Clinical trials: Comprehensive Geriatric Assessment
Hematological Cancers, Frailty
Improving Quality of Life in Frail, Older Patients with Hematological Cancer Through Geriatric Assessment and Treatment - a Pilot Study
Purpose of the Study This study aims to assess the feasibility of conducting outpatient geriatric health assessment (comprehensive geriatric assessment - CGA) alongside initiation of hematological cancer treatment in frail older…
- Conditions
- Hematological Cancers, Frailty, ELDERLY PEOPLE
- Trial name
- IMPROVE pilot (NCT06689332)
- Testing
- Comprehensive Geriatric Assessment
- Where
- Denmark
- Volunteers
- 17 people
- Sponsor
- Odense University Hospital
Healthy Volunteers
Screening for Frailty at Home
"Many tools to evaluate frailty have been developed. However, at the time our study was designed, none of these instruments had been validated in terms of psychometric properties.
- Trial name
- SEGAm (NCT02852200)
- Testing
- SEGAm
- Where
- France
- Volunteers
- 167 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Multimorbidity, Knee Arthrosis
Interprofessional Preoperative Geriatric Assessment for Older Arthroplasty Patients With Multimorbidity
The objective of this randomized control trial is to investigate effects and cost effectiveness of interprofessional preoperative assessment among older knee or hip arthroplasty patients.
- Conditions
- Multimorbidity, Knee Arthrosis, Hip Arthrosis
- Trial name
- IPPGA-RCT (NCT04001699)
- Testing
- Preoperative geriatric assessment
- Where
- Finland
- Volunteers
- 157 people
- Sponsor
- University of Eastern Finland
Chronic Diseases in Older Adults, Malnutrition
Elderly Health Profile in a Rural Village of Assiut
This study aims to assess the health, nutrition, functional status, and quality of life of older adults living in Al-Boura village in Assiut, Egypt.
- Conditions
- Chronic Diseases in Older Adults, Malnutrition, Frailty, Functional Decline Geriatric Health
- Trial name
- RURAL-AGE (NCT07263087)
- Where
- Egypt
- Volunteers
- 330 people
- Sponsor
- Assiut University
Colo-rectal Cancer
NURSE-led Geriatric Assessment in Older Colorectal Cancer Patients
Older colorectal cancer patients frequently present with frailty, comorbidity, and other age-related vulnerabilities that may affect treatment tolerance and outcomes.
- Trial name
- NURSE-GA (NCT07872787)
- Testing
- Nurse-led Geriatric Assessment
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- Helse Stavanger HF
Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia
Geriatric Assessment & Genetic Profiling to Personalize Therapy in Older Adults With Acute Myeloid Leukemia
Acute myeloid leukemia (AML) is among the most common hematologic malignancies in adults and accounts for approximately 10,000 deaths in the United States every year. AML is commonly diagnosed in sixth or seventh decades of life.
- Conditions
- Adult Acute Myeloid Leukemia, Secondary Acute Myeloid Leukemia, Therapy-Related Acute Myeloid Leukemia
- Trial name
- NCT03226418
- Testing
- Cytarabine, Decitabine, Idarubicin
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- University of Nebraska
Aging, Inpatients
Epidemiological Observatory on the Health Conditions of Inpatients Aged 65 or Older at the INRCA Research Hospitals
The goal of this research study is to collect clinical data, comprehensive geriatric assessment, risk factors, biological data and blood samples from inpatients aged 65 and older at the INRCA research hospitals (Italy).
- Trial name
- report-AGE (NCT01397682)
- Testing
- blood sample collection
- Where
- 4 sites in Italy
- Volunteers
- 2,250 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Delirium
Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR)
This is a pilot randomized controlled trial that will test whether a multicomponent decision support system will improve the postoperative environment for neurocognitive and clinical recovery in older, high-risk surgical…
- Trial name
- NCT04007523
- Testing
- Family Support System, HELP Support System
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Michigan
Frailty, Frailty Syndrome
Frailty Screening in the Swedish Emergency Department Setting
This prospective observational study will investigate the correlation of frailty in relation to serious outcomes. Serious outcomes are defined as: mortality within 30 days, admission to hospital, length of stay in the Emergency…
- Conditions
- Frailty, Frailty Syndrome, Emergency Department, Geriatric Assessment
- Trial name
- NCT04877028
- Where
- Sweden
- Volunteers
- 1,800 people
- Sponsor
- University Hospital, Linkoeping
Frailty
Feasibility and Acceptability of the Clinical Frailty Scale in a Swedish Emergency Department Setting
The purpose of this study is to evaluate the feasibility and acceptability of the Clinical Frailty Scale (CFS). The scale can potentially be adopted for daily use in the Emergency Department (ED) and have been evaluated with…
- Trial name
- NCT04931472
- Where
- Sweden
- Volunteers
- 229 people
- Sponsor
- University Hospital, Linkoeping
Frail Elderly Syndrome
Frailty and Complexity Among Home Service Recipients
The purpose of the study is to develop frailty and complexity computation algorithms based on the French version of the interRAI-HC and, in doing so, to provide homecare nurses with valid and reliable screening tools for their…
- Trial name
- fraXity (NCT03883425)
- Testing
- interRAI-HC assessments
- Where
- Switzerland
- Volunteers
- 231 people
- Sponsor
- School of Health Sciences Geneva
Colon Cancer, Frailty
Optimised Post-discharge Care in Older Patients After Surgery for Colon Cancer (ERAS 3.0)
The purpose of the study is to investigate whether an extended program (ERAS 3.0) initiated hospital discharge, can improve recovery in elderly, frail patients who have undergone surgery for colon cancer.
- Trial name
- NCT06802991
- Testing
- ERAS 3.0 (Enhanced Recovery After Surgery)
- Where
- 2 sites in Denmark
- Volunteers
- 60 people
- Sponsor
- Copenhagen University Hospital at Herlev
Geriatric Assessment, Muscle Strength
Effects of a Program of Physical Exercise and Electrotherapy on Muscle Strength in Subjects of the Fourth Age
The purpose of this study is to determine whether neuromuscular electrical stimulation, strengthening exercises, or combination of both over lower limbs are effective in the improvement of the stability fundamentally against…
- Conditions
- Geriatric Assessment, Muscle Strength, Postural Balance, Body Mass Index
- Trial name
- NCT01086592
- Testing
- No intervention, Strong progressive strengthening exercises of lower limbs, Electrotherapy
- Where
- Spain
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- Cardenal Herrera University
Solid Cancers, Geriatric Assessment
Application of the sG8 Scale in Real-World Geriatric Oncology Patients
This study is a multicenter, prospective, observational study. The study included patients aged 65 and older with solid tumors requiring systemic anti-tumor therapy.
- Trial name
- NCT06939764
- Testing
- Geriatric Screening using the sG8 scale
- Volunteers
- 346 people
- Sponsor
- Sichuan Cancer Hospital and Research Institute
Pancreatic Cancer, Surgery
Quality of Life in Elderly Patients After Pancreatic Cancer Surgery
Pancreatic cancer mainly affects the elderly, with over 85% of patients diagnosed after the age of 60 and over half after the age of 70.
- Conditions
- Pancreatic Cancer, Surgery, Elderly
- Trial name
- ADL_DPC_PA (NCT06079229)
- Testing
- Phone call
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hospices Civils de Lyon
Breast Neoplasms, HER2/Neu Positive
Tolerability of the Combination of Lapatinib and Trastuzumab in Adults Age 60 or Older With HER2 Positive Locally Advanced or Metastatic Breast Cancer
This phase II trial studies the side effects and how well lapatinib ditosylate and trastuzumab work in treating older patients with human epidermal growth factor receptor 2 (HER2)-positive breast cancer that has spread from where…
- Conditions
- Breast Neoplasms, HER2/Neu Positive, Geriatric Health Services
- Trial name
- NCT01273610
- Testing
- Lapatinib, Trastuzumab, laboratory biomarker analysis
- Where
- 8 sites in United States
- Volunteers
- 40 people
- Sponsor
- City of Hope Medical Center
Acute Myeloid Leukemia (AML)
Improving Delivery of Aging-Related Supportive Care for Older Adults With Acute Myeloid Leukemia
The goal of this clinical trial is to test a way of delivering supportive care to adults 60 years and older who are starting venetoclax-based treatment for newly diagnosed acute myeloid leukemia (AML).
- Trial name
- ACTIVE DEFAULT (NCT07777471)
- Testing
- Active Default
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Colorectal Cancer, Fatigue
Physical Activity Intervention for Older Patients During Chemotherapy for Colorectal Cancer
This study will see if patient who undergo a physical activity intervention called Walk With Ease report experiencing less fatigue and a higher quality of life during chemotherapy for colorectal cancer than those who do not…
- Trial name
- NCT02191969
- Testing
- Walk With Ease
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Ovarian Cancer, Peritoneal Cancer
Geriatric Assessment and Nursing Telephone Intervention in Elderly Women With Ovarian Cancer
Older woman with ovarian cancer have a worse prognosis compared to younger patients. However, the reason is not known. Currently, the standard of care is to evaluate younger and older patients with cancer the same way.
- Conditions
- Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
- Trial name
- NCT01471483
- Testing
- geriatric assessment and telephone call from nurse, geriatric assessment and no call from nurse
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Solid Carcinoma, Frailty
Geriatric Oncology Screening of Older Patients With Solid Cancers
Older patients with cancer constitute a heterogeneous group with varying comorbidity; therefore, geriatric assessment with initial screening is recommended. The Geriatric 8 (G8) has been established as a promising screening tool.
- Conditions
- Solid Carcinoma, Frailty, Age, Geriatrics
- Trial name
- PROGNOSIS-G8 (NCT04644874)
- Testing
- Geriatric 8, modified Geriatric 8, 30 second chair stand test
- Where
- Denmark
- Volunteers
- 1,401 people
- Sponsor
- Odense University Hospital