Clinical trials: Complication of Injection
Dysfunctional Uterine Bleeding
DMPA & High Dose Oral Progestin (MPA) Tablets in Outpatient Treatment of Acute Excessive Vaginal Bleeding
The purpose of this study is to investigate the effectiveness and acceptability of high dose MPA (20mg oral 3 times a day) for 3 days combined with an injection of DMPA 150 mg intramuscularly in the treatment of acute heavy…
- Trial name
- NCT01148420
- Testing
- Medroxyprogesterone 17-Acetate, medroxyprogesterone acetate
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Women's Health Care Clinic, Torrance, California
IVDA
Patterns and Outcomes of Peripheral Vascular Complications Following Self-injection of Addictive Drugs.
Intravascular drug abuse is a common health problem with increasing prevalence throughout the world. The estimated number of IV drug abusers around the world is15.6 millions.
- Trial name
- NCT06579638
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Postpartum Hemorrhage
Oxytocin Via Intramuscular Injection and Intravenous Bolus or Infusion for Prevention of Postpartum Hemorrhage
The study will evaluate whether prophylactic oxytocin administered in the third stage of labor via intravenous (IV) infusion or IV bolus reduces the rate of postpartum hemorrhage compared to intramuscular (IM) injection.
- Trial name
- NCT01914419
- Testing
- Oxytocin
- Where
- 2 sites in Egypt
- Volunteers
- 4,983 people, healthy volunteers welcome
- Sponsor
- Gynuity Health Projects
Renal Insufficiency
PK Study of ACHN-490 Injection in Renally Impaired Subjects
The purposes of this study is to assess the relationship between renal function and pharmacokinetics of ACHN-490 Injection.
- Trial name
- NCT01462136
- Testing
- ACHN-490 Injection
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Achaogen, Inc.
Premature Ovarian Failure
Ovarian Injection of PRP (Platelet -Rich Plasma) Vs Normal Saline in Premature Ovarian Insufficiency
60 cases with premature ovarian insufficiency will be randomized to either receive PRP or saline injection in their ovaries. Then follow up by hormonal \& ultrasound \& clinically to monitor any changes
- Trial name
- NCT04922398
- Testing
- platelet rich plasma, Normal saline
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ahmed Saad
Incidence and Types of Systemic Reactions Occurring After Spinal Steroid Injection in a Large Population
Incidence of Various Types of Systemic Reactions Related to Spinal Steroid Injection: A Prospective Study
Many systemic reactions occur commonly after spinal steroid injections, especially in patients, and may be associated with underlying disease, such as hypertension and diabetes mellitus, as well as steroid dose and repetition of…
- Trial name
- NCT01756196
- Testing
- Spinal Steroid Injection
- Where
- South Korea
- Volunteers
- 997 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Exposure to Toxins from Smoking, Female Infertility
Presence of Toxins from Smoking in the Follicular Fluid of Women Undergoing Intracytoplasmic Sperm Injection Treatment
Smoking is associated with many adverse health effects like circulatory disorders, pulmonary diseases or heart diseases. It was also shown that smoking correlates with a significantly higher risk for miscarriage, preterm birth or…
- Trial name
- NCT03414567
- Where
- Germany
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Infertility Treatment Center Dortmund
Renal Impairments, IgA Nephropathy (IgAN)
A Study of RG002C0106 Injection in Adult Participants With Normal Renal Function and Mild-to-Moderate Renal Impairment
This is a Phase I trial designed to evaluate the impact of renal impairment on the efficacy and safety of the drug by comparing pharmacokinetic (PK) parameters and pharmacodynamic (PD) markers after a single subcutaneous…
- Trial name
- NCT07445906
- Testing
- RG002C0106
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Rigerna Therapeutics Co., Ltd.; Rigerna Therapeutics (Beijing) Co., Ltd.
Postoperative Pain
Evaluation of Effectivity of Erector Spina Plane Block With Different Levels
In last years, erector spinae plane block is widely used in abdominal and thoracic surgeries. Laparoscopic cholecystectomy is one of the most commonly performed surgical operations.
- Trial name
- NCT04316416
- Testing
- T7 Level Erector Spinae Plane Block, T9 Level Erector Spinae Plane Block, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Overactive Bladder
Standard Injections Versus Reduced Injections for Intravesical onabotulinumtoxinA Treatment of Overactive Bladder
OnabotulinumtoxinA is an effective treatment for both idiopathic and neurogenic overactive bladder and was FDA approved for this indication in 2013.
- Trial name
- NCT04020510
- Testing
- onaBoNT-A
- Where
- United States
- Volunteers
- 184 people, healthy volunteers welcome
- Sponsor
- Walter Reed National Military Medical Center
Arthritis Knee, Pain
The Efficiency of Periarticular Multimodal Drug Injection in Pain Management Following Primary Unilateral TKA
This interventional study aims to compare the effectiveness of local multimodal drug periarticular injection in TKA patients with the standard pain control regime that includes opioids, NSAIDs, and other analgesics.
- Conditions
- Arthritis Knee, Pain, Arthroplasty Complications
- Trial name
- NCT06112548
- Testing
- primary unilateral TKA, Bupivacain, ketorolac
- Where
- Syria
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Damascus University
Symptomatic Irreversible Pulpitis (SIP), Dental Pain
Local Dexamethasone Administration in Symptomatic Irreversible Pulpitis
Symptomatic irreversible pulpitis is associated with a high incidence of inadequate pulpal anesthesia during endodontic treatment, particularly in mandibular molar teeth.
- Trial name
- SIPDEX (NCT07672873)
- Testing
- Saline (0.9%, sterile, for infusion), Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Marmara University
Infertility, Female
Study on the Safety and Pharmacokinetics of LM001 and Gonal-F® in Healthy Women
Brief Summary: LM001 is a recombinant human Follicle Stimulating Hormone (r-hFSH) Injection, which is proposed for Assisted Reproductive Technology (ART).
- Trial name
- NCT03535103
- Testing
- Gonal-F®, LM001
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Alphamab Jilin Co., Ltd.
Chronic Renal Impairment
Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 in Patients With Impairment Renal Functions
A Clinical Study Comparatively Evaluating the Pharmacokinetics, Pharmacodynamics and Safety of Intravenous Administration of HSK3486 Injectable Emulsion in Patients with Chronic Renal Impairment and Subjects with Normal Renal…
- Trial name
- NCT04142970
- Testing
- HSK3486
- Where
- China
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Sichuan Haisco Pharmaceutical Group Co., Ltd
IgA Nephropathy
A Study to Evaluate the Safety, Tolerability and Pharmacokinetics Pharmacodynamics of SHR-2010 by Intravenously/Subcutaneously in Healthy Subject
The study is being conducted to Evaluate the Safety, Tolerability and Pharmacokinetics pharmacodynamics of SHR-2010 by intravenously/subcutaneously in Healthy Subject.
- Trial name
- NCT05398510
- Testing
- SHR-2010 injection
- Where
- China
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Guangdong Hengrui Pharmaceutical Co., Ltd