Clinical trials: Complication of Infusion
Sedation Complication
Comparison Between Sevoflurane and Propofol for Maintenance of Sedation During ERCP
After approval of ethical committee of Sindh Institute of Urology \& Transplantation (SIUT), 86 patients were enrolled for the elective endoscopic retrograde cholangiopancreatography (ERCP).
- Trial name
- NCT05996588
- Testing
- Propofol 1 % Injectable Suspension, Sevoflurane
- Where
- Pakistan
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sindh Institute of Urology and Transplantation
Postoperative Pain, Postoperative Nausea and Vomiting
A Study to Assess Analgesic Efficacy of Intravenous Lignocaine
The primary objectives of this study are to analyse the effect of perioperative systemic infusion of lignocaine on postoperative pain, postoperative nausea and vomiting and perioperative levels of inflammatory mediators in…
- Conditions
- Postoperative Pain, Postoperative Nausea and Vomiting, Postoperative Ileus
- Trial name
- NCT01699919
- Testing
- Intravenous lignocaine
- Where
- India
- Volunteers
- 134 people
- Sponsor
- Jawaharlal Institute of Postgraduate Medical Education & Research
Encephalopathy, Developmental Delay and Behavioral Changes
RCT for Intermittent Versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
RCT for Intermittent versus Continuous Propofol Sedation for Pediatric Brain and Spine MRI Studies
- Conditions
- Encephalopathy, Developmental Delay and Behavioral Changes, Cord Tumor Compression or Instability, Cord Tethering or Malformation
- Trial name
- NCT00515359
- Testing
- Intermittent Propofol Sedation, Continuous Propofol Sedation
- Where
- United States
- Volunteers
- 276 people
- Sponsor
- Corewell Health West
Coronary Artery Bypass Surgery, Coronary Heart Disease
Clinical Study to Evaluate Nesiritide in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery A014 / NAPA
The purpose of this study is to assess the effects of nesiritide compared to placebo when given with standard of care therapies, on kidney function, heart function and the need of other treatments in heart failure patients…
- Conditions
- Coronary Artery Bypass Surgery, Coronary Heart Disease, Coronary Artery Bypass Grafting, Cardiopulmonary Bypass
- Trial name
- NCT00653042
- Testing
- Nesiritide
- Volunteers
- 305 people
- Sponsor
- Scios, Inc.
Graft-Versus-Host Disease
Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications
Background: Bone marrow stromal cells (BMSC) from bone marrow biopsies can be used to treat disorders that cause inflammation and immune system diseases.
- Trial name
- NCT01633229
- Testing
- Bone Marrow Stromal Cell Infusion
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Post-mastectomy Pain Syndrome, Breast Cancer
Prevention of Persistent Pain With LidocAine iNfusions in Breast Cancer Surgery (PLAN)
Phase III, international multicentre, parallel group, blinded, 1:1 randomized controlled trial to determine the effect of an intraoperative intravenous lidocaine infusion on reducing the development of persistent pain 3-months…
- Conditions
- Post-mastectomy Pain Syndrome, Breast Cancer, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04874038
- Testing
- Lidocaine 20mg/ml
- Where
- 17 sites in Canada, Nepal and 1 more
- Volunteers
- 1,604 people
- Sponsor
- University Health Network, Toronto
Critical Illness, Pediatrics
Effect of Giving Reduced Fluid in Children After Trauma
This study is designed to help decide how much intravenous (IV) fluid should be given to pediatric trauma patients. No standard currently exists for managing fluids in critically ill pediatric trauma patients, and many fluid…
- Conditions
- Critical Illness, Pediatrics, General Surgery, Fluid Therapy
- Trial name
- NCT04201704
- Testing
- Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume
- Where
- 4 sites in United States
- Volunteers
- 250 people
- Sponsor
- Columbia University
Neoplasm Malignant, Breast Cancer
Shorter Scalp Cooling Time in Paclitaxel
Chemotherapy-induced alopecia (CIA) is one of the most distressing side effects for patients. Scalp cooling can prevent or minimise CIA in approximately half of all patients, depending on many factors, e.g.
- Conditions
- Neoplasm Malignant, Breast Cancer, Ovarian Cancer
- Trial name
- COP (NCT03266185)
- Testing
- Shorter PICT
- Where
- Netherlands
- Volunteers
- 91 people
- Sponsor
- Leiden University Medical Center
Scheduled Cardiac Surgery, Sternotomy
Postoperative Rehabilitation After Cardiac Surgery in Patients at Risk of Respiratory Complications. Effects of a Continuous Bi-laterosternal Infusion of Ropivacaine Through Multihole Catheters
Postoperative pain after cardiac surgery is a risk factor for postoperative complications. In cardiac surgery, pain is more intense during the first 48 hours and disturbs the patient's capacity of coughing, deep breathing, and…
- Conditions
- Scheduled Cardiac Surgery, Sternotomy, Elderly Patients, Obesity
- Trial name
- BLS-Sterno (NCT01828788)
- Testing
- Ropivacaine
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
End-stage Renal Disease
Sodium Chloride and Protein-Bound Toxin Removal in Hemodiafiltration
An increase of the free fraction may allow a better removal of of protein-bound uremic toxins during dialysis. During predilution hemodiafiltration, the sodium chloride (NaCl) concentration will be increased in the infusion fluid…
- Trial name
- NCT01923961
- Testing
- HDF NaCl, Hemodialysis, Standard Predilution Hemodiafiltration
- Where
- Germany
- Volunteers
- 8 people
- Sponsor
- EXcorLab GmbH
Cancer
Donor Mesenchymal Stem Cell Infusion in Treating Patients With Acute or Chronic Graft-Versus-Host Disease After Undergoing a Donor Stem Cell Transplant
RATIONALE: Donor mesenchymal stem cell infusion may be an effective treatment for acute or chronic graft-versus-host disease caused by a donor stem cell transplant.
