Clinical trials: Computer Aided Diagnosis
Breast Neoplasms, Breast Diseases
Construction of a Benchmark for Breast Ultrasound AI Interpretation and Performance Evaluation of Multimodal AI Models
This single-center, retrospective, observational study aims to construct a standardized benchmark evaluation system for intelligent breast ultrasound image interpretation and to systematically assess the diagnostic performance of…
- Conditions
- Breast Neoplasms, Breast Diseases, Ultrasonography
- Trial name
- BUST-AI Bench (NCT07500428)
- Testing
- Multimodal AI Model Diagnostic Evaluation
- Where
- China
- Volunteers
- 1,380 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Breast Cancer
Case Collection Study for Collecting Images for the Development and Validation of Computer Aided Detection Software
The study objective is to assess the performance of the MammoDetector Pro to correctly mark biopsy-proven breast cancers imaged on the Siemens Mammomat Novation FFDM system compared to conventional film-screen mammography.
- Trial name
- NCT00756834
- Testing
- Screening
- Where
- United States
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Siemens Medical Solutions
Tuberculosis (TB)
Effectiveness of Computer-Aided Detection Chest X-Ray Screening for Improving Tuberculosis Diagnostic Yield in Chinese Primary Health Care Settings: Study Protocol for a Prospective Cluster Randomized Controlled Trial
The global incidence rate and mortality of tuberculosis (TB) pose a challenge to achieving the goals set out in the tuberculosis eradication strategy and the SDGs by 2030.
- Trial name
- NCT06963606
- Testing
- Artificial intelligence-assisted chest X-ray in TB screening, Routine doctors analyze the process of chest X-rays
- Where
- China
- Volunteers
- 22,000 people, healthy volunteers welcome
- Sponsor
- Xuelin Yang
Extrapyramidal Symptoms, Drug-induced Parkinsonism
A Computer-Assisted Tool for Objective Assessment of Extrapyramidal Symptoms
This prospective, single-center observational study aims to develop and validate a computer-assisted tool for the objective quantitative assessment of extrapyramidal symptoms (EPS).
- Conditions
- Extrapyramidal Symptoms, Drug-induced Parkinsonism, Akathisia, Drug-Induced, Tardive Dyskinesia (TD)
- Trial name
- NCT07715994
- Testing
- Computer-Assisted Objective Assessment of Extrapyramidal Symptoms
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
New Patient Use of Teledermatology Mobile App
Direct-to-patient Teledermatology and Computer-assisted Diagnosis
This study will examine access to dermatology care. The operational partner will implement a direct-to-new patient teledermatology clinical care pathway while the research will study the effects of that implementation, use data…
- Trial name
- NCT05128006
- Testing
- New patient teledermatology visit
- Where
- 3 sites in United States
- Volunteers
- 63,200 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Heart Murmurs, Mitral Valve Prolapse
Automatic Differentiation of Innocent and Pathologic Murmurs in Pediatrics
The purpose of this preliminary clinical study is to assess the quality of a computational algorithm that automatically classifies murmurs of phonocardiograms (PCGs) as either pathologic (AHA class I) or as no- or innocent (AHA…
- Conditions
- Heart Murmurs, Mitral Valve Prolapse, Systolic Murmurs
- Trial name
- NCT02512341
- Testing
- Computer Aided Auscultation (CAA)
- Where
- Canada
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- CSD Labs GmbH
Corneal Ectasia, Corneal Disease
Computer-aided Diagnosis of Ocular Diseases Based on Corneal Biomechanics
The purpose of this study is the investigation of biomechanical properties of the cornea using computer-aided data analysis. Currently, it is known that keratoconus and glaucoma are ocular disease that are associated with…
- Conditions
- Corneal Ectasia, Corneal Disease, Corneal Astigmatism, Keratoconus
- Trial name
- EyeTwin (NCT04475900)
- Testing
- Corneal biomechanics (Corvis ST, Oculus, Wetzlar, Germany), Corneal topography and tomography (Pentacam, Oculus, Wetzlar, Germany), Optic nerve head measurement
- Where
- Germany
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Technische Universität Dresden
Osteoarthritis of the Knee
Computer Aided Gap Balancing Improves Sagittal Stability and Outcomes for Cruciate-Retaining Total Knee Arthroplasty
Computer Aided Surgery in total knee arthroplasty improves knee stability and functional outcomes more than conventional total knee arthroplasty.
- Trial name
- NCT00865865
- Testing
- Computer aided total knee arthroplasty, Conventional total knee arthroplasty
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Breast Cancer
Computer-Aided Breast Cancer Detection in Women Undergoing Screening Mammography
RATIONALE: A computer-aided detection program may help doctors find breast cancer sooner, when it may be easier to treat, in women undergoing screening mammography.
- Trial name
- NCT00450359
- Testing
- breast imaging study, comparison of screening methods, radiomammography
- Where
- 4 sites in United Kingdom
- Volunteers
- 30,000 people, healthy volunteers welcome
- Sponsor
- Aberdeen Royal Infirmary
Cognitive Impairment
Pilot Testing a New Computer-based Screening Tool to Detect Cognitive Impairment
A computer-based neuropsychological assessment tool is being developed to help primary care physicians detect neurological and psychiatric disorders.
- Trial name
- NCT01220674
- Testing
- cognitive testing
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Breast Cancer, Breast Neoplasms
The Diagnostic Efficacy of Computer-Aided Detection (CAD) in Full-Field Digital Mammography (FFDM)- A Prospective Study
The purpose of this study is to evalute whether CAD (computer-aided detection) in FFDM (full-field digital mammography) can facilitate the detection rate of breast cancer on mammography compared with FFDM without CAD.
- Trial name
- NCT00173303
- Where
- Taiwan
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Lung Cancer
Evaluation of Contextflow DETECT Lung CT Nodule Detection Software in Chest CT Scans
contextflow DETECT Lung CT is a Artificial Intelligence (AI)-based computed-aided detection (CADe) system, intended to support radiologists in the detection of lung nodules in chest computed tomography (CT) scans.
- Trial name
- NCT05481762
- Testing
- Aided read with contextflow DETECT Lung CT
- Where
- Austria
- Volunteers
- 337 people, healthy volunteers welcome
- Sponsor
- contextflow GmbH
Barrett Esophagus, Barrett Adenocarcinoma
Real-time Computer Aided Detection of Barrett's Neoplasia
In the real-time pilot study, the performance of a recently developed Computer Aided Detection (CADe) system will be investigated in 30 patients during real-time live endoscopic examination.
- Trial name
- NCT05628441
- Testing
- Computer Aided Detection system for Barrett's neoplasia
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Motivational Interviewing, Computer-Aided Design
Assessment of the Effect of Periodontal Disease Prediction System on Oral Hygiene Motivation
The aim of this trial is to evaluate the effect of patient specific periodontal disease prediction (PDP) system, a part of motivational interview, (MI) on probing depth (PD), Rustogi modified Navy Plaque Index (RMNPI), and…
- Conditions
- Motivational Interviewing, Computer-Aided Design, Periodontal Diseases
- Trial name
- NCT06577246
- Testing
- scaling root planing, Three-Dimensional Animation (video1-2), Three-Dimensional Animation (video 3)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Trauma, Diabetes
Long Term Clinical Evaluation of SLS Transtibial Sockets
The overall long-term goal of this project is the development of a clinically practical system for rapid prosthetic limb provision that integrates computer-aided design with solid freeform fabrication techniques.
- Trial name
- NCT00167570
- Testing
- Prosthetic socket fabricated using selective laser sintering
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Colon Adenoma, Colorectal Cancer
Clinical Efficacy Evaluation of a Computer-aided Colonoscopy as Compared With the Standard Colonoscopy.
Colonoscopy is clinically used as the gold standard for detection of colorectal cancer (CRC) and removal of adenomatous polyps of the colon and rectum.
- Trial name
- NCT05240625
- Testing
- "aetherAI" Computer-aided Polyp Detection (CADe) Systems for Colonoscopy, Standard colonoscopy
- Where
- Taiwan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Diagnosis
The Impact of Large Language Models on Diagnostic Reasoning Among LLM-Trained Medical Doctors
This study aims to evaluate whether large language model-trained medical doctors demonstrate enhanced diagnostic reasoning performance when utilizing ChatGPT-4o alongside conventional resources compared to using conventional…
- Trial name
- NCT06774612
- Testing
- ChatGPT-4o
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Lahore University of Management Sciences
Endodontically Treated Teeth
A 3-Year Clinical Evaluation Of Endocrown Restorations With Two Different Materials
The clinical performance of two different materials in endodontically treated teeth produced with CAD/CAM system will be evaluated and compared.
- Trial name
- NCT06311422
- Testing
- resin nanoceramic block, zirconia-reinforced lithium silicate
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Dental Plaque
Analyzing the Effect of Air Polishing on Tooth Surfaces With Two Imaging Methods
Micro-CT is a non-destructive imaging method with high resolution and allows to examine all tooth structures individually. Pre- and post-application images obtained by micro-CT can be superimposed and differences can be precisely…
- Trial name
- NCT05196490
- Testing
- Micro-CT, CAD/CAM
- Where
- Turkey (Türkiye)
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Recession, Periodontal Diseases
Use of Scaffolds for Treatment of Gingival Recession Associated With Interproximal Tissue Deficiency
This study will seek to evaluate the predictability and efficacy of a Computer Aided Design-Computer Aided Manufacturing and additively manufactured polycaprolactone and hydroxyapatite scaffolds in these defects compared to…
- Trial name
- NCT03232788
- Testing
- Bone regeneration, Collagen membrane, Scaffold
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo