Clinical trials: Comprehensive Geriatric Assessment
Colon Cancer Patients Receiving Chemotherapy in the Adjuvant or Metastatic Setting, Aged 70 or Older
MOST: Mediterranean Oncology Senior Tests
MOST is a longitudinal study whose aim is to test the hypothesis that frailty markers are better at detecting vulnerable patients and that they are a better "Adverse Events" predictive tool than the CGA (Comprehensive Geriatric…
- Trial name
- MOST (NCT02148731)
- Testing
- Frailty markers
- Where
- 8 sites in France
- Volunteers
- 180 people
- Sponsor
- Association Sud pour la Recherche en Oncogériatrie
Bladder Cancer
Comprehensive Geriatric Assessment for Perioperative Optimization in Cystectomy
Patients with muscle-invasive bladder cancer are often older and multimorbid, thus in an increased risk of perioperative mortality and morbidity in relation to radical cystectomy (RC).
- Trial name
- COMPETENCE (NCT05679557)
- Testing
- Perioperative geriatric assessment and intervention
- Where
- Denmark
- Volunteers
- 140 people
- Sponsor
- Aarhus University Hospital
Frailty
Comprehensive Geriatric Assessment in Primary Care: A Randomised Feasibility Trial
The study aims to explore feasibility of implementing a tailored CGA to older adults with frailty and evaluate staff and patients perception of the intervention. In line with this, the objectives of the study are: 1.
- Trial name
- NCT03394534
- Testing
- CGA group
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University of Derby
Accidental Falls
Effect on Falls Reduction of a Multimodal Intervention in Frail and Pre-frail Elderly Community-dwelling People
Practice guidelines in caring for the geriatric population recommend performing an annual screening of falls . However, one of the problems that interfere with fall prevention programs is the lack of importance accorded to health…
- Trial name
- FAREMAVA (NCT02631330)
- Testing
- Multicomponent physical activity
- Where
- Spain
- Volunteers
- 466 people, healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Elderly Inpatients, Frail
Prevalence and Influencing Factors of Frailty in Elderly Patients With Heart Failure
The goal of this observational study is to investigate the prevalence and associated factors of frailty in hospitalized elderly patients with heart failure.
- Conditions
- Elderly Inpatients, Frail, Heart Failure Hospitalization, CGA
- Trial name
- NCT07510035
- Where
- China
- Volunteers
- 298 people
- Sponsor
- Zhejiang Hospital
Tumor, Health Services Research
Care Pathways and Disparities in Care for Older Patients With Cancer: Typology, Determinants and Effect on Prognosis ( PASSAGE )
More than half of new cases of cancer in Europe in 2022 occurred in people aged over 70. In addition to cancer, the majority of older people have one or more illnesses that may interact with the treatment decision, cancer…
- Conditions
- Tumor, Health Services Research, Causality, Geriatric Assessment
- Trial name
- PASSAGE (NCT07092800)
- Where
- France
- Volunteers
- 75,000 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Frailty, Geriatric Syndromes
Beneficial Effects of an Integrated Program of Multicomponent Physical Exercise. Cohort Study
The study has been designed to analyze the possible positive effects of a multicomponent physical exercise program monitored with an integrated electronic device system in dwelling-community frailty older adults.
- Conditions
- Frailty, Geriatric Syndromes, Functional Recovery
- Trial name
- Ros-Ita (NCT04711785)
- Testing
- Multicomponent exercise program
- Where
- Spain
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hospital de la Ribera
Hematologic Malignancy
Composite Health Assessment Risk Model (CHARM) for Older Adults (BMT CTN 1704)
Prospective observational multicenter study of allogeneic Hematopoietic Stem Cell Transplantation (HCT) in recipients 60 years and older to assess important determinants of health status to be combined into a composite health…
- Trial name
- BMT CTN 1704 (NCT03992352)
- Testing
- Age 60+ with planned HCT for Hematologic Malignancy
- Where
- 50 sites in United States
- Volunteers
- 1,229 people
- Sponsor
- Center for International Blood and Marrow Transplant Research
B-Cell Non-Hodgkin Lymphoma, Multiple Myeloma
Geriatric Assessment Guided Interventions to Accelerate Functional Recovery After CAR-T Therapy for Patients 60 Years and Older With B-cell Non-Hodgkin Lymphoma or Multiple Myeloma, GOCART Study
This clinical trial compares the effectiveness of geriatric assessment (GA) guided interventions to accelerate functional recovery after chimeric antigen receptor T-cell (CAR-T) therapy compared to standard of care (SOC) in…
- Trial name
- NCT06052826
- Testing
- Best Practice, Cognitive Intervention, Comprehensive Geriatric Assessment
- Where
- 4 sites in United States
- Volunteers
- 164 people
- Sponsor
- City of Hope Medical Center
Geriatric Assessment, Geriatric Oncology
Geriatric Oncology Care in Brazil: Remote Geriatric Assessment-Driven Interventions With Supportive Care
The goal of this clinical trial is to determine whether a telehealth-delivered, geriatric assessment-guided supportive care program (GAIN-S) can improve health outcomes in older adults (age 65 and above) with solid tumors who are…
- Conditions
- Geriatric Assessment, Geriatric Oncology, Quality of Life, Functional Decline
- Trial name
- GAIN-S (NCT07084454)
- Testing
- GAIN-S Multidisciplinary Telehealth Intervention, Standard Oncology Care
- Where
- Brazil
- Volunteers
- 350 people
- Sponsor
- Cristiane Decat Bergerot, PhD
Veterans, Geriatric Assessment
Inter-Disciplinary Outpatient Care Model Providing Comprehensive Geriatric Assessment, Care-Coordination & Co-management
The Department of Veterans Affairs' (VA) Home Based Primary Care (HBPC) program provides comprehensive care to its sickest, frailest Veterans with multiple complex chronic diseases.
- Conditions
- Veterans, Geriatric Assessment, Care-Coordination, Outpatient Care
- Trial name
- C4 (NCT04846049)
- Testing
- Comprehensive Care, Standard Care
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Miami VA Healthcare System
Cancer, Geriatric Assessment
Falls Risk Questionnaire in Older Adults With Cancer
The purpose of this research study is to look at the use of a series of questionnaires evaluating risk for falls in order to collect information that might be used to develop a larger study aiming to recognize who is more at risk…
- Trial name
- NCT02204137
- Testing
- Falls Risk Questionnaire, Cancer and Aging Research Group Geriatric Assessment, Falls Efficacy Scale-International (FES-1)
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Washington University School of Medicine
Colorectal Cancer, Oncologic Complications
The SaVe Project-Sarcopenia and Vertigo in Aging Patients With Colorectal Cancer
The goal of this clinical trial is to learn about the cause of dizziness and decline in walking ability in in older adults ≥65 years during chemotherapy treatment for colorectal cancer.
- Conditions
- Colorectal Cancer, Oncologic Complications, Comprehensive Geriatric Assessment, Vestibular Rehabilitation
- Trial name
- SaVe (NCT05710809)
- Testing
- Targeted specialized physical group-based exercise and Comprehensive Geriatric Assessement
- Where
- 2 sites in Denmark
- Volunteers
- 150 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Cancer, Frailty
G8 Screening Tool Validation in Older Adults With Cancer in Portugal
The G8 screening tool is widely recommended for the identification of frailty in older adults with cancer. However, prospective validation data in the Portuguese population are currently lacking.
- Conditions
- Cancer, Frailty, Aged
- Trial name
- G8-PT (NCT07487298)
- Testing
- G8 Screening Tool, Comprehensive Geriatric Assessment
- Where
- Portugal
- Volunteers
- 150 people
- Sponsor
- Hospital de Braga
Frailty
Comprehensive Geriatric Assessment in the Emergency Department
Comprehensive geriatric assessment (CGA) has been shown to improve outcomes in an inpatient setting; however, there is currently no compelling evidence of benefit for CGA interventions within the Emergency Department (ED).
- Trial name
- NCT05252182
- Where
- Ireland
- Volunteers
- 133 people
- Sponsor
- University of Limerick
Geriatric Disorder
(MIGA) Mini Geriatric Assessment To Replace the Comprehensive Geriatric Assessment
This is a comprehensive Geriatric Assessment (CGA) currently used to evaluate elderly people in order to be able to assess their multiple organ pathology, cognitive, functional and social problems.
- Trial name
- MIGA (NCT01318759)
- Where
- Israel
- Volunteers
- 400 people
- Sponsor
- Tel-Aviv Sourasky Medical Center
Acute Myeloid Leukemia
Integrating Geriatric Assessment for Older Patients Diagnosed With Acute Myelogenous Leukemia
Despite the suggestions that GA and frailty indices could be used to guide therapy selection, the ability to effectively incorporate the use of GA in older patients diagnosed with AML in a real-world clinic environment has not…
- Trial name
- NCT04158726
- Testing
- modified Geriatric Assessment (mGA)
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Carevive Systems, Inc.
Hematopoietic and Lymphatic System Neoplasm, Malignant Solid Neoplasm
Understanding Needs of Older Patients Prior to Starting Cancer Treatment
A geriatric assessment (GA) is a structured approach to identifying and addressing the strengths and vulnerabilities of older adults with cancer.
- Trial name
- PGA (NCT07225920)
- Testing
- Survey Administration, Interview, Educational Intervention
- Where
- 42 sites in United States, Puerto Rico
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Diffuse Large B Cell Non-Hodgkin Lymphoma
A Combination of Rituximab and CC-99282 as Front-line Therapy for Older Frail Patients With Diffuse Large B-cells Non-Hodgkin Lymphoma Evaluated With a Simplified Geriatric Assessment (sGA): a Phase II Study of the Fondazione Italiana Linfomi (FIL)
Prospective, multicenter, single arm, phase II study, to evaluate the efficacy of the combination rituximab-golcadomide as a chemo free approach in a population of older patients with new diagnosis of DLBCL, defined as frail…
- Trial name
- FIL_RICCO (NCT06835530)
- Testing
- Rituximab + Golcadomide (CC-99282)
- Where
- 20 sites in Italy
- Volunteers
- 47 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Exercise, Gait
Rhythmically Entrained Exercise in Community-Dwelling Older Adults
Researchers at the University of North Carolina at Greensboro conduct a single-arm intervention trial to investigate the efficacy of a music-based group exercise program for community-dwelling older adults.
- Conditions
- Exercise, Gait, Cognitive Decline, Caregiver Burden
- Trial name
- REECO (NCT05462977)
- Testing
- Group exercise program
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Greensboro