undergoing Hemodialysis
To evaluate the efficacy and safety of ferric citrate capsules for the treatment of hyperphosphatemia in patients with chronic kidney disease undergoing hemodialysis
- Conditions
- Hyperphosphatemia, End Stage Renal Disease, ESRD
- Trial name
- NCT03984760
- Testing
- Ferric Citrate, Sevelamer Carbonate
- Where
- 24 sites in China
- Volunteers
- 240 people
- Sponsor
- Panion & BF Biotech Inc.
Anemia
Evaluation of the Conversion From Peginesatide to Epoetin Alfa in Patients Receiving Hemodialysis
The purpose of this study is to evaluate whether hemodialysis patients on peginesatide can be converted to epoetin alfa by using a predefined conversion table while achieving a stable hemoglobin.
- Trial name
- NCT01737879
- Testing
- Peginesatide, Epoetin alfa
- Where
- 23 sites in United States
- Volunteers
- 41 people
- Sponsor
- Amgen
End Stage Renal Disease, Chronic Hemolysis
Development of an Innovative Hemodialysis Method to Improve Dialytic Clearance of Protein-bound Uremic Toxins
Current hemodialysis techniques fail to efficiently remove protein-bound uremic toxins (such as p-cresyl sulfate (p-CS) or indoxyl sulfate (IS)) due to their strong binding to serum albumin.
- Trial name
- CLEARTOX (NCT06595680)
- Testing
- Medialipide 20% perfusion, NaCl 0,9%, Blood sample
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hospices Civils de Lyon
Nursing Caries, Hemodialysis Complication
Muscle Cramps in Hemodialysis Patients: A Randomized Controlled Trial
Muscle cramps are a common and distressing issue among hemodialysis patients, significantly impacting their quality of life. Non-pharmacological approaches are increasingly being explored to alleviate these symptoms.
- Conditions
- Nursing Caries, Hemodialysis Complication, Exercise Addiction
- Trial name
- NCT06866470
- Testing
- relaxation group, massage
- Where
- Turkey (Türkiye)
- Volunteers
- 79 people
- Sponsor
- University of Yalova
Hemodialysis Complication
Music Therapy for Individuals Receiving Hemodialysis Treatment
There are studies in the world where music therapy is used in the management of symptoms in hemodialysis, but the number of studies in our country is insufficient.
- Trial name
- NCT06207669
- Testing
- Music therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Amasya University
Chronic Kidney Diseases
Intradialisis Physical Exercise in Quality of Life and Health
Evaluate the effectiveness of different modalities of physical exercise about clinical health indicators and quality of life of patients with chronic kidney disease undergoing hemodialysis.
- Trial name
- EJERINTRA (NCT05207527)
- Testing
- cardiovascular exercise, Muscle strength, Mixed
- Volunteers
- 120 people
- Sponsor
- Universidad del Rosario
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.