- Trial name
- NCT00361049
- Testing
- graft versus host disease prophylaxis/therapy, fluorescence in situ hybridization, immunoenzyme technique
- Where
- 8 sites in United States
- Volunteers
- 49 people
- Sponsor
- Case Comprehensive Cancer Center
Pain, Postoperative
Ketorolac Applied by Continuous IV Infusion for Treatment of Moderately Severe Postoperative Pain Following Bunionectomy
This clinical study is a randomized, double-blind, double-dummy, parallel group, multi-center, active and placebo-controlled trial evaluating the analgesic efficacy and safety of NTM-001 in subjects with moderately severe…
- Trial name
- NCT05324358
- Testing
- Ketorolac Tromethamine, Morphine Sulfate
- Where
- 10 sites in United States
- Volunteers
- 341 people
- Sponsor
- Neumentum, Inc.
Bladder Carcinoma, Post-operative Pain
Continuous Infusion of Ropivacaine Hydrochloride in Reducing Pain After Surgery in Patients With Bladder Cancer
This randomized phase IV trial studies how well the continuous infusion of ropivacaine hydrochloride works in reducing pain after surgery in patients with bladder cancer.
- Trial name
- NCT02438852
- Testing
- Questionnaire Administration, Ropivacaine Hydrochloride
- Where
- United States
- Sponsor
- University of Southern California
Adverse Effect, Anesthesia
Airway Management During TCI vs RSI Anesthesia Induction
The aims of this observational study is to evaluate and compare feasibility of airway management during standardized TCI and RSI anesthesia induction.
- Conditions
- Adverse Effect, Anesthesia, Airway Complication of Anesthesia
- Trial name
- NCT03723109
- Testing
- Induction of anesthesia
- Where
- Sweden
- Volunteers
- 70 people
- Sponsor
- Umeå University
Hyperalgesia
Opioid-induced Hyperalgesia After Remifentanil Infusion
Remifentanil is a rapid-acting opioid which has been widely used in pain treatment during surgery for the last 15 years 1. Remifentanil is rapidly eliminated (minutes) from the body after end of infusion, and this makes it easily…
- Trial name
- NCT01702389
- Testing
- Remifentanil
- Where
- Norway
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Oslo University Hospital
Ovarian Cancer, Fallopian Tube Cancer
Standard Infusion Carboplatin Versus Prophylactic Extended Infusion Carboplatin in Patients With Patients With Recurrent, Ovary, Fallopian Tube, and Primary Peritoneal Cancer
Patients who have this kind of cancer are often treated with several drugs. Carboplatin is one that seems to work for many treatment cycles. Even though it may work against the cancer, the patient can become allergic to it.
- Conditions
- Ovarian Cancer, Fallopian Tube Cancer, Peritoneal Cancer
- Trial name
- NCT01248962
- Testing
- carboplatin
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Bladder Tumors, Spinal Anesthesia
Magnesium vs. Dexmedetomidine in TURBT Under Spinal Anesthesia
This randomized controlled trial evaluated the effects of intraoperative intravenous magnesium sulfate versus dexmedetomidine on postoperative pain, analgesic consumption, hemodynamic stability, and respiratory function in…
- Conditions
- Bladder Tumors, Spinal Anesthesia, Postoperative Pain, Magnesium Sulfate
- Trial name
- TURBT (NCT07445451)
- Testing
- magnesium sulfate, Dexmedetomidine, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 93 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement
Effects of Bolus Versus Infusion Ketamine During Laparoscopic Cholecystectomy
This prospective, randomized, controlled study evaluated the effects of different ketamine administration strategies in adult patients undergoing elective laparoscopic cholecystectomy under general anesthesia.
- Conditions
- Laparoscopic Cholecystectomy, Optic Nerve Sheath Diameter Measurement, Ketamine, Postoperative Pain
- Trial name
- ketamine (NCT07900854)
- Testing
- ketamine bolus, ketamin infusion, Normal Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Kartal Kosuyolu Yuksek Ihtisas Education and Research Hospital
Post-operative Pain
Patient Re-education vs. Background Morphine to IV-PCA in Patient With Unsatisfactory Analgesia Post Laparotomy
The purpose of this study is to improve IV-Patient Controlled Analgesia (IV-PCA) technique for postoperative analgesia. Investigators are comparing between patient re-education and the background morphine infusion among patients…
- Trial name
- NCT02523846
- Testing
- morphine, Patient re-education
- Where
- Malaysia
- Volunteers
- 160 people
- Sponsor
- Clinical Research Centre, Malaysia
Regional Anesthesia Morbidity, Pain, Postoperative
Efficacy of Ultrasound Guided ESP Vs Video-assisted PVB Catheter Placement in Minimally Invasive Thoracic Surgery
Minimally Invasive Thoracic Surgery (MITS) is a surgical method used to perform lung surgery through small incisions between the ribs and includes both Video-Assisted Thoracic Surgery (VATS) and Robotic assisted Thoracic Surgery…
- Conditions
- Regional Anesthesia Morbidity, Pain, Postoperative, Pain, Chronic
- Trial name
- NCT04729712
- Testing
- Anaesthesiologist-administered ultrasound guided Erector Spinae block with catheter insertion, Surgeon-administered video-assisted Paravertebral block with catheter insertion
- Where
- 2 sites in Ireland
- Volunteers
- 80 people
- Sponsor
- Mater Misericordiae University Hospital