Clinical trials: Compression Neuropathy
Amyotrophic Lateral Sclerosis, Frontotemporal Dementia
Phenotype, Genotype & Biomarkers in ALS and Related Disorders
The goals of this study are: (1) to better understand the relationship between the phenotype and genotype of amyotrophic lateral sclerosis (ALS) and related diseases, including primary lateral sclerosis (PLS), hereditary spastic…
- Conditions
- Amyotrophic Lateral Sclerosis, Frontotemporal Dementia, Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
- Trial name
- NCT02327845
- Where
- 15 sites in United States, Germany and 1 more
- Volunteers
- 708 people, healthy volunteers welcome
- Sponsor
- University of Miami
Carpal Tunnel Syndrome
Does a Different Local Anesthetic Improve Pain After Carpal Tunnel Release?
This study is being conducted to determine whether addition of a longer-acting local anesthetic to our current anesthetic protocol improves the post-operative pain after carpal tunnel release.
- Trial name
- NCT04833777
- Testing
- Local Anesthetics Lidocaine, Local Anesthetics Bupivacaine
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Carpal Tunnel Syndrome
Ultrasound Analysis of Human Carpal Tunnel System
This study evaluates the ability of ultrasound to measure the movement of tendons and nerves within the human carpal tunnel.
- Trial name
- NCT02747836
- Testing
- Ultrasound of the wrist
- Where
- United States
- Volunteers
- 257 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Piriformis Syndrome
Effects of Soft Tissue Mobilization Technique and Piriformis Muscle Stretching Among Patients Having Piriformis Syndrome
It is a randomized control trail in which soft tissue mobilization and piriformis stretching will be compared and study duration will be of five months
- Trial name
- NCT05680402
- Testing
- Soft Tissue mobilization, Piriformis Syndrome (Piriformis muscle stretching)
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Neuro Counsel Hospital, Pakistan
Chronic Kidney Disease, Renal Osteodystrophy
Serum Sclerostin Levels, Cardiovascular Parameters and Carpal Tunnel Syndrome in Maintenance Hemodialysis Patients
Sclerostin, the product of the SOST gene, located on chromosome 17, locus q11.2 in humans, was originally believed to be a non-classical Bone morphogenetic protein (BMP) antagonist.Sclerostin was recently identified as a…
- Conditions
- Chronic Kidney Disease, Renal Osteodystrophy, Left Ventricular Hypertrophy
- Trial name
- NCT01382966
- Where
- Turkey (Türkiye)
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- RFM Renal Treatment Services
Carpal Tunnel Syndrome, Entrapment Neuropathies
Median Nerve Cross-Sectional Area and Body Weight in Carpal Tunnel Syndrome
This study aims to evaluate the diagnostic accuracy of ultrasonographic measurements of the median nerve in patients with Carpal Tunnel Syndrome (CTS).
- Conditions
- Carpal Tunnel Syndrome, Entrapment Neuropathies, Median Nerve Compression
- Trial name
- CTS-US-WEIGHT (NCT07508397)
- Testing
- High-Resolution Ultrasonography and Electrophysiological Evaluation
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Spinal Muscular Atrophy, Charcot-Marie-Tooth Disease
Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
The goal of this study is to establish a genetic registry of patients with early-onset motor neuron and neuromuscular diseases. The investigators will collect samples from patients with a motor neuron or a neuromuscular disorder…
- Conditions
- Spinal Muscular Atrophy, Charcot-Marie-Tooth Disease, Muscular Dystrophy, Spinal Muscular Atrophy With Respiratory Distress 1
- Trial name
- NCT02532244
- Testing
- sample collection
- Where
- 3 sites in United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
CMT, CMT (Charcot Marie Tooth Disease)
TREMOR IN CHARCOT-MARIE-TOOTH
Tremor is a symptom that has already been described in many case reports and case series concerning patients with Charcot-Marie-Tooth (CMT) disease.
- Conditions
- CMT, CMT (Charcot Marie Tooth Disease), Charcot Marie Tooth Disease (CMT), Charcot Marie Tooth Disease
- Trial name
- CMT-TREM (NCT07570459)
- Where
- Germany
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University Medical Center Goettingen
Primary Lateral Sclerosis, Hereditary Spastic Paraplegia
Nuclear Magnetic Spectroscopy Imaging to Evaluate Primary Lateral Sclerosis, Hereditary Spastic Paraplegia and Amyotrophic Lateral Sclerosis
This study will use a magnetic resonance imaging technique called nuclear magnetic spectroscopy (H-MRS) to define the pathology and progression of primary lateral sclerosis, hereditary spastic paraplegia and amyotrophic lateral…
- Conditions
- Primary Lateral Sclerosis, Hereditary Spastic Paraplegia, Amyotrophic Lateral Sclerosis
- Trial name
- NCT00023075
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Charcot Marie Tooth Disease
Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C…
- Trial name
- INC-6601 (NCT01193075)
- Where
- 24 sites in United States, Australia and 4 more
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Michael Shy
Carpal Tunnel Syndrome
Ultrasonographic Measurements of the Median Nerve Before and After Splinting for Carpal Tunnel Syndrome
A prospective cohort follow-up study design is undertaken. Both males and females with mild to moderate carpal tunnel syndrome will receive standard-of-care wrist splint for 6 weeks and undergo follow up studies for data…
- Trial name
- NCT02038205
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Carpal Tunnel Syndrome
Topical Cannabidiol for Treating Carpal Tunnel Syndrome
The Purpose of this study is to assess the safety and efficacy of Cannabidiol on treatment of Carpal Tunnel Syndrome.
- Trial name
- NCT06108349
- Testing
- Cannabidiol
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Piriformis Syndrome
Effects of Global Hip Versus Isolated Abductors Strengthening Exercises in Patients Withsecondary Piriformis Syndrome
The study will be a randomized controlled trial. Twenty-four subjects will be assigned randomly by using the lottery method into two groups.
- Trial name
- NCT05848063
- Testing
- Global hip muscles strengthening exercises, Hip abductors strengthening exercises
- Where
- Pakistan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Amyotrophic Lateral Sclerosis (ALS)
Developing New Ways to Detect Respiratory Impairment Early in ALS
The goal of this observational study is to develop new ways to detect early changes associated with amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease.
- Trial name
- NCT07844590
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Carpal Tunnel Syndrome
Lipografting Versus Steroid Injections for Treatment of Carpal Tunnel Syndrome
This study applies the regenerative properties of autologous fat transfer to treat mild to moderate carpal tunnel syndrome in comparison to the current standard of care, corticosteroid treatment.
- Trial name
- NCT03722303
- Testing
- Fat Injection, Steroid Injection
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Columbia University
Neurofilament Light Chain, Glial Fibrillary Acidic Protein
Analysis of NfL and GFAP in Different Dietary Patterns
This observational study aims to investigate the impact of different dietary patterns on brain tissue biomarkers in healthy young adults by measuring blood levels of NfL and GFAP.
- Conditions
- Neurofilament Light Chain, Glial Fibrillary Acidic Protein, GFAP, Vegan Diet
- Trial name
- NCT07312994
- Where
- Austria
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Salzburger Landeskliniken
Carpal Tunnel Syndrome, Compare Steroids Versus PRP in Dissection of Median Nerve by Ultrasound
Ultrasound Guided Activated and Non Activated Platelet Rich Plasma Injection Versus Hydro Dissection by Steroids.
PRP represents a promising, nonsurgical option for patients with carpal tunnel syndrome (CTS) with improvement in symptoms compared to placebo, conservative treatment, and local corticosteroid injections at 3-months…
- Trial name
- PRP (NCT06249503)
- Testing
- platelet rich plasma
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Thoracic Outlet Syndrome
Systematic Transcutaneous Oxymetry Use in Thoracic Outlet Syndrome
The measurement of the transcutaneous oxygen partial pressure (TCPO2) at exercise is, to our knowledge, the only method to estimate during the exercise the importance of ischemia segment of limb by segment of limb bilaterally and…
- Trial name
- STOUT (NCT03355274)
- Testing
- Transcutaneous Oximetry, Photopletysmography, Questionnaires of Quality of Life (QoL)
- Where
- France
- Volunteers
- 222 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Thoracic Outlet Syndrome
The Effectiveness of Diagnosis and Treatment of Thoracic Outlet Syndrome
Thoracic Outlet Syndrome (TOS) is a condition causing numbness, tingling and weakness in patient's upper limbs. Symptoms are due to compression and restriction of the nerves and blood vessels (neurovascular bundle) that extend…
- Trial name
- NCT01342068
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Nova Southeastern University
Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Vasculitic Neuropathy
Polyneuropathy, Impairments and Physical Activity - The PolyImPAct Study
The project aims to investigate the validity, and reliability of outcome measures of muscle strength, functioning (gait, balance, and fine motor skills), physical activity, and patient-reported outcome measures of functioning…
- Conditions
- Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Vasculitic Neuropathy, POEMS Syndrome, Multifocal Motor Neuropathy
- Trial name
- PolyImPAct (NCT06040567)
- Testing
- Validity and reliability of outcome measures in polyneuropathy, Healthy controls
- Where
- Denmark
- Volunteers
- 520 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet