Clinical trials: Compulsive Disorder
Obsessive Compulsive Disorder (OCD)
Transcutaneous Electrical Acupoint Stimulation Combined With Exposure and Response Prevention in the Treatment of Patients With Obsessive-Compulsive Disorder: A Randomized Controlled Trial
Obsessive-compulsive disorder is a chronic and disabling mental disorder. Among them, 40-60% of obsessive-compulsive disorder patients do not respond to the current first-line drug treatment and/or psychological therapy.
- Trial name
- NCT07811778
- Testing
- Exposure and Response Prevention, Active Transcutaneous Acupoint Electrical Stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-compulsive Disorders and Symptoms
tDCS Stimulation to Treat Patients With Severe and Resistant Obsessive Compulsive Disorder-Pilot Study
The purpose is to show that bifocal tDCS with an anodal stimulation on the orbitofrontal cortex and cathodic stimulation on supplementary motor areas is an effective treatment for patients with resistant and severe obsessive…
- Trial name
- tDCS-TOC (NCT03284671)
- Testing
- bifocal stimulation with tDCS
- Where
- France
- Volunteers
- 20 people
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive-Compulsive Disorder
tDCS for Treatment Resistant Obsessive Compulsive Disorder
It's a multicentric, randomized, controlled study concerning 100 patients with treatment-resistant obsessive compulsive disorders (OCD).
- Trial name
- tDCS-TOC (NCT03304600)
- Testing
- Active stimulation
- Where
- 4 sites in France
- Volunteers
- 83 people
- Sponsor
- Centre Hospitalier Henri Laborit
Obsessive-Compulsive Disorder
Treating Adolescent Obsessive Compulsive Disorder With Transcranial Magnetic Stimulation
This is a pilot study to examine the tolerability, safety and early efficacy of two forms of transcranial magnetic stimulation (TMS) for treating adolescents with Obsessive Compulsive Disorder (OCD) who have experienced limited…
- Trial name
- NCT07065669
- Testing
- Dorsal medial Prefrontal Cortex intermittent theta burst stimulation, cTBS to ROFC
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Obsessive Compulsive Disorder (OCD)
Bergen Four-Day Treatment (B4DT) for Obsessive-Compulsive Disorder
The aim of this study is to expand access to Bergen Four-Day Treatment (B4DT) in Finland and to integrate it into psychiatric care pathways at Tampere University Hospital (TAYS).
- Trial name
- NCT07644130
- Testing
- Bergen Four-Day Treatment (B4DT)
- Where
- Finland
- Volunteers
- 65 people
- Sponsor
- Tampere University Hospital
Obsessive-Compulsive Disorder
Transcranial Direct Current Stimulation Potentiation of Fear Extinction in OCD
The investigators want to learn more about how human beings learn not to fear and the impact of changing the fear network in the brain using transcranial Direct Current Stimulation (tDCS) in individuals with obsessive compulsive…
- Trial name
- NCT05521074
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Massachusetts General Hospital
Obsessive-Compulsive Disorder
Effects of Psilocybin in Obsessive Compulsive Disorder
This study will test the feasibility, safety, and evidence for efficacy of psilocybin administration in participants with obsessive compulsive disorder (OCD).
- Trial name
- NCT05546658
- Testing
- Psilocybin
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Johns Hopkins University
Obsessive - Compulsive Disorder
Efficacy and Mechanism of Transcranial Temporal Interference Stimulation (tTIS) for Patients With Obsessive-Compulsive Disorders
Targeted temporal interference stimulation (tTIS) of the nucleus accumbens (NAc) may modulate the abnormal electrophysiological activity in individuals with obsessive-compulsive disorder (OCD), thereby improving their…
- Trial name
- NCT07805200
- Testing
- Transcranial Temporal Interference Stimulation
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing HuiLongGuan Hospital
Anxiety, Panic Disorder
The Use of a FDA Cleared, Drug-free, Breathing System for Anxiety and Panic Disorders in Children and Teens
This study will test the efficiency of the Freespira Breathing System in youth.
- Trial name
- NCT02998502
- Testing
- Freespira Breathing System
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Johns Hopkins University
OCD, Obsessive-Compulsive Disorder
Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE)
The investigators propose to synchronize automated measurements of behavior - head, body, and face dynamics, gaze, and vocal prosody - with simultaneous recordings of brain activity in clinically relevant contexts.
- Trial name
- ABOVE (NCT03459456)
- Testing
- Provocation OC task (Provoc), Trier Social Stress Test (TSST), Exposure provocation task
- Where
- 3 sites in United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Phase II Adaptive Deep Brain Stimulation for Obsessive-Compulsive Disorder
This research study is for participants that have been diagnosed with intractable Obsessive -compulsive disorder (OCD). OCD is a persistent and oftentimes disabling disorder marked by unwanted and distressing thoughts…
- Trial name
- NCT04806516
- Testing
- Summit RC+S System with ECoG Paddles, One Month Blinded Discontinuation Period:
- Where
- 3 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Obsessive-Compulsive Disorder
Imaging-Guided Low Intensity Focused Ultrasound (LIFU)
This research study is to investigate the safety, feasibility, and possible therapeutic benefits of a technology called Low Intensity Focused Ultrasound (LIFU) in patients with obsessive- compulsive disorder (OCD).
- Trial name
- LIFU (NCT05467085)
- Testing
- BX Pulsar 1002
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- Baylor College of Medicine
Sexual Addiction
Prevalence of Sexual Addiction in an Inmate Population at the Muret Detention Center in Haute-Garonne (PAS-CD)
Sexual addiction, also known as hypersexuality or compulsive sexuality, is a human sexual behavior that results in a continuous and persistent search for sexual pleasure.
- Trial name
- PAS-CD (NCT05483426)
- Testing
- semi-structured Interviews
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Federation Regionale de Recherche en Psychiatrie et Sante Mentale Occitanie
Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood
Evaluation of Family-Based Behavioral Treatments for Youth With Anxiety and Obsessive-Compulsive Disorder
Anxiety and obsessive-compulsive disorders are among the most common in children. Although cognitive behavioral therapy (CBT) is an effective and evidence-based treatment for such disorders, access to CBT is often limited.
- Conditions
- Obsessive-Compulsive Disorder in Children, Anxiety Disorder of Childhood, Social Anxiety Disorder of Childhood, Obsessive-Compulsive Disorder in Adolescence
- Trial name
- NCT05967468
- Testing
- Family Based, Internet-Based Cognitive Behavioral Therapy, Bibliotherapy, low therapist contact SPACE, Relaxation and Mentorship
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Baylor College of Medicine
Parkinson's Disease, Obsessive Compulsive Disorder
Physiological Brain Atlas Development
The NIH grant has funded the development of a physiological brain atlas registry that will allow us to significantly improve the data collectioin and use of physiological data into a normalized brain volume.
- Conditions
- Parkinson's Disease, Obsessive Compulsive Disorder, Dystonia, Essential Tremor
- Trial name
- Brain Atlas (NCT00575081)
- Testing
- Stereotactic brain procedures
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Vanderbilt University Medical Center
Deep Brain Stimulation
Efficacy and Safety of Combo-stim Deep Brain Stimulation for Treatment-refractory Mental Disorders
This is a multi-center, single arm, prospective, open-label, extendable study for the efficacy and safety of combo-stim deep brain stimulation for treatment-refractory mental disorders (obsessive-compulsive disorder…
- Trial name
- NCT06112067
- Testing
- deep brain stimulation
- Where
- China
- Volunteers
- 18 people
- Sponsor
- Shanghai Mental Health Center
Anxiety, Anxiety Acute
Anxiety Skills Study
The purposes of this study are: (1) to identify baseline predictors of relative success in cognitive, behavioral, and mindfulness-based treatments for anxiety, (2) explore who benefits from a brief, video-based skill training…
- Conditions
- Anxiety, Anxiety Acute, Anxiety Chronic, Anxiety and Mood Disorders
- Trial name
- NCT07774481
- Testing
- Cognitive therapy, Behavioral therapy, Mindfulness-based therapy
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Ohio State University
OCD
Light Therapy for Obsessive-compulsive Disorder (OCD)
The goal of this clinical trial is to test whether light therapy is effective for reducing symptoms in young adults with OCD and late bedtimes (1am or later).
- Trial name
- KLTO (NCT06720090)
- Testing
- Light therapy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Obsessive-Compulsive Disorder
Understanding How Ketamine Brings About Rapid Improvement in OCD
The purpose of this study is to understand how ketamine brings about rapid improvement in Obsessive-Compulsive Disorder (OCD) symptoms.
- Trial name
- MKET (NCT02624596)
- Testing
- Ketamine, Midazolam
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Stanford University
Obsessive Compulsive Disorder
Computerized Training for Individuals Diagnosed With Obsessive-Compulsive and Related Disorders
Obsessive-Compulsive Disorder (OCD) is a chronic and disabling disorder that costs the economy over $2 billion annually and represents a significant public health problem.
- Trial name
- EmRT (NCT03182075)
- Testing
- Computerized Training
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stanford University