Clinical trials: Concentration
Non-cardiac Disease
Impact of Hospitalization on High-sensitivity Cardiac Troponin T Concentrations Depending on Disease Severity
We aim to examine, whether hospitalization is associated with higher high-sensitivity cardiac troponin T (hs-cTnT) serum concentrations in patients without a cardiac disease.
- Trial name
- NCT04963400
- Testing
- Analysis of hs-cTnT serum concentration at hospitalization, Analysis of hs-cTnT serum concentration after discharge
- Where
- Germany
- Volunteers
- 177 people
- Sponsor
- University of Leipzig
Delirium, Dementia, Amnestic, Cognitive Disorders, Arthroplasty, Hip Replacement
Cerebral Regional Oxygen Saturation and Markers of Brain Damage During Primary Hip Arthroplasty
Postoperative Cognitive Disorders (POCD) are common in hospitalized people > 60 year old, especially in orthopedic patients. Etiology of POCD is complex, and in some aspects still remains unclear.
- Trial name
- NCT02342236
- Testing
- cemented or cementless type of hip prothesis
- Where
- Poland
- Volunteers
- 18 people
- Sponsor
- Military Institute od Medicine National Research Institute
Attention Deficit Hyperactivity Disorder
Procedural Learning in Participants With ADHD
Skill acquisition refers to the process of improvement of performance following practice experience. This process is the basis for generation of a long-lasting memory.
- Trial name
- NCT00446537
- Testing
- Methylphenidate
- Where
- Israel
- Sponsor
- Shaare Zedek Medical Center
Psychotic Disorder
Yoga and Aerobic Exercise in Psychosis
The current study aims to evaluate the impacts of yoga and aerobic exercise on neuro-cognitive function, symptoms and brain changes in early psychosis.
- Trial name
- YEP (NCT01207219)
- Testing
- Yoga therapy, Aerobic exercise
- Where
- Hong Kong
- Volunteers
- 140 people
- Sponsor
- The University of Hong Kong
ADHD
Working Memory Training and Neurofeedback for Children With ADHD, a Pilot Study
This pilot study compares the effect of working memory training and neurofeedback in non-medicated children age 7 to 13 years with ADHD.
- Trial name
- NCT02754336
- Testing
- Cogmed Robomemo, working memory training, Othmer, neurofeedback
- Where
- Norway
- Volunteers
- 6 people
- Sponsor
- Helse Stavanger HF
Ageing
Attention and Memory Training With Video Games in Old Age
Neuroplasticity-based approaches seem very promising to maintain cognitive health in older adults and postpone the onset of cognitive-decline and dementia symptoms. The aims of this project are threefold: 1.
- Trial name
- AGEGAME (NCT02796508)
- Testing
- Experimental: Non-action video game training, Active Comparator: Non-cognitive video game training
- Where
- Spain
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Educación a Distancia
Healthy, Cognitive Change
Cognitive Augmentation Via Multimodal Sensing and Auricular Neurostimulation
The goal of this clinical trial is to extend this period of optimal cognitive performance by applying neurostimulation to buffer health volunteers against the effects of increased levels of stress, distraction, and cybersickness.
- Conditions
- Healthy, Cognitive Change, Effects of External Neurostimulation on Cognition
- Trial name
- CAMSAN (NCT06782360)
- Testing
- Active Neurostimulation
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- OpenBCI
ADHD, Attention Deficit Hyperactivity Disorder
Healthy Lifestyle in Adults With Attention Deficit Hyperactivity Disorder
The purpose of this study is to understand the relationship between ADHD and the overall health of someone with ADHD. People who have ADHD have trouble paying attention, concentrating, organizing, and planning.
- Trial name
- NCT00879320
- Where
- United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Labor Pain
Exploring the Optimal Concentration of Lidocaine Test Dose for Labor Analgesia
This study aims to compare the analgesia effects and side effects of different concentrations of test dose lidocaine (1.5% lidocaine 3 ml, 1.0% lidocaine 5 ml, 0.5% lidocaine 10 ml) in labor analgesia, so as to provide a…
- Trial name
- NCT06819579
- Testing
- 1.5% Lidocaine, 1.0% Lidocaine, 0.5% Lidocaine
- Where
- China
- Volunteers
- 99 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Crohn Disease, Ulcerative Colitis
The Evaluation of Injection Site Pain and Adherence in Patients Switching From a Low To High Concentration Adalimumab (AVT-02) Across Multiple Indications.
The purpose of the Phase IV study is to investigate the effects of both Volume and Citrate on Injection Site Pain (ISP), adherence, patient satisfaction, Quality of Life, and Disease Assessment in the Canadian Adalimumab Market.
- Conditions
- Crohn Disease, Ulcerative Colitis, Rheumatoid Arthritis, Ankylosing Spondylitis
- Trial name
- EASE PAIN (NCT05913817)
- Testing
- AVT02 (Alvotech Biosimilar to Adalimumab)
- Where
- Canada
- Volunteers
- 324 people
- Sponsor
- Jamp Pharma Corporation
IVF
Effect of Reducing the Oxygen Concentration From 5% to 2% on ICSI Outcome
To assess the effect of reducing the oxygen concentration from 5% to 2% on Intracytoplasmic sperm injection (ICSI) outcome.
- Trial name
- NCT05924048
- Testing
- Reducing the Oxygen Concentration From 5% to 2%
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- International Islamic Center for Population Studies and Research
Kidney Transplantation
Mycophenolate-Based Therapy for Kidney Transplant Recipients Without HLA-DQ Mismatch
The goal of this clinical trial is to learn if calcineurin-inhibitor therapy (a drug commonly used to prevent rejection) can be safely stopped in kidney transplant recipients with a relatively low risk of rejection (being…
- Trial name
- MyQURE (NCT06493526)
- Testing
- Withdrawal of calcineurin-inhibitor, continue on concentration-controlled mycophenolate mofetil and corticosteroids.
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- University Hospital, Antwerp
Malignant Hyperthermia
Effectiveness of Carbon Filters to Reduce the Anesthetic Gas Concentration in an Anesthetized Patient
Malignant hyperthermia is a potentially fatal inherited disorder triggered by exposure to volatile anesthetic gases, most commonly recognized in children during anesthesia. Carbon filters have been used to scavenge various gases.
- Trial name
- NCT01624558
- Testing
- In-line Carbon filter (Vapor-Clean)
- Volunteers
- healthy volunteers welcome
- Sponsor
- Johns Hopkins University
ADHD
Evaluating a Digital Cognitive Training Intervention in Adults With ADHD
The goal of this clinical trial is to evaluate whether a digital cognitive training program can reduce symptoms of ADHD, improve executive functioning, and decrease problematic internet use in adults aged 18-65 with a diagnosis…
- Trial name
- NCT07050225
- Testing
- Digital Cognitive Training, Digital Non-cognitive Training Intervention
- Volunteers
- 52 people
- Sponsor
- McMaster University
Attention-Deficit Hyperactivity Disorder(ADHD)
A Trial to Evaluate the Efficacy and Safety of EB-1020 in Pediatric Patients With ADHD
The purpose of this study is to evaluate the efficacy and examine the safety of two doses of EB-1020 QD XR capsule administered once daily orally in pediatric ADHD patients.
- Trial name
- NCT07086313
- Testing
- EB-1020 (Centanafadine) low dose, EB-1020 (Centanafadine) high dose
- Where
- Japan
- Volunteers
- 315 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Caudal Block for Postoperative Analgesia
Effect of Adding Different Concentrations of Dexmedetomidine to Bupivacaine in Caudal Block for Pediatrics
Pain is one of the medical problems frequently misdiagnosed, undertreated, and poorly under-stood, particularly in children.Poor pain management during childhood may have long-term deleterious impacts, including damaging…
- Trial name
- NCT06668220
- Testing
- Dexmedetomidine, Bupivacain
- Volunteers
- 50 people
- Sponsor
- Assiut University
Blood Bupivacaine Concentration
Blood Bupivacaine Concentration After Regional Block Applications in Pediatric Patients
Analgesia methods such as systemic analgesics, quadratus lumborum block, and transversus abdominis plane block are used for pain management after lower abdominal surgery.
- Trial name
- NCT07256535
- Testing
- Transversus Abdominis Plane Block, Quadratus Lumborum Block
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people
- Sponsor
- Kocaeli University
Potential Abnormality of Glucose Tolerance, Appetitive Behavior
Acute Effects of Cookies Containing 2.5 g Spirulina on Postprandial Glycemic and Insulin Responses
This study investigated the effects of cookies containing 2.5 g Spirulina on postprandial glycemic and insulin responses.
- Conditions
- Potential Abnormality of Glucose Tolerance, Appetitive Behavior, Blood Pressure
- Trial name
- NCT05484323
- Testing
- Glucose as reference food, White bread, Cookie containing 0 g spirulina
- Where
- Greece
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Agricultural University of Athens
Bacteremia by Enterobacteriaceae
Study of the Impact of the Minimum Inhibitory Concentration and Susceptible Cut-off Points (CLSI, EUCAST, and Pharmacokinetics/Pharmacodynamics)in Prognosis of Bacteremia by Enterobacteriaceae
Provide scientific and validated data to help International Authorities to set susceptible to antibiotics cut-off points in bacteremia by Enterobacteriaceae
- Trial name
- BACTERIEMIA (NCT02005159)
- Testing
- Microbiological studies
- Where
- 14 sites in Spain
- Volunteers
- 1,064 people
- Sponsor
- Fundación Pública Andaluza Progreso y Salud
Post Intensive Care Syndrome, Depression
Companion Dog Walking for ICU Survivor Health
The goal of this clinical trial is to determine the feasibility and acceptability of a randomized controlled trial comparing a pet dog walking intervention to an attention control education intervention in adult intensive care…
- Conditions
- Post Intensive Care Syndrome, Depression, Anxiety, Quality of Life
- Trial name
- POOCH (NCT05820308)
- Testing
- Companion Dog Walking, Attention Control Group
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- University of Missouri, Kansas City
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