Clinical trials: Compression Fracture
Vertebral Compression Fracture
A Clinical Study Evaluating the Safety and Efficacy of the VCFix Spinal System for Treatment of Vertebral Compression Fractures
This study is being conducted to evaluate the safety and performance of the VCFix Spinal System, a medical device designed to treat certain types of spinal fractures called vertebral compression fractures (VCFs) in adults.
- Trial name
- EXPAND (NCT07301749)
- Testing
- VCFix Spinal System in stand-alone configuration
- Where
- 3 sites in France, Germany
- Volunteers
- 148 people
- Sponsor
- Amber Implants B.V.
Osteoporosis Fracture, Osteoporosis Vertebral
Development and Validation of a Postoperative Re-fracture Risk Model for Osteoporotic Spinal Fractures
In this project, IDEAL-IQ technology and PDFF and R2* image-based imaging methods are used to analyze the intrinsic relationship between preoperative vertebral bone marrow fat content, magnetic susceptibility properties of bone…
- Conditions
- Osteoporosis Fracture, Osteoporosis Vertebral, Compression Fracture, Perform PVP / PKP Treatment
- Trial name
- NCT06379243
- Testing
- PVP/PKP
- Where
- China
- Volunteers
- 560 people
- Sponsor
- The Seventh Affiliated Hospital of Sun Yat-sen University
Osteoporotic Vertebral Compression Fractures, Lung Function
Osteoporotic Vertebral Compression Fractures: Can Kyphoplasty Improve Lung Function? A Prospective Evaluation
Patients with vertebral fractures often have problems to straighten and as a consequence of impaired lung ventilation that leads to a impaired lung function.
- Trial name
- NCT01609712
- Testing
- Radiofrequency Kyphoplasty
- Where
- Germany
- Volunteers
- 30 people
- Sponsor
- University Hospital, Bonn
Vertebral Compression Fracture, Korean Traditional Medicine
Long Term Follow-up of Vertebral Compression Fracture In-patients Treated: A Retrospective Chart Review and Survey
The purpose of this study is to reveal the effectiveness and safety of integrative Korean medicine for Vertebral Compression Fracture in-patients by observing inpatients treated with integrative Korean medicine.
- Conditions
- Vertebral Compression Fracture, Korean Traditional Medicine, Integrative Korean Medicine, Vertebral Compression
- Trial name
- NCT05912504
- Testing
- Phoen survey
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Jaseng Medical Foundation
Osteoporotic Vertebral Compression Fractures
CT-Based Deep Learning for Differentiating Acute and Chronic Osteoporotic Vertebral Compression Fractures
Osteoporotic vertebral compression fractures are common in older adults and may present as either acute or chronic fractures. Correctly distinguishing acute from chronic fractures is clinically important because treatment…
- Trial name
- CT-DL-OVCF (NCT07306858)
- Testing
- No Intervention (Observational Study)
- Where
- China
- Volunteers
- 276 people
- Sponsor
- Xin Fan
Denosumab Allergy
Denosumab and Screw Fixation for Osteoporotic Compression Fracture
Evaluation of bone mineral density and function at 1 year after screw internal fixation of osteoporotic vertebral compression fractures with desuzumab: a parallel double-blind randomized controlled clinical trial
- Trial name
- NCT05065164
- Testing
- Denosumab Only Product
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Shenzhen People's Hospital
Vertebral Compression Fracture, Spinal Trauma
VertebrOpLasty Versus Conservative Treatment in Acute Non Osteoporotic Vertebral Fractures
The purpose of this protocol is to prove the efficacy of vertebroplasty in patients suffering from acute non osteoporotic vertebral compression fracture.
- Trial name
- VOLCANO (NCT01643395)
- Testing
- vertebroplasty, conservative therapy
- Where
- France
- Volunteers
- 99 people
- Sponsor
- University Hospital, Clermont-Ferrand
Edema
Effective Treatment of Posttraumatic and Postoperative Edema
Edema control after ankle- and hindfoot fractures is important. Multi-layer compression bandages or A-V Impulse compression may are more effective in reducing edema than ice.
- Trial name
- NCT01389089
- Testing
- ice gel pack, Multi-layer compression bandage, A-V Impulse compression
- Where
- Switzerland
- Volunteers
- 64 people
- Sponsor
- Luzerner Kantonsspital
Vertebral Body Compression Fracture(s)
Biological Allograft Chain Tissue Implant
A prospective, multi-center study evaluating allograft tissue as a bone void filler when implanted with Lenoss Medical manual surgical instrumentation in patients with painful vertebral compression fractures.
- Trial name
- NCT04064710
- Testing
- Vertebral Body Augmentation, Manual Surgical Instruments
- Where
- 5 sites in United States
- Volunteers
- 26 people
- Sponsor
- Lenoss Medical
Sickle Cell Disease, Sickle Cell Anemia
Sickle Cell Disease (SCD) Bone Pain Study
A prospective study to determine how low bone mineral density and/or vertebral compression fractures associate with pain in adults with sickle cell disease
- Conditions
- Sickle Cell Disease, Sickle Cell Anemia, Low Bone Density, Osteoporosis
- Trial name
- NCT05283148
- Testing
- Dual-energy X-ray absorptiometry, Vertebral fracture analysis, Adult Sickle Cell Quality of Life Measurement System pain impact questionnaire
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of California, Davis
Spinal Fractures, Vertebral Compression Fractures
SpineJack® Versus Conservative Treatment Study (SPICO Study)
This study will compare two standard treatments in acute stable traumatic vertebral fractures (types A1 and A3.1 by Magerl Classification). The two treatments are as follows: 1. SpineJack® system 2.
- Conditions
- Spinal Fractures, Vertebral Compression Fractures, Back Injuries, Trauma
- Trial name
- NCT02657265
- Testing
- SpineJack system, Conservative management
- Where
- 9 sites in France
- Volunteers
- 100 people
- Sponsor
- Vexim SA
Osteoporosis Fracture
The Construction of Bidirectional Column Study of Acute Osteoporotic Vertebral Compression Fractures
Our research group plans to establish a disease specific bidirectional cohort study on prognosis prediction of acute osteoporotic vertebral compression fracture based on imaging and clinical data, and to establish a comprehensive…
- Trial name
- NCT06586996
- Testing
- no intervention
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Peking University Third Hospital
Lateral Compression 1 Pelvic Fracture
Geriatric Lateral Compression 1 Pelvic Fractures
Lateral compression-1 (LC1) pelvic ring fragility fractures cause significant pain and morbidity. These fragility injuries are associated with prolonged immobility and long hospital stays.
- Trial name
- NCT05765669
- Testing
- Percutaneous screw fixation, Pain management, Physical therapy
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- HealthPartners Institute
Vertebral Fracture, Kyphoplasty
Porous Titanium Microspheres in Kyphoplasty
Study is a prospective observational, performed in the context of normal clinical practice, of patients with osteoporotic vertebral compression fractures identified as candidates for kyphoplasty treatment with porous trabecular…
- Trial name
- NCT05815251
- Where
- Italy
- Volunteers
- 15 people
- Sponsor
- Unit of neurosurgery, Departement of Neurosciences, University of Torino
Osteoporotic Vertebral Compression Fractures
Tripod-Fix Vertebral Body Augmentation System in Osteoporotic Vertebral Compression Fractures Treatment
This study is to evaluate the safety and effectiveness of the Tripod-Fix with Tecres Mendec® Spine HV System to treat subjects with osteoporotic vertebral compression fractures.
- Trial name
- NCT06261242
- Testing
- Tripod-Fix Vertebral Body Augmentation System (Tripod-Fix)
- Where
- Taiwan
- Volunteers
- 12 people
- Sponsor
- National Cheng-Kung University Hospital
Vertebral Fracture, Multiple Myeloma
Treatment of Malignant Vertebral Fractures With Percutaneous Balloon Kyphoplasty.
Balloon Kyphoplasty is an alternative to vertebroplasty in the treatment of painful malignant vertebral fractures. This is a mini-invasive percutaneous treatment, aiming to stabilize the vertebral fracture, decrease of pain.
- Conditions
- Vertebral Fracture, Multiple Myeloma, Osteolytic Metastases
- Trial name
- KYPHOK (NCT00748631)
- Testing
- balloon kyphoplasty
- Where
- 4 sites in France
- Volunteers
- 60 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Painful Osteoporotic Vertebral Compression Fractures (VCF)
The PRIORi-T Trial--Prospective Randomized Investigation of Radiofrequency Targeted Vertebral Augmentation
The objective of this post market clinical investigation is to evaluate the clinical effectiveness of a minimally invasive vertebral augmentation procedure, Radiofrequency-Targeted Vertebral Augmentation (RF-TVA) as compared to…
- Trial name
- PRIORi-T (NCT01480167)
- Testing
- Vertebral Augmentation (STABILIT), Non-operative Management
- Where
- 6 sites in United States
- Sponsor
- DFINE Inc.
Fracture, Healed, Fibrous Union
Mid-term Outcome Following Revision Surgery of Clavicular Non- and Malunion
Background Treatment of clavicular non- and malunion is still challenging. Current surgical procedures often result in partially frustrating functional outcome along with high-grade subjective impairment and increased rates of…
- Trial name
- Nonunion (NCT02951468)
- Testing
- LCP plus iliac crest autograft
- Volunteers
- 14 people
- Sponsor
- Technical University of Munich
Ankle Fractures
Compression in Anklefracture Treatment, The CAT-study
The aim of this project is to find out if compression treatment can lower the incidens of surgical wound complications, such as infection and wound rupture, in patients with ankle fractures.
- Trial name
- CAT (NCT02481076)
- Testing
- Flowtron Hydroven and Coban2 Lite, Braun frame, compression bandage
- Where
- Denmark
- Volunteers
- 156 people
- Sponsor
- Hillerod Hospital, Denmark
Hand, Hand Therapy
Early Functional Response as a Predictor of Clinical Outcomes in Hand Rehabilitation: A Prospective Feasibility Study Using a Digital Monitoring System
This study investigates whether early changes observed during the first weeks of hand and upper extremity rehabilitation can predict patient outcomes months later.
- Conditions
- Hand, Hand Therapy, Upper Extremity, Prediction Models
- Trial name
- HANDREHPREDICT (NCT07522060)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Hacettepe University