Clinical trials: Complications, Postoperative
Postoperative Pain
Comparison of Interpectoral+Serratus Anterior Block With Erector Spinae Block in Minimally Invasive Cardiac Surgery
Adequate pain management after minimally invasive cardiac surgery is essential for early ambulation and patient satisfaction. However, an incision similar to thoracotomy surgery is made by entering between the ribs, and a…
- Trial name
- NCT05743231
- Testing
- interpectoral area block + serratus anterior area block group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Achalasia
Post Operative Pain Control of POEM Procedure
Peroral endoscopic myotomy (POEM) is a minimally invasive treatment for esophageal achalasia with a natural orifice transluminal endoscopic procedure and far less invasive than the standard surgical or laparoscopic Heller myotomy…
- Trial name
- NCT04177342
- Testing
- Fentanyl, Oxycodone
- Volunteers
- 196 people
- Sponsor
- Chen Wannan
Low Anterior Resection Syndrome
The Effects of Colorectal Prehabilitation Via Reinfusion or Retention Enema of Ileal Contents Filtrate on the Defecation Functions for the LAR Patients With Ileostomy Before Stoma Closure
This study was a single-center RCT study to compare the effect of preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon with that of traditional…
- Trial name
- NCT06569966
- Testing
- preoperative prehabilitation treatment of ileostomy contents filtrate reinfusion through distal ileocolon or retention of enema colon
- Where
- China
- Volunteers
- 154 people
- Sponsor
- The Affiliated Hospital of Qingdao University
Postoperative Pain, Cardiac Surgery
The Effect of Acupressure Application on Respiratory Performance and Pain Levels in Adult Patients Undergoing Cardiac Surgery
The purpose of this randomized controlled trial is to evaluate the effect of acupressure on respiratory performance and pain levels in adult patients who have undergone open-heart surgery.
- Conditions
- Postoperative Pain, Cardiac Surgery, Postoperative Complications
- Trial name
- NCT07771751
- Testing
- Acupressure, Incentive spirometry
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people
- Sponsor
- Fenerbahce University
Postoperative Nausea and Vomiting (PONV)
Granisetron Combined With Dexamethasone or Metoclopramide for PONV Prevention After Laparoscopic Cholecystectomy
Postoperative nausea and vomiting (PONV) remain common and distressing complications following laparoscopic cholecystectomy, particularly in female patients.
- Trial name
- NCT07360431
- Testing
- Granisetron
- Volunteers
- 102 people
- Sponsor
- Assiut University
Postoperative Vasoplegic Syndrome
Small Doses of Pituitrin Versus Norepinephrine for the Management of Vasoplegic Syndrome in Patients After Cardiac Surgery
Vasoplegic syndrome is a common complication after cardiac surgery. Low dose vasopressin can up-regulate blood pressure and improve clinical outcomes compared with norepinephrine (mainly acute kidney injury Anesthesiology 2017…
- Trial name
- NCT03106831
- Testing
- Pituitrin infusion, Norepinephrine infusion
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Beijing Anzhen Hospital
Pain, Postoperative, Opioid Use
Impact of Counseling and Education on Opioid Consumption After ACL Reconstruction
Research question: Does an opioid limiting pain management counseling and education program result in decreased opioid consumption and improved pain control compared to traditional pain management programs after anterior cruciate…
- Trial name
- CARE (NCT04885231)
- Testing
- Perioperative Pain Management Education and Counseling
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- University of Maryland, Baltimore
Postoperative Pain
Postoperative Discomfort After Dental General Anesthesia
The aim of this prospective, randomised, controlled clinical trial was to compare immediate postoperative discomfort, emergence delirium and recovery time of the patients intubated using either laryngeal mask airway or…
- Trial name
- NCT03197753
- Testing
- Laryngeal mask airway, Nasotracheal intubation
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Ventral Hernia, Incisional Hernia
The Impact of Abdominal Wall Reconstruction on Abdominal Wall Tension and Intra-Abdominal Pressure
This is a prospective cohort study. Patients have an incisional or parastomal hernia with >20 cm fascial defect on pre-operative imaging who will undergo an anticipated open bilateral transversus abdominis release with…
- Conditions
- Ventral Hernia, Incisional Hernia, Parastomal Hernia
- Trial name
- NCT06575166
- Testing
- Abdominal wall tension, Intra-abdominal pressure
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Acute Kidney Injury
Association Between Muscular Tissue Oxygen Saturation and AKI in Older Patients Undergoing Major Abdominal Surgery
The aim of this study is to investigate association between muscular oxygen saturation and postoperative acute kidney injury(AKI) in older patients undergoing abdominal surgeries.The investigator also intend to explore the…
- Trial name
- NCT04954066
- Where
- China
- Volunteers
- 253 people
- Sponsor
- General Hospital of Ningxia Medical University
İnguinal Hernia, Complication,Postoperative
Post-Surgical Outcomes of Conventional vs 3-Point Mesh Fixation in Lichtenstein Repair: An RCT
This is a single-center, parallel-group randomized controlled trial conducted in 2025-2025 at the General Surgery Ward of the Sindh Institute of Urology and Transplantation (SIUT), Karachi.
