Clinical trials: Computed Tomography Scan
Osteoporosis, Fracture Risk Assessment
Five-Year CT Follow-Up of Vertebral Fracture Risk Using Opportunistic Osteoporosis Screening
This study evaluates whether opportunistic osteoporosis screening using routinely acquired computed tomography (CT) scans improves fracture risk prediction compared with guideline-recommended FRAX-based screening from age 50.
- Conditions
- Osteoporosis, Fracture Risk Assessment, Osteoporotic Fracture of Vertebra
- Trial name
- NCT07487688
- Testing
- Opportunistic osteoporosis screening
- Where
- Germany
- Volunteers
- 2,799 people
- Sponsor
- Technical University of Munich
Bronchiectasis, Chronic Obstructive Pulmonary Disease
The Effect of Bronchiectasis on the Exacerbation and Mortality in COPD
Chronic obstructive pulmonary disease (COPD) is a chronic inflammatory disease of the airways and lungs that develops against harmful particles or gases with exacerbations.
- Trial name
- NCT03950531
- Testing
- No intervention
- Volunteers
- 122 people
- Sponsor
- Ministry of Health, Turkey
Chronic Subdural Hematoma
To Scan or Not to Scan: The Role of Follow-up CT Scanning for Management of Chronic Subdural Hematoma After Neurosurgical Evacuation
Chronic subdural hematoma (CSH) is one of the most common bleedings of the head. These hematomas develop after minor head trauma and increase in size over weeks.
- Trial name
- TOSCAN (NCT01624545)
- Testing
- cranial CT scan
- Where
- Switzerland
- Volunteers
- 368 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Pneumonia, Coronavirus Infection
LDCT in COVID-19 Pneumonia: a Prospective Moscow Study
Hypothesis: low-dose chest computed tomography, has the same accuracy for the diagnosis of pneumonia compared to the routine protocol. In total, 230 patients are planned to be enrolled in the study.
- Trial name
- LDCTiP (NCT04379531)
- Testing
- Low-dose Chest CT
- Where
- Russia
- Volunteers
- 230 people
- Sponsor
- Research and Practical Clinical Center for Diagnostics and Telemedicine Technologies of the Moscow Health Care Department
Breast Neoplasms
CTC Changes and Efficacy of Neoadjuvant Chemotherapy for Triple-negative Breast Cancer
Chemotherapy before operation for malignant tumors can reduce the size of tumors to a certain extent, even eliminate micrometastases.
- Trial name
- NCT04059003
- Testing
- Taxanes or/and anthracycline-based therapy
- Where
- 2 sites in China
- Volunteers
- 200 people
- Sponsor
- Shengjing Hospital
Bladder Cancer, Urothelial Carcinoma
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy
This research study is studying a positron emission tomography (PET) agent called 18F-fluciclovine to evaluate how well 18F-fluciclovine-PET scans determine the extent of muscle invasive bladder cancer (as compared to regular CT…
- Trial name
- NCT04018053
- Testing
- 18F-fluciclovine, PET/CT
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Brigham and Women's Hospital
Tracheal Stenosis
CT-Based Scoring System to Predict Surgical Need in Tracheal Stenosis (TSMAS Study)
This study aims to develop a CT-based scoring system to help predict whether patients with tracheal stenosis will require surgical treatment or can be managed with endoscopic procedures.
- Trial name
- NCT07086729
- Testing
- CT-Based Morphologic and Attenuation Scoring
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Ondokuz Mayıs University
Testicular Cancer
Low-Dose CT - Stage I Testicular Cancer
Patients with primary germ cell cancer of the testicles confined to the testis can avoid adjuvant treatment by entering a surveillance protocol.
- Trial name
- NCT03142802
- Testing
- Low-dose computed tomography (LDCT)
- Where
- Canada
- Volunteers
- 251 people
- Sponsor
- University Health Network, Toronto
Thrombosis Cardiac, Aortic Valve Disease
18F-GP1 PET-CT to Detect Bioprosthetic Aortic Valve Thrombosis
18F-GP1 binds with high affinity to the glycoprotein IIb/IIIa receptors on activated platelets. 18F-GP1 PET-CT has recently demonstrated favourable safety, pharmacokinetic, biodistribution and diagnostic performance for the in…
- Trial name
- NCT04073875
- Testing
- 18F-GP1
- Where
- United Kingdom
- Volunteers
- 53 people
- Sponsor
- University of Edinburgh
Aneurysm, 4D CT Scan
Pulsatility Aneurysmal Evaluation Process by Cerebral Dynamic CTA (Computed Tomography Angiography)
Intracranial aneurysm are frequent with a prevalence estimated over 2-5% in the general population. These are focal dilatations occuring in the cerebral vessels. They usually remain silent until complications occur.
