Clinical trials: Complications, Postoperative
Staphylococcal Aureus Infection, Surgical Site Infection (SSI)
Gene Expression Analysis of Biofilm Formation and Antimicrobial Resistance in Clinical Methicillin-Resistant Staphylococcus Aureus
Staphylococcus aureus are Gram-positive cocci that asymptomatically colonize the skin and mucosal surfaces of approximately 20-30% of healthy individuals . Although they commonly exist as a harmless commensal organisms, S.
- Trial name
- NCT07796555
- Testing
- swab from lesion, Biochemical reactions, Antibiotic sensitivity
- Volunteers
- 100 people
- Sponsor
- Sohag University
Pain, Postoperative
Bilateral Transversus Abdominis Plane Block With or Without Magnesium
Pain control after surgery is important for patient well-being and recovery. We are interested in determining whether we can improve the duration of action of a local anesthetic procedure (transversus abdominis plane block, or…
- Trial name
- NCT02680626
- Testing
- Magnesium Sulfate, Ropivacaine
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Dr. Anthony Ho
Spinal Fusion, Transfusion
Effect of Intraoperative Allogeneic Blood Transfusion on Postoperative Pulmonary Complications
Elective spine surgery is associated with a high incidence of perioperative complications, including peri- and postoperative pulmonary complications (PPCs), which occur in nearly 4% of patients.
- Conditions
- Spinal Fusion, Transfusion, Pulmonary Complication
- Trial name
- NCT05661838
- Testing
- transfusion
- Where
- China
- Volunteers
- 272 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pain, Post-operative
Serratus Anterior Plane Block in Patients Undergoing Mastectomy
This is a randomized, interventional prospective study. Patients (n=66) undergoing mastectomies with or without tissue expander will be randomized to receive a supra-serratus or sub-serratus regional plane block prior to surgery.
- Trial name
- NCT03154658
- Testing
- Ropivacaine 0.35%
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Texas Southwestern Medical Center
Cholecystectomy, Laparoscopic, Pain, Postoperative
Transversus Abdominis Plane Block (TAP) for Laparoscopic Cholecystectomy Surgery
Postoperative pain is a significant cause of increased morbidity in the perioperative period, leading to patient discomfort and greater hospital length of stay.
- Trial name
- NCT02185716
- Testing
- Levobupivacaine 0.25 %, Levobupivacaine 0.5%
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Duzce University
Postoperative Infection, Geriatrics
Postoperative Infectious Complications Calculator for Elderly Patients
The investigators established a first-ever convenient scoring system for clinicians to assess the risk of Postoperative infectious complications (PICs) for elderly patients.
- Conditions
- Postoperative Infection, Geriatrics, Prediction
- Trial name
- NCT06265493
- Where
- China
- Volunteers
- 37,230 people
- Sponsor
- Weidong Mi
Peripheral Vascular Diseases
General Versus Regional Anaesthesia in Peripheral Arterial Surgery: Incidence of Postoperative Pulmonary Complications.
The study will be designed as a prospective clinical trial. Patients scheduled for lower limb arterial bypass surgery will be randomly allocated for treatment with spinal anesthesia associated with spontaneous ventilation (nasal…
- Trial name
- NCT04566016
- Testing
- Regional anesthesia
- Where
- Brazil
- Volunteers
- 120 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Post Operative Pain
Too Much of a Good Thing? Impact of Initial Prescription Size in Post-cesarean Section Pain Management
This is a randomized controlled trial involving 170 opioid naive women ages 19-40 undergoing scheduled C-sections at Carilion Roanoke Memorial Hospital.
- Trial name
- NCT05360433
- Testing
- Oxycodone oral capsule
- Where
- United States
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Carilion Clinic
Inguinal Hernia, Indirect, Postoperative Pain
Comparison of Postoperative Pain After Hernial Sac Ligation Versus Non-ligation in Inguinal Hernioplasty
This study is intends to compare mean postoperative pain scores for 48-hours in patients undergoing Inguinal hernioplasty with and without hernia sac ligation in Department of Surgery, Dow University of Health Sciences \& Dr.
- Trial name
- NCT04079504
- Testing
- Ligation of indirect hernia sac, Non-ligation of Indirect Inguinal hernia sac
- Where
- Pakistan
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Cervical Cancer
A Safety and Efficacy of CCRT With Paclitaxel/Carboplatin as Adjuvant Therapy to Post-operative Cervical Cancer Patients
The purpose of this study is to determine whether post-operative concurrent chemoradiation with paclitaxel/carboplatin is effective and safe in the treatment of high risk cervical cancer patients.
- Trial name
- NCT00340184
- Testing
- paclitaxel, carboplatin
- Where
- South Korea
- Volunteers
- 55 people
- Sponsor
- Korean Gynecologic Oncology Group
Aortic Valve Stenosis, Aortic Valve Regurgitation
Valve Hemodynamic Optimization Based on Doppler-Echocardiography vs Catheterization Measurements Following ViV TAVR
Data on valve performance following ViV-TAVR has usually been obtained with the use of Doppler-echocardiography. However, some reports have shown significant discordances in the evaluation of mean transvalvular gradient between…
- Conditions
- Aortic Valve Stenosis, Aortic Valve Regurgitation, Prosthesis Failure
- Trial name
- ECHOCATH (NCT05459233)
- Testing
- Doppler-echocardiography, Invasive hemodynamic measurements
- Where
- 7 sites in United States, Canada
- Volunteers
- 310 people
- Sponsor
- Institut universitaire de cardiologie et de pneumologie de Québec, University Laval
Stone;Renal, Stone, Kidney
Ureteral Stenting After Ureteroscopy for Stone Treatment, A Global Perspective on Indications and Outcomes
Background: The exit strategy after ureteroscopy for stone treatment remains a topic for discussion. Current EAU guidelines on urolithiasis state that postoperative stenting is indicated in patients at increased risk of…
- Conditions
- Stone;Renal, Stone, Kidney, Stone Ureter
- Trial name
- NCT03567421
- Where
- 50 sites in United States, China and 13 more
- Volunteers
- 2,348 people, healthy volunteers welcome
- Sponsor
- Société Internationale d'Urologie
Postoperative Pain, Acute
Effectiveness of Pain Control and Adverse Reactions After Intravenous PCA in Chinese Population
Here, we retrospectively analyzed the proportion of intravenous patient controlled analgesia (PCA) used in a large tertiary hospital in central China, and then further analyzed the proportion of patients with postoperative pain…
- Trial name
- NCT05884021
- Testing
- Postoperative analgesia
- Volunteers
- 40,000 people
- Sponsor
- Huazhong University of Science and Technology
Postoperative Nausea and Vomiting
Combination Antiemetic Regimen for Prevention of PONV in Breast Surgery Patients
The purpose of this study is to compare the efficacy of the use of oral aprepitant in combination with intravenous ondansetron and dexamethasone with the efficacy provided by the use of oral aprepitant and dexamethasone for…
- Trial name
- NCT00738621
- Testing
- Aprepitant, Dexamethasone, Ondansetron
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Scott and White Hospital & Clinic
Hemorrhoids Second Degree, Hemorrhoids Third Degree
Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids
Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain.
- Conditions
- Hemorrhoids Second Degree, Hemorrhoids Third Degree, Internal Hemorrhoids
- Trial name
- LHP-MMH (NCT07678814)
- Testing
- Laser Hemorrhoidoplasty, Milligan Morgan Hemorrhoidectomy
- Where
- Pakistan
- Volunteers
- 96 people
- Sponsor
- Allama Iqbal Medical College
Postoperative Pain
Topical Ketamine Analgesia in Children Undergoing Tonsillectomy: a Clinical and Serum Level Assays Study.
The aim of this study is to evaluate the analgesia efficacy of local ketamine given by two different doses in pediatric patients undergoing tonsillectomy operations
- Trial name
- NCT02720406
- Testing
- Intravenous ketamine0.5mg/kg, Nebulized Ketamine 1mg/kg, Nebulized Ketamine 2mg/kg
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Gynecologic Disease, Postoperative Ileus
Postoperative Chewing Gum and Gynecological Laparoscopic Surgery
The authors aimed to evaluate the effects of postoperative gum chewing on laparoscopic gynecological surgery, gastrointestinal function-intestinal mobility and early postoperative recovery.
- Conditions
- Gynecologic Disease, Postoperative Ileus, Paralytic Ileus
- Trial name
- NCT03884244
- Testing
- chewing gum
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Pain, Postoperative
Virtual Reality for Post Operative Pain
Randomized controlled trial to measure pain experience, side effects and satisfaction of VR following varicose vein, hernia repair and gallbladder surgeries.
- Trial name
- VRppain (NCT03776344)
- Testing
- Virtual Reality intervention - Oculus Rift HD
- Where
- Romania
- Volunteers
- 62 people
- Sponsor
- Babes-Bolyai University
Postoperative Pain, Opioid Use
Improving Post-Operative Pain and Recovery in Gynecologic Surgery
This is a clinical investigation to determine the efficacy of rectal versus intravenous acetaminophen in patients undergoing a minimally invasive hysterectomy.
- Conditions
- Postoperative Pain, Opioid Use, Acetaminophen
- Trial name
- NCT04175509
- Testing
- Rectal acetaminophen, Intravenous acetaminophen
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Aultman Health Foundation
Patient Safety, Intraoperative Complications
Validation Study of ClassIntra®
Whereas there are several validated systems for reporting postoperative complications, there are only a few and not prospectively validated systems for reporting intraoperative complications.
- Conditions
- Patient Safety, Intraoperative Complications, Postoperative Complications, Risk Management
- Trial name
- ClassIntra® (NCT03009929)
- Testing
- Observational study
- Where
- 18 sites in United States, Australia and 10 more
- Volunteers
- 2,500 people
- Sponsor
- University Hospital, Basel, Switzerland
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