Clinical trials: Complication of Peritoneal Dialysis
Chronic Kidney Diseases, End Stage Renal Disease
Inactivity and Quality of Life in Dialysis Patients
The goal of this observational study is to compare hemodialysis and peritoneal dialysis patients. The main questions it mains to answer are: What is the level of physical activity in hemodialysis and peritoneal dialysis patients?…
- Conditions
- Chronic Kidney Diseases, End Stage Renal Disease, Hemodialysis Complication, Peritoneal Dialysis
- Trial name
- NCT05743998
- Where
- Iran
- Volunteers
- 120 people
- Sponsor
- Pardis Specialized Wellness Institute
Chronic Kidney Disease, Bacterial Infection
Study of the Pharmacokinetics of Daptomycin in Children With Renal Disease
The purpose of this study is to: 1. Study the pharmacokinetics and safety of daptomycin in children on hemodialysis (HD) and peritoneal dialysis (PD). 2. Determine urine, HD and PD clearance of daptomycin.
- Trial name
- NCT01012089
- Testing
- Daptomycin
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of Oklahoma
End-stage Renal Disease
Comparative Study of Prognosis and QOL Between APD-RPM and CAPD
This is an observational, multicenter, parallel control study, planning to enroll 750 eligible patients to receive automated peritoneal dialysis with remote patient management (APD-RPM) and continuous ambulatory peritoneal…
- Trial name
- NCT05738525
- Testing
- APD-RPM
- Where
- China
- Volunteers
- 750 people
- Sponsor
- Chinese PLA General Hospital
Chronic Kidney Disease, End Stage Renal Disease
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden.
- Conditions
- Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
- Trial name
- TEACH-VET (NCT04064086)
- Testing
- Comprehensive Pre-ESRD Patient Education (CPE), Provision of the freely available resources for Kidney Disease Education
- Where
- United States
- Volunteers
- 656 people
- Sponsor
- VA Office of Research and Development
Chronic Kidney Disease
Skin Autofluorescence as a Risk Marker in People Receiving Dialysis.
The purpose of the present study is to investigate the association between the accumulation of advanced glycation end-products (AGE) and adverse outcomes (e.g.
- Trial name
- AGED (NCT02878317)
- Where
- United Kingdom
- Volunteers
- 81 people
- Sponsor
- University of Nottingham
Chronic Kidney Disease, Peritoneal Dialysis
Efficacy and Safety of a 7.5% Icodextrin Peritoneal Dialysis Solution in Once-Daily Long Dwell Exchange
The purpose of this study is to evaluate the efficacy and safety of a 7.5% Icodextrin peritoneal dialysis solution for once-daily long dwell exchange in patients undergoing Continuous Ambulatory Peritoneal Dialysis (CAPD) in…
- Trial name
- NCT00725517
- Testing
- Icodextrin
- Volunteers
- 2 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Fluid Overload Pulmonary Edema, Peritoneal Dialysis Complication
Assessing Fluid Status of Peritoneal Dialysis Patients With Assistance of Lung Ultrasound
As studied previously, lung congestion is very prevalent however usually asymptomatic in dialysis patients. Fluid overload is associated with hospitalizations, worse cardiovascular outcomes and mortality in PD patients.
- Trial name
- Fluid-PLUS (NCT04176627)
- Testing
- Lung ultrasound
- Where
- 16 sites in United States
- Volunteers
- 44 people
- Sponsor
- Satellite Healthcare
Heart Failure, Cardio-Renal Syndrome
A Clinical Study of the Safety and Efficacy of a Wearable Device (CLS UF) That Delivers Continuous Administration of Glucose to Recirculated Peritoneal Dialysis Fluid for the Purpose of Ultrafiltration in Patients With Congestive Heart Failure
A single-center, prospective, non-randomized, clinical and first-in-human study. Each patient will be studied during a single treatment session of ten hours.
- Trial name
- NCT02772146
- Testing
- CLS UF
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Triomed AB
ESRD, CKD (Chronic Kidney Disease) Stage 5D
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
This is a phase II, proof-of-concept, placebo-controlled, double-blind, cross-over randomized clinical trial, assessing the effect of canagliflozin on peritoneal membrane function in patients on PD.
- Trial name
- CAN-PD (NCT06913647)
- Testing
- Canagliflozin 300 MG
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
ESRD, Peritoneal Dialysis
Effect of N-Acetylcysteine on Peritoneal Membrane Function in Chronic Peritoneal Dialysis Patients
The aim of our study is to investigate the effect of N-acetylcysteine on peritoneal small solute clearance and removal of salt and water in prevalent CAPD patients.
- Trial name
- NCT00421785
- Testing
- Oral N-Acetylcysteine 1200 mg x 2/day for 4 weeks.
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Assaf-Harofeh Medical Center
Peritoneal Dialysis Catheter Exit Site Infection, End Stage Renal Disease on Dialysis
Chlorhexidine Gluconate-gel Dressing for Exit Site Infection in Peritoneal Dialysis
Exit site infection (ESI) is one of the major predisposing factors to peritoneal dialysis (PD) related peritonitis. Chlorhexidine Gluconate (CHG) has been widely used for cutaneous disinfection for half a century.