- Conditions
- İnguinal Hernia, Complication,Postoperative, Pain, Postoperative
- Trial name
- COMET (NCT07334548)
- Testing
- 3-point mesh fixation, Conventional Mesh Fixation
- Where
- Pakistan
- Volunteers
- 64 people
- Sponsor
- Sahar Mughis
Postoperative Pain
The Effect of Intraoperative Magnesium Sulfate Infusion on the Postoperative Recovery
Evaluating analgesic effect of intraoperative magnesium sulfate infusion in the outpatient surgery case
- Trial name
- NCT03206008
- Testing
- Magnesium Sulfate, Normal saline
- Where
- South Korea
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Seoul National University Bundang Hospital
Pain, Postoperative
Nefopam for Post Video-Assisted Thoracoscopic Lobectomy
Video-assisted thoracoscopic (VATs) lobectomy is mild to moderately pain procedure. For conventional thoracotomy, there are many invasive pain control such as epidural analgesia, paravertebral block.
- Trial name
- NCT04241640
- Testing
- Nefopam 20 MG/ML
- Where
- Thailand
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Postoperative Pain Management
Ultrasound-Guided Versus Laparoscopy-Guided Transversus Abdominis Plane Block for Postoperative Analgesia
This prospective, randomized, double-blind study aimed to compare the effects of ultrasound-guided versus laparoscopy-guided transversus abdominis plane(TAP) block on postoperative analgesia in patients undergoing laparoscopic…
- Trial name
- US-LTAP (NCT07352189)
- Testing
- Ultrasound-guided Transversus Abdominis Plane (US-TAP) Block, Laparoscopy-guided Transversus Abdominis Plane (LS-TAP) Block
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital
Cesarean Section
Sharp Versus Blunt Fascial Incision at Caesarean Section
The purpose of this study is to compare sharp and blunt fascial entry during caesarean section on the same patient. The study is performed on woman having cesarean section for the first time and who have not previously had lower…
- Trial name
- NCT01297725
- Testing
- Blunt right, sharp left, Blunt left, sharp right
- Where
- 2 sites in Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Holbaek Sygehus
Delirium - Postoperative, Hip Fracture Surgeries
DEX-HIP Trial: Preoperative IV Dexamethasone 4 mg vs Placebo to Reduce Postoperative Delirium Burden in Adults ≥70 Undergoing Hip Fracture Surgery
This single-center, prospective, randomized, double-blind, placebo-controlled trial was conducted at the Department of Orthopaedic Surgery, JPMC, Karachi.
- Conditions
- Delirium - Postoperative, Hip Fracture Surgeries, Steroid
- Trial name
- NCT07651150
- Testing
- Dexamethasone
- Where
- Pakistan
- Volunteers
- 120 people
- Sponsor
- Jinnah Postgraduate Medical Centre
Pathology
Routine Pathological Examination of Hernia Sac; Is it a Workload or Necessary?
Routine microscopic examination of the hernia sac is controversial. While some centers do not recommend a routine microscopic examination in inguinal hernias in adult patients, they recommend them in abdominal wall hernias.
- Trial name
- NCT04383249
- Testing
- Pathology result
- Where
- Turkey (Türkiye)
- Volunteers
- 437 people
- Sponsor
- Dr. Ersin Arslan Education and Training Hospital
Pain, Postoperative, Femur Fracture
Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures
The purpose of this study is to determine the efficacy and safety of a peri-incisional multimodal injection for post-operative pain control following operative management of femur fractures.
- Trial name
- NCT02793947
- Testing
- Ropivacaine, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of Iowa
Pain, Post-operative
Efficacy, Safety and Tolerability Study of Meloxicam Injection in Subjects After Abdominal Surgery
The purpose of this study is to determine the analgesic efficacy and safety of Meloxicam Injection in subjects undergoing abdominal surgery.
- Trial name
- NCT05950152
- Testing
- Meloxicam Injection 30mg, Meloxicam Injection 60mg, Nacl 0.9%
- Where
- China
- Volunteers
- 108 people
- Sponsor
- Beijing Tide Pharmaceutical Co., Ltd
Short Bowel Syndrome (SBS)
A Survey to Assess Participants' and Physicians' Knowledge When Using GATTEX (Knowledge Assessment Survey)
The study is about learning and documenting how well participants and physicians understand how to use GATTEX and about potential risks by using a survey (called Knowledge Assessment Survey).
- Trial name
- NCT05561647
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Takeda
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