Clinical trials: Concentration
Obesity, Pharmacokinetics
Effect of Weight and/or Obesity on Sulfamethoxazole and Trimethoprim Concentrations
This study will find how weight affects the dosing of a drug called sulfamethoxazole and trimethoprim. Currently, the amount of sulfamethoxazole and trimethoprim a patient receives is the same regardless of the patient's weight.
- Conditions
- Obesity, Pharmacokinetics, MRSA, Tuberculosis
- Trial name
- NCT01167452
- Testing
- Sulfamethoxazole/trimethoprim
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Texas Tech University Health Sciences Center
Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder
Network Control TMS fMRI
This study uses different types of functional magnetic resonance imagining (fMRI) to generate individual transcranial magnetic stimulation (TMS) targets.
- Conditions
- Attention Deficit Hyperactivity Disorder, Attention Deficit Disorder, Working Memory
- Trial name
- NCT05736458
- Testing
- Transcranial Magnetic Stimulation (TMS), High controllability TMS target
- Where
- United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke, Cognitive and Attention Disorders and Disturbances
The RenAtt Method for Diagnosing and Treating Attention Problems After Stroke and Brain Injury, Further Validation of RehAtt® DiSTRO Assessment of Cognitive and Visual Function
Stroke is one of the most common long-term disabilities in the world. Despite better access to more effective acute treatment, WHO reports a prediction of almost a doubling of disability-adjusted life-years (DALYs) in 2050.
- Conditions
- Stroke, Cognitive and Attention Disorders and Disturbances, Digital Health, Screening Strategy
- Trial name
- NCT07762274
- Testing
- Oxford Cognitive Screen
- Where
- 3 sites in Italy, Sweden and 1 more
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Umeå University
Sports Fatigue
Effects of Dual-site Anodal Transcranial Direct Current Stimulation on Attention, Decision-making and Working Memory During Sports Fatigue in Elite Soccer Athletes
Investigation of the effects of dual-site anodal transcranial direct current stimulation over the dorsolateral prefrontal cortex or primary motor cortex on attention, decision-making and working memory during sports fatigue in…
- Trial name
- NCT06594978
- Testing
- dual-site anodal tDCS over the M1, dual-site anodal tDCS over the DLPFC
- Where
- China
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Beijing Sport University
ADHD
Impact of A Multidimensional Health Education Program on Attention Deficit Hyperactivity Disorder (ADHD)
To measure the impact of a multidimensional health education program on patients' adherence to the healthy life style and behavioral therapy , and to correlate it with severity of ADHD symptoms
- Trial name
- ADHD (NCT06406335)
- Testing
- Health education program
- Where
- Egypt
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Inattention, Cognitive Training
RECOGNeyes Gaze-Control Training
RECOGNeyes is a computer game developed by members of the research team to improve attention in people who find it hard to "keep their eyes on the task".
- Conditions
- Inattention, Cognitive Training, Cognitive Control, Oculomotor Dysfunction
- Trial name
- NCT06691646
- Testing
- Gaze-control training game
- Where
- United Kingdom
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Chronic Pain
Effects of Pain on Driving Performance and Cognition.
It has been suggested that cognitive functioning is impaired in chronic pain patients. Since most of these pain patients engage in daily activities including driving, it was hypothezised that they may have an increased risk of…
- Trial name
- NCT00189046
- Testing
- driving and laboratory tests
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Infections, Rotavirus
Evaluate Safety & Immunogenicity of 2 or 3 Doses of GSK HRV Vaccine in Healthy Infants in South Africa
The purpose of this study is to determine the appropriate regimen of GSK HRV vaccine for concomitant administration with EPI vaccines to infants in South Africa.
- Trial name
- NCT00383903
- Testing
- HRV vaccine
- Where
- 6 sites in South Africa
- Volunteers
- 472 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fibromyalgia, Systemic Lupus Erythematosus
Membrane Polyunsaturated Fatty Acid Content in Fibromyalgia and Systemic Lupus Erythematosus (SLE)
Polyunsaturated omega-3 fatty acids (ω3 PUFAs) are essential nutrients. Studies indicate that the incidence of Major Depression (MD) is inversely related to the consumption of fish (which are rich in ω3-PUFAs) and to the…
- Trial name
- NCT01460680
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Tel-Aviv Sourasky Medical Center
Attention Deficit Hyperactivity Disorder
Clinical Trial to Evaluate the Efficacy and the Tolerance of an Omega 3 Fatty Acids Supplementation in ADHD Children
Principal focus is to evaluate the effects of omega 3 fatty acids supplementation on the ADHD children's behaviour during 12 weeks on two years.
- Trial name
- NCT00770627
- Testing
- Omega 3 caps
- Where
- 2 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Laboratoires URGO
ADHD
Evaluation of Use of Brain Activity Monitoring Dynamics in ADHD
This study evaluates the ability to support diagnosis and monitor of the dynamics in ADD/ADHD subjects with an easy to use EEG Device.
- Trial name
- NCT02625805
- Testing
- EEG monitoring (MindWave by NeuroSky), EEG monitoring (EPOC by Emotiv), Methylphenidate
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Brainmarc Ltd.
ADHD, Executive Dysfunction
Virtual Reality (VR) Diagnostic Tool for Attention Deficits/Hyperactivity Disorder (ADHD)
Attention deficit/ hyperactivity disorder (ADHD) is a common neurodevelopmental disorder. The common diagnostic of ADHD is based on psychiatric examination and interview.
- Trial name
- New (NCT04337905)
- Testing
- ADHD-VR diagnosis tool
- Where
- Indonesia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tjhin Wiguna
Healthy
A Healthy Volunteer Trial to Gain Information About the Blood Concentrations of PF-06412562 After Oral Administration of a Modified Release Formulation in Fasted and Fed Conditions
The study is designed to understand the blood concetration of PF-06412562 and its metabolite, PF-06663872, following a single oral dose of a modified release formulation.
- Trial name
- NCT02201511
- Testing
- 3 mg PF-06412562 MR tablets_Fasted, 2 x 15 mg PF-06412562 MR tablets_Fasted, 2 x 15 mg PF-06412562 MR tablets_Fed
- Where
- Belgium
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Pfizer
Attention Deficit Hyperactivity Disorder
System for Determining Ideal Drug Doses for ADHD - Stages 1 and 2
The goal of this study is to create a formal, quantitative methodology to determine what is the most beneficial dose of Central Nervous System (CNS) stimulant (Ritalin, methylphenidate) to improve cognitive and behavioral…
- Trial name
- NCT03523663
- Testing
- no intervention. measure eye movement data
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Type 2 Diabetes
Study of Metformin Pharmacogenetics in Twins
The trough concentration of metformin will be examined in monozygotic and dizygotic twins. Current twin study will determine the total weight of genetics on the trough concentration of metformin.
- Trial name
- NCT01869621
- Testing
- Metformin
- Where
- Denmark
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Attention Deficit Hyperactivity Disorder
Animal Assisted Intervention With Dogs for Children With ADHD
This pilot study aims to replicate results of a previously studied novel, non-pharmacological psychosocial intervention for children with ADHD, utilizing an Animal Assisted Intervention with therapy dogs combined with traditional…
- Trial name
- PACK-PM (NCT05102344)
- Testing
- Behavioral Social Skills Training, Animal Assisted Intervention
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of California, Irvine
Cognitive Performance
Evaluation of the Effects of Berry Leaf Extract on Cognitive Processing in Healthy Elderly Adults
This study aims to explore the positive effect of a dietary supplement composed of berry leaf extract on the cognitive performance and regulation of stress, mood, sleep and fatigue in healthy elderly adults with self-reported…
- Trial name
- SLE (NCT06819163)
- Testing
- Berry leaf extract
- Where
- Belgium
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Seppic
Chronic Kidney Disease
Study of the Influence of Liver Function on Blood Concentrations of Runcaciguat in Participants With Different Degrees of Liver Impairment
Researchers are looking for a better way to treat people with chronic kidney diseases. Before a treatment can be approved for patients to take, researchers do clinical studies to better understand its safety and what happens to…
- Trial name
- NCT04820621
- Testing
- Runcaciguat (BAY1101042)
- Where
- Germany
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Bayer
Attention, Memory
The Impact of Supplementation With Hericium Erinaceus (Lion's Mane) Extract on Cognitive Functioning
The goal of this study is to determine whether supplementation with Hericium erinaceus (Lion's Mane) extract enhances selected cognitive functions in healthy, actively working, middle-aged women.
- Conditions
- Attention, Memory, Cognitive Function and Well-Being
- Trial name
- HECOG (NCT07405632)
- Testing
- Hericium erinaceus Supplementation
- Where
- Poland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Social Sciences and Humanities, Warsaw
Attention Deficit Hyperactivity Disorder
Adults With Attention Deficit Hyperactivity Disorder (ADHD): Validation of a Clinical Interview and Screening Instruments in French
ADHD is a neurodevelopmental disorder that affects about 5% of school-age children and 3.5% of adults worldwide. This condition is under-recognised in France and other European countries and, therefore, under-diagnosed.
- Trial name
- NCT01553695
- Testing
- questionary
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
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