- Conditions
- Peritoneal Dialysis Catheter Exit Site Infection, End Stage Renal Disease on Dialysis, Dialysis; Complications
- Trial name
- NCT06022835
- Testing
- Chlorhexidine Gluconate-gel (CHG) Dressing
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- National Healthcare Group, Singapore
End Stage Renal Disease, Continuous Ambulatory Peritoneal Dialysis
Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR
Phase IV post-marketing study to evaluate the effect of Extraneal on the HOMA index in non-diabetic CAPD patients over the long-dwell exchange.
- Trial name
- ECOS (NCT01093547)
- Testing
- Blood samples, Measure of peritoneal ultrafiltrates
- Where
- Colombia
- Sponsor
- Vantive Health LLC
Peritoneal Dialysis Access Failure, Peritoneal Dialysis Complication
Improving the Outcomes of Peritoneal Dialysis (PD) Catheter Insertion
Peritoneal dialysis (PD) is actively promoted as the preferred form of dialysis for patients with kidney failure. However, 1 in 5 patients will experience a signification catheter insertion-related PD catheter complication in the…
- Trial name
- NCT04034628
- Testing
- Peritoneal Catheter Insertion - Laparoscopic, Peritoneal Catheter Insertion - Percutaneous
- Where
- Canada
- Volunteers
- 2,320 people
- Sponsor
- Sunnybrook Health Sciences Centre
End Stage Renal Disease, Peritoneal Dialysis Complication
Reduction of Peritoneal Glucose Uptake With Use of SGLT2 in Humans Undergoing Peritoneal Dialysis Treatment
End stage renal disease is annually diagnosed in about one thousand patients in Denmark, and one of the treatment modalities in renal replacement therapy is peritoneal dialysis with about 25 % of patients assigned to this…
- Trial name
- PRESERVE (NCT05250752)
- Testing
- Dapagliflozin 10 MG [Farxiga]
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Holbaek Sygehus
End Stage Renal Disease, Peritoneal Dialysis
Relationship Between Blood Pressure and Pulse Wave Velocity Measurements in Peritoneal Dialysis
This study evaluates the relationship between Ambulatory Aortic and Branchial blood pressure vs Office blood pressure measurements with the changes in arterial stiffness indices, in long-term Peritoneal Dialysis (PD) patients.
- Conditions
- End Stage Renal Disease, Peritoneal Dialysis, Arterial Sclerosis
- Trial name
- NCT03607747
- Where
- Greece
- Volunteers
- 40 people
- Sponsor
- Aristotle University Of Thessaloniki
End Stage Renal Disease
Comparison of the Impact of Dialysis Treatment Type on Patient Survival
As the influence of type of dialysis on survival of end stage renal disease (ESRD) patients remains unanswered, the present study is designed (randomized, prospective, multicenter, interventional) to assess clinical outcomes, and…
- Trial name
- NCT00510549
- Testing
- Modality: Peritoneal Dialysis
- Where
- 2 sites in China
- Volunteers
- 50 people
- Sponsor
- Baxter Healthcare Corporation
End Stage Renal Disease on Dialysis, Peritoneal Dialysis Complication
Empagliflozin on Residual Kidney Function in Incident Peritoneal Dialysis Patients
Empagliflozin, a new class of diabetes medication, has demonstrated a reduction in renal function decline among patients with chronic kidney disease, regardless of their diabetes status.
- Conditions
- End Stage Renal Disease on Dialysis, Peritoneal Dialysis Complication, Sodium-glucose Cotransporter-2 Inhibitor, Residual Kidney Function
- Trial name
- EMPIRIC-PD (NCT06483074)
- Testing
- Empagliflozin 10 MG
- Where
- Hong Kong
- Volunteers
- 48 people
- Sponsor
- Chinese University of Hong Kong
Chronic Kidney Diseases, Peritoneal Dialysis
Effects of Curcumin Supplementation in Patients With Chronic Kidney Disease on Peritoneal Dialysis
The objective of this study is to assess whether supplementation with curcumin could modulate the intestinal microbiota, reducing levels of inflammatory markers of oxidative stress, uremic toxins and inflammasome, in patients…
- Conditions
- Chronic Kidney Diseases, Peritoneal Dialysis, Hemodialysis
- Trial name
- NCT04413266
- Testing
- Curcumin supplementation
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- Universidade Federal Fluminense
Anemia, Chronic Kidney Disease
Study to Evaluate the Efficacy and Safety of GX-E2 in the Anemic Patients Diagnosed With Chronic Kidney Disease (CKD)
The primary objective of study is Part A : To explore the optimal fixed starting dose and dosing interval of GX-E2 Part B : To evaluate the proof of concept (POC) of GX-E2
- Trial name
- NCT02044653
- Testing
- GX-E2, NESP, MIRCERA
- Where
- 5 sites in South Korea
- Volunteers
- 257 people
- Sponsor
- Genexine, Inc.
End Stage Renal Disease, Insulin Resistance
Effect of an L-carnitine-containing Peritoneal Dialysis (PD) Solution on Insulin Sensitivity in Patients on Continuous Ambulatory Peritoneal Dialysis (CAPD)
The current study is initiated in order to assess the impact of a PD solution containing L-carnitine on insulin sensitivity measured by a hyperinsulinemic euglycemic clamp.
- Trial name
- NCT00755456
- Testing
- PD solution containing glucose, PD solution containing glucose and L-carnitine
- Where
- 12 sites in Italy
- Volunteers
- 35 people
- Sponsor
- Iperboreal Pharma Srl