Clinical trials: Complications of Medical Care
Diabetes Mellitus Type 2
CDRM Study: Computer-assisted Diabetes Risk Management-for Secondary and Tertiary Prevention of T2DM Complications
The CDRM study will evaluate a newly developed approach to improve management and secondary prevention in diabetes care. The research will explore the impact of an medical care intervention via a computer-assisted diabetes risk…
- Trial name
- CDRM_DMP (NCT01556529)
- Testing
- risk profile information, standard DMP care
- Where
- Germany
- Volunteers
- 405 people
- Sponsor
- Philipps University Marburg
Cancer, Metastatic, Cancer
SYNERGY-AI: Artificial Intelligence Based Precision Oncology Clinical Trial Matching and Registry
International registry for cancer patients evaluating the feasibility and clinical utility of an Artificial Intelligence-based precision oncology clinical trial matching tool, powered by a virtual tumor boards (VTB) program, and…
- Conditions
- Cancer, Metastatic, Cancer, Cancer of Pancreas, Cancer of Liver
- Trial name
- NCT03452774
- Testing
- Clinical Trial Matching
- Where
- 68 sites in United States, Puerto Rico
- Volunteers
- 50,000 people
- Sponsor
- Massive Bio, Inc.
Complication of Surgical or Medical Care
Incidence, Predictors and Validation of Risk Scores to Predict Myocardial Infarction After Noncardiac Vascular Surgery
Evaluate the incidence and predictors of post-operative mortality after noncardiac Vascular Surgery and compare the performance of existing risk scores.
- Trial name
- NCT04051749
- Testing
- Noncardiac Vascular Surgery
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Preterm Infant, Infant, Newborn
Neonatal Wireless Monitoring System for Intensive Care
Babies who require intensive care need to have their heart rate, oxygen levels and temperature measured continuously using specially designed monitors.
- Conditions
- Preterm Infant, Infant, Newborn, Low; Birthweight, Extremely (999 Grams or Less)
- Trial name
- NCT04241263
- Testing
- Wireless vital sign monitoring - comparative, Wireless vital sign monitoring - usability
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Diabetic Foot Ulcer
Oral BBR-012 in the Treatment of Diabetic Foot Ulcers, Proof of Concept Study
The aim of this Clinical Proof of Principle study is to evaluate the effect of BBR-012 on the healing of complicated diabetic foot ulcers.
- Trial name
- BBR-012 (NCT01342497)
- Testing
- isoniazide
- Where
- 11 sites in United Kingdom
- Volunteers
- 60 people
- Sponsor
- Bridge BioResearch Ltd.
Fear, Pain Management
Influence of Preoperative Fear on Pain and Postoperative Outcomes
Fear of anesthesia plays a crucial role in the perioperative setting and can negatively affect recovery. The main objective is to assess the relationship between fear of anesthesia, surgeries, and hospitals and poorer…
- Conditions
- Fear, Pain Management, Anxiety, Complications of Surgical Procedures or Medical Care
- Trial name
- POSPoFe (NCT06785389)
- Testing
- Fear of anesthesia, surgery and hospitals scale, State-Trait Anxiety Inventory, Nummerical Rating Scale for postoperative pain
- Where
- Spain
- Volunteers
- 138 people
- Sponsor
- Hospital Universitario de Gran Canaria Doctor Negrín
Neuromuscular Blockade, Human Characteristics
Sparing in Neuromuscular Blockade in COVID 19 ICU
This is a retrospective case-controlled study of the effect of the use of a neuromuscular blockade (NMB) monitor on the consumption of NMB agents in patients under mechanical ventilation in the context of COVID-19.
- Conditions
- Neuromuscular Blockade, Human Characteristics, Complication of Medical Care, Intensive Care Unit Acquired Weakness
- Trial name
- TOF-COVID (NCT04459533)
- Testing
- TOF protocol
- Where
- France
- Volunteers
- 250 people
- Sponsor
- Hospices Civils de Lyon
Hypotension, Hypoxemia
Point of Care Ultrasound Evaluation in the Post-Anesthesia Unit
The purpose of this observational research study is to examine how point-of care ultrasound affects the workup and management of perioperative complications for specific clinical scenarios of low blood pressure (hypotension), low…
- Conditions
- Hypotension, Hypoxemia, Altered Mental Status, Urine Output Low
- Trial name
- NCT04410757
- Where
- United States
- Volunteers
- 128 people
- Sponsor
- Loma Linda University
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Chronic Kidney Disease
Automated Clinical Reminders in the Care of Chronic Kidney Disease Patients
To determine whether the use of educational sessions and computerized clinical reminders can improve primary care doctors' delivery of care to CKD patients compared to educational sessions alone.
- Trial name
- ACRinCKD (NCT00688285)
- Testing
- automated clinical alerts, provider education
- Where
- United States
- Volunteers
- 248 people
- Sponsor
- University of Pittsburgh
Colon Cancer, Breast Cancer
Understanding the Value of Community Vital Signs in Primary Care
Social determinants of health (e.g. the income, education, and environment of patients) may exert greater influence on health outcomes than traditional clinical factors (e.g. lab results, diagnoses, and family history).
- Conditions
- Colon Cancer, Breast Cancer, Cervical Cancer, Prostate Cancer
- Trial name
- NCT02512835
- Testing
- Community vital signs
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Virginia Commonwealth University
Premature Birth
Use of Dynamic Elastometric Body in Preterm Newborns
The goal of this prospective pilot study is to test the use of dynamic elastomeric body in a population of preterm newborns with hyperexcitability syndrome.
- Trial name
- BODYNEO (NCT05835765)
- Testing
- Dynamic Elastometric Body in Preterm Newborns
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Digestive System Neoplasms, Surgery
Observatory of the Quality of Surgical Procedures for Digestive Cancers
Surgery for digestive cancers is managed according to quality standards, validated by the scientific community. Despite the diffusion of these standards through the benchmarks of good practice, the results of the surgery remain…
- Conditions
- Digestive System Neoplasms, Surgery, Surgery--Complications, Quality of Health Care
- Trial name
- Obchir (NCT03681600)
- Where
- 4 sites in Morocco
- Volunteers
- 1,043 people
- Sponsor
- Moroccan Society of Surgery
Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia
Relief Efficacy of Lidocaine Versus Morphine for Acute Renal Colic in the Emergency Department
The opioid epidemic continues to be a major public health crisis in the United States. According to the Center for Disease Control, approximately 8 million Americans reported misusing prescription opioids in 2023, with over 5…
- Conditions
- Renal Colic, Kidney Stones, Urolithiasis, Hypocitraturia, Opioid Use During Medical Care
- Trial name
- RELIEF-RC (NCT07536594)
- Testing
- Lidocaine, Morphine 0,1 mg/kg
- Volunteers
- 250 people
- Sponsor
- Loma Linda University
Incomplete Abortion, Intrauterine Contraception
Ideal Timing of Intrauterine Contraception Insertion After Medical Management of First Trimester Incomplete Abortion
Background: Unintended pregnancies continue to cause a public health threat in Low and Middle Income countries yet with restrictive abortion laws.
- Conditions
- Incomplete Abortion, Intrauterine Contraception, Misoprostol
- Trial name
- PAIC (NCT05343546)
- Testing
- Use of either copper T380A or Levonorgestrel LNG 52 IUS after medical management of first trimester incomplete abortion
- Where
- Uganda
- Volunteers
- 2,076 people
- Sponsor
- Makerere University
Diabetic Kidney Disease, Type 2 Diabetes
Improving Kidney Care in Type 2 Diabetes: A Study of Pharmacist Prescribing Versus Usual Care
Type 2 diabetes is the leading cause of chronic kidney disease, which can result in serious complications such as kidney failure and heart disease.
- Conditions
- Diabetic Kidney Disease, Type 2 Diabetes, Chronic Kidney Disease
- Trial name
- RX4DKD (NCT07169422)
- Testing
- Usual care for diabetic kidney disease management without primary care provider., Pharmacist-led validated diabetic kidney disease decision support algorithm.
- Where
- Canada
- Volunteers
- 120 people
- Sponsor
- Nova Scotia Health Authority
Ovarian Cancer
Individualised Versus Conventional Medical Follow-up for Women After Primary Treatment for Ovarian Cancer.
The purpose of this study in women who have completed primary treatment for ovarian cancer is to investigate the effects of individualised follow-up care delivered by a nurse compared to conventional medical follow-up on quality…
- Trial name
- NCT02298855
- Testing
- Individualised follow-up
- Where
- 3 sites in United Kingdom
- Volunteers
- 113 people
- Sponsor
- University College, London
Diabetes Complications, Diabetes Mellitus, Type 2
A Pilot Intervention Study of Health Coaching to Promote Diabetes Self-Care in the Community
Diabetes poses a substantial burden to racial/ethnic minorities and in populations with limited access to healthcare. However, there is a shortage of healthcare providers available to help patients adopt the lifestyle changes…
- Trial name
- C4C (NCT01695278)
- Testing
- Telephone Counseling
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Northwestern University
Postoperative Complications, Complication of Medical Care
Incidence and Outcome of Reintubation in the PACU
This study evaluated the occurrence of reintubation after planned extubation (RAP), the impact of RAP on duration of PACU stay,length of stay,length of postoperative stay,inpatient healthcare costs, unanticipated ICU admission…
- Trial name
- NCT05341596
- Testing
- repeat endotracheal intubation
- Volunteers
- 121,965 people
- Sponsor
- Shangkun Liu (200966)
Pyeloplasty, Complications of Surgical Procedures or Medical Care
Cost-Effectiveness and Clinical Outcomes of Double J Stent Versus Percutaneous Feeding Tube Placement Following Open Pyeloplasty in Pediatric Patients: A Prospective Randomized Single-center Study
Open pyeloplasty is a common surgical intervention for pediatric patients with ureteropelvic junction obstruction. Post-operative management strategies, including the use of a double J stent and a percutaneous feeding tube, vary…
- Conditions
- Pyeloplasty, Complications of Surgical Procedures or Medical Care, Hospital Stay
- Trial name
- DJS (NCT06847841)
- Testing
- Double J Stent Placement, Percutaneous Feeding Tube Placement
- Where
- Pakistan
- Volunteers
- 140 people
- Sponsor
- Hayat Abad Medical Complex, Peshawar