Clinical trials: Compulsive Disorder
Obsessions, Suicide
Obsessions and Suicidality in Youth With Bipolar 1 Disorder
Obsessive-compulsive disorder (OCD) is a common co-morbidity with bipolar I disorder, a comorbidity that is known to increase suicide risk.
- Conditions
- Obsessions, Suicide, Bipolar I Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT05878808
- Testing
- Psychometric assessment
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Hoarding Disorder
Group Treatment for Hoarding Disorder
This study assesses the effectiveness of a novel group treatment for hoarding disorder.
- Trial name
- NCT04270825
- Testing
- Group CBT with IPT
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Florida State University
Obsessive-Compulsive Disorder, Transcranial Magnetic Stimulation
Repetitive Transcranial Magnetic Stimulation (rTMS) Treatment for Obsessive Compulsive Disease
To investigate the treatment effect of repetitive transcranial magnetic stimulation on Obsessive-compulsive disorder, and the underlying neural mechanism by functional MRI.
- Conditions
- Obsessive-Compulsive Disorder, Transcranial Magnetic Stimulation, Functional Magnetic Resonance Imaging, Event-Related Potentials
- Trial name
- NCT03393078
- Testing
- transcranial magnetic stimulation with real coil
- Where
- China
- Volunteers
- 37 people
- Sponsor
- Anhui Medical University
Emotional Regulation, Depression
A Precision Medicine Approach to Target Engagement for Emotion Regulation
The proposed study is designed to first test whether teaching people personalized or standardized emotion regulation skills leads to greater decreases in daily negative emotion intensity.
- Conditions
- Emotional Regulation, Depression, Anxiety, Borderline Personality Disorder
- Trial name
- NCT05651295
- Testing
- Checking the Facts, Opposite to Emotion Action, Mindfulness of Current Emotions
- Where
- United States
- Volunteers
- 390 people
- Sponsor
- Matthew Southward, PhD
Obsessive-Compulsive Disorder (OCD)
Preliminary Explorative Study of Magnetic Resonance-Guided Focused Ultrasound Surgery in Refractory Obsessive-Compulsive Disorder Patients
The goal of this clinical trial is to evaluate If magnetic resonance-guided focused ultrasound works to treat refractory obsessive-compulsive disorder in adults.
- Trial name
- NCT06816511
- Testing
- magnetic resonance-guided focused ultrasound surgery, MRgFUS
- Where
- Taiwan
- Volunteers
- 10 people
- Sponsor
- National Taiwan University Hospital
Obsessive-Compulsive Disorder
The Study of Mindfulness Based Cognitive Therapy and Obsessive-Compulsive Disorder
The primary objective of the study is to evaluate the clinical curative effect of MBCT to reduce obsessive and compulsive symptoms.
- Trial name
- NCT03179839
- Testing
- Mindfulness-based Cognitive Therapy, Psycho-education Program, sertraline, fluvoxamine
- Where
- China
- Volunteers
- 123 people
- Sponsor
- Shanghai Mental Health Center
Obsessive-Compulsive Disorder
Comparison of DBS Targets in Obsessive-compulsive Disorder
Deep brain stimulation (DBS) has been proposed for severe and resistant obsessive-compulsive disorder. This electrical stimulation has been tested on, and shown to be effective at, different targets (subthalamic nucleus, caudate…
- Trial name
- PRESTOC2 (NCT01807403)
- Testing
- Deep brain stimulation
- Where
- France
- Volunteers
- 8 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Addiction
Safety and Tolerability of Cannabidiol Among Persons With Opioid Use Disorder Receiving Methadone or Buprenorphine
The overarching goal of this study is to evaluate the potential of Cannabidiol (CBD) as an adjunctive treatment for comorbid opioid use disorder (OUD) and chronic pain.
- Trial name
- NCT05076370
- Testing
- CBD Day 1, CBD Day 2, CBD Day 3
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Yale University
Depression, Addiction
Providing Mental Health Precision Treatment
This research study is being conducted to understand if patients benefit from mobile health interventions while waiting for in-clinic mental health treatments, and to understand which patients receive the most benefit.
- Conditions
- Depression, Addiction, Anxiety, Sleep Disturbance
- Trial name
- PROMPT (NCT04342494)
- Testing
- Enhanced Feedback + Standard Feedback, Headspace app + Standard Feedback, Headspace app + Enhanced Feedback + Standard Feedback
- Where
- United States
- Volunteers
- 2,118 people
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder
Targeted Circuit-Based Transcranial Focused Ultrasound Intervention for Obsessive-Compulsive Disorder TUS-OCD
This study explores the potential of transcranial ultrasound stimulation (TUS) as an innovative therapeutic approach for individuals with obsessive-compulsive disorder (OCD).
- Trial name
- TUS-OCD (NCT06722339)
- Testing
- low intensity transcranial focused ultrasound stimulation (TUS)
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- University of Plymouth
Obsessive-Compulsive Disorder
N-Acetylcysteine Augmentation in Treatment-Refractory Obsessive-Compulsive Disorder
Obsessive-compulsive disorder (OCD) affects 2-3% of the population and leads to a great deal of suffering. Many patients benefit from established treatments, the mainstay of which are cognitive behavioral therapy and a group of…
- Trial name
- NCT00539513
- Testing
- N-Acetylcysteine
- Volunteers
- 10 people
- Sponsor
- Yale University
Digital Technology Use, Social Media Addiction
Improving Digital Wellbeing in Saudi Adolescents
Background: In Saudi Arabia, the rapid expansion of digital technology use-particularly among adolescents-has raised growing concerns about internet addiction and its impact on mental health and overall wellbeing.
- Conditions
- Digital Technology Use, Social Media Addiction, Internet Gaming Disorder
- Trial name
- NCT07344142
- Testing
- Digital Wellbeing Unit, Parent WhatsApp Groups, Online Teacher Training
- Where
- Saudi Arabia
- Volunteers
- 2,600 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins Bloomberg School of Public Health
Internet Gaming Disorder
Investigation of the Relationship Between Internet Gaming Disorder and Sensorimotor Functions in Adolescents
Using computer for long have been shown to cause vision problems, musculoskeletal pain particularly in neck, postural deviations, obesity and physical inactivity in several studies.
- Trial name
- NCT04631523
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Opiate Addiction, Medication Non-adherence
Using Artificial Intelligence To Monitor Medication Adherence in Opioid Replacement Therapy
This study uses an artificial intelligence platform to automatically confirm medication ingestion. The Health Insurance Portability and Accountability Act (HIPAA)-compliant platform can be downloaded as an 'app' onto any…
- Conditions
- Opiate Addiction, Medication Non-adherence, Addiction, Opioid Dependence
- Trial name
- NCT02243670
- Testing
- AiCure monitoring and intervention
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- AiCure
Obsessive Compulsive Disorder (OCD)
Artificial Intelligence-Powered Virtual Reality Exposure Therapy for OCD in College Students: A Proof-of-Concept Study
This research study is being conducted to study the use of artificial-intelligence powered virtual reality exposure therapy (AI-VRET) to treat college students with obsessive compulsive disorder (OCD).
- Trial name
- AI-VRET (NCT07877363)
- Testing
- Traditional Exposure and Response Prevention (ERP), Artificial Intelligence-Powered Virtual Reality Exposure Therapy (AI-VRET)
- Volunteers
- 24 people
- Sponsor
- University of California, San Diego
Anxiety Disorders, Post Traumatic Stress Disorder
Increasing Treatment Efficacy Using SMART Methods for Personalizing Care
The proposed study will determine the feasibility, tolerability, and acceptability of a study that tests: 1) personalized treatment delivery (i.e., module sequencing and treatment discontinuation timing) aimed at increasing the…
- Conditions
- Anxiety Disorders, Post Traumatic Stress Disorder, Obsessive-Compulsive Disorder
- Trial name
- NCT04642898
- Testing
- Standard UP Treatment, Capitalization UP Treatment, Compensation UP Treatment
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Shannon E. Sauer-Zavala
Food Addiction, Withdrawal
The Biobehavioral Impact of Diet Quality on Affect and Craving
The current study experimentally investigates whether reducing highly processed (HP) foods (defined in this study as foods high in added sugars) leads to, psychological and / or behavioral indicators of withdrawal.
- Trial name
- NCT04105712
- Testing
- Dietary Change (low in highly processed foods)
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Obsessive-Compulsive Disorder
Mindfulness-Based Interventions for OCD
Obsessive-compulsive disorder (OCD) is a severe and debilitating anxiety disorder afflicting about 2% of the population. It is characterized by the presence of recurrent obsessions and/or compulsions that are time consuming and…
- Trial name
- MindOC (NCT04914923)
- Testing
- Muse, Cognitive Behaviour Therapy (CBT), Mindfulness-Based Cognitive Therapy (MBCT)
- Where
- 2 sites in Canada
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Sunnybrook Health Sciences Centre
Alcoholism
Oxytocin in Alcohol Use Disorder
Background: Oxytocin is a naturally occurring substance in the body. Studies show that oxytocin may affect how the body responds to alcohol. Researchers believe oxytocin may be a possible treatment for alcoholism.
- Trial name
- NCT02711189
- Testing
- Oxytocin
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Obesity & Overweight, Cardiometabolic Health Indicators
Tirzepatide Impact Assessment Study
This study examines how two different weight-loss strategies affect heart and metabolic health, as well as changes at the molecular level in the body.
- Conditions
- Obesity & Overweight, Cardiometabolic Health Indicators, Addiction, Eating Disorders
- Trial name
- TIA (NCT07740291)
- Testing
- GLP-1 Receptor Agonist Therapy, Structured Lifestyle Intervention
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Texas Tech University