Clinical trials: Complication of Renal Dialysis
Hyperphosphatemia, Chronic Kidney Disease
A Study of HS219 in Chronic Kidney Disease Patients on Hemodialysis With Hyperphosphatemia
This was a study to evaluate the efficacy and safety of HS219, chitosan-loaded chewing gum, when given three times a day for 3 weeks to the hemodialysis (HD) patients with hyperphosphatemia whose serum inorganic phosphorus was…
- Trial name
- NCT01039428
- Testing
- HS219
- Where
- 11 sites in Japan
- Volunteers
- 68 people
- Sponsor
- KDL Inc.
Renal Disease, Chronic, Hemodialysis Catheter Infection
Evaluation of the Impact of the UPLUG Device Onto the Infection Rate of Indwelling Central Venous Catheters in Patients Undergoing Chronic Hemodialysis
Infections are common complications among patients on chronic haemodialysis. Haemodialysis patients with a catheter have a 2- to 3-fold increased risk of hospitalization for infection and death compared with patients with an…
- Trial name
- UPLUG-EVIDENCE (NCT05670964)
- Testing
- Connecting valve system, Central haemodialysis Venous Catheter
- Where
- France
- Volunteers
- 7 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Nutrition Disorders, Dialysis
Estimate for Dietary Intakes and Hemodialysis Patients
The aim of this clinical research is to evaluate the relevance of using the EPA slide to estimate dietary intakes in dialysis patients.
- Conditions
- Nutrition Disorders, Dialysis, Chronic Renal Failure, Dietetician
- Trial name
- EDDEN (NCT03772171)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Caen
Anaemia, Chronic Kidney Disease (CKD)
Observational Study of Correction of Anaemia With Darbepoetin Alfa at QM Dosing Interval in Patients With CKD Not on Dialysis
To describe anaemia correction via haemoglobin measurements taken throughout observation period in ESA naive patients with chronic kidney disease initiated on darbepoetin alfa QM
- Trial name
- ADAPTATION (NCT02185911)
- Where
- 40 sites in Austria, Bulgaria and 6 more
- Volunteers
- 308 people
- Sponsor
- Amgen
Hemodialysis Access Failure, Hemodialysis Complication
Clinical Values of Mature Fistulas in Hemodialysis
The arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis(HD), and fistula-first is the general recommendation for all HD patients.
- Trial name
- NCT04416971
- Testing
- AVF puncture
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Shanghai Zhongshan Hospital
Chronic Renal Failure
Cost Utility Analysis of Erythropoietin for Anemia Treatment in Hemodialysis Patients
To study the cost utility analysis of Erythropoietin (EPO) for maintaining the different hemoglobin (Hb) target levels in anemic hemodialysis patient in routine clinical practice.
- Trial name
- CUAEPO (NCT01049711)
- Testing
- erythropoietin
- Where
- Thailand
- Volunteers
- 152 people
- Sponsor
- Mahidol University
End Stage Renal Disease, Vascular Access Patency
Determine the Safety/Efficacy of Ticagrelor for Maintaining Patency of Arterio-Venous Fistulae Created for Hemodialysis
This study is a randomized, placebo-controlled, single blind clinical trial. Seventy patients with ESRD on chronic HD and a functioning AVF will be recruited.
- Trial name
- NCT02335099
- Testing
- ticagrelor
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- University of Virginia
Complication of Peritoneal Dialysis
Natural History of Mineral Metabolism Parameters and Protein-bound Toxins in Incident Peritoneal Dialysis Patients
The aims of this study are 1. To evaluate the natural history of plasma concentrations and renal and peritoneal clearances of small water-soluble uremic retention molecules (URM), 'middle molecules', and protein bound URM in…
- Trial name
- NCT01306149
- Where
- Belgium
- Volunteers
- 96 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Renal Disease
Vitamin K2 Supplementation and Vascular Calcification
Vascular calcification is the leading cause of death in patients with end stage renal disease (ESRD) in hemodialysis. The protein matrix Gla vitamin K dependent (MGP) is a potent inhibitor of the vascular calcification.
- Trial name
- NCT04539418
- Testing
- Vitamin K 2
- Volunteers
- 59 people
- Sponsor
- Catholic University of Salta
Fluid Overload, Dialysis; Complications
ULtrafiltration-Rate Induced CArdiac Strain (ULRICA) - Study
Patients performing chronic hemodialysis (HD) retain more or less water between dialyses. The water is removed by ultrafiltration and usually during the cleansing of waste products - the HD.
- Trial name
- ULRICA (NCT06153888)
- Testing
- Ultrafiltration rate
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Umeå University
Renal Insufficiency, Kidney Diseases
A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment
This is a multicenter, open-label, parallel-group study to evaluate INCB054707 in participants with varying levels of renal function or impairment.
- Trial name
- NCT05624710
- Testing
- INCB054707
- Where
- 4 sites in United States, Germany
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Incyte Corporation
Renal Disease, End Stage
β2M Post-HD Rebound Prediction
β2-Microglobulin is small 11.8 kDa protein presents on the surface of all nucleated cell in the human body, it forms part of the non-variable chain of Major Histocompatibility Complex class I.
- Trial name
- NCT07713680
- Testing
- β2-microglobulin blood concentration in mg/L
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- East and North Hertfordshire NHS Trust
Sleep Apnea, End Stage Renal Disease
Impact of Different Dialysis on Sleep Apnea in Patients With Renal Failure
The purpose of this study is to determine whether hemodiafiltration, a new form of hemodialysis can improve sleep apnea in patients with end stage kidney disease.
- Trial name
- NCT00380848
- Testing
- Hemodiafiltration
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
ESRD (End Stage Renal Disease), Dialysis
Laser Acupuncture for Fatigue in Hemodialysis Patients
The goal of this clinical trial is to learn if laser acupuncture (low-level laser therapy) works to treat fatigue and improve quality of life in adults with end-stage renal disease (ESRD) undergoing hemodialysis.
- Conditions
- ESRD (End Stage Renal Disease), Dialysis, Fatigue
- Trial name
- LA-HD-Fatigue (NCT07538310)
- Testing
- Low-Level Laser Acupuncture (LA)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- Taipei City Hospital
Chronic Renal Failure
Post-Marketing Surveillance on Long-Term Drug Use of Kiklin (Bixalomer)® Capsules in Patients With Hyperphosphatemia Receiving Peritoneal Dialysis
To evaluate the safety and efficacy of long-term use of Kiklin® Capsules in actual clinical settings.
- Trial name
- NCT01903213
- Testing
- bixalomer
- Where
- 8 sites in Japan
- Volunteers
- 123 people
- Sponsor
- Astellas Pharma Inc
Pruritus, Kidney Failure, Chronic
Efficacy of Laser Acupuncture on Pruritus in Patients With Chronic Kidney Disease Undergoing Hemodialysis
Uremic pruritus is a clinically significant symptom which imposes heavy impact on the quality of life of patients with chronic kidney disease undergoing hemodialysis.
- Trial name
- NCT02432508
- Testing
- Laser acupuncture (Olympic)
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- China Medical University Hospital
Kidney Failure,Chronic
Safety, Effectiveness and Manipulability Evaluation of a Domestic PD Machine
This study is a randomized, multi-center，crossover study of a domestic FM peritoneal dialysis machine and Baxter HOMECHOICE.It aims to verify safety, effectiveness and manipulability of a domestic peritoneal dialysis machine.
- Trial name
- NCT02525497
- Testing
- FM peritoneal dialysis machine, HOMECHOICE peritoneal dialysis machine
- Where
- China
- Volunteers
- 360 people
- Sponsor
- Chinese PLA General Hospital
End Stage Renal Disease, Cardiovascular Disease
Pomegranate and Hemodialysis Pilot Trial
In this study, the investigators will administer pomegranate juice or fruit extract as a targeted antioxidant therapy to hemodialysis patients.
- Conditions
- End Stage Renal Disease, Cardiovascular Disease, Inflammation
- Trial name
- POM Pilot (NCT01562340)
- Testing
- Pomegranate juice, Pomegranate fruit extract
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Washington
Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD)
Pharmacokinetics of Meropenem and Aztreonam After Intraperitoneal Administration Via Cycler-therapy in APD Patients Without Peritonitis
Peritoneal dialysis-associated peritonitis (PDAP) remains one of the most serious complications in patients undergoing peritoneal dialysis (PD), contributing significantly to hospitalization, technique failure, and mortality.
- Conditions
- Peritoneal Dialysis Associated Peritonitis, Peritoneal Dialysis (PD), Peritoneal Dialysis, Peritoneal Dialysis, Continuous Ambulatory
- Trial name
- NCT07113574
- Testing
- Meropenem 1000 mg, Aztreonam 2000 mg, automated peritoneal dialysis with following long time dwell
- Where
- Austria
- Volunteers
- 12 people
- Sponsor
- Karl Landsteiner Insitute for Nephrology and Haemato-Oncology
End Stage Renal Disease, Continuous Ambulatory Peritoneal Dialysis
Open-label, Randomized Trial to Determine the Effect of Icodextrin Versus Dextrose (Dianeal 2.5%) in HOMA IR
Phase IV post-marketing study to evaluate the effect of Extraneal on the HOMA index in non-diabetic CAPD patients over the long-dwell exchange.
- Trial name
- ECOS (NCT01093547)
- Testing
- Blood samples, Measure of peritoneal ultrafiltrates
- Where
- Colombia
- Sponsor
- Vantive Health LLC