Clinical trials: Computed Tomography Scan
Lung Cancer, Lung Neoplasms
Feasibility and Uptake of Low-Dose CT Lung Cancer Screening in Kuwait
Lung cancer is a leading cause of cancer-related death in Kuwait, where most cases are diagnosed at an advanced stage and there is no national screening program.
- Trial name
- ALIA (NCT07766538)
- Testing
- Low-dose computed tomography (LDCT) lung cancer screening
- Where
- Kuwait
- Volunteers
- 590 people, healthy volunteers welcome
- Sponsor
- Sulaiman Khadadah
Necrotic Pulp, Periapical; Infection
Volume Assessment of the Periapical Healing Following Regenerative Endodontic Procedures Using Cone- Bean Computed Tomography
3D volume assessment was done to evaluate the periapical healing following REPs in mature teeth.
- Trial name
- NCT04646538
- Testing
- Regenerative Endodontics Procedures (REPs)
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Traumatic Brain Injury
Single Photon Emission Computed Tomography (SPECT) Imaging Study of Professional American Football Players
The investigators primary objective is to acquire preliminary data on one-hundred former NFL veterans with at least one full year of professional service using brain SPECT imaging in order to assess the degree to which NFL…
- Trial name
- NCT01515839
- Testing
- Multivitamin Supplement intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Amen Clinics, Inc.
Lung Cancer, High-Risk Cancer
Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration
Lung cancer is the leading cause of mortality in the world, and also in Taiwan.Despite the researches and availability in new therapies, it causes the highest mortality and is one of the most preventable cancers as well.
- Conditions
- Lung Cancer, High-Risk Cancer, Smoking, Pollution; Exposure
- Trial name
- TRIO (NCT05557487)
- Testing
- Low dose computed tomography
- Where
- 7 sites in Taiwan
- Volunteers
- 6,618 people, healthy volunteers welcome
- Sponsor
- Gee-Chen Chang
Coronary Artery Disease
CCTA to Optimize Diagnostic Yield of Invasive Angiography With AI
Coronary artery disease (CAD) is a leading cause of death. The gold-standard test used to diagnose CAD is invasive coronary angiography (ICA).
- Trial name
- CarDIA-AI (NCT06648239)
- Testing
- Usual Care, Centralized triage with risk score-based screening for obstructive CAD
- Where
- 3 sites in Canada
- Volunteers
- 251 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Displacement of Other Bone Devices, Implants and Grafts, Mechanical Complication of Other Bone Devices, Implants and Grafts
Influence of Low-level Laser Therapy on Stability and Displacement of Orthodontic Miniscrew Implants
The purpose of this study is to evaluate the effect of Low level laser therapy on stability and displacement of orthodontic miniscrew implants using two different force application protocols.
- Trial name
- NCT02891499
- Testing
- Low-level laser therapy, Mediate force application
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Jumping Gap Dimension at Maxillary Teeth
Jumping Gap Dimension at Maxillary Teeth: Cone-Beam Computed Tomography (CBCT) Study
To assess the important anatomical structures involved in the treatment planning of immediate implants, particularly the jumping gap distance at the different maxillary teeth in the esthetic zone using CBCT analysis.
- Trial name
- NCT04636385
- Testing
- Observational study no intervention
- Where
- Egypt
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Pathological Resorption of External Root
Orthodontic Treatment With Clear Aligner
Three-dimensional Assessment of Root Resorption following treatment with clear aligners using Cone Beam Computed Tomography Design: A randomized, controlled, crossover, double-blind clinical study including twenty six adult …
- Trial name
- NCT06410105
- Testing
- CLEAR ALIGNERS
- Where
- Syria
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Latakia University
Alzheimer Disease
Evaluation of [123I] MNI-330 and SPECT as a Marker of Beta-amyloid Protein Deposition
The main objectives of this proposal are as follows: To assess the dynamic uptake and washout of 123-I MNI-330, a potential imaging biomarker for β-amyloid burden in brain, using single photon emission computed tomography (SPECT)…
- Trial name
- NCT00657813
- Testing
- MNI-330 as a brain SPECT tracer of Beta-Amyloid
- Where
- United States
- Volunteers
- 3 people, healthy volunteers welcome
- Sponsor
- Institute for Neurodegenerative Disorders
Periapical Periodontitis, Treatment Outcome
2-year Treatment Outcomes of Teeth Estimated by Means of Periapical and Endodontic Status Scale
Objectives: Evaluation of endodontic treatment success is largely based on radiographical assessment of anatomical and treatment-related parameters of teeth with apical periodontitis (AP).
- Trial name
- NCT04495270
- Testing
- Analysis of treatment outcomes of teeth with apical periodontitis based on cone-beam computed tomography and estimated by means of Periapical and Endodontic Status Scale"
- Volunteers
- 128 people, healthy volunteers welcome
- Sponsor
- Lithuanian University of Health Sciences
Endodontic Disease, Tooth Resorption
Volumetric Analysis of Resorption Types on CBCT
More accurate management of resorption can be achieved thanks to the three-dimensions volumetric and linear analysis, and the axial classification presented in this study.
- Trial name
- NCT04617301
- Where
- Turkey (Türkiye)
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan University Training and Research Hospital
Malocclusion, Class I/II, Crowding
A Comparative Study Between Modified Miniscrew-Assisted Rapid Palatal Expander And Modified Rapid Palatal Expander in Molar Distalization Using Cone- Beam Computed Tomography
Comparative study between modified miniscrew-assisted rapid palatal expander and modified rapid palatal expander in molar distalization using CBCT.
- Conditions
- Malocclusion, Class I/II, Crowding, Maxillary First Molar Distalization
- Trial name
- MIDPAC (NCT07038902)
- Testing
- Group A: Modified Miniscrew-Assisted Rapid Palatal Expander (MARPE), Group B: Modified Rapid Palatal Expander (RPE)
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Pulmonary Nodules
Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules
AnchorDx is using circulating tumor DNA (ctDNA) methylation analysis by next-generation sequencing (NGS) to develop a blood-based assay for differentiating benign and malignant pulmonary nodules early.
- Trial name
- NCT03651986
- Testing
- ctDNA methylation analysis by NGS
- Where
- 23 sites in China
- Volunteers
- 10,560 people, healthy volunteers welcome
- Sponsor
- AnchorDx Medical Co., Ltd.
PET/CT
Positron Emission Tomography/Computed Tomography (PECT/CT) Double-Scanning Study
This study aims to collect clinical image data using the Omni 128 cm PET/CT system and compare image quality and performance with clinically indicated PET/CT examinations.
- Trial name
- NCT07857161
- Testing
- Omni 128cm PET/CT
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Non-small Cell Lung Cancer, Spread Through Air Space
Deep Learning Signature for Predicting Aggressive Histological Pattern in Resected Non-small Cell Lung Cancer
The purpose of this study is to evaluate the performance of a PET/ CT-based deep learning signature for predicting aggressive histological pattern in resected non-small cell lung cancer based on a multicenter prospective cohort.
- Conditions
- Non-small Cell Lung Cancer, Spread Through Air Space, Visceral Pleural Invasion, Lymphovascular Invasion
- Trial name
- NCT05925738
- Testing
- PET/CT-based Deep Learning Signature
- Where
- 3 sites in China
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Shanghai Pulmonary Hospital, Shanghai, China
Coronary Artery Disease
Quantitative Analysis of Functional CT Imaging of Coronary Atherosclerosis
The purpose of this prospective observational study is to evaluate the diagnostic and prognostic performance of a "one-stop" comprehensive coronary artery anatomy and function assessment for CAD.
- Trial name
- NCT04986410
- Testing
- CCTA, CT-MPI, CT-FFR, SPECT-MPI
- Where
- China
- Volunteers
- 640 people, healthy volunteers welcome
- Sponsor
- Qilu Hospital of Shandong University
Lung Cancer
Lung Cancer Screening Program in Mexico
This prospective study aims to detect early-stage lung cancer using low-dose computed tomography (LDCT) in Mexicans aged 50 or older who are current or former heavy smokers, non-smokers exposed to significant wood smoke, or…
- Trial name
- DETECTO (NCT06535451)
- Testing
- Screening
- Where
- Mexico
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Lung Inflammation, Sarcoidosis
Validation of the Analysis Methodology Behind the Use of Quantitative 18F-FDG PET/CT to Assess Lung Inflammation
The purpose of this study is to validate the method of analysing Positron Emission Tomography (PET) images to assess lung inflammation.
- Trial name
- VERIFY (NCT03312712)
- Testing
- PET/CT scan, LPS Challenge, Saline Challenge
- Where
- 2 sites in United Kingdom
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Alzheimer Dementia (AD), ALS - Amyotrophic Lateral Sclerosis
Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders
The goal of this study is to use ultra-high-resolution (UHR) PET imaging to better understand how the brain and spinal cord change in healthy aging and in neurological and psychiatric disorders such as Alzheimer's disease (AD)…
- Conditions
- Alzheimer Dementia (AD), ALS - Amyotrophic Lateral Sclerosis, Parkinson s Disease, REM Sleep Behavior Disorder (iRBD)
- Trial name
- NCT07509125
- Testing
- UHR PET/CT scan of the brain with ¹⁸F-FDG, UHR PET/CT scan of the brain with ¹⁸F-PE2I, UHR PET/CT scan of the brain with ¹⁸F-SynVesT-1
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Lung Cancer, Blood Biomarkers
AI for Lung Cancer Risk Definition in Computed Tomography Screening Programs
Low-dose computed tomography (LDCT) lung cancer (LC) screening can reduce mortality among heavy smokers, but there is a critical need to better identify people at higher risk and to reduce harms related to management of benign…
- Trial name
- NCT06320184
- Testing
- Artificial Intelligence risk model
- Where
- Italy
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano