Clinical trials: Concentration
Healthy
A Healthy Volunteer Trial to Gain Information About the Blood Concentrations of PF-06412562 After Oral Administration of a Modified Release Formulation in Fasted and Fed Conditions
The study is designed to understand the blood concetration of PF-06412562 and its metabolite, PF-06663872, following a single oral dose of a modified release formulation.
- Trial name
- NCT02201511
- Testing
- 3 mg PF-06412562 MR tablets_Fasted, 2 x 15 mg PF-06412562 MR tablets_Fasted, 2 x 15 mg PF-06412562 MR tablets_Fed
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Acute Coronary Syndrome, Myocardial Infarction
Hepatocyte Growth Factor (HGF) Concentration in Myocardial Infarction
This is the continuation of previous study (registration number: NCT00844987) which revealed that hepatocyte growth factor (HGF) is a very early, good marker of myocardial injury and prognostic factor for post myocardial…
- Trial name
- NCT01233336
- Where
- Poland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Warsaw, Poland
ADHD, Child, Only
A Randomized Controlled Study of Family Based EF Training for Schoolage Children With ADHD
The goal of this study is to provide a new treatment approach for schoolage children with ADHD, which could facilitate the EF developing well to achieve better outcome.
- Trial name
- NCT05025501
- Testing
- Family based Executive Function Training
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Kidney Transplantation, Rejection
Monitoring Concentration and Pharmacodynamic Effects of Tacrolimus in Peripheral Blood Lymphocytes of Kidney Transplant Recipients
Therapeutic drug monitoring (TDM) of immunosuppressive drugs is used to improve the immunosuppressive effect while minimizing the toxicity related to exposition to high serum levels.
- Trial name
- NCT03425071
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
Male Circumcision
High Volume Caudal Study
The primary objective is to evaluate the effect of clonidine on the duration of analgesia provided by a high volume-low concentration caudal block for pediatric aurgical procedres.
- Trial name
- NCT04263064
- Testing
- High Volume-Low Concentration without Clonidine, High Volume-Low Concentration with clonidine
- Where
- United States
- Volunteers
- 129 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Healthy Volunteers
Changes in Perception and Cognition During a Meditation Retreat
This study aims at assessing neuro-behavioral changes occuring during an intensive ten days meditation retreat. The investigator will study changes in tactile, auditory and pain perceptions as well as changes in cognitive and…
- Trial name
- LONGIMED (NCT04449913)
- Testing
- 10 days intensive meditation retreat, Waiting for a 10 days intensive meditation retreat
- Where
- France
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Attention Deficit Hyperactivity Disorder
An Open Label Phase I/II Study of the Safety and Dopamine Transporter Binding Properties of C-11 Altropane in Normal Human Subjects and in Subjects With ADHD
The primary objective of this study is to evaluate the Binding Potential in subjects with ADHD and adults without ADHD: the intent being to demonstrate that C-11 Altropane PET can be used to differentiate adults with ADHD from…
- Trial name
- NCT00302380
- Testing
- PET imaging using C-11 altropane as the ligand.
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Reflux Oesophagitis
Effect of 5, 10 or 25 mg of YF476 Daily for 14 Days on Stomach Acidity in Healthy Volunteers
The objective of the study was to assess whether the tolerance to the effect of YF476 on gastric pH observed with repeated doses in a previous study in healthy volunteers can be avoided by using smaller doses of YF476.
- Trial name
- NCT01597674
- Testing
- YF476
- Where
- United Kingdom
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Trio Medicines Ltd.
Disturbance of Activity and Attention
Comparison of Attention of Physician After Outpatient Clinic
The attention and clinical performance of physician might be decreased after outpatient clinic session compared to those measured before outpatient clinic.
- Trial name
- NCT01665313
- Where
- South Korea
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Depression, Insomnia
Preliminary Study on the Development and Reliability and Validity of Attention Rating Scale
This study, based on preliminary experimental results, literature review, and expert consultations, developed the Attentional Rating Scale (ARS).
- Conditions
- Depression, Insomnia, Attention Disturbances, Healthy
- Trial name
- NCT06207279
- Testing
- rating
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Peking University Sixth Hospital
Lung Injury, Acute, Symptoms and Signs
Pulmonary and Inflammatory Responses Following Exposure to a Low Concentration of Ozone or Clean Air
Purpose: The primary purpose of this study is to measure pulmonary function, symptoms, and pulmonary inflammatory responses in healthy young adults during and immediately after exposure to a low concentration of ozone (0.070 ppm)…
- Conditions
- Lung Injury, Acute, Symptoms and Signs, Neutrophilia Acute
- Trial name
- LOCONOZ2 (NCT05680831)
- Testing
- 0.070 ppm ozone concentration, Clean air (0.0 ppm ozone)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Martin W. Case
Attention Deficit Hyperactivity Disorder
Food Additives Effects on EEG Profiles in College Students With ADHD
The purpose of this study is to examine the effects of food additives on college students with ADHD. This study could potentially answer an important question which still remains unanswered as to whether certain food additives…
- Trial name
- NCT03342469
- Testing
- Artificial Food Coloring
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- American University
Vitamin D Deficiency, Cardiometabolic Risk Factors
Comparison of Sunlight Exposure and Vitamin D Supplementation on Serum 25-hydroxyvitamin D Levels
This study aimed to compare the effects between sunlight exposure and oral vitamin D supplementation on serum 25-hydroxyvitamin D concentration and metabolic markers in Korean young adults.
- Trial name
- NCT03310242
- Testing
- Sunlight Exposure, Vitamin D Supplementation
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Liver Cirrhosis
A Study to Investigate the Blood Concentrations of 4 Different Oral Doses of Zibotentan in Healthy Non-Asian and Japanese Participants
This study aim to assess the Pharmacokinetics of Zibotentan in Healthy Non-Asian and Japanese Participants.
- Trial name
- NCT06715670
- Testing
- Zibotentan
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Sports Injury
The Gender-Specific Effect of Different Instruction Training
Feedback is incorporated into training programs to prevent injuries. The superiority of several feedback techniques is still debated and there is a need for gender specific studies.
- Trial name
- NCT06746454
- Testing
- Video Instructed Training Group, Verbal Combined Focus Instructed Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Healthy, Pharmacokinetics of ASP1941
A Study to Assess the Effect of ASP1941 and Mitiglinide on Their Plasma Concentration
This study is to assess the pharmacokinetic interaction between ASP1941 and Mitiglinide calcium hydrate in healthy volunteers.
- Conditions
- Healthy, Pharmacokinetics of ASP1941, Pharmacokinetics of Mitiglinide
- Trial name
- NCT01403818
- Testing
- ASP1941, Mitiglinide calcium hydrate
- Where
- Japan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Astellas Pharma Inc
Attention Deficit Hyperactivity Disorder
Metabolic Pathway of Tryptophan and Executive Dysfunction in Children With Attention Deficit Hyperactivity Disorder
The present project is to identify the relationship between ADHD and the metabolites of tryptophan.
- Trial name
- NCT03901859
- Where
- Taiwan
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Healhty
The Effect of Oral Oxytocin and Atosiban on Social Attention
The main aim of the present study is to investigate whether orally (lingual spray) administered oxytocin influences human social attention and behaviors via oxytocin receptors and whether its effects are dose- and task-dependent.
- Trial name
- OTAtosiban (NCT07093060)
- Testing
- Oxytocin lower dose (24IU), Oxytocin higher dose (48IU), Atosiban
- Where
- China
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Socioemotional Development, Cognitive Ability
Early Institutionalization Intervention Impact Project
The purpose of this study is to determine the effects of early intervention (placement into foster care, and a caregiving training) on physical, cognitive, social and brain development and psychiatric symptomatology in children…
- Conditions
- Socioemotional Development, Cognitive Ability, Behavioral and Neural Patterns of Attention, Brain Function
- Trial name
- EI-3 (NCT04165746)
- Testing
- Foster Care, Caregiving Intervention
- Where
- Brazil
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital
Analysis of Anaesthesia Depth
Prediction of Propofol Effect Compartment Concentrations
The goal of this observational study is to learn about the prediction of the effect of Propofol by means of EEGs. The main questions it aims to answer are: Develop models that can reliably predict the effect of Propofol Select…
- Trial name
- Propo2022 (NCT05940142)
- Where
- Austria
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Karl Landsteiner University of Health Sciences
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