Clinical trials: Compression Fracture
Vertebral Compression Fractures, Pathological Fracture
Prospective Evaluation of Therapeutic Combination in Treating Vertebral Compression Fractures
The purpose of this study is to collect clinical and radiographic outcomes in patients undergoing vertebroplasty procedures for the treatment of osteoporotic or pathological fractures of the vertebral body to understand the role…
- Conditions
- Vertebral Compression Fractures, Pathological Fracture, Facet Joint Arthropathy
- Trial name
- PROTECT (NCT06670404)
- Testing
- Vertebroplasty
- Where
- Switzerland
- Volunteers
- 130 people
- Sponsor
- Prof Nicolas Theumann
Osteoporosis, Fractures, Compression
Dynamic Magnetic Resonance (MR) Study in Evaluating the Vertebral Bone Marrow Perfusion and Its Related Research
The etiology and pathogenesis of osteoporosis has been extensively discussed. The relationship between bone blood circulation and the formation of bony trabeculae has been less understood.
- Trial name
- NCT00172224
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Vertebral Compression Fracture
Investigating Bone Cement With or Without Inossia® Cement Softener for Vertebral Compression Fractures
The overall purpose of conducting this study is to evaluate the safety and efficacy of V-Flex and V-Steady for augmentation of osteoporotic vertebral compression fractures and to verify that adding a cement softener into a PMMA…
- Trial name
- SOFTBONE (NCT05676320)
- Testing
- V-Flex, V-Steady
- Where
- 9 sites in Canada, Germany and 2 more
- Volunteers
- 203 people
- Sponsor
- Inossia AB
Posture, Vertebral Compression Fracture
The Spine Kinematics and Center of Pressure Excursion During Functional Task Vertebral Compression Fractures Subjects
This study aimed to assess the sensory and kinematic components of the limits of stability (LOS) test in patients with vertebral compression fracture (VCF) .
- Trial name
- NCT04135755
- Testing
- no drug intervention
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
LC Pelvic Fracture
Pelvis RCT: Impact of Surgery on Pain in Lateral Compression Type Pelvic Fractures
Lateral compression type pelvic ring injuries remain the most common type of pelvic fractures encountered. There is a substantial amount of controversy surrounding the treatment of these injuries and there is evidence that both…
- Trial name
- NCT02625766
- Testing
- LC fracture surgical fixation, LC fracture non-operative management
- Where
- 2 sites in United States
- Volunteers
- 95 people
- Sponsor
- University of Maryland, Baltimore
Anterior Mandibular Fracture
Evaluation of Condylar Position After Anterior Mandibular Fracture Fixation Using Plates Versus Headless Compression Screws
This study compares two methods for fixing fractures of the front part of the lower jaw: Conventional plates and screws Headless compression screws Patients are randomly assigned to one of the two treatment groups.
- Trial name
- fracture (NCT07826403)
- Testing
- headless compression screw, conventional plates
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Acute Lymphoblastic Leukemia, Nephrotic Syndrome
Steroid-Induced Osteoporosis in the Pediatric Population - Canadian Incidence Study
To determine the magnitude and rate of bone mass deficits following initiation of glucocorticoid therapy for the treatment of pediatric leukemia, rheumatic conditions and nephrotic syndrome, we propose a 6 year, prospective study…
- Conditions
- Acute Lymphoblastic Leukemia, Nephrotic Syndrome, Rheumatism
- Trial name
- STOPP-CIS (NCT01663129)
- Where
- 12 sites in Canada
- Volunteers
- 406 people
- Sponsor
- Children's Hospital of Eastern Ontario
Osteoporotic Vertebral Compression Fracture
The Comparative Study About the Effect of Vertebral Body Decompression Procedure
The purpose of this study is to compare the treatment efficacy between vertebral body decompression procedure and conservative treatment with non-inferiority design
- Trial name
- NCT02902250
- Testing
- Decompression, Conservative Treatment
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Seoul National University Hospital
Osteoporotic Vertebral Compression Fracture
Unilateral Versus Bilateral Vertebroplasty in Local Anaesthesia
Osteoporotic vertebral compression fractures are a common cause of severe back pain and disability in elderly patients. Percutaneous vertebroplasty (PVP) with polymethylmethacrylate (PMMA) cement is widely used to relieve pain…
- Trial name
- UNI-BI PVP (NCT07198776)
- Testing
- Percutaneous Vertebroplasty
- Where
- Slovenia
- Volunteers
- 196 people
- Sponsor
- Igor Movrin
Osteoporosis
Percutaneous Vertebroplasty Versus Conservative Treatment in GIOPVCF
Based on the case reports and other literature, the investigators hypothesize that using PVP for treating GIOPVCF is associated with increased risk of vertebral refractures and does not provide further benefits compared to…
- Trial name
- NCT03330340
- Testing
- Percutaneous Vertebroplasty
- Volunteers
- 106 people
- Sponsor
- Peking University First Hospital
Bone Metastases
A Study Comparing Denosumab vs. Zoledronic Acid for the Treatment of Bone Metastases in Breast Cancer Subjects.
The purpose of this study is to determine if denosumab is non-inferior to zoledronic acid in the treatment of bone metastases in subjects with advanced breast cancer.
- Trial name
- NCT00321464
- Testing
- Denosumab, Zoledronic Acid
- Volunteers
- 2,049 people
- Sponsor
- Amgen
Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures
A Controlled Trial of Vertebroplasty for Acute Painful Osteoporotic Fractures
The objective of this study is to gather data regarding the efficacy, safety and cost-effectiveness of percutaneous vertebroplasty in the acute fracture group with fractures less than 6 weeks old.
- Conditions
- Vertebral Compression Fractures, Osteoporotic Vertebral Compression Fractures, Acute Vertebral Fractures
- Trial name
- NCT01482793
- Testing
- Vertebroplasty
- Where
- Australia
- Volunteers
- 120 people
- Sponsor
- Optimus Clinical Research
Femur Fractures
Types of Fixation of Vancouver B1 Periprosthetic Fractures
The purpose of this study is to compare two different but standard treatments for the fixation of Vancouver B1 periprosthetic. The investigators aim to compare open reduction internal fixation using a locked plating system versus…
- Trial name
- NCT01354535
- Testing
- Isolated Locked Compression Plate, Cable Plating and Strut Allograft with Cerclage Wiring
- Where
- Canada
- Volunteers
- 89 people
- Sponsor
- Unity Health Toronto
Osteoporotic Vertebral Fracture, Between T5 and L5
Comparison of Balloon Kyphoplasty and Vertebroplasty in Subacute Osteoporotic Vertebral Fractures
This study aims to compare two treatments in subacute (more than 6 week duration) non-traumatic (usually osteoporotic) vertebral fractures. The two treatments are the following: 1.
- Conditions
- Osteoporotic Vertebral Fracture, Between T5 and L5, Chronic Arthritis, Longer Than Six Weeks Duration
- Trial name
- OSTEO+6 (NCT00749086)
- Testing
- balloon kyphoplasty, vertebroplasty
- Where
- France
- Volunteers
- 97 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Vertebral Compression Fracture, Osteoporotic Fractures
Efficacy of WJ-derived Mesenchymal Stem Cells in Combination With Parathyroid Hormone for Vertebral Compression Fracture
Osteoporotic vertebral compression fractures (OVCFs) are serious health problems. Transplantation of mesenchymal stem cells (MSCs) has gained considerable attention to treat osteoporosis and OVCFs because implanted healthy MSCs…
- Trial name
- NCT05018637
- Testing
- WJ-MSC, Teriparatide
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Inbo Han
Femoral Neck Fractures
Comparison of Clinical Efficacy Between Dynamic Dip Screw and Cannulated Compression Screw for Fresh Femoral Neck Fracture
For fresh femoral neck fracture internal fixation, both DHS and CCS can make strong fixation of hip and have good recovery. There is no statistical difference in complications after surgery between the two procedures.
- Trial name
- NCT04959370
- Testing
- internal fixation implantation of dynamic hip screw, internal fixation implantation of cannulated compression screw
- Where
- China
- Volunteers
- 91 people
- Sponsor
- Peking University Third Hospital
Compression Fracture
Comparison of Treatments of Osteoporotic Compression Fracture Using Rigid Brace, Soft Brace, and no Brace
The treatment outcomes in the treatment without brace would be non-inferior to those in use of rigid or soft brace.
- Trial name
- NCT02049931
- Testing
- No brace treatment, Rigid brace, Soft brace
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Osteoporosis, Compression Fracture
Vertebroplasty Using Real-Time, Fluoroscopy-Controlled, Catheter-Assisted, Low-Viscosity Cement Injection
Th low viscosity cement injection is safe in vertebroplasty procedure with Comparacle out come in pain relief.
- Trial name
- NCT00689923
- Volunteers
- 100 people
- Sponsor
- National Taiwan University Hospital
Vertebral Compression Fracture
Performance and Safety of Joline® Kyphoplasty Single Balloon Catheter Allevo vs. Quattroplasty Double-Balloon Catheter Stop'n GO With BonOs® Inject Bone Cement
The purpose of this study is to assess the performance and safety of two balloon kyphoplasty systems (Joline®), the single balloon catheter Allevo and Quattroplasty double balloon catheter Stop'n Go, using BonOs® Inject bone…
- Trial name
- NCT04581707
- Testing
- Kyphoplasty Single Balloon Catheter Allevo, Quattroplasty Double Balloon Catheter Stop'n GO
- Where
- Germany
- Volunteers
- 80 people
- Sponsor
- University Hospital Tuebingen
Sternal Fracture, Sternal Wound Infection
Sternal Wound Infection in Patients Undergone Sternal Fixation Using Locking Compression Plates
Sternal Wound Infection (SWI) in open heart surgery is one of the most annoying and avoidable complications that one encounters during work.
- Conditions
- Sternal Fracture, Sternal Wound Infection, Surgical Site Infection
- Trial name
- NCT05040399
- Testing
- Locking Compression Plates, Sternal Wires
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Assiut University