Clinical trials: Computed Tomography Scan
Giant Cell Arteritis, Polymyalgia Rheumatica
Assessing Biomarker in Giant Cell Arteritis and Polymyalgia Rheumatic
The GCAIO study is an innovative, multimodal research initiative designed to enhance the understanding, diagnosis, and management of giant cell arteritis (GCA) and frequently associated polymyalgia rheumatica (PMR).
- Trial name
- GCAIO (NCT06460142)
- Testing
- Aortic/ cardiac magnetic resonance imaging, Vascular ultrasound, Transorbital Ultrasound
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Bonn
Maxillary Expansion
Root Resorption After Maxillary Expansion
The aim of this study will to evaluate the root resorption after RME by hyrax and hybrid hyrax appliances by using of cone beam computed tomography .
- Trial name
- NCT06059807
- Testing
- maxillary expansion
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Malignancies, Stomach Cancer
The Use of 18F-ALF-NOTA-PRGD2 PET/CT Scan to Predict the Efficacy and Adverse Events of Apatinib in Malignancies.
This is an open-label, single arm study to explore whether 18F-ALF-NOTA-PRGD2 PET/CT scan can predict the efficacy and adverse events of apatinib in patients with malignancies.
- Conditions
- Malignancies, Stomach Cancer, Non-small Cell Lung Cancer, Esophageal Cancer
- Trial name
- NCT03384511
- Testing
- Apatinib
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Shandong Cancer Hospital and Institute
Smoking
Low Dose Computed Tomography for Lung Cancer Screening
This study will evaluate the impact of a proactive, EHR-supported enrollment strategy that links LDCT-eligible smokers with an evidence-based intervention comprised of a web-based program and integrated text messaging.
- Trial name
- LDCT (NCT03084835)
- Testing
- Usual Care, WEB+TXT, WEB+TXT+TTS
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Computed Tomography
Data Collection of New Spectral CT Imaging Method
The purpose of the study is to collect data to evaluate utility of a next generation spectral CT system in a clinical setting.
- Trial name
- NCT07661706
- Testing
- Research CT
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- GE Healthcare
Lung Cancer, Blood Biomarkers
AI for Lung Cancer Risk Definition in Computed Tomography Screening Programs
Low-dose computed tomography (LDCT) lung cancer (LC) screening can reduce mortality among heavy smokers, but there is a critical need to better identify people at higher risk and to reduce harms related to management of benign…
- Trial name
- NCT06320184
- Testing
- Artificial Intelligence risk model
- Where
- Italy
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Istituto Nazionale dei Tumori, Milano
Paranasal Sinuses
Variants of Paranasal Sinuses in Nepali Population
The variants of paranasal sinuses (PNS)and nasal cavity are of clinical importance since some variants are susceptible to recurrent infection.
- Trial name
- NCT06683859
- Where
- Nepal
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Grande International Hospital, Nepal
Immediate Implants, Esthetic Zone
Radiographic Evaluation of The Labial Bone Dimensional Changes After Immediate Implant
For the dimension of the peri-implant buccal gap, a controversy is present whether complete bone formation labial to the implant.
- Conditions
- Immediate Implants, Esthetic Zone, Labial Bone Dimensional Changes, Without Labial Bone Grafting
- Trial name
- NCT05360693
- Testing
- immediate implant placement without bone grafting, immediate implant placement with socket bone grafting
- Where
- 2 sites in Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Cairo University
Lung Cancer, High-Risk Cancer
Taiwan Real-world LDCT Screening Behavior and Outcome Research for High Risk Subjects Based on Health Promotion Administration
Lung cancer is the leading cause of mortality in the world, and also in Taiwan.Despite the researches and availability in new therapies, it causes the highest mortality and is one of the most preventable cancers as well.
- Conditions
- Lung Cancer, High-Risk Cancer, Smoking, Pollution; Exposure
- Trial name
- TRIO (NCT05557487)
- Testing
- Low dose computed tomography
- Where
- 7 sites in Taiwan
- Volunteers
- 6,618 people, healthy volunteers welcome
- Sponsor
- Gee-Chen Chang
Atherosclerosis, Chronic Granulomatous Disease (CGD)
Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System
Background: Atherosclerosis, the arterial plaques or blockages that cause heart disease, develops in many people by the time they are in their mid-20s.
- Trial name
- NCT01063309
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Prostatic Neoplasms, Recurrence
PSMA PET/CT for Biochemical Recurrence Detection in Patients With Prostate Cancer
The aim of this study is to evaluate PSMA-PET for the detection of occult biological recurrence in patients with prostatic cancer referred to the Brest University Hospital.
- Trial name
- RB-PSMA (NCT04983459)
- Where
- France
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- University Hospital, Brest
Postmenopause
Bone Microstructure in Nasal Salmon Calcitonin Treated Postmenopausal Women
Calcitonin has been used for many years for treating osteoporosis in postmenopausal women. Recent data from the 2 years placebo-controlled QUEST study have shown a preservation of microarchitecture as measured by high resolution…
- Trial name
- NCT00372099
- Testing
- Salmon calcitonin
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Rene Rizzoli
Skeletal Class II Malocclusion, Mandibular Retrognathia
Fixed Versus Conventional Twin Block Appliances for Skeletal Class II Malocclusion
This study compares two types of dental appliances a fixed Twin Block appliance and a conventional (removable) Twin Block appliance used to treat a bite problem called skeletal Class II malocclusion in growing children and…
- Trial name
- NCT07687927
- Testing
- Conventional Twin Block Appliance
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Chronic Kidney Disease Mineral and Bone Disorder
Calcium Balance Studies in Children With CKD and on Dialysis
This is a novel, non-invasive method of assessing Ca balance by natural Ca isotope fractionation.
- Trial name
- Cal-Bal (NCT03285854)
- Testing
- Collection of blood, urine and stool samples
- Where
- United Kingdom
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Great Ormond Street Hospital for Children NHS Foundation Trust
Coronary Artery Disease, Coronary Atheroscleroses
Screening Coronary Artery Disease Using artiFicial intelligencE in Non-contrast Computed Tomography
This project aims to improve direct patient care by reducing the risks of futile exposure to ionizing radiation and iodinated contrast in patients referred for coronary computed tomography angiography
- Trial name
- SAFE-CT (NCT06438393)
- Testing
- CT coronary angiography and non-contrast CT
- Where
- Portugal
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Renal Cell Carcinoma
Yorkshire Kidney Screening Trial
Kidney cancer is the 8th most common cancer in Yorkshire. It has a poor survival rate, with only 6 out of 10 patients diagnosed with kidney cancer still alive after 5 years.
- Trial name
- YKST (NCT05005195)
- Testing
- Low dose abdominal computed tomography scan
- Where
- United Kingdom
- Volunteers
- 5,850 people, healthy volunteers welcome
- Sponsor
- University of Leeds
Root Resorption, Distal Caries
Frequency of External Root Resorption in Mandibular Second Molars Associated With Mandibular Impacted Third Molars Using CBCT
The prevalence of external root resorption and distal caries in mandibular second molars associated with impacted mandibular third molars will be detected in addition to the association of the risk factors.
- Trial name
- NCT03981367
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Cairo University
Orthodontic Anchorage, Power Arm Sliding
Comparison of Maxillary Canine Retraction Rate With and Without Power Arm
The goal of this split-mouth randomized clinical trial is to compare maxillary canine retraction with and without power arm during fixed orthodontic treatment.The main question it aims to answer is What are the differences in the…
- Conditions
- Orthodontic Anchorage, Power Arm Sliding, Direct Sliding, Orthodontic Space Closure
- Trial name
- NCT07836816
- Testing
- Split-mouth randomized clinical trial
- Where
- Bangladesh
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Tanzila Rafique
Lung Cancer
Low-dose Computed Tomography Screening for Lung Cancer in Relatives With Family History of Lung Cancer
Screening with the use of low-dose computed tomography (LDCT) reduces mortality from lung cancer. Relatives with family history of lung cancer are at increased risk of lung cancer compared to those without a family history in…
- Trial name
- NCT02519972
- Testing
- low dose computed tomography
- Volunteers
- 1,102 people, healthy volunteers welcome
- Sponsor
- Taichung Veterans General Hospital
Deep Bite Malocclusion
Efficacy of Aligners vs ABT and RCOS for Deep Bite Correction: CBCT Study
This prospective clinical trial aims to evaluate the efficacy of clear aligner therapy compared to two different treatment modalities - anterior bite turbos and reverse curve of Spee (RCOS) archwires - for the correction of…
- Trial name
- DB-CBCT (NCT07096401)
- Testing
- Reverse Curve of Spee Archwire, Anterior Bite Turbos, Clear Aligners
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University