- Trial name
- PULSAN (NCT03535181)
- Where
- France
- Volunteers
- 11 people
- Sponsor
- University Hospital, Brest
Coronary Artery Disease, Angina Pectoris
Study Comparing CT Scan and Stress Test in Patients With Known Coronary Artery Disease Hospitalized for Chest Pain
The purpose of this study is to determine whether coronary artery CT scanning or nuclear stress testing is better at diagnosing chest pain patients with known coronary artery disease to select appropriate candidates for coronary…
- Conditions
- Coronary Artery Disease, Angina Pectoris, Unstable Angina, Acute Coronary Syndrome
- Trial name
- PROSPECT-CAD (NCT01106612)
- Testing
- Coronary CT angiography, Myocardial perfusion imaging
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Montefiore Medical Center
Small Airways Diseases, Vaping
The Canadian Lung Outcomes in Users of Vaping Devices Study
Vaping is increasingly popular with both adolescent and adult Canadians, but the long-term health impacts remain unknown. We believe that the tools we currently have to detect lung disease in people who vape may be insufficient…
- Conditions
- Small Airways Diseases, Vaping, Vaping Related Disorder, Vaping Teens
- Trial name
- CLOUD (NCT06819969)
- Where
- 8 sites in Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Central Venous Catheter Thrombosis
Autopsy and Photon Counting Computed Tomography to Evaluate Thromboses Related to Central Venous Catheters
Central venous (CVC) is essential in modern healthcare but unfortunately associated with complications, including thrombosis. In a recently published study, it was showed that 12 out of 12 deceased patients had subclinical…
- Trial name
- PHOTO CAT (NCT06417541)
- Testing
- Diseased patients with an indwelling central venous catheter who is referred to autopsy, Living patients with an indwelling central venous catheter referred to a CT scan without iv contrast
- Where
- Sweden
- Volunteers
- 75 people
- Sponsor
- Thomas Kander
COVID-19 Pneumonia
RALE Versus CORADS/CT-Severity Score in COVID-19
Rationale Patients with severe coronavirus disease 2019 (COVID-19) frequently fulfill the criteria for acute respiratory distress syndrome (ARDS), with extensive and bilateral abnormalities on the chest radiography (CXR) and the…
- Trial name
- RALE-CORADS (NCT05047653)
- Testing
- RALE score vs. severity score
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Lung Cancer
Lung Cancer Screening Program in Mexico
This prospective study aims to detect early-stage lung cancer using low-dose computed tomography (LDCT) in Mexicans aged 50 or older who are current or former heavy smokers, non-smokers exposed to significant wood smoke, or…
- Trial name
- DETECTO (NCT06535451)
- Testing
- Screening
- Where
- Mexico
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Cancerologia de Mexico
Coronary Disease
Detection of Coronary Artery Calcification: Comparison of Volumetric and Electron Beam Computed Tomography
Electron beam computed tomography (EBCT) has been regarded as the state-of-the-art investigation for detecting and quantitating coronary artery calcification.
- Trial name
- NCT00001836
- Where
- United States
- Volunteers
- 213 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Cystic Fibrosis
Saline Hypertonic in Preschoolers + CT
The purpose of this study is to assess whether inhalation of 7% hypertonic saline (HS) twice daily for 48 weeks reduces structural lung disease as assessed by computed tomography (CT) in comparison with inhalation of 0.9%…
- Trial name
- SHIP-CT (NCT02950883)
- Testing
- Active Treatment Group 7% Hypertonic Saline, Control Group 0.9% Isotonic Saline
- Where
- 25 sites in United States, Australia and 7 more
- Volunteers
- 116 people
- Sponsor
- University of Washington, the Collaborative Health Studies Coordinating Center
Coronary Artery Disease
Cardiac Pathologies in Standard Thoracic CT Imaging
Modern high-end CT scanners with faster scan acquisition times now allow for routine assessment of cardiac pathologies, which could result in numerous incidental cardiac findings on standard thoracic CT angiography (CTA) scans.
- Trial name
- CaPaCT (NCT02904239)
- Where
- Netherlands
- Volunteers
- 221 people
- Sponsor
- Maastricht University Medical Center
Chronic Coronary Syndrome, Microplastics
Microplastics and Nanoplastics in Patients With Chronic Coronary Syndromes
The CCS-plastics is an investigator-initiated, prospective, multicenter study of patients undergoing coronary CT angiography (CCTA) for suspected or known chronic coronary syndromes (CCS) referred to invasive coronary angiography…
- Conditions
- Chronic Coronary Syndrome, Microplastics, Nanoplastics, Coronary Artery Disease
- Trial name
- CCS-Plastics (NCT07291609)
- Where
- 6 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Azienda Ospedaliera "Sant'Andrea"
Revision Total Knee Arthroplasty, Osteoarthritis, Knee
Gut Microbiome in Orthopaedics: Revision Total Knee Arthroplasty
Many patients who receive knee replacement surgery must return for a revision (or repeat) surgery due to ongoing pain, stiffness, infection, or implant loosening.
- Trial name
- GUMBO (NCT06951477)
- Testing
- Revision Total Knee Arthroplasty
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
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