Clinical trials: Comprehension
Gender Identity
TRANSLATE: Transgender and Gender Nonconforming Individuals' Access to Healthcare
Transgender and gender nonconforming (TGNC) individuals face a number of health disparities, many of which can be tied to a lack of access to or use of primary care.
- Trial name
- NCT03808883
- Testing
- TGNC Directed Advocacy Meetings, Facilitated Dialogues between TGNC Cohort and Healthcare Participants
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Case Western Reserve University
Blood Cancer, Bone Marrow Transplant (BMT)
Understanding the Implementation of Cued Exercise Using Wearable Devices and a Custom Smartphone Application Following Bone Marrow Transplant.
The purpose of this study is to pilot test the feasibility of providing patients diagnosed with a hematologic malignancy, undergoing an allogeneic bone marrow transplant, a wearable device and smartphone app (similar to a…
- Trial name
- NCT06645132
- Testing
- exercise intervention
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medical College of Wisconsin
Oxidative Stress
Monitoring Antioxidant/Redox Status at Concordia (MARS-C)
The European Space Agency (ESA) runs a research centre in Antarctica as an earth-based model for long duration deep-space missions.
- Trial name
- MARS-C (NCT04197193)
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Southampton
Lacunar Stroke
The Relationship Between Controlling Risk Factors and Cerebral Haemodynamics in Lacunar Stroke
The goal of this observational study is to look at differences in brain blood flow before and after management of risk factors such as high blood pressure and diabetes in patients with lacunar stroke.
- Trial name
- LACUNAR_CA (NCT06354881)
- Testing
- Transcranial Doppler Ultrasonography (TCD) during sit-stand manoeuvres
- Where
- United Kingdom
- Volunteers
- 75 people
- Sponsor
- University of Leicester
Healthy, Depression
Who Fares Best With Mindfulness Meditation
The overall aim of this observational study is to investigate how individual differences influence the effects of mindfulness meditation to uncover for whom mindfulness is beneficial and for whom it may be harmful.
- Conditions
- Healthy, Depression, Mental Health Issue
- Trial name
- NCT05862636
- Testing
- Mindfulness Training
- Where
- 3 sites in Belgium, United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. dr. Filip Raes
Cancer, Cachexia
Neurobehavioural and Cognitive Changes in Cancer Cachexia (CANCOG)
The goal of this observational study is to to look for changes within the brain, and changes in body-to-brain signals in people with cancer and people who do not have cancer. The main questions it aims to answer are: 1.
- Conditions
- Cancer, Cachexia, Cachexia-Anorexia Syndrome, Appetite Loss
- Trial name
- CANCOG (NCT06112964)
- Testing
- MRI/ Functional MRI, Self-reported questionnaires, Computer based tasks
- Where
- United Kingdom
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Cambridge
Out-of-hospital Cardiac Arrest (OHCA)
Ventilation Performance and Feedback Simulation Trial
The study "Understanding the Effect of Feedback on Ventilation Performance of Rescuers in a Simulation Trial" will address treatments administered by Emergency Medical Services (EMS) during cardiopulmonary resuscitation (CPR) in…
- Trial name
- VENT-SIM (NCT07352709)
- Testing
- Real-time feedback
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Texas Southwestern Medical Center
Schizophrenia, Schizo Affective Disorder
Using Transcranial Magnetic Stimulation (TMS) to Understand Hallucinations in Schizophrenia
This study uses a noninvasive technique called transcranial magnetic stimulation (TMS) to study how hallucinations work in schizophrenia.
- Trial name
- NCT05343598
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 68 people
- Sponsor
- Mclean Hospital
Cervical Cancer Prevention, Cervical Cancer
A Cervical Cancer Prevention Program in Kenya
Cervical cancer is caused by oncogenic, or "high-risk" (HR) human papillomavirus (HPV), and is the main cause of cancer-related death among Kenyan women.
- Trial name
- Merck-3 (NCT06411938)
- Testing
- High Risk HPV DNA Testing, Visual Inspection with acetic acid (VIA) and possible cervical biopsy, Gardisil-9
- Where
- Kenya
- Volunteers
- 2,300 people, healthy volunteers welcome
- Sponsor
- Indiana University
Celiac Disease
A 12-week Exercise Program for Adults With Celiac Disease
Engagement in regular physical activity (PA) is associated with a range of physical and psychological benefits among chronic disease populations.
- Trial name
- MOVE-C (NCT03520244)
- Testing
- Exercise + Holistic Education
- Where
- Canada
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Tuberculosis Infection, Tuberculosis Prevention
Qualitative Understanding of Community TB Services Pre and Post the CHIP-TB Trial
This qualitative study is designed to elicit the perspectives of relevant stakeholders to adapt a community-based TB/HIV intervention aimed on providing home-based TB prevention treatment (TPT) initiation for child TB contacts…
- Trial name
- NCT04494516
- Where
- 2 sites in Ethiopia, South Africa
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Caregiver Interactive Skills
Promoting Sensitivity in Center-based Childcare
The purpose of this study is to test the efficacy of an attachment research-informed intervention adapted to the Danish childcare context in terms of improving process quality in center-based childcare for 0-2 years old children.
- Trial name
- SECURE (NCT04654533)
- Testing
- COSC
- Where
- Denmark
- Volunteers
- 110 people
- Sponsor
- University of Copenhagen
Unspecified Adult Solid Tumor, Protocol Specific
Health Education in Improving the Understanding of Medical Information
RATIONALE: Understanding the risk of disease and prevention and screening activities to lower disease risk may help individuals make informed medical decisions.
- Trial name
- NCT00387998
- Testing
- AHRQ staying healthy booklet, Risk primer
- Volunteers
- 555 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
REM Sleep Behavior Disorder
Understanding the Natural History of REM Sleep Behavior Disorder
The purpose of this research study is to determine if safe, simple and non-invasive tests such as an electrocardiogram (EKG), a smell test, or a blood test could be used to identify neurological disorders before typical symptoms…
- Trial name
- NCT01674998
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The Parkinson's Institute
Drug Abuse/Dependence
Understanding Drug Abuse Treatment Outcomes
Background: Although some treatments for substance abuse are considered effective for some people who are drug dependent, many others do not benefit as much over time.
- Trial name
- NCT01678833
- Where
- 2 sites in United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Diabetes Mellitus, Type 2
A Research Study to Understand How Oral Semaglutide Works in People With Type 2 Diabetes in India
The purpose of the study is to look at the change in blood sugar levels in participants with type 2 diabetes who start using oral semaglutide. Participants will get oral semaglutide as prescribed to them by the study doctor.
- Trial name
- PIONEER REAL (NCT05502562)
- Testing
- Oral semaglutide
- Volunteers
- 388 people
- Sponsor
- Novo Nordisk A/S
This Study Explores How Young Children Aged 3 to 5 Use Interactive Electronic Devices
Observing 3-5 Year Old Children's Use of Interactive Electronic Devices (IED) in the Family Home to Understand the Context These Devices Are Being Used in, Exploring Whether Socioeconomic Factors or Parent's Own Use of Such Devices Influence the Child's IED Usage.
This study aims to explore the context of how children aged 3-5 use interactive electronic devices like tablets or smartphones in their everyday home environment.
- Trial name
- iKids (NCT07373483)
- Where
- United Kingdom
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Sheffield Hallam University
Perinatal Depression
Pilot Study of Mothers and Babies Online in Home Visiting
The investigators propose a pilot randomized controlled trial (RCT) that examines how the redesigned version of Mothers and Babies Online (eMB) can be delivered in the context of home visiting (HV) programs that serve pregnant…
- Trial name
- eMB (NCT05714956)
- Testing
- Mothers and Babies Online (eMB)
- Where
- 6 sites in United States
- Volunteers
- 42 people
- Sponsor
- Northwestern University
Laryngeal Dystonia, Spasmodic Dysphonia
Understanding Disorder-specific Neural Pathophysiology in Laryngeal Dystonia and Voice Tremor
The researchers will examine functional neural correlates that differentiate between laryngeal dystonia and voice tremor and contribute to disorder-specific pathophysiology using a cross-disciplinary approach of multimodal brain…
- Conditions
- Laryngeal Dystonia, Spasmodic Dysphonia, Tremor
- Trial name
- NCT05216770
- Testing
- Brain imaging, Laryngeal sensory block with topical bupivacaine
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Fertility Issues
Home Examinations Researching and Understanding Submucosal Evaluations
To demonstrate that imaging via home ultrasound can identify submucosal fibroids. The image quality and submucosal fibroid detection specificity of the home imaging has already been demonstrated; the aim of this study is to…
- Trial name
- HER-USE (NCT05004870)
- Testing
- Transvaginal ultrasound performed by a woman herself (with HCP supervision via telemedicine)
- Where
- United States
- Sponsor
- Turtle Health, Inc.