Clinical trials: Complication of Infusion
Congestive Heart Failure, Heart Failure
AB-1002 in Patients With Class III Heart Failure
This is a Phase 1, prospective, multi-center, open-label, sequential dose escalation study to explore the safety, feasibility, and efficacy of a single intracoronary infusion of AB-1002 in patients with NYHA Class III heart…
- Conditions
- Congestive Heart Failure, Heart Failure, Heart Disease, Ischemic, Cardiovascular Diseases
- Trial name
- NAN-CS101 (NCT04179643)
- Testing
- 3 x 10e13vg AB-1002
- Where
- 4 sites in United States
- Volunteers
- 11 people
- Sponsor
- AskBio Inc
Coronary Artery Disease, Blood Transfusion Complication
Re-infusion of Unwashed Shed Blood During Off-pump Surgery
To assess the efficacy and side-effects of re-infusion of unwashed shed blood during off-pump coronary artery surgery using a novel cardiotomy circuit.
- Conditions
- Coronary Artery Disease, Blood Transfusion Complication, Cardiovascular Complication
- Trial name
- NCT06358079
- Testing
- Re-infusion of unwashed shed blood
- Where
- Syria
- Volunteers
- 50 people
- Sponsor
- Damascus University
Postoperative Pain
Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative Pain
Background: The use of low-dose continuous infusion of S(+)-ketamine combined with target-controlled intravenous anesthesia with remifentanil and propofol may be related to the control of postoperative pain and of opioid-induced…
- Trial name
- NCT02421913
- Testing
- S(+)-Ketamine
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Centro Medico Campinas
Pediatric Continuous Renal Replacement Therapy, Dialysis
Safety and TDM of Continuous Infusion Vancomycin Through Continuous Renal Replacement Therapy Solution
The purpose of this investigation is to evaluate the safety of delivering continuous infusion (CI) vancomycin in pediatric CRRT by utilizing CI via by mixing the vancomycin into the CRRT solution(s).
- Conditions
- Pediatric Continuous Renal Replacement Therapy, Dialysis, Renal Failure
- Trial name
- NCT02663596
- Testing
- Vancomycin
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Drexel University
Ovarian Cancer, Primary Peritoneal Cavity Cancer
Paclitaxel and Cisplatin in Treating Patients With Stage III or Stage IV Ovarian Cancer or Primary Peritoneal Cancer
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.
- Trial name
- NCT00002717
- Testing
- cisplatin, paclitaxel
- Where
- 52 sites in United States
- Volunteers
- 324 people
- Sponsor
- Gynecologic Oncology Group
Hemodynamic Instability, Intubation Complication
Effect-site Concentration of Remifentanil for Double-lumen Tubes Intubation: Airtraq VS Macintosh Laryngoscope
The 50% effective concentration of remifentanil by target controlled infusion was not determined for inhibiting the haemodynamic response during double-lumen tube (DLT) intubation.
- Trial name
- NCT03653910
- Testing
- Airtraq, Macintosh
- Where
- China
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Huazhong University of Science and Technology
Gender Difference in V2 Receptor Function in Response to dDAVP Infusion, Nocturia
The Effect of Gender on Antidiuresis - Evaluated by Graded Low Dose Desmopressin Infusion
There is substantial evidence that women throughout life have significantly lower plasma levels of the antidiuretic hormone vasopressin (pAVP) compared to men.
- Conditions
- Gender Difference in V2 Receptor Function in Response to dDAVP Infusion, Nocturia, Nocturnal Enuresis
- Trial name
- NCT02068560
- Testing
- dDAVP infusion
- Where
- Denmark
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stoma Ileostomy, Ileostomy; Complications
Pilot Study of Preoperative Intestinal Training Using Antegrade Ileostomy Infusion
This research study is being conducted to study the effect of infusing your contents from your ostomy bag back into your intestine to re-train them prior to the ostomy takedown operation, which is a surgery to reverse your ostomy…
- Trial name
- NCT06461559
- Testing
- antegrade infusion of ileostomy content
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of California, San Diego
Uterine Myoma, Persistent Post-menpausal Bleeding
Intravenous or Intra-abdominal Local Anesthetics for Postoperative Pain Management.
Local anesthetics (LA) are increasingly used for postoperative pain management. Speicifically, several studies have found benefit of LA injected intra-abdominally following abdominal hysterectomy.
- Conditions
- Uterine Myoma, Persistent Post-menpausal Bleeding, Uterine Cancer
- Trial name
- PoPuLAR (NCT01492179)
- Testing
- Normal saline, Intravenous Lidocaine, Intra-abdominal Lidocaine
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Örebro University, Sweden
Postoperative Pain
A Comparison of Bupivacaine and Ketorolac for Postoperative Analgesia After Iliac Crest Bone Harvesting
The efficacy of three postoperative pain management regimens will be compared in patients undergoing Lefort I osteotomy or alveolar cleft repair with Iliac crest bone grafts (ICBG) to determine the best way of managing…
- Trial name
- NCT00405262
- Testing
- Ketorolac, Bupivacaine, ketorolac + bupivacaine
- Where
- Canada
- Volunteers
- 54 people
- Sponsor
- The Hospital for Sick Children
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Graft-Versus-Host Disease
Bone Marrow Stromal Cell Infusions for Stem Cell Transplant Complications
Background: Bone marrow stromal cells (BMSC) from bone marrow biopsies can be used to treat disorders that cause inflammation and immune system diseases.
- Trial name
- NCT01633229
- Testing
- Bone Marrow Stromal Cell Infusion
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Polycystic Kidney, Autosomal Dominant
The Effect of High and Low Sodium Intake on Urinary Aquaporin-2 in Autosomal Dominant Polycystic Kidney Disease
The aim of the study is to test the following hypotheses: 1. that the function and/or regulation of AQP2 and /or ENaC in the principal cells is abnormal in autosomal dominant polycystic kidney disease. 2.
- Trial name
- NCT00410007
- Testing
- High Sodium Diet, Low Sodium Diet, Hypertonic saline infusion
- Where
- Denmark
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Carolina Cannillo
Head and Neck Cancer, Lung Cancer
Liposomal Lurtotecan Plus Cisplatin in Treating Patients With Advanced or Metastatic Solid Tumors
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one chemotherapy drug may kill more tumor cells.
- Conditions
- Head and Neck Cancer, Lung Cancer, Ovarian Cancer, Unspecified Adult Solid Tumor, Protocol Specific
- Trial name
- NCT00006036
- Testing
- cisplatin, lurtotecan liposome
- Where
- 3 sites in Canada
- Volunteers
- 14 people
- Sponsor
- NCIC Clinical Trials Group