Clinical trials: Complications, Postoperative
Postoperative Pain
Double Lock Versus Continuous Non-locking Technique for Closure of Rectus Sheath in Cesarean Sections on Post-operative Pain
In this trial we compare the effect of 2 closure techniques of the rectus sheath during cesarean sections on postoperative pain.
- Trial name
- NCT02679365
- Testing
- lower segment cesarean section and double lock closure of rectus sheath, lower segment cesarean section and continuous non-locking closure of rectus sheath
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Surgical Wound Infection
Supplemental Perioperative Oxygen to Reduce the Incidence of Post-cesarean Wound Infection
The purpose of this study is to determine if the use of supplemental oxygen at 80% FIO2 can reduce the incidence of surgical site infection after emergency cesarean section.
- Trial name
- NCT01340534
- Testing
- Supplemental oxygen 80% FIO2, Use of air (no oxygen during surgery)
- Where
- Panama
- Volunteers
- 370 people
- Sponsor
- Saint Thomas Hospital, Panama
Postoperative Pain
Pain Control of Thoracoscopic Major Pulmonary Resection
The purpose of this study is to evaluate whether pre-emptive local bupivacaine injection is a better alternative pain control modality than the conventional intravenous patient controlled analgesia.
- Trial name
- NCT01758809
- Testing
- Pre-emptive bupivacaine wound infiltration, intravenous patient controlled analgesia
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Bundang Hospital
Therapy, Pain Management
Intrathecal Ketamine, Dexmedetomidine and Both With Bupivacaine for Postoperative Abdominal Cancer Surgery Pain
Currently, opioids are widely used for pain relief, but they often provide sub-optimal analgesia with occasional serious side effects.
- Trial name
- NCT02455609
- Testing
- intrathecal drug administration, Dexmedetomidine, ketamine
- Volunteers
- 90 people
- Sponsor
- Assiut University
Blood Platelet Disorders, Cardiac Surgery
Observational Study of Platelet Dysfunction Assessed by Thromboelastography in Cardiovascular Surgery (DISPLATEG)
Perioperative bleeding requiring blood transfusion is common during cardiovascular surgery, especially in procedures requiring cardiopulmonary bypass. Adenosine diphosphate (ADP) plays a fundamental role in platelet function.
- Conditions
- Blood Platelet Disorders, Cardiac Surgery, Postoperative Bleeding
- Trial name
- DISPLATEG (NCT06961175)
- Where
- Spain
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León
Cardiac Disease, Bleeding Postoperative
Fresh Autologous Whole Blood Transfusion After Cardiopulmonary Bypass
Autologous blood transfused at the end of cardiopulmonary bypass will reduce total blood loss 24 hours after surgery and improve mitochondrial oxygen delivery measured by plasma succinate levels.
- Trial name
- NCT03204357
- Testing
- Fresh Autologous whole Blood, Standard of Care Expectant management of bleeding
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Colorado, Denver
Neoplasm, Hepatic, Pancreatic Neoplasms
Impact of Microparticles on Postoperative Complications in Surgical Patients
Microparticles are cellular fragments which are released actively or passively under conditions of inflammation and stress. The impact of surgical operations on quantity and quality of microparticles remains unknown.
- Conditions
- Neoplasm, Hepatic, Pancreatic Neoplasms, Colorectal Neoplasms
- Trial name
- NCT00677781
- Where
- Switzerland
- Volunteers
- 108 people
- Sponsor
- University of Bern
Prosthesis-related Infections, Wound Complications
Evaluation of Wound Management With Negative Pressure Dressing Versus Standard Dressing After Revision Arthroplasty.
The purpose of this study is to determine the efficacy of a negative pressure wound therapy (NPWT) system after revision total knee and hip arthroplasty in patients at high risk for infection.
- Conditions
- Prosthesis-related Infections, Wound Complications, Joint Diseases, Musculoskeletal Diseases
- Trial name
- NCT02127281
- Testing
- Prevena
- Where
- United States
- Volunteers
- 160 people
- Sponsor
- The Cleveland Clinic
Postoperative Pain
3-midline-ports Cholecystectomy
The 3-midline-ports technique is a safety approach and associates lower postoperative pain, when compared with the standard "French" technique.
- Trial name
- NCT01378819
- Testing
- 3-midline-ports laparoscopic cholecystectomy
- Volunteers
- 100 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Pain, Shoulder, Post Operative Pain
The Role of Neurofeedback Training and Pain Management in Post-operative Shoulder Rehabilitation
The primary aim is to compare the efficacy of neurofeedback training (NFT) and pain management protocol (PMP) in pain reduction, restoration of shoulder function, and improved cognitive performance as the post-operative…
- Trial name
- NCT05948007
- Testing
- Neurofeedback training, Pain management protocol
- Sponsor
- Chang Gung Memorial Hospital
Postoperative Complications
Local and Intraperitoneal Analgetics in Gynecologic Laparoscopy for Post Operative Pain Relief
A comparison between local and intraperitoneal analgetics to placebo, during laparoscopy, regarding post operative pain.
