Clinical trials: Compulsive Behavior, open to volunteers
Social Media Addiction, Self Esteem
ACT-Based Psychoeducation for Youth With Social Media Addiction
While social media offers opportunities for connection and self-expression, it also brings significant challenges, particularly social media addiction, characterized by excessive and uncontrolled use.
- Conditions
- Social Media Addiction, Self Esteem, Interpersonal Problem, Problem-solving
- Trial name
- ACT-SM (NCT07343180)
- Testing
- ACT-Based Psychoeducational Program
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Kahramanmaras Sutcu Imam University
Addiction
Trajectories and Reactions of Users and Relatives Consulting French Youth Addiction Services
In France, the "Consultations Jeunes Consommateurs" (CJC) are the services specialized in the reception of young people for addiction problems. There are more than 500 CJCs throughout France.
- Trial name
- TRYAD (NCT05609474)
- Where
- France
- Volunteers
- 1,430 people
- Sponsor
- Hôpital le Vinatier
Methamphetamine Abuse, Methamphetamine-dependence
Feasibility of Long-term, High-dose Stimulant for Methamphetamine Use Disorder
Methamphetamine use disorder (MUD) is becoming an increasing public health concern in Canada. While the evidence on the efficacy and safety of prescription psychostimulants for the treatment of MUD is promising, the knowledge on…
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance Abuse
- Trial name
- NCT06788587
- Testing
- LDX-01 plus TAU
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders
Testing Delivery Modalities of Team-Based CBT for Pediatric Anxiety in Community Health Settings.
The purpose of this study is to test how the delivery of Cognitive Behavioral Therapy (CBT) for pediatric anxiety and OCD via different methods might increase its availability and effectiveness.
- Conditions
- Obsessive Compulsive Disorder (OCD), Pediatric Anxiety Disorders, Anxiety Disorder, Anxiety
- Trial name
- IMPACT-RI (NCT06934525)
- Testing
- Team-delivered, exposure-based CBT
- Where
- United States
- Volunteers
- 501 people
- Sponsor
- Bradley Hospital
Obesity
Abnormal Eating and Taste Perception in Subjects With Obesity
The identification of safe and effective strategies for weight loss and long-term maintenance is critical to reduce the alarming prevalence of obesity worldwide and mitigate obesity-associated health risks.
- Trial name
- TASTEOB (NCT05772052)
- Where
- Italy
- Volunteers
- 300 people
- Sponsor
- Istituto Auxologico Italiano
D000096704, Cannabinoid Hyperemesis Syndrome
Cannabinoid Hyperemesis Syndrome. Prospective Multicenter Study of Patients Admitted to Adult Emergency Departments in Maine-et-Loire.
Cannabinoid hyperemesis syndrome (CHS) is characterized by incoercible abdominal pain and vomiting in patients with chronic cannabis use. Patients are relieved by hot showers, an easily performed diagnostic test.
- Trial name
- CANN-AIE (NCT06660901)
- Where
- 3 sites in France
- Volunteers
- 3,000 people
- Sponsor
- University Hospital, Angers
Alcohol Use Disorder
Impulsivity Domains and Subjective Response
Findings from this project will determine the relationship between two vulnerability factors for Alcohol Use Disorder (AUD) in young adults: impulsivity and subjective response to alcohol.
- Trial name
- NCT05929677
- Testing
- Alcohol
- Where
- 2 sites in United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jessica Weafer
HIV Infections, Substance Use Disorders
Syringe Service Based Telemedicine and Social Network Driven HIV Prevention Service Implementation
The goal of this clinical trial is to evaluate the effectiveness of a social network intervention to recruit people who inject drugs and their networks for HIV testing and linkage to HIV prevention and treatment services in…
- Conditions
- HIV Infections, Substance Use Disorders, Addiction, Opioid Use
- Trial name
- NCT06103370
- Testing
- Peer-educator-based network
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Johns Hopkins University
Obsessive-Compulsive Disorder
MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)
The study assesses the safety and preliminary effectiveness of MDMA-assisted cognitive behavioral therapy in participants diagnosed with obsessive-compulsive disorder (OCD).
- Trial name
- MDMA-CBT4OCD (NCT05783817)
- Testing
- 3,4-Methyl enedioxy methamphetamine, Methamphetamine, Cognitive Behavioral Therapy (CBT)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Carolyn Rodriguez
Obsessive-Compulsive Disorder, Virtual Reality
The Effect of Immersive Virtual Reality Treatment With Cognitive Behaviour Therapy for Obsessive-Compulsive Disorder
This study will evaluate the clinical effectiveness ofthe Immersive Virtual Reality alongside exprosure and response Prevention (ERP) Treatment in cognitive-Behavioral Therapy for Obsessive-compulsive Disorder, and the underlying…
- Trial name
- NCT04534907
- Testing
- The combination of exposure and response prevention (ERP) and VR, Traditional ERP
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai Mental Health Center
Smoking Cessation, Smoking (Tobacco) Addiction
PASCAL Feasibility Study
The goal of this randomized study is to assess if a conversational agent (or chatbot) that the investigators have developed to help with quitting smoking is acceptable to people trying to quit smoking and to also collect initial…
- Trial name
- NCT07301151
- Testing
- chatbot, no chatbot
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of Minnesota
Addiction
Support Towards Addiction Recovery for Individuals With Criminal Legal System Involvement: The STAR Project
The goal of this clinical trial is to determine whether a new, paired coaching intervention improves outcomes for individuals with criminal legal system involvement recovering from substance use disorder, as well as the loved…
- Trial name
- NCT07596251
- Testing
- STAR Intervention
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Martha Tillson
Attention Deficit Hyerpactivity Disorder, Smartphone Addiction
Reducing Smartphone Overuse for Adolescents With Attention-Deficit Hyperactive Disorder
This study will develop and evaluate a smartphone-based behavioral intervention for adolescents with Attention-Deficit Hyperactive Disorder (ADHD) and smartphone overuse in Hong Kong.
- Trial name
- NCT07092787
- Testing
- Smartphone-based behavioral intervention, Self-monitoring of smartphone use
- Volunteers
- 120 people
- Sponsor
- Education University of Hong Kong
Major Depressive Disorder, Obsessive-Compulsive Disorder
Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental Illness
Participants will receive Transcranial Magnetic Stimulation (TMS) at a random location in the left prefrontal cortex, excluding sites that are potentially unsafe.
- Conditions
- Major Depressive Disorder, Obsessive-Compulsive Disorder, Schizophrenia, Generalized Anxiety Disorder
- Trial name
- Expedition (NCT06376734)
- Testing
- Transcranial magnetic stimulation
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Brigham and Women's Hospital
Alcohol Drinking, Cannabis Use
Cannabis' Impact on Alcohol Consumption
This study employs a repeated measures experimental design to examine the effect of THC-dominant dose of cannabis and CBD-dominant dose of cannabis, relative to placebo, on subsequent drinking in an alcohol choice task in which…
- Conditions
- Alcohol Drinking, Cannabis Use, Cannabis, Alcohol Use Disorder
- Trial name
- NCT05389930
- Testing
- THC-dominant cannabis, CBD-dominant cannabis, Alcohol
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Brown University
Methamphetamine Abuse, Methamphetamine-dependence
Clinical Trial of High Dose Lisdexamfetamine and Contingency Management in MA Users
The goal of this clinical trial is to learn if administering a high dose stimulant with Contingency Management reduces days of use in adults who use methamphetamine better than the usual treatment provided by the clinic.
- Conditions
- Methamphetamine Abuse, Methamphetamine-dependence, Addiction, Substance, Addiction
- Trial name
- NCT05854667
- Testing
- Treatment as Usual plus lisdexamfetamine (LDX-01), Treatment as Usual plus lisdexamfetamine (LDX-01) plus Contingency Management
- Where
- 4 sites in Canada
- Volunteers
- 440 people, healthy volunteers welcome
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Obsessive Compulsive Disorder
Precision Analytic Research Methods in OCD
Psychiatric disorders characterized by compulsivity, such as obsessive-compulsive disorder (OCD), result in considerable functional impairment and many individuals do not respond to gold-standard treatments.
- Trial name
- NCT07011901
- Testing
- Exposure and Response Prevention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Substance Use Disorder (SUD), Opioid Use Disorder (OUD)
Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder
The purpose of this study is to determine if personalized (adaptive) Deep Brain Stimulation (DBS) based upon invasive brain mapping is safe and can lead to better outcomes like reductions in craving and opioid use.
- Trial name
- aDBS OUD (NCT07214467)
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- University of California, San Francisco
Addiction
Vocal Biomarkers of Craving
Addiction is a psychiatric disorder associated with craving, an unwanted, intense and persistent desire to use the substance/addictive behavior, leading to frequent relapses.
- Trial name
- IVOMOC (NCT07878624)
- Testing
- Cue reactivity paradigm, Ecological momentary assessment
- Where
- France
- Volunteers
- 120 people
- Sponsor
- University of Bordeaux
Obsessive Compulsive Disorder (OCD), Bipolar Disorders
Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions
This is a research study looking at whether the way people speak can help predict how well they'll respond to certain mental health treatments.
- Conditions
- Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD
- Trial name
- NCT06823024
- Where
- 2 sites in United States
- Volunteers
- 200 people
- Sponsor
- Psyrin Inc.