- Trial name
- NCT02976571
- Testing
- Bupivacaine
- Where
- Israel
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Wolfson Medical Center
Postoperative Pain
Lumbar Erector Spinae Plane Block and Quadratus Lumborum Block in Hip and Proximal Femur Surgeries
Multimodal analgesia is used to control postoperative pain in hip surgery. Quadratus lumborum block is an effective regional anesthesia technique for hip and proximal femur surgery.
- Trial name
- NCT03508544
- Testing
- Lumbar ESP block, QLB bLock, Standard Pain Followup and Monitorization
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Maltepe University
Rectal Cancer, Surgery Indication
Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)
The objectiive of this prospective, international cohort is to compare two anastomotic techniques (DS vs TTSS) by collecting data during the surgery, and postoperatively (morbidity and functional outcomes).
- Trial name
- OASIS (NCT07146334)
- Where
- 15 sites in Belgium, Canada and 4 more
- Volunteers
- 400 people
- Sponsor
- Bordeaux Colorectal Institute
Atrial Fibrillation Rapid, Postoperative Complications
Preoperative Carbohydrate Load and Intraoperative w3-PUFA in CAGB Surgery
Omega-3 polyunsaturated fatty acids (w-3-PUFA) may have a potential role in enhance the postoperative balance of host immunity and reduce the incidence of postoperative atrial fibrillation (POAF).
- Trial name
- NCT03017001
- Testing
- CHO (carbohydrate), intravenous w-3 PUFA, CHO (carbohydrate) plus intravenous w3-PUFA
- Volunteers
- 60 people
- Sponsor
- Federal University of Mato Grosso
Postoperative Pain, Acute, Emergence Delirium
Comparing Ketamine and Fentanyl in Pediatric Tonsillectomy: Pain Control and Emergence Delirium Outcomes (KVFPT)
This study is designed to compare the effectiveness of two medications, ketamine and fentanyl, in managing pain and preventing delirium in children aged 3 to 8 years who are undergoing tonsillectomy and adenoidectomy surgery.
- Trial name
- KVFPT (NCT06630364)
- Testing
- ketamine, fentanyl
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Medipol University
Blood Loss, Surgical, Blood Loss, Postoperative
Comparison Study of Oxytocin Versus Tranexamic Acid and Etamsylaye Versus Placebo(Saline)
Comparison Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate Versus Normal Saline as Pre-operative Administration.
- Trial name
- NCT05273632
- Testing
- Oxytocin
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Postoperative Pain
Deep Subgluteal Block vs PENG Combined With LFCN Block for Analgesia After Hip Arthroplasty
This randomized, prospective study aims to compare the clinical efficacy of ultrasound-guided Deep Subgluteal Block (DSGB) versus Pericapsular Nerve Group (PENG) block combined with Lateral Femoral Cutaneous Nerve (LFCN) block…
- Trial name
- DSG-PENG (NCT07770932)
- Testing
- 0.25% Bupivacaine for Deep Subgluteal Block, 0.25% and 0.125% Bupivacaine for PENG+LFCN Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Medipol University
Bleeding, Postoperative Complications
Effect of Clips Versus Omentopexy on Postoperative Bleeding
In this prospective randomized study, patients were divided into two groups: clips group and omentopexy group. The groups were compared in terms of postoperative decrease in hemoglobin and hematocrit values, preoperative and…
- Conditions
- Bleeding, Postoperative Complications, Postoperative Nausea and Vomiting
- Trial name
- NCT06211699
- Testing
- Omentopexy with Laparoscopic Sleeve Gastrectomy, Clips with Laparoscopic Sleeve Gastrectomy
- Where
- Turkey (Türkiye)
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Umraniye Education and Research Hospital
Postoperative Pain
Adjuvants With Intrathecal Bupivacaine for Postoperative Analgesia
The aim of this study is to compare the postoperative analgesic effect of intrathecal dexmedetomidine combined with bupivacaine and midazolam combined with bupivacaine in high tibial osteotomy.
- Trial name
- NCT06082232
- Testing
- Dexmedetomidine, Midazolam, Bupivacain
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiac Flow
Decrease of Post-operative Complications by SCVO2 Monitoring an Optimisation of Cardiac Flow
In operating theater, one of the bigger purpose of anesthetist-resuscitator is to optimize vascular filling (VF) because of a failure or an excess of filling is deleterious for the patient.
- Trial name
- OCOSO2 (NCT03828565)
- Testing
- ScvO2 Perioperative continue monitoring